S6E5: Amanda Randles: A Check-Engine Light for the Heart
Release Date: 07/15/2025
Science in Parallel
On July 15, 2021, Science in Parallel launched a six-episode season celebrating the 30th anniversary of the Department of Energy Computational Science Graduate Fellowship program. After five years, 45 episodes and 55 guests, we’re celebrating our coverage of computational collaboration and creativity, exploring research on energy, medicine, artificial intelligence, quantum science and more. You’ll meet: Science in Parallel’s host : Senior Principal Scientist, GSK : Professor of Biomedical Engineering, Duke University : Chemist/Staff Scientist/Engineer, Lawrence Berkeley National...
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Recently four alumni of the (DOE CSGF) met and discussed quantum science and quantum computing. They also shared how the DOE CSGF helped their careers and their advice for new fellows and other early career computational scientists. To celebrate the 35th anniversary of the DOE CSGF, we've included their answers here as a bonus episode. We hope their insights will help other researchers deepen their careers. You’ll meet: : Assistant Professor of Physics at the : Senior Product Manager, : Senior Member of Technical Staff, : Senior Quantum Applications Architect, ...
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Quantum computing involves collaboration and interdisciplinarity, the meeting of minds from different perspectives to solve problems where their expertise overlaps. This episode does a version of that with audio, bringing together insider insights from four quantum researchers across industry, academia and the national labs. They discuss research areas including fundamental quantum mechanics, algorithms and calibration and the human and network connections that will be needed to build utility-scale quantum computers. All four guests are alumni of the program, which supports this podcast....
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NVIDIA is known for its AI work, and in quantum computing the company focuses on integrating quantum processors with classical processors to accelerate quantum computing. In this conversation NVIDIA's Sam Stanwyck talks about the challenge and importance of quantum error correction, the company's work on integrating quantum and classical hardware and the partnerships with startup companies and the national laboratories that propel this research forward. You'll meet: is the Director for Quantum Product at NVIDIA. He previously worked in quantum engineering at Rigetti Computing. He completed a...
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Quantum computing comes with a new layer of concepts. Quantum bits are called qubits, but there's more. Physical qubits are often grouped to form logical qubits. In our recent conversation with Jarrod McClean, we discussed logical qubits. And we're sharing that discussion as a Science in Parallel short.
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In our seventh season, we’re putting a spotlight on quantum computing, technology that could help speed up high-performance computing and artificial intelligence, shore up cybersecurity, study complex natural systems and much more. Jarrod McClean works on quantum algorithms and applications at the Google Quantum Artificial Intelligence laboratory, and this conversation links some of the ideas about AI for science from our last season to emerging quantum technology. Join us for a conversation about Jarrod's work at Google, where he thinks quantum computing could soon enter the computational...
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Computational science requires translation, breaking ideas and principles into pieces that algorithms can parse. The work requires experts capable of zooming in on core computer science while also being able to step back and make sure that the big scientific questions are addressed. This guest, Sunita Chandrasekaran of the University of Delaware, moves seamlessly across these layers— from working with students and postdocs on fundamental software, collaborating with researchers on questions ranging from physics to art conservation and helping to shape AI policy in her state. In our...
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Nearly a decade ago, the U.S Department of Veterans Affairs and the Department of Energy launched the MVP-CHAMPION initiative, not for sports, but as a data-driven strategy for improving healthcare outcomes for veterans and others. Silvia Crivelli of Lawrence Berkeley National Laboratory turned her skills in computational biology toward this new field, especially the problem of identifying veterans at high risk for suicide. As she and her colleagues worked on this challenge, large language models and the notion of foundation models emerged. Now her team is focused on a more comprehensive...
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Foundation models-- LLMs or LLM-like tools-- are a compelling idea for advancing scientific discovery and democratizing computational science. But there's a big gap between these lofty ideas and the trustworthiness of current models. Youngsoo Choi of Lawrence Livermore National Laboratory and his colleagues are thinking about to how to close this chasm. They're engaging with questions such as: What are the essential characteristics that define a foundation model? And how do we make sure that scientists can rely on their results? In this conversation we discuss a position paper that Youngsoo...
info_outlineDuke University associate professor Amanda Randles' work to simulate and understand human blood flow and its implications demonstrates how high-performance computing paired with scientific principles can help improve human health. In this conversation, she talks about how she brought together early interests in physics, coding, biomedicine and even political science and policy and followed her enthusiasm for the Human Genome Project. She discusses how supercomputers are pushing the boundaries of what researchers can learn about the circulatory system noninvasively and how that knowledge, paired with data from wearable devices, could lead to new ways to monitor and treat patients. She also talks about her public engagement and science policy work and its importance, both for educating patients and supporting computational science’s future.
You’ll meet:
Amanda Randles is the Alfred Winborne and Victoria Stover Mordecai associate professor of biomedical sciences at Duke University and director of Duke’s Center for Computational and Digital Health Innovation. Her research using high-performance computing to model the fluid dynamics of blood flow has garnered numerous awards including one of the inaugural Sony Women in Technology Awards with Nature , the 2024 ISC Jack Dongarra Early Career Award and the 2023 ACM Prize in Computing. Amanda completed her Ph.D. at Harvard University working with Efthimios Kaxiras and Hanspeter Pfister. She was a Department of Energy Computational Science Graduate Fellowship (DOE CSGF) recipient from 2010 to 2013 and a Lawrence Fellow at Lawrence Livermore National Laboratory from 2013 to 2015.
Follow Amanda on social media: LinkedIn, BlueSky and Instagram.