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SIO515: A Vast, Global Network! ... of 3 Guys

Serious Inquiries Only

Release Date: 05/18/2026

SIO526: Why Is College So Expensive? show art SIO526: Why Is College So Expensive?

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David O'Brien, higher education policy scholar with the California Community Colleges System, is back to answer the question Thomas posed last time: why is college so expensive? They get into tuition vs. total cost of attendance, the dirty little secret of private university pricing, administrative bloat, the amenities arms race, and why the people loudest about college costs are likely well-off, but getting very little financial aid. Mentioned: Are you an expert in something and want to be on the show? ! Please support the show on Patreon! You get ad-free episodes, early...

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Some More News Is COMPLETELY WRONG About Spider-Man Brand New Day show art Some More News Is COMPLETELY WRONG About Spider-Man Brand New Day

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I cannot stop thinking about Cody from Some More News's video in which he could not stop thinking about Spider-Man: Brand New Day. Cody is INCREDIBLY sure that you're an idiot incapable of watching movies or consuming art if you don't agree with his conception of what the ending of Brand New Day meant. The problem is... Cody gets about a billion things wrong and his arguments are terrible. This was going to be just a Patreon bonus of Serious Inquiries Only but I wanted to put it up on YouTube so it's going out to everyone! Are you an expert in something and want to be on the...

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SIO525: Dude Who Said Autism Is SIO525: Dude Who Said Autism Is "Extreme Male Brain" Walks It Back

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... and other autism/ADHD research! So pleased to have Dr. Jenessa Seymour back - this time with a variety of studies in the Autism and ADHD realms. Jurek, L., Duchier, A., Gauld, C., Henault, L., Giroudon, C., Fourneret, P., … Nourredine, M. (2025). . Journal of the American Academy of Child & Adolescent Psychiatry, 64, 1132-1147. Le Cunff, A., Russell, C. & Dommett, E.J. (2026). . BMC Psychology, 14, 1-11. White, R.C. & Remington, A. (2018). . Autism, 23, 1042-1045. Botha, M. & Cage, E. (2022). . Frontiers in Psychology, 13, 1-22. Devlin, H. (July 5, 2026). ....

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SIO524: Why We Haven't Cured Cancer Yet, Part 2 (with Dr. Eric Jaffe) show art SIO524: Why We Haven't Cured Cancer Yet, Part 2 (with Dr. Eric Jaffe)

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Part 2! Dr. Eric Jaffe returns to actually treat the cancer this time: why radiation is basically catching your kid smoking and making him finish the carton, how CRISPR turns your own T cells into an assassin squad, and why oncolytic viruses are just Jurassic World Dominion for tumors. Haven't heard Part 1 yet? Start there or you'll be lost. Mentioned: Are you an expert in something and want to be on the show? ! Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content!

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SIO523: What Cancer Actually Is, Part 1 (with Dr. Eric Jaffe) show art SIO523: What Cancer Actually Is, Part 1 (with Dr. Eric Jaffe)

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Part 1! Dr. Eric Jaffe, the biology teacher who keeps naming proteins after cartoon characters, returns for a two-part cancer deep dive. Today: what cancer actually is at the cellular level, why elephants barely get it, why whales get it even less, and why the "they're hiding the cure" conspiracy falls apart the second you learn who actually funds the research. Mentioned: Part 2, the cure, is already up for Patreon supporters! Are you an expert in something and want to be on the show? ! Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus...

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SIO522: College Is Impossibly Expensive. But It's Not Because of Bogus Degrees. show art SIO522: College Is Impossibly Expensive. But It's Not Because of Bogus Degrees.

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Part 2! Thomas is joined again by David O'Brien, a higher education policy scholar with the California Community Colleges system, to finish dismantling The Daily's take on Trump's student loan crackdown. Reagan, Pell Grants, and decades of quiet state defunding all get their due, plus a theory on why tuition keeps climbing that has nothing to do with cosmetology degrees. Mentioned: Are you an expert in something and want to be on the show? ! Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content!

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SIO521: The Daily Is Sane-Washing Trump's War on Higher Ed show art SIO521: The Daily Is Sane-Washing Trump's War on Higher Ed

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Thomas is joined by David O'Brien, a higher education policy scholar who works for the California Community Colleges system, to pick apart Trump's new rules threatening to cut off student loans and Pell grants from "low-earning" degree programs, and to fact-check The Daily's recent take on the same story. The real history runs through Reagan, Prop 13, and decades of quiet austerity nobody on that podcast wants to mention. Mentioned: Are you an expert in something and want to be on the show? ! Please support the show on Patreon! You get ad-free episodes, early episodes, and...

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SIO520: My Talk at SkeptiCal - Selective Skepticism Is Not Skepticism show art SIO520: My Talk at SkeptiCal - Selective Skepticism Is Not Skepticism

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Thanks so much to the folks at SkeptiCal for inviting me! Though the talk does deal with the Butler shooting, I thought some way different stuff for this including a ridiculously overwrought hypothetical, my favorite kind! And, I found a Young Turks video where they are apparently Joe Rogan now!

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SIO519: People Are Misinterpreting Obsession in Very Revealing Ways show art SIO519: People Are Misinterpreting Obsession in Very Revealing Ways

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The "nice guy" is the villain. We watched Obsession and cannot stop thinking about it. It has so much to say about gender, consent, "nice guys" and more. And it scarred Lydia for life. WARNING: CONTAINS SPOILERS. Are you an expert in something and want to be on the show? ! Please support the show on Patreon! You get ad-free episodes, early episodes, and other bonus content!

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SIO518: Biological Definitions Do Not Do What Richard Dawkins Says They Do show art SIO518: Biological Definitions Do Not Do What Richard Dawkins Says They Do

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Thomas is joined by Dr. Eric Jaffe, biologist, dinosaur enthusiast, and high school biology teacher, for a conversation that starts with a deceptively simple question: what are biological definitions actually doing? It turns out that biology is far more like history than math, and that difference has enormous consequences for anyone trying to weaponize phrases like "the biological definition of sex." Dr. Jaffe walks through why definitions in inductive sciences are descriptive, not prescriptive, and what that means for species, chromosomes, fungi, LeBron James, and trans people. "Exceptions...

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More Episodes

Continuing the discussion of the CNN Rape Academy article. It gets even worse. And also, how our information environment is ruined and getting ruineder.