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LGTBQI Health-related Issues Part 1

seX & whY

Release Date: 01/31/2020

Sex and Gender Differences in Aging show art Sex and Gender Differences in Aging

seX & whY

Show Notes for Episode Twenty-Six of seX & whY: Sex and Gender Differences in Aging Host: Jeannette Wolfe Guest: Dr Haag is a researcher in molecular epidemiology who studies human biological aging at the Karolinska Institute in Stockholm. Background - Dr Haag has a PhD in functional genomics and Post Doc in genetic and molecular epidemiology. She studies telomeres and molecular association with telomere length, she also has experience in molecular biology and computer science. Definitions and discussion points from podcast - a new field of biomedical science that looks at how the...

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Global Health and Pandemic Responsiveness Through a Sex and Gender Lens Part 2 show art Global Health and Pandemic Responsiveness Through a Sex and Gender Lens Part 2

seX & whY

Show Notes for Episode Twenty-Five of seX & whY, Part 2: Global Health and Pandemic Responsiveness Through a Sex and Gender Lens Host: Jeannette Wolfe Guests: McKinzie Gales and Emelie Yonally Phillips  – Global Health Fellow at the CDC and co-lead for Phase I of the multi-agency SAGER IOA project aimed at facilitating better collection, analysis, and use of sex-disaggregated data and gendered data for outbreak response.    – Global Health consultant (Epicentre/MSF) and core member of the Integrated Outbreak Analytics initiative ...

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Global Health and Pandemic Responsiveness Through a Sex and Gender Lens Part 1 show art Global Health and Pandemic Responsiveness Through a Sex and Gender Lens Part 1

seX & whY

Show Notes for Episode Twenty-Five of seX & whY: Global Health and Pandemic Responsiveness Through a Sex and Gender Lens Host: Jeannette Wolfe Guests:  – Fellow at the CDC and co-lead for Phase I of the multi-agency SAGER IOA project aimed at facilities' better collection, analysis, and use of sex-disaggregated data and gendered data for outbreak response.  – Global Health consultant and core member of the Integrated Outbreak Analytics initiative   Definitions IOA - Integrated Outbreak Analytics SAGER - Sex and Gender Equity in Research  The Integrated Outbreak...

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Sex and Gender Differences in Conflict - Part 2 show art Sex and Gender Differences in Conflict - Part 2

seX & whY

Show Notes for Episode Twenty-Four of seX & whY: Sex and Gender Differences in Conflict, Part 2 Host: Jeannette Wolfe Guest: Joyce Benenson, lecturer of evolutionary biology at Harvard and author of the book In this podcast we continue our discussion about women interacting with each other at the workplace and how women often manage hierarchy differently than men. We got into a spirited discussion about a question posted on a female physician’s list serve querying whether women physicians want to be addressed as  “Doctor” by other staff members. (My own preference was “yes” in...

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Sex and Gender Differences in Conflict - Part 1 show art Sex and Gender Differences in Conflict - Part 1

seX & whY

Show Notes for Episode Twenty-Four of seX & whY: Sex and Gender Differences in Conflict, Part 1 Host: Jeannette Wolfe Guest: Joyce Benenson, lecturer of evolutionary biology at Harvard and author of the book Warriors and Worriers Here is a link to Dr Benenson’s book .  This book dives deep into the evolutionary roots of human behavior and Dr Benenson makes a very clear and well referenced case that human males and females have evolved from slightly different playbooks.  The root of this difference is sexual selection in that adaptions and behaviors that optimize the chance...

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Issues Surrounding Men’s Health - Part 2 show art Issues Surrounding Men’s Health - Part 2

seX & whY

Show Notes for Episode Twenty-Three of seX & whY: Issues Surrounding Men’s Health, Part 2 Host: Jeannette Wolfe Guests: Peter Baker –   Twitter: Dominick Shattuck has a PhD in psychology and does Global Health Work at Johns Hopkins Bloomberg School of Public Health              Main topics discussed: Challenges and barriers associated with optimizing men’s mental health and the role of men in reproductive health-related issues. Men’s mental health is important not just for men but for the health of communities....

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Issues Surrounding Men’s Health - Part 1 show art Issues Surrounding Men’s Health - Part 1

seX & whY

Show Notes for Episode Twenty-Three of seX & whY: Issues Surrounding Men’s Health, Part 1 Host: Jeannette Wolfe Guests: Peter Baker –   Twitter: Dominick Shattuck has a PhD in psychology and does Global Health Work at Johns Hopkins Bloomberg School of Public Health              Here is a  of Peter Baker’s publications including  Here is a  of Dominick Shattuck’s publications Take home points Somewhat ironically even though most major health related organizations are dominated by men in...

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Sex, Drugs, and Rats show art Sex, Drugs, and Rats

seX & whY

Show Notes for Episode Twenty-Two of seX & whY: Sex, Drugs, and Rats Host: Jeannette Wolfe Guest: Dr Irv Zucker, Faculty at UC Berkley since 1966. Interests include behavioral endocrinology, chronobiology, and sex differences in pharmacology General discussion Many times, the worlds of basic science and human clinical trials do not overlap to the degree that they should. Greater coordination between the two silos, especially as it comes to the examination of sex differences, would likely produce more robust, higher quality science that would benefit a greater number of...

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Sex and Gender Differences in Opioid Use Disorder show art Sex and Gender Differences in Opioid Use Disorder

seX & whY

Show Notes for Episode Twenty-One of seX & whY: Opioid Use Disorder Host: Jeannette Wolfe Guests: Dr Alyson McGregor, author of Sex Matters: How Male-Centric Medicine Endangers Women's Health and What We Can Do About It Dr Lauren Walter Here is link to American Psychiatric Association DSM 5 diagnosis for opioid use disorder from the . Essentially the disorder is defined by continued craving and use of opioids despite significant social and professional consequences caused by its use. This podcast is on sex and gender differences in opioid use disorder. Although sex (s) and gender (g) are...

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Interview With Dr Shirin Heidari Part 2: Gendro - Advancing Sex and Gender Equity in Science Research show art Interview With Dr Shirin Heidari Part 2: Gendro - Advancing Sex and Gender Equity in Science Research

seX & whY

Show Notes for Episode Twenty of seX & whY: Interview With Dr Shirin Heidari Part 2: Gendro - Advancing Sex and Gender Equity in Science Research Host: Jeannette Wolfe Guest: Shirin Heidari PhD, virologist and experimental oncologist, founding President of Gendro. Part 2 of Interview with Dr Shirin Heidari This podcast focuses on Dr Heidari’s work on systematically integrating the variables of sex and gender into different access points along the research pipeline. She helped start an organization called  which is dedicated to this mission.  The three major gatekeeping posts...

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More Episodes

Show Notes for Episode Thirteen of seX & whY: LGTBQI Health-related Issues Part 1

Host: Jeannette Wolfe
Guests: 

  • Dr Elizabeth Samuels Assistant Professor of Emergency Medicine Warren Alpert School of Medicine at Brown University
  • Dr Michelle Forcier
  • Professor of Pediatrics at Warren Alpert School of Medicine at Brown University and Director of Gender and Sexual Health Services 

This is the first of a three-part series that will cover LGTBQI health related issues. This podcast focuses on some basic definitions and general principles surrounding the care of gender non-conforming children and adolescents. It also discusses some of the gender affirming hormonal and surgical options available to patients. 

Resources that we discussed

The link to USCF’s Center of Excellence for Transgender Health

The link to the American Academy of Pediatrics statement on transgender and gender diverse children.

The link to the Gender Unicorn  

Basic definitions

Biological Sex 

  • This is related to our innate sex chromosomes and hormones

Gender 

  • Influenced by biological sex and sociocultural constructs

Gender Identity

  • How an individual internally perceives themselves within the norms and expectations of society in which they live

Gender Expression

  • How an individual presents their gender publicly via mannerisms, appearance and clothing, etc

Gender Asserting

  • How an individual perceives themselves and desires to be viewed by the world 

Gender Affirming

  • Hormones, procedures or clothing that align with asserted gender

Gender Dysphoria

  • The distress a person may experience when their gender identity is not aligned with their assigned sex

Hormones commonly used

  • To stall puberty
    • Gonadotropin-releasing hormone (GnRH) analogues
  • Transmen
    • Testosterone
  • Transwomen 
    • Estradiol (and possible spironolactone or finasteride)

Gender affirming surgeries

Transwomen

  • breast augmentation
  • orchiectomy
  • feminizing vaginoplasty
  • reduction thyrochondroplasty
  • voice surgery

Transmen

  • hysterectomy
  • oophorectomy
  • vaginectomy
  • metoidioplasty (clitoral release and enlargement)
  • phalloplasty/scrotoplasty
  • masculinizing chest surgery (“top surgery”)

Gender non-conforming health related issues that can occur in transgender and gender non-conforming patients

  • Tucking of scrotum and penis that can lead to trauma/inflammation, infection, reflux
  • Estradiol related thrombosis
  • Testosterone related uterine bleeding
  • Infection or emboli from body sculpting injections 

Take home points

  • When someone identifies themselves as transgender that simple means that their gender identity does not align with their assigned sex. It doesn’t mean that they have necessarily had specific surgeries or that they are taking certain hormones.
  • Gender identity is distinct from an individual’s sexual preference. 
  • Some younger kids can experience their gender identity in a more fluid manner. This can often make it more difficult to predict what their gender identities will be later on as adults. Supporting and respecting these kids for where they are, and understanding that their gender identity may or may not later change, is important for their social and psychological development. 
  • As kids reach puberty their gender identity is generally less fluid and more permanent, for kids and their families who our struggling with gender identity, puberty blockers are an option to give people more time to process information and make decisions 
  • Currently there are multiple gender affirming treatments available to trans-individuals, including hormonal treatments and different types of surgeries some of which may become important when a transgender individual becomes a patient in our emergency department

Next month we will focus on how we can deliver better care to transgender and gender non-conforming patients in our emergency departments.