The Next Frontier: Autonomous Security and RSAC Interviews from Quantro & SandboxAQ - Marc Manzano, Mark Hughes, Mehul Revankar - BSW #445
Business Security Weekly (Audio)
Release Date: 04/29/2026
Business Security Weekly (Audio)
Artificial intelligence has quickly evolved from a productivity tool into an active participant in many organizations' daily operations. As organizations give AI greater autonomy within their environment, they're also granting them access to sensitive systems and data. That creates a new challenge for IT and security teams: How do you enable AI to assist productivity without compromising security? Rob Allen, Chief Product Officer at ThreatLocker, joins Business Security Weekly to discuss how zero trust principles can prevent an AI breakout. Rather than relying solely on the AI tool's built-in...
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As cyber threats become more AI-powered, attacks continue to rise. Threats can arise from all areas of a company’s IT infrastructure, however most attacks utilize a domain name to infiltrate systems. How secure is your domain ecosystem? Ihab Shraim, Chief Technology Offider at CSC Digital Brand Services, joins Business Security Weekly to discuss why domain security is a fundamental blind spot in corporate cybersecurity programs. Ihab will discuss his team’s research finding that 67% of Forbes Global 2000 companies have implemented fewer than half of recommended domain security measures. He...
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This week, we air our thirteenth pre-recorded segment called “Say Easy, Do Hard”. Inspired by my co-host, Jason Albuquerque, we discuss “Performance Through People”. Greg Hoffman joined us a few weeks back to discuss his new book. This week, we dig into his five disciplines of Performance Through People and do the hard part. Visit for all the latest episodes! Show Notes:
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Since the pandemic, managing remote teams have been challenging. How do you measure performance and motivate teams when they are remote? Charles Gaudet, CEO & Founder at Predictable Profits, joins Business Security Weekly to discuss why transparency is the key to team motivation for remote workers. Charles will discuss how culture and performance metrics create that transparency. He will also discuss how to motivate your team based on their personality type. Segment 1 Resources: Find all of CyberRisk TV's Black Hat 2026 coverage at: Visit for all the latest episodes! Show Notes:
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America has lived through technological and economic upheaval before. Farm workers moved to factories. Factory workers moved into services. New industries replaced old ones. Productivity rose. Living standards improved. But are we ready for the greatest disruption in American history? Ben Gilliland, author of the upcoming book Breaking the Compact, joins Business Security Weekly to discuss why business leaders need to be prepared for the upcoming AI disruption. The impact of AI, which has not fully materialized, goes far beyond security and job displacement. It will impact our economy, our...
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More than 48,000 vulnerabilities were disclosed in 2025, yet only about 1% are actively exploited. However, you’re expected to mitigate all vulnerabilities, or at least critical and high. But what if there is no patch to fix the vulnerability or the software is unsupported? Ben Lipcynski, Director Security and Regulatory Services at Optima, joins Business Security Weekly to discuss how organizations can take back control of your enterprise software. OPTAS — Origina Proactive Threat Assurance Service — predicts, validates, prioritizes, and mitigates threats specific to your environment....
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The latest generation of AI models has collapsed the time from vulnerability discovery to weaponized exploit from weeks to minutes, and reactive, module-based tools built around static dashboards simply can't keep up. In this episode, Tanium COO Matt Quinn joins Business Security Weekly to discuss Tanium Atlas, the new autonomous operating system for IT and security. Matt explains why "good enough" operations are now a liability, how Atlas turns a single operator into the equivalent of an entire team, giving organizations the speed, scale, and efficiency to match the pace of today's threat...
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One of the biggest questions most executives ask is "Why does it still feel this hard when the talent is clearly there?" The answer, in almost every case, is not a people problem. It is an environment problem. And environment is something a leader can build. Greg Hoffman, President at Ascension Performance Group, joins Business Security Weekly to discuss his new book, Performance Through People, a leadership parable that shows a practical operating model for building the conditions where people perform at their highest level. It is written as a story, but it is built as a framework. Greg will...
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The 2026 Verizon DBIR has arrived and the results are in... Even with a substantial increase in Exploitation of Vulnerabilities, All Credential Abuse is still the top initial access vector for breaches, which means the human is still the weakest link. Why haven't security awareness training and phishing campaigns worked? Robert Siciliano, Architect of of The Strategic Human Firewall™ at ProtectNow, joins Business Security Weekly to explore why humans, not hackers, are the ultimate deciding factor in organizational security. The industry needs to shift from security awareness to security...
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The browser has become the primary gateway to work, data, and AI. In this episode, Arunesh Chandra, Head of Product, Microsoft Edge for Business at Microsoft Edges for Business, will discuss why security and IT teams are rethinking the role of the browser and what sets Edge for Business apart as a secure, enterprise-ready solution. Arunesh cover how built-in security, native integration with existing IT tools, and centralized management can simplify operations, reduce risk, and support modern work across managed devices, BYOD, and contractors. A must listen for IT pros and security experts...
info_outlineAttackers are increasingly weaponizing frontier models to accelerate the entire attack lifecycle, with current and emerging models reducing the time and expertise needed to start disruptive attacks. As offensive capabilities become more automated and agentic, organizations will need security programs that are equally autonomous, coordinated and continuous. But where do you start?
Mark Hughes, Global Managing Partner, Cybersecurity Services at IBM, joins Business Security Weekly to discuss autonomous security, the next frontier of cybersecurity services. IBM recently announced IBM Autonomous Security, a separate service that uses AI agents to analyze software exposures and runtime environments. Mark will discuss the fears and hype of AI and how agentic AI agents can identify paths in an enterprise security environment that can be exploited, improve cyber hygiene, and enforce security policies. As frontier models, like Mythos, accelerate attacks, security programs need to respond with speed, at scale, to drive the right business outcomes.
AI Agents for Vulnerability Management Introducing Quantro Security, Inc., a new agentic AI solution bringing AI agents to vulnerability management. The company is focused on applying agentic AI to help address modern security challenges. In this interview, we’ll learn more about Quantro Security, Inc., its approach, and what this new solution means for the future of vulnerability management.
This segment is sponsored by Quantro Security. Visit https://securityweekly.com/quantrorsac to learn more about them!
The Guardrails are Gone: The Onus for AI Security Is On the Enterprise AI model providers are increasingly stepping back from enforcing guardrails, putting the responsibility for AI security squarely on enterprises. But most organizations don't yet have the visibility to meet that responsibility, facing a blind spot across the broader ecosystem of AI systems already operating in their environments. Closing that gap requires unified visibility across both AI systems and the cryptographic infrastructure they touch, so security teams can assess risk and act on it in one place.
Visit https://securityweekly.com/sandboxaqrsac to discover how enterprises are taking control of their AI security with AQtive Guard AI-SPM by SandboxAQ.
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Show Notes: https://securityweekly.com/bsw-445