🎙️ This Week in San Diego Tech (4/21/25 Edition)
Release Date: 04/21/2025
Tacos and Tech Podcast
In this episode of the Tacos & Tech Podcast, host Neal Bloom sits down with , founder of ShredLights and now part of Meepo Electric Skateboards. Eric’s story is a wild ride - from 3D-printing in the SDSU ZIP Launchpad and selling Jordans out of thrift stores, to building a niche hardware company and ultimately exiting to a global electric skateboard brand. They unpack how Eric turned an early failed Kickstarter into a business with over $1M+ in revenue (with zero ad spend!), the importance of discovering product-market fit through real customer feedback, and the emotional rollercoaster...
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This week on Tacos & Tech, Neal sits down with Drew Wilson, longtime North County founder, designer, engineer, and community builder. From launching products solo to landing a GoDaddy acquisition, Drew’s track record speaks for itself. Now he’s back with a new company, Opacity, and relaunching his beloved creative conference, ValioCon, right in the heart of Oceanside. In this episode, Drew shares his journey from early design days and Flash websites to building Plasso, navigating acquisition, and diving headfirst into GenAI-powered product development. He also gives us...
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Listen & subscribe on , , , and Welcome everyone to the weekly San Diego Tech News! I’m from , building and investing in community. My co-host in this episode is , journalist and author of substack. He covers the ins-and-outs of the startup world including breaking news, IPOs, fundraising rounds, and M&A through his newsletter. Before we dive in, we wanted to thank and ask our listeners to help us grow the show, leave a review and share with one other person who should be more plugged in with the SD Tech Scene. Thank you for the support and for helping us build the San Diego...
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In this episode of the Tacos & Tech Podcast, Neal Bloom sits down with former Olympian, Navy SEAL, and now Managing Partner of Harpoon Ventures, an early-stage venture firm backing founders building in the national interest. Larsen shares the journey from serving Team USA to launching a venture fund focused on what he calls the Freedom Stack - critical technologies like AI, autonomy, cybersecurity, and advanced manufacturing that shape not just industry, but national security and global stability. They explore how Harpoon was early to the intersection of tech and geopolitics, why San...
info_outlineTacos and Tech Podcast
Listen & subscribe on , , , and Welcome everyone to the weekly San Diego Tech News! I’m from and the . My co-host in this episode is , journalist and author of substack. He covers the ins-and-outs of the startup world including breaking news, IPOs, fundraising rounds, and M&A through his newsletter. Before we dive in, we wanted to thank and ask our listeners to help us grow the show, leave a review and share with one other person who should be more plugged in with the SD Tech Scene. Thank you for the support and for helping us build the San Diego Startup Community! Aug 15 ...
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In this episode of the Tacos & Tech Podcast, Neal Bloom sits down with Madeline Fraser, the dynamic founder and CEO of Gemist, a B2B SaaS and AI company revolutionizing the jewelry industry. Madeline shares how a frustrating search for a custom engagement ring sparked the idea for Gemist, which now powers customization, stone sourcing, and hyper-realistic rendering for jewelry brands and retailers. With deep product insight and two previous startups under her belt - including an appearance on Shark Tank and an exit into the gaming space - Madeline unpacks how her creative background and...
info_outlineTacos and Tech Podcast
Listen & subscribe on , , , and Welcome everyone to the weekly San Diego Tech News! I’m from and the . My co-host in this episode is , journalist and author of substack. He covers the ins-and-outs of the startup world including breaking news, IPOs, fundraising rounds, and M&A through his newsletter. Before we dive in, we wanted to thank and ask our listeners to help us grow the show, leave a review and share with one other person who should be more plugged in with the SD Tech Scene. Thank you for the support and for helping us build the San Diego Startup Community! August 8...
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In this special episode of the podcast, host Neal Bloom takes us inside the Burbank Startup Pitch Fest - an exciting evening of innovation, capital, and community hosted in partnership with the City of Burbank and Rising Tide Partners. We kick things off with a welcome from Burbank’s Economic Development team, highlighting why the city is fast becoming a tech and media hub. Neal then moderates a candid conversation with early-stage investors Amy Harmon (Innovent Capital) and Ben Kahan (Pegasus Angel Accelerator) about today’s venture landscape - from what they look for in a pre-seed deal...
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In this episode of the Tacos & Tech Podcast, host Neal Bloom sits down with Alex Adler, co-founder of Puesto, to talk about how a family with no restaurant background built one of the most beloved modern taco brands in the country. From its La Jolla beginnings to an expanding restaurant group that includes Marisi and Romana Norte, Puesto has grown through a mix of culinary authenticity, operational innovation, and cultural conviction. Alex shares the origin story of Puesto, early pivots that reshaped their entire concept, how Toast and DoorDash changed the game for their operations, and...
info_outlineTacos and Tech Podcast
Listen & subscribe on , , , and Welcome everyone to the weekly San Diego Tech News! I’m from and the . My co-host in this episode is , journalist and author of substack. He covers the ins-and-outs of the startup world including breaking news, IPOs, fundraising rounds, and M&A through his newsletter. Before we dive in, we wanted to thank and ask our listeners to help us grow the show, leave a review and share with one other person who should be more plugged in with the SD Tech Scene. Thank you for the support and...
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đź‘‹ Welcome!
Welcome to This Week in San Diego Tech!
I’m Neal Bloom from Fresh Brewed Tech, the Tacos and Tech Podcast, and Interlock Capital.
Joining me as always is Fred Grier, journalist and author of The Business of San Diego Substack, covering startups, funding, and M&A across the region.
🗞️Top Headlines This Week:
🎶 Music Tech Meets the Symphony - link
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Interlock Capital hosted 30+ tech leaders for a behind-the-scenes tour of the newly renovated Jacobs Music Center ($150M remodel!)
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The tech community showed up at the San Diego Symphony’s Discovery Night, featuring jazz, Mardi Gras flair, and remarks by ResMed CEO Mick Farrell
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The call to action: it’s time for the next generation of founders to support arts, science, and innovation in SD
🚀 Startup 101 & Founders Funnel Kickoff - link
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Neal and Tim Ryan launched Startup 101, a community event for early-stage builders to explore the “car, plane, or rocket ship” path of growth
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10 attendees, curated cohort, high demand for more, filling a new cohort each quarter - and Founders Build Day now expanding to 3 monthly locations in May!
đź’° Funding Rounds
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Symphonic Capital raises $13.5M for its debut fund, led by Sydney Thomas (ex-Precursor), focused on fintech and digital health
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Bliss AI, an aesthetic-focused AR software platform, secures Series A funding (co-founder based in North County)
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Biolinq raises $90M for non-invasive glucose sensing — originally spun out of UCSD labs and now scaling hard
🧬 NIH Funding Shakeup & Market Headwinds - link
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UCSD sees $150M+ in NIH funding paused or cut, impacting researchers and early-stage startups
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Federal agency funding delays (FDA, DOD, SBIR) creating ripples in life sciences and defense tech
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Tariffs, market uncertainty, and reduced VC capital raise concerns for hardware and deep tech founders
đź§± Real Estate & Ecosystem Expansion
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Pfizer moves to new Torrey View campus
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Novartis to build a $1.1B San Diego R&D hub
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Prebys Foundation acquires Wells Fargo Plaza for $40M (previously $148M), signaling interest in downtown tech corridor
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GemPharmatech, Qpex, and BioLabs expanding presence in the region
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EvoNexus UTC set to open new space for medtech/life science founders in May
👟 SDSU Goes Jordan
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San Diego State men’s basketball team debuts custom Air Jordan 4 PEs — only 50 pairs made!
🗓️ Community Events & Ecosystem News
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One Million Cups is back!
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Every Wednesday at 8am @ Ansir Innovation in Convoy
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Two startup presentations + community feedback
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Interlock Capital LP + Portfolio Founder Day
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LPs and founders will be connecting in curated roundtables to move the needle on growth
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The Social Coyote has your curated event list:
đź’¬ Final Shoutouts
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Thanks to Michael Robertson and other listeners for your feedback — we’re testing a shorter intro song this week!
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Follow Fred on Substack » and Neal on Fresh Brewed Tech »