312: Cry Havoc!, and Let Slip the Phages of Healing
Release Date: 06/28/2024
This Week in Microbiology
TWiM explains how a mutualistic model bacterium can become lethal in a non-symbiotic host, and engineering a kill switch into a tuberculosis vaccine for improved safety. Hosts: , , and . Subscribe to TWiM (free) on , , , , or by Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode When a (mBio) A lasting (Nat Rev Micro) A (Nat Micro) for vaccination (Nat Micro) Send your microbiology questions and comments (email or recorded audio) to
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TWiM explains a study of the unique and extreme microbial and chemical environment on the International Space Station, and the connection between the gut microbiome and pain in fibromyalgia. Hosts: , , and . Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode (Cell) Gut microbiota and (Neuron) Gut pain eases after (Nature) and fibromyalgia pain (Ann Neurol) Altered (Pain) (Intl J Rheum Dis) Send your microbiology questions and comments (email or recorded audio) to
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TWiM describes isolation of a novel bacterial species isolated from the China Space Station, and how a chemical radar allows bacteria to detect and kill predators. Hosts: , , and Guest . Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode (Int J Syst Evol Biol) (Cell) Send your microbiology questions and comments (email or recorded audio) to
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TWiM explains how to recode E. coli so it uses only one stop codon, and an exploration of the mechanisms of bacterial adhesion within dental plaque. Hosts: , , and . Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode Engineering (Nature) (mBio) Microbial complexes in (J Clin Periodontol) (Microorg) Send your microbiology questions and comments (email or recorded audio) to
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TWiM explains Pasteur’s relentless hunt for microbes in the air, and how bacteria hunt for prey by ixotrophy - using grappling hooks! Hosts: , , and . Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode Pasteur’s hunt for (NYTimes) (Science) (STC) Send your microbiology questions and comments (email or recorded audio) to
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TWiM describes Shigella infection is facilitated by interaction of human enteric α-defensin 5 with a colonic epithelial receptor, and an amino acid change in RNA polymerase that leads to resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism Hosts: , , and . Subscribe to TWiM (free) on , , , , or by Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode National Black (CDC) (Nature Microbio) (Cell Rep) Send your microbiology questions and comments (email or recorded audio) to
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TWiM explains the remarkable abilities of bacterial ice nucleating proteins to promote freezing of water, and cryoprotective proteins produced by worm microbiomes that prevent freezing. Hosts: , , and . Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode Worm microbiomes produce (Sci Adv) in Antarctic fishes (Sciece) Enhancement of (PNAS) Send your microbiology questions and comments (email or recorded audio) to
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TWiM explores the discovery of microbial enzymes, PETases, that can degrade ubiquitous plastics, and how exogenous peptidoglycan is a danger signal to trigger biofilm formation. Hosts: , , . Guest . Subscribe to TWiM (free) on , , , , or by Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode Discovery of (Science) formation (Nat Micro) (Vimeo) (Immunol Rev) (Science) Send your microbiology questions and comments (email or recorded audio) to
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TWiM reveals that record high atmospheric methane growth has been driven by microbes, and the cecum as an adaptive niche for Salmonella typhi. Hosts: , and Michele Swanson. Subscribe to TWiM (free) on , , , , or by Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode Why a potent (WaPo) Microbial emissions drove (PNAS) in the cecum (mBio) (The Collector) Send your microbiology questions and comments (email or recorded audio) to
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From ASMCUE 2024, the conference on undergraduate education, TWiM speaks with Becky, Melanie, and Katriana about their careers and how they use TWiM in undergraduate microbiology education. Hosts: and Guests: , , and Subscribe to TWiM (free) on , , , , or by Become a of TWiM. Music used on TWiM is composed and performed by and used with permission. Links for this episode Send your microbiology questions and comments (email or recorded audio) to
info_outlineTWiM explains a new mechanism for preventing lysogeny through temperate phage-antibiotic synergy, and Salmonella expansion in the murine gut dependency on aspartate derived from reactive oxygen species-mediated microbiota lysis.
Hosts: Michael Schmidt, Petra Levin and Michele Swanson.
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Links for this episode
- Temperate phage-antibiotic synergy (mBio)
- Salmonella expansion dependent on aspartate (Cell Host Micr)
- Arrowsmith by Sinclair Lewis (Wiki)
- A Genetic Switch by Mark Ptashne
- Lysis timing and bacteriophage fitness (Genetics)
- HK97 capsid assembly (Ad Exp Med Biol)
- Mode of action of fluoroquinolones (Drugs)
- Salmonella a foodborne pathogen (CDC)
- Freeman Hrabowski Scholars Program (HHMI)
- Sam Kaplan - 30 years of Microbiology (McGovern Medical School)
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