TWiP 290: What's Biting You at Night?
This Week in Parasitism
TWiP solves the case of the patient who developed an intensely itchy, red papular rash after close contact with chickens and their bedding, where small mites were found. Hosts: , , and Subscribe (free): , , , Links for this episode Join the MicrobeTV Hero of the Month: Ogobara Doumbo (, , ) on TWiP 290 New Case Man in 30s with well controlled diabetes, elevated AST ALT liver tests, asymptomatic. Ultrasound of liver, multiple cysts. Born in rural Yemen, grew up on farm with cattle, sheep, donkeys, 3-4 indoor/outdoor dogs, bathroom inside house, frequently swam in fresh...
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TWiP 289: Dogs, Parasites, and an Exhausted Immune System
This Week in Parasitism
TWiP explains a single-cell analysis of immune cells in the blood of dogs with canine leishmaniosis, providing a detailed picture of how the immune response changes as the disease progresses. Hosts: , , and Subscribe (free): , , Links for this episode Join the MicrobeTV Single immune cell atlas of (iScience) in CanL (LeishVet) Become a of TWiP Send your questions and comments to Music by
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TWiP 288: Taco Bell and the Case of the Runny Jobbies
This Week in Parasitism
TWiP solves the case of the NYC woman in her 30s who developed 3 weeks of significant watery diarrhea after eating at a Taco Bell Restaurant. Hosts: , , and Subscribe (free): , , , Links for this episode Join the MicrobeTV on TWiP 288 Parasite of the month – Parelaphostrongylus tenuis — meningeal worm (brainworm) entry P. tenuis in (Food Animal Pract) P. tenuis in (Int J Parasitol Parasites and Wildlife) New Case Early teen, otherwise healthy, develops rash, for a few weeks, problem at night. All over the body. Helps with backyard chicken coop, plays with...
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TWiP 287: A Vaccine Against Schistosomiasis? SchistoShield Heads to Phase 2
This Week in Parasitism
Mumtaz Balkhi joins TWiP to discuss phase 1 and 1b trials of the schistosomiasis vaccine SchistoShield which demonstrate that it induces functional immune memory responses in US and African populations. Hosts: , , and Guest: Subscribe (free): , , , Links for this episode Join the MicrobeTV Phase 1 and 1b results (npj Vaccines) Become a of TWiP Send your questions and comments to Music by
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TWiP 286: Pinworms keep coming back! How to stop reinfection in your home
This Week in Parasitism
TWiP solves the case of the adult female with a 2 year old child who develops anal irritation, but the child and the husband are fine. Hosts: , , and Subscribe (free): , , , Links for this episode Join the MicrobeTV on TWiP 286 Hero – New Case Recent case. Woman in 20s, lives in NYC, goes to urgent care with 3 weeks of significant watery diarrhea, not improving. Otherwise healthy, no travel, works in office in NYC, at some point prior to onset she ate at a Taco Bell. Put on twice a day medication, molecular test of stool confirms...
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TWiP 285: Why Is Cyclospora So Hard to Contain? Parasitologists Explain the 2026 US Outbreak
This Week in Parasitism
TWiP reviews our current understanding of the biology of Cyclospora, the parasite currently causing a large multistate outbreak in the US traced to contaminated lettuce, and why it is so difficult to control. Hosts: and Christina Naula Subscribe (free): , , , Links for this episode Join the MicrobeTV of Cyclospora cayetanensis (Comp Rev Food Sci Food Safety) Become a of TWiP Send your questions and comments to Music by
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TWiP 284: It's not the pork
This Week in Parasitism
TWiP solves the case of the 39-year-old man originally from Guatemala, who moved to one of the NYC boroughs in 2023 and presented with headaches for nearly 1 year. Hosts: , , and Christina Naula Subscribe (free): , , , Links for this episode Join the MicrobeTV on TWiP 284 New Case Recent ID consult: MD/PhD mother doing research, married with child 2 yo, female develops anal irritation, husband is fine, child is fine. Parasitic etiology is considered. Referred to academic ID providers, turns out she had this etiology considered, had received some...
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TWiP 283: Warming up to cryptosporidiosis
This Week in Parasitism
TWiP reviews the projected impact of climate change on the burden of Cryptosporidium in Mali, Kenya, and The Gambia. Hosts: and Christina Naula Subscribe (free): , , , Links for this episode Join the MicrobeTV on Cryptosporidium (J Inf Dis) on TWiP 283 Become a of TWiP Send your questions and comments to Music by
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TWiP 282: Does he live in New York?
This Week in Parasitism
TWiP solves the case of the nonbinary patient in his 30s with a history HIV/AIDS presenting with 3 weeks of subjective fevers, chills, generalized weakness and voluminous ostomy output. Hosts: , , and Christina Naula Subscribe (free): , , , Links for this episode Join the MicrobeTV Parasite of the Month: (the green-banded broodsac) on TWiP 282 New Case 39-year-old man originally from Guatemala, who moved to one of the NYC boroughs in 2023 and currently lives with his siblings and cousins, presented with headaches. He reports headaches for several...
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TWiP 281: Ants under the influence
This Week in Parasitism
TWiP reviews gene expression in wood ants infected with the larval lancet fluke, which causes them to leave their nest and attach to a flower until they are eaten by a grazing mammal. Hosts: , , and Christina Naula Subscribe (free): , , , Links for this episode Join the MicrobeTV Gene expression in wood ants (Mol Ecol) Visualisation of the master manipulator in the (Sci Rep) Become a of TWiP Send your questions and comments to Music by
info_outlineTWiP solves the case about the female who traveled to Brazil and upon returning home felt movements under her scalp on the back of her head, and present another case for your solving, a man with abnormal brain MRI.
Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula
Guest: Eyal Leshem
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Links for this episode
- Join the MicrobeTV Discord server
- Life cycle of Dermatobia hominis (CDC)
- Letters read on TWiP 267
- TWiP study - information and survey
New Case
Man in his 40s, married with 2 children, on Eliquis for a prior DVT, diet-controlled diabetes, who is admitted for evaluation of an abnormal brain MRI. He left AMA but then developed vomiting and returned.
CT- Large peripherally enhancing mass lesion in the deep left cerebral hemisphere is associated with considerable vasogenic edema/infiltrative nonenhancing tumor. Mass effect results in left-to-right subfalcine herniation and entrapment of the right lateral ventricle. Findings are typical for glioblastoma. Intracranial abscess tumefactive multiple sclerosis and brain metastasis may mimic this appearance. Recommend supplemental imaging evaluation including gadolinium-enhanced MR brain.
MRI- Dominant heterogeneously enhancing mass in the left basal ganglia/peri-insular region measuring 3.1 cm AP by 2.8 cm TR by 2.9 cm cc, with surrounding vasogenic edema resulting in mass effect and midline shift, as detailed above, concerning for high grade glial neoplasm versus metastasis. Additional leptomeningeal nodule in the right postcentral sulcus. Additional smaller peripherally enhancing lesion in the right lateral temporal region with suggestion of leptomeningeal component and measures approximately 0.8 x 0.8 cm, with mild surrounding vasogenic edema.
They do a biopsy and pathology comes back as: – Brain tissue with extensive necrosis acute chronic inflammation, and rare microorganisms (on permanent section)
-Brain, designated “left brain lesion”, excision:
– Brain tissue with extensive necrosis acute and chronic inflammation, reactive gliosis and occasional microorganisms
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