This Week in Virology
TWiV discusses the latest worrisome Executive Order on oversight of federal grantmaking, RFK Jr winds down mRNA viral vaccine development, Lenacapavir, a drug for AIDS prevention and treatment, and how respiratory virus infections awaken dormant metastatic breast cancer cells in lungs. Hosts: , , and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Oversight of (Whitehouse.gov) gets a Christofascist (Rasmussen Retorts) HHS winds down (HHS) by COVID vaccines (JAMA) review...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello re-address the dangers of drinking raw milk, the Legionnaire’s outbreak in Harlem and results of a vaccine knowledge survey done by emergency departments before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, reports of influenza-associated acute necrotizing encephalopathy or neuropsychiatric events in children, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Pfizer and MODERNA vaccines against the JN.1...
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TWiV reports the administration putting a choke hold on billions of NIH health research funding, US Senators tell scientists they want to protect the NIH budget, then review a classic experiment showing the mechanism of DNA replication, and explain how jumbo phage DNA is transcribed in a membrane-bound compartment before transfer into proteinaceous “nucleus” compartment. Hosts: , , , , , and Angela Mingarelli Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV 5:13 Chokehold on billions in (WSJ)...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the recent Salmonella typhimurim outbreak, the ousting of another CBER director, confirmation of a new CDC director and results of a recent pool about vaccine safety and trust before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, a new anti-influenza antibody that can be combined with neuraminidase inhibitors, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Sinopharm’s COVID-19 vaccine, where...
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TWiV explains a cohort study of over one million Danish children which shows no evidence supporting an increased risk for autoimmune, atopic or allergic, or neurodevelopmental disorders associated with early childhood exposure to vaccines with aluminum-base adjuvants, and a study of antibodies induced by mRNA-1273 and NVX-CoV2373 COVID-19 vaccines which show that polyclonal antibodies against a single site on the spike N-terminal domain show immunodominance, high diversity, and limited cross-reactivity, indicating the need to direct antibody responses away from this site. Hosts: , ,...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about how flies and milk-snatching might contribute to influenza virus H5N1 among dairy cattle, the recent pertussis oubreak and measles epidemic before Dr. Griffin discusses monoclonal antibody therapy can enrich for RSV variants before deep diving into recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Sinopharm’s COVID-19 vaccine, where to find PEMGARDA, provides information for...
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From the 2025 annual meeting of the American Society for Virology, Charlie Rice, 2020 Nobel Laureate in Physiology or Medicine, talks with Vincent and Kathy about his career and the scientific difficulties he and his laboratory encountered in their attempts to achieve replication of hepatitis C virus in cells in culture. Hosts: and Guest: Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV 2020 (Nobel Prizes) Hepatitis C study (Lancet Gastro Hepatol) Rat hepacivirus for hepatitis C...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello have a morning chat about the measles epidemic and H5N1 in cows before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral drug, whether or not the NB.1.8.1 variant should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University...
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David Barton, Brian Kemp, and Olve Peersen join TWiV to discuss RNA recombination among enteroviruses and its role in foiling poliovirus eradication. Hosts: , , and Guests: , , and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Enterovirus C (J Virol) Poliovirus polymerase L420 (J Virol) Picornavirus RNA recombination (J Virol) and picornavirus RNA recombination (J Virol) Timestamps by Ramsey. Thanks! Intro music is by Send your virology questions and comments...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello note that history is being rewritten for justification of changes in COVID vaccine guidelines including myocarditis incidence and the Great Barrington Declaration ignoring presentations at the April 2025 ACIP, the response by the medical community to these changed guidelines, before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral...
info_outlineIn his weekly clinical update, Dr. Griffin with Vincent Racaniello wail about the attack on science within the US, cancellation of CDC’s committee on infectious diseases, mpox in Sierra Leone, “bird flu” in cats, the ongoing measles outbreak globally, before Dr. Griffin reviews recent statistics on RSV, benefits of vaccination for infants, influenza and SARS-CoV-2 infections the WasterwaterScan dashboard, the high number of childhood deaths during this “flu” season, the May 22 VRBPAC COVID-19 vaccine meeting, where to find PEMGARDA, benefit of remedesivir, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, weight and distinct symptoms of long COVID and contacting your federal government representative to stop the assault on science and biomedical research.
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Links for this episode
- Shut down federal advisory committee on infection prevention…..Make America Healthy Again! (CIDRAP)
- Mpox in Sierra Leone (CIDRAP)
- H5 Bird Flu: Current Situation (CDC: Avian Influenza (Bird Flu) )
- Spike in avian flu cases in cats : spillover into humans? (CIDRAP)
- Measles cases and outbreaks (CDC Rubeola)
- Measles 800 in Texas…. (Texas Health and Human Services)
- Measles outbreak in North Dakota prompts local health officials to quarantine unvaccinated schoolchildren (CNN)
- 2025 Measles outbreak guidance (New Mexico Health)
- Measles and rubella weekly monitoring report: (Government of Canada)
- The Mennonites in a Texas community where measles is spreading (AP News)
- Trust the government? Seriously! West Texans, Mennonites at center of measles outbreak choose medical freedom over vaccine mandates (AP News)
- Measles vaccine recommendations from NYP (jpg)
- Deporting Measles! (AP News)
- Get the FACTS about measles (NY State Department of Health)
- Measles (CDC Measles (Rubeola))
- Measles vaccine (CDC Measles (Rubeola))
- Presumptive evidence of measles immunity (CDC)
- Contraindications and precautions to measles vaccination (CDC)
- Measles (CDC Measles (Rubeola))
- Measles (CDC: Measles Rubeola)
- Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
- Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
- Deaths following vaccination: what does the evidence show (Vaccine)
- Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
- US respiratory virus activity (CDC Respiratory Illnesses)
- Weekly surveillance report: clift notes (CDC FluView)
- Respiratory virus activity levels (CDC Respiratory Illnesses)
- CDC reports 216 child deaths this flu season (AP News)
- Weekly surveillance report: clift notes (CDC FluView)
- New York sees highest flu-related pediatric deaths ever recorded in a season (Times Union)
- Phase 3 Safety and Efficacy Study of Baloxavir Marboxil in Children Less Than 1 Year Old With Suspected or Confirmed Influenza (The Pediatric Infectious Disease Journal)
- FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
- RSV: Waste water scan for 11 pathogens (WastewaterSCan)
- US respiratory virus activity (CDC Respiratory Illnesses)
- RSV-Network (CDC Respiratory Syncytial virus Infection)
- Interim Evaluation of Respiratory Syncytial Virus Hospitalization Rates Among Infants and Young Children After Introduction of Respiratory Syncytial Virus Prevention Products (CDC: MMWR)
- US infant mortality dropped in 2024: RSV vaccine? (AP News)
- Infant Mortality Dashboard (CDC: National Center for Health Statistics)
- Waste water scan for 11 pathogens (WastewaterSCan)
- COVID-19 deaths (CDC)
- COVID-19 national and regional trends (CDC)
- Wastewater Measures of SARS-CoV-2 Accurately Predict Frequency of Symptomatic Infections in the Community (JID)
- Origin of SARS-CoV-2
- The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2 (Cell)
- COVID-19 variant tracker (CDC)
- SARS-CoV-2 genomes galore (Nextstrain)
- COVID-19 infection history as a risk factor for early pregnancy loss (BMC Medicine)
- New recommendations seek treatments for post-Lyme disease condition (CIDRAP)
- Immunogenicity and Safety of Influenza and COVID-19 Multicomponent Vaccine in Adults ≥50 YearsA Randomized Clinical Trial (JAMA)
- Combo flu-COVID vaccine shows good immune response, safety in older adults (CIDRAP)
- US FDA advisers to discuss COVID-19 vaccine recommendations on May 22 (Reuters)
- Interim Clinical Considerations for Use of COVID-19 Vaccines in the United States (CDC: COVID-19)
- COVID-19 vaccine VRBPAC May 22 (FDA)
- Where to get pemgarda (Pemgarda)
- EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
- Infusion center (Prime Fusions)
- CDC Quarantine guidelines (CDC)
- NIH COVID-19 treatment guidelines (NIH)
- Drug interaction checker (University of Liverpool)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- What to do when sick with a respiratory virus (CDC)
- When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids,dexamethasone at the right time (OFID)
- Anticoagulation guidelines (hematology.org)
- Remdesivir associated with reduced mortality in hospitalized COVID-19 patients (BMC Infectious Diseases)
- Real-world evidence shows remdesivir tied to less death in hospitalized COVID patients (CIDRAP)
- Daniel Griffin’s evidence based medical practices for long COVID (OFID)
- Long COVID hotline (Columbia : Columbia University Irving Medical Center)
- The answers: Long COVID
- Excess weight is associated withneurological and neuropsychiatric symptoms in post-COVID-19 condition (PLoS One)
- Identification of soluble biomarkers that associate with distinct manifestations of long COVID (Nature Immunology)
- Reaching out to US house representative
- Letters read on TWiV 1218
- Dr. Griffin’s COVID treatment summary (pdf)
- Timestamps by Jolene Ramsey. Thanks!
Intro music is by Ronald Jenkees
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Content in this podcast should not be construed as medical advice.