This Week in Virology
TWiV discusses the latest worrisome Executive Order on oversight of federal grantmaking, RFK Jr winds down mRNA viral vaccine development, Lenacapavir, a drug for AIDS prevention and treatment, and how respiratory virus infections awaken dormant metastatic breast cancer cells in lungs. Hosts: , , and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Oversight of (Whitehouse.gov) gets a Christofascist (Rasmussen Retorts) HHS winds down (HHS) by COVID vaccines (JAMA) review...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello re-address the dangers of drinking raw milk, the Legionnaire’s outbreak in Harlem and results of a vaccine knowledge survey done by emergency departments before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, reports of influenza-associated acute necrotizing encephalopathy or neuropsychiatric events in children, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Pfizer and MODERNA vaccines against the JN.1...
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TWiV reports the administration putting a choke hold on billions of NIH health research funding, US Senators tell scientists they want to protect the NIH budget, then review a classic experiment showing the mechanism of DNA replication, and explain how jumbo phage DNA is transcribed in a membrane-bound compartment before transfer into proteinaceous “nucleus” compartment. Hosts: , , , , , and Angela Mingarelli Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV 5:13 Chokehold on billions in (WSJ)...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the recent Salmonella typhimurim outbreak, the ousting of another CBER director, confirmation of a new CDC director and results of a recent pool about vaccine safety and trust before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, a new anti-influenza antibody that can be combined with neuraminidase inhibitors, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Sinopharm’s COVID-19 vaccine, where...
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TWiV explains a cohort study of over one million Danish children which shows no evidence supporting an increased risk for autoimmune, atopic or allergic, or neurodevelopmental disorders associated with early childhood exposure to vaccines with aluminum-base adjuvants, and a study of antibodies induced by mRNA-1273 and NVX-CoV2373 COVID-19 vaccines which show that polyclonal antibodies against a single site on the spike N-terminal domain show immunodominance, high diversity, and limited cross-reactivity, indicating the need to direct antibody responses away from this site. Hosts: , ,...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about how flies and milk-snatching might contribute to influenza virus H5N1 among dairy cattle, the recent pertussis oubreak and measles epidemic before Dr. Griffin discusses monoclonal antibody therapy can enrich for RSV variants before deep diving into recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Sinopharm’s COVID-19 vaccine, where to find PEMGARDA, provides information for...
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From the 2025 annual meeting of the American Society for Virology, Charlie Rice, 2020 Nobel Laureate in Physiology or Medicine, talks with Vincent and Kathy about his career and the scientific difficulties he and his laboratory encountered in their attempts to achieve replication of hepatitis C virus in cells in culture. Hosts: and Guest: Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV 2020 (Nobel Prizes) Hepatitis C study (Lancet Gastro Hepatol) Rat hepacivirus for hepatitis C...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello have a morning chat about the measles epidemic and H5N1 in cows before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral drug, whether or not the NB.1.8.1 variant should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University...
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David Barton, Brian Kemp, and Olve Peersen join TWiV to discuss RNA recombination among enteroviruses and its role in foiling poliovirus eradication. Hosts: , , and Guests: , , and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Enterovirus C (J Virol) Poliovirus polymerase L420 (J Virol) Picornavirus RNA recombination (J Virol) and picornavirus RNA recombination (J Virol) Timestamps by Ramsey. Thanks! Intro music is by Send your virology questions and comments...
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello note that history is being rewritten for justification of changes in COVID vaccine guidelines including myocarditis incidence and the Great Barrington Declaration ignoring presentations at the April 2025 ACIP, the response by the medical community to these changed guidelines, before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral...
info_outlineIn his weekly clinical update, Dr. Griffin with Vincent Racaniello debate the changes in FDA vaccine approval policy especially how it is applied to COVID-19 vaccines and restricts vaccine availability/usage and Novavax’s vaccine, mpox on surfaces and in the air, “bird flu”, the ongoing measles outbreak globally before Dr. Griffin reviews recent statistics on RSV, benefits of vaccination for infants, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, the high number of childhood deaths during this “flu” season, the May 22 VRBPAC COVID-19 vaccine meeting, where to find PEMGARDA, prolonged steroid and antibiotic therapies, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, cognitive impairment in long COVID and contacting your federal government representative to stop the assault on science and biomedical research.
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Links for this episode
- FDA to issue new vaccine approval guidance amid questions over coronavirus shots (Washington Post)
- FDA vaccine committee meeting(Reuters)
- Evidence-based approach to COVID-19 vaccination (NEJM)
- FDA CBER townhall: new COVID019 vaccination approval mechanism (YouTube)
- FDA poised to restrict access to COVID vaccines, our own Dr. Griffin is cited! (NY Times)
- Novavax approval letter (FDA)
- We giveth and taketh away: Novavax approved but restricted use (AP News)
- FDA approves Novavax COVID vaccine with stricter new conditions (NY Times)
- History behind public health falsehoods– vaccine and autism (NPR)
- Making vaccines less accessible-RFK Jr making MAHA! (PBS News Hour)
- Kenneday says DO NOT to take medical advice from him, the HHS secretary…hummmm (NY Times)
- Staying up to date with COVID-19 vaccines (CDC: COVID-19)
- How science lost America’s trust and surrendered health policy to skeptics (WSJ)
- HHS stops recommendation of COVID-19 shots for children and pregnant women (Reuters)
- No more routine COVID-19 vaccines for children and pregnant women (WSJ)
- House to investigate Pfizer for allegedly delaying COVID-19 vaccines (Reuters)
- Statement on the antigen composition of COVID-19 vaccines (WHO)
- WHO advisers say current strains OK for COVID vaccine production (CIDRAP)
- We can’t remain indifferent to suffering: Catholic Church now champions HPV vaccination (DailyNation)
- Air and surface sampling for mpox in UK (Eurosurveillance)
- Researchers report mpox DNA, live virus on surfaces and in air from patients’ rooms(CIDRAP)
- USDA reported H5N1 bird flu detection in wild birds (CDC: Avian Influenza)
- USDA reported H5N1 in poultry (CDC: Avian Influenza)
- HPAI Confirmed Cases in Livestock(USDA Animal and Plant Health Inspections Service)
- H5 bird flu: current situation (CDC: Avian Influenza)
- Bird flu (CDC: Avian Influenza)
- Measles cases and outbreaks (CDC Rubeola)
- Measles and rubella weekly monitoring report: (Government of Canada)
- Measles vaccine recommendations from NYP (jpg)
- Get the FACTS about measles (NY State Department of Health)
- Measles (CDC Measles (Rubeola)
- Measles vaccine (CDC Measles (Rubeola)
- Presumptive evidence of measles immunity (CDC)
- Contraindications and precautions to measles vaccination (CDC)
- Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
- Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
- Deaths following vaccination: what does the evidence show (Vaccine)
- Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
- US respiratory virus activity (CDC Respiratory Illnesses)
- Weekly surveillance report: clift notes (CDC FluView)
- Respiratory virus activity levels (CDC Respiratory Illnesses)
- Weekly surveillance report: clift notes (CDC FluView)
- FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
- RSV: Waste water scan for 11 pathogens (WastewaterSCan)
- US respiratory virus activity (CDC Respiratory Illnesses)
- RSV-Network (CDC Respiratory Syncytial virus Infection)
- Waste water scan for 11 pathogens (WastewaterSCan)
- COVID-19 deaths (CDC)
- COVID-19 national and regional trends (CDC)
- COVID-19 variant tracker (CDC)
- SARS-CoV-2 genomes galore (Nextstrain)
- Interim Clinical Considerations for Use of COVID-19 Vaccines in the United States (CDC: COVID-19)
- COVID-19 vaccine VRBPAC May 22 (FDA)
- Where to get pemgarda (Pemgarda)
- EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
- Infusion center (Prime Fusions)
- CDC Quarantine guidelines (CDC)
- NIH COVID-19 treatment guidelines (NIH)
- Drug interaction checker (University of Liverpool)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- What to do when sick with a respiratory virus (CDC)
- When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids,dexamethasone at the right time (OFID)
- The clinical impact of prolonged steroid therapy in severe COVID-19 patients (BMC Pulmonary Medicine)
- Anticoagulation guidelines (hematology.org)
- Antibiotic Treatment in Patients Hospitalized for Nonsevere COVID-19 (JAMA Network Open)
- Daniel Griffin’s evidence based medical practices for long COVID (OFID)
- Long COVID hotline (Columbia : Columbia University Irving Medical Center)
- The answers: Long COVID
- Self-reported health, neuropsychological tests and biomarkers in fully recovered COVID-19 patients vs patients with post-COVID cognitivesymptoms (PLoS One)
- Vortioxetine for Cognitive Impairment in Major Depressive Disorder During Post-COVID Syndrome (Journal of Clincial Psychiatrist) Reaching out to US house representative
- Letters read on TWiV 1220
- Dr. Griffin’s COVID treatment summary (pdf)
- Timestamps by Jolene Ramsey. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
Content in this podcast should not be construed as medical advice.