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Kevin Klatt: Nutrition, health, MAHA and GLP-1

Razib Khan's Unsupervised Learning

Release Date: 03/15/2025

Noah Carl and Bo Winegard: probing the intellectual darker web show art Noah Carl and Bo Winegard: probing the intellectual darker web

Razib Khan's Unsupervised Learning

On this episode of Unsupervised Learning, Razib talks to Bo Winegard and Noah Carl, the editors behind the online publication , founded in 2022. Winegard and Carl are both former academics. Winegard has a social psychology Ph.D. from Florida State University, and was an assistant professor at Marietta College. He was an editor at  before moving to Aporia. Carl earned his Ph.D. in sociology from Oxford University. He was a research fellow at St. Edmund’s College, Cambridge, before becoming a contributor to The Daily Skeptic and UnHerd, and a managing...

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Tim Lee: 2025 and the driverless car revolution show art Tim Lee: 2025 and the driverless car revolution

Razib Khan's Unsupervised Learning

Today Razib talks to , a   on Unsupervised Learning. Lee hosts . Lee covered tech more generally for a decade for , , and . He has a master's degree in computer science from Princeton. Lee writes extensively about general AI issues, from  to the state of . But one of the major areas he has focused on is . With expansion of Waymo to , and this June’s debut of Tesla’s robotaxis, Razib wanted to talk to Lee about the state of the industry. They discuss the controversies relating to safety and self-driving cars. Is it...

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Bonus monologue: Finland as Germania show art Bonus monologue: Finland as Germania

Razib Khan's Unsupervised Learning

This podcast accompanies my post . The two preprints at the heart of this post are,  and .

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Laura Spinney: rise of the proto-Indo-Europeans show art Laura Spinney: rise of the proto-Indo-Europeans

Razib Khan's Unsupervised Learning

Today Razib talks to Laura Spinney, Paris-based British author of the forthcoming . A science journalist, translator and author of both fiction and non-fiction, she has written for,,,, and. Spinney is the author of two novels,  and , and a collection of oral history in French from Lausanne entitled Rue Centrale. In 2017, she published , an account of the. She also translated Swiss writer Charles-Ferdinand Ramuz's novel  into English. Spinney graduated with a Bachelor of Science degree in Natural Sciences from Durham University and did a journalism...

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Bonus monologue: man the hybrid monster show art Bonus monologue: man the hybrid monster

Razib Khan's Unsupervised Learning

Today, Razib talks about a new paper, : Understanding the history of admixture events and population size changes leading to modern humans is central to human evolutionary genetics. Here we introduce a coalescence-based hidden Markov model, cobraa, that explicitly represents an ancestral population split and rejoin, and demonstrate its application on simulated and real data across multiple species. Using cobraa, we present evidence for an extended period of structure in the history of all modern humans, in which two ancestral populations that diverged ~1.5 million years ago came...

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John Sailer: a time of troubles in higher education show art John Sailer: a time of troubles in higher education

Razib Khan's Unsupervised Learning

On this episode of the podcast Razib talks to John Sailer. Sailer is currently the director of higher education policy and a senior fellow at the Manhattan Institute. He covers issues of academic freedom, free speech, and ideological capture in higher education. Sailer has written for the Wall Street Journal, the Free Press and Tablet Magazine. Sailer holds a master’s degree in philosophy and education from Columbia University, and a bachelor’s degree in politics, philosophy, and economics from The King’s College. Prior to joining the Manhattan Institute, he was a senior fellow at the...

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Jacob Shell: academia must diversify or die show art Jacob Shell: academia must diversify or die

Razib Khan's Unsupervised Learning

On this episode of Unsupervised Learning Razib talks to . Shell is a professor of geography at Temple University and author of , and the . Educated at Columbia and Syracuse universities, Shell is active on social media, where he comments extensively on the politicization of the academy. The conversation begins with Shell’s piece in Compact Magazine, . The more than 3,000-word essay argues that academia must diversify ideologically to save itself, but also engage in a wider range of scholarship. Shell points out that US academia has become an ideological...

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Matt Welch: from blog pioneer to podcasting mainstay show art Matt Welch: from blog pioneer to podcasting mainstay

Razib Khan's Unsupervised Learning

On this episode of Unsupervised Learning Razib talks to . He co-founded the Prague-based newspaper Prognosis in the early 1990’s and later worked as an opinion section editor for the Los Angeles Times. From 2008-2016, Welch served as editor-in-chief of Reason magazine, where he currently holds the position of editor-at-large. He co-authored  and wrote . Today, Welch co-hosts  podcast with Kmele Foster and Michael Moynihan. Razib and Welch first go back to his days in Eastern Europe, and how they shaped his views on foreign...

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Bonus monologue: ancient North Africans and the Green Sahara show art Bonus monologue: ancient North Africans and the Green Sahara

Razib Khan's Unsupervised Learning

On this episode of Unsupervised Learning Razib comments on a new paper in Nature,. Here is the abstract: Although it is one of the most arid regions today, the Sahara Desert was a green savannah during the African Humid Period (AHP) between 14,500 and 5,000 years before present, with water bodies promoting human occupation and the spread of pastoralism in the middle Holocene epoch1. DNA rarely preserves well in this region, limiting knowledge of the Sahara’s genetic history and demographic past. Here we report ancient genomic data from the Central Sahara, obtained from...

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Andrew Song: cooling the planet with technology show art Andrew Song: cooling the planet with technology

Razib Khan's Unsupervised Learning

On this episode of Unsupervised Learning, Razib talks to , co-founder of . An NYU graduate with a degree in economics, Song was a member of the  class of winter 2016. Before becoming a founder, Song worked at firms involved in data analytics and artificial intelligence. A repeat attendee at the Founders Fund “Hereticon” conference, Song’s company has been profiled ,  and . Razib and Song first talk about the current state of climate, or more precisely, climate change and anthropogenic global warming. Song argues that the...

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On this episode of Unsupervised Learning Razib talks to Kevin Klatt, a metabolism researcher, dietitian and science communicator. Klatt holds a BA in biological anthropology from Temple University and a PhD in Molecular Nutrition from Cornell University. Before a current appointment as a research scientist at UC Berkeley, he was a postdoctoral fellow at Baylor College of Medicine. Klatt’s primary platform to communicate about nutrition, health and molecular biology is his Substack. He is also an associate editor at the American Journal of Clinical Nutrition.

Recently Klatt has been writing about the “MAHA” pivot, “Make America Healthy Again,” driven by RFK Jr.’s appointment as head of Health and Human Sciences. Razib and Klatt talk about new directions driven by RFK Jr.'s focus on preventative health and skepticism of pharmaceuticals. Klatt points out that the past two decades have seen a massive shift away from funding nutritional studies, in contrast to the massive budgets of big pharma. He argues that we now really find ourselves without enough information to outline a public health policy given the underfunding of nutritional cohort studies. If MAHA is going to be a serious movement, it needs to drive a reallocation of funds. Razib and Klatt also touch on the cultural shift over the last decade on the Right, where something like “raw milk” switched from being coded as left-wing to being squarely right-wing. They also consider mounting skepticism of mainstream medicine, including vaccination, that seems to be associated with MAHA and in particular RFK Jr. Klatt also addresses the role that GLP-1 drugs are having in driving down obesity rates in the USA, and how pervasive their use might be in the near future.