Beneath the Surface
A Healio podcast hosted by Joel M. Gelfand, MD, discussing the latest news and hot topics in the field of dermatology.
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Addressing JAK inhibitor safety in alopecia with Brett King, MD, PhD
06/04/2025
Addressing JAK inhibitor safety in alopecia with Brett King, MD, PhD
In this episode, guest Brett King, MD, PhD, discusses the efficacy of Janus kinase (JAK) inhibitors for the treatment of alopecia areata and conversations with patients surrounding medical pauses. • Intro 0:29 • Brett King, MD, PhD 0:41 • When a patient comes to the office with alopecia areata and want to go on a JAK inhibitor, how do you counsel them about their likelihood for significant hair regrowth? 1:35 • Is your estimate of roughly fifty percent rate from data, or from your own experiences with patients? 6:03 • How do you explain boxed warnings to patients using or thinking about using JAK inhibitors? 8:29 • Gelfand and King on the challenges presented by the current data on alopecia areata patients using JAK inhibitors. 12:02 • Is it true that patients experience hair loss quickly after going off JAK inhibitors? 12:49 • How do you manage these challenges in real-world clinical practice? 13:40 • With JAK, how do you deal with the issue of non-follow-up patients? 17:42 • Thank you, Dr. King. 19:55 Brett King, MD, PhD, is an associate professor of dermatology at Yale School of Medicine. We’d love to hear from you! Send your comments/questions to Dr. Gelfand at . Follow Dr. Gelfand on . King can be reached on X and on . For more, be sure to visit the video blog on Healio.com. Disclosures: Gelfand reports no relevant financial disclosures. King reports having financial relationships with AbbVie, AltruBio Inc, Almirall, Amgen, AnaptysBio, Apogee Therapeutics, Arena Pharmaceuticals, Aslan Pharmaceuticals, BiologicsMD, Bristol Meyers Squibb, Concert Pharmaceuticals, Eli Lilly, Equillium, Horizon Therapeutics, Eli Lilly and Company, Incyte, Janssen Pharmaceuticals, LEO Pharma, Merck, Otsuka/Visterra, Pfizer, Q32 Bio, Regeneron, Sanofi Genzyme, Sun Pharma, Takeda, TWi Biotechnology and Ventyx Biosciences.
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How to embrace AI responsibly with Roxana Daneshjou, MD, PhD
05/07/2025
How to embrace AI responsibly with Roxana Daneshjou, MD, PhD
In this episode, guest Roxana Daneshjou, MD, PhD, discusses the role of artificial intelligence in dermatology practice, and the future of AI models in medicine. • Intro 0:29 • Roxana Daneshjou, MD, PhD 0:45 • What is artificial intelligence? 1:10 • What led to this largely academic endeavor becoming deployable? 2:36 • How is AI being deployed in health care today? 5:36 • What is currently deployable about AI in the dermatology space? 7:56 • How long do you think it will be before dermatologists are using AI in their typical practice? 12:23 • Gelfand and Daneshjou on the dangers of AI models in health care. 17:06 • How much of a concern is diversity in clinical practice when it comes to AI and how do we navigate this as clinicians? 20:28 • Can you predict how long it will take for patients to come into a physician’s office with an AI-generated diagnosis and treatment plan? 23:18 • Thank you, Dr. Daneshjou. 26:35 Roxana Daneshjou, MD, PhD, is an assistant professor of biomedical data science and dermatology at Standford University. We’d love to hear from you! Send your comments/questions to Dr. Gelfand at Follow Dr. Gelfand on . Daneshjou can be found @RoxanaDaneshjou on X and on Instagram. For more, be sure to revisit the video blog on Healio.com. Disclosures: Gelfand reports no relevant financial disclosures. Daneshjou reports having stock options from Revea and MDalgorithms; receiving personal fees from Pfizer, Frazier Healthcare Partners and L'Oreal outside the submitted work; having a patent pending for 17/937 714; and serving as a member of American Academy of Dermatology Augmented Intelligence Committee.
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