Generation Health
Every week, we bring cutting edge research and time tested best practices for helping you live a long, healthy life. Following in the footsteps of our founder (Joe DiMatteo), we are the second generation of a family dedicated to helping you live better & longer. Diet, exercise, supplementation & pharmacology are critical tools.
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The Truth About Ultra-Processed Foods
04/13/2026
The Truth About Ultra-Processed Foods
Ultra-Processed Foods (UPFs) are currently the primary target of nutritional science, linked by various studies to nearly every major negative health outcome. This wave of research recently led California to become the first state to ban UPFs from school lunches. However, a significant problem remains: there is no universal, clinical definition for what actually constitutes an "ultra-processed" food. In this episode, Dante DiMatteo (PharmD) and Joey DiMatteo (PharmD, CCN) cut through the noise to provide a balanced, evidence-based perspective on the UPF controversy. We move beyond the headlines to answer: - The Definition: What does "ultra-processed" actually mean in a clinical context? - The Nuance: Are there specific UPFs that are safe—or even beneficial? - The Risks: What are the verified physiological dangers of a high-UPF diet? - The Reality: How do socioeconomic factors like poverty and education impact our food choices? Stop the "information overload" and gain a usable framework for navigating the modern grocery store with clarity and confidence. We love questions! Comment below or email us: questions@askjoedimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:23 - Show Intro 00:52 - Ultra-Processed Food Ban 01:56 - Why we're talking about ultra-processed foods (again) 03:10 - What is ultra-processed food? 07:23 - Are ultra-processed foods less desirable? 08:25 - Do we all have the same understanding of food classification? 10:04 - Correlation vs. Causation 13:46 - Examples of "healthy" and "unhealthy" ultra-processed foods 19:32 - Yogurt as an example 22:00 - How Europe classifies foods 23:38 - Food labels 26:26 - Takeaway 28:18 - Other problems with food studies 35:44 - What happens when foods are processed? 40:04 - Admitting our personal bias 43:10 - Show outro SHOW NOTES: 1) What if UPFs aren't the villain? (MedPage Today) - https://tinyurl.com/2aypshdn 2) CA Bans UPFs in Schools (CA.gov) - https://tinyurl.com/yep8wupy 3) MAHA Defines UPFs - https://tinyurl.com/28dn6hpp DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Pain Management's Dirty Drug
03/30/2026
Pain Management's Dirty Drug
Tramadol, a drug with more than 16 million U.S. prescriptions last year, is often viewed as the "safer opioid." However, new evidence suggests that perception is not just flawed, but dangerous. Pharmacist, Dante DiMatteo (PharmD), looks at the risks, including cardiac events and seizures, why it's still used, and what non-opioid pain solutions actually help. What's in the Bottle? New bone health products: Bone Base Essentials and Bone PRO Essentials! Pharmacist Joey DiMatteo (PharmD) takes us through what each product is specifically designed to do, who they're for, and how to use them. Whether you're trying to rebuild bone denisty or just keep the healthy bones you have, there's a lot more to bone health than calcium. Joey talks through bone resorption & remodeling, osteoclasts, osteoblasts, and why protein is probably more important than calcium. We love questions! Comment below or email us: questions@askjoedimatteo.com ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:27 - Show Intro 01:07 - Tramadol Troubles 01:48 - What is Tramadol? 03:47 - Who is taking Tramadol? 04:35 - Details of the study 06:18 - Perceived efficacy 11:57 - Cardiac risk 14:07 - Kidney function risk 15:23 - Should you ask your doctor about this? 18:00 - Bone health & bone health supplements 19:15 - How bone actually works 20:23 - Bone health hierarchy of importance 25:20 - Bone Base Essentials 29:42 - Bone Pro 32:14 - Who is this for? 33:13 - Medications for bone health 34:47 - What else can cause bone loss? 36:40 - Why is protein important for bone health? 39:19 - Hormones 44:57 - Other takeaways 46:23 - Show Outro SHOW NOTES: 1) Tramadol for chronic pain (BMJ) - https://tinyurl.com/b2c5r43h 2) Lipid Replacement Therapy (NIH) - https://tinyurl.com/238rb7th 3) Phosphatidylcholine's functions (NIH) - https://tinyurl.com/ys86m7cn 4) Phospholipid ebb and flow (NIH) - https://tinyurl.com/mr2m8mhz 5) Activation of lipoprotein lipase (NIH) - https://tinyurl.com/5n754wpa 6) Uptake and metabolism of 3H-fatty acid labelled lecithin (NIH) - https://tinyurl.com/4jwfbxpm 7) Effect of a hypercholesterolaemic diet (NIH) - https://tinyurl.com/mry8uksm 8) Protective effect of polyunsaturated phosphatidylcholine - https://tinyurl.com/yc4wjh6f 9) Water permeability and mechanical strength of polyunsaturated lipid bilayers (NIH) - https://tinyurl.com/57ruszhz 10) Effect of polyunsaturated phosphatidylcholine on lipid structure (NIH) - https://tinyurl.com/3dbxbnwx 11) Lipid replacement/antioxidant therapy (NIH) - https://tinyurl.com/7xa8565h DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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SSRIs: The Nutrient Gap
03/16/2026
SSRIs: The Nutrient Gap
Are your antidepressants leaving you feeling physically drained? In this episode, Joey DiMatteo (PharmD) leads an evidence-based discussion on how SSRIs often cause hidden nutrient deficiencies that can hinder your mental health progress and reduce the effectiveness of the antidepressants. We break down the research and science behind drug-induced nutrient depletion, the specific vitamins you are likely missing, and the professional-grade solutions to restore your well-being. Additionally, Joey & Dante DiMatteo (PharmD) discuss the groundbreaking shift in pediatric guidelines: why early peanut introduction is the key to ending the peanut allergy epidemic. These new guidelines have already caused a 43% drop in childhood peanut allergies! Get the clarity you need from trusted medical experts who work on the front lines of pharmacy every day. We love questions! Comment below or email us: questions@askjoedimatteo.com ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:31 - Show Intro 01:11 - SSRIs and Nutrients 02:33 - How do SSRIs work? 04:03 - The link with methylation 05:52 - The link with CoQ10 06:52 - What else is critical to overall wellbeing? 10:21 - Other vitamins and minerals that help 12:15 - Which supplements to take while on SSRIs 13:44 - Other things to check 14:20 - Potential drug interactions 22:32 - Peanut Allergies have plummeted in children 24:03 - More details about the study 26:31 - What is the IgE? 28:54 - Why have peanut allergies reduced? 32:08 - What are the new suggestions for peanut allergies? 35:39 - Show Outro SHOW NOTES: 1) Folate in Depression (NIH) - https://tinyurl.com/2ka38bfa 2) Genes and SSRI-Associated Sexual Dysfunction (NIH) - https://tinyurl.com/4wpru9m2 3) Therapy for SSRI-Resistant Major Depression (NIH) - https://tinyurl.com/2w4a96uw 4) L-methylfolate for Major Depression (BMJ) - https://tinyurl.com/2wasv3dx 5) Guidelines for Early Food Introduction and Allergy (AAP) - https://tinyurl.com/4suncxjc 6) Peanut Allergy Rates Dropped (Article) - https://tinyurl.com/ynct84vv DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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130/80: The New PREVENT Standard
03/02/2026
130/80: The New PREVENT Standard
In this episode, we are diving into a topic that—quite literally—gets people’s blood pumping! We are looking at the brand new, 2025 American Heart Association and American College of Cardiology Hypertension Guidelines (AKA The PREVENT Standard), and to help us decode this massive document, we’ve got Dante DiMatteo (PharmD) in the hot seat. The medical community is calling this a "watershed moment." We’re moving from just looking at a number on a cuff to understanding the whole system—heart, kidneys, and metabolism. So what changed? What does it mean for you and your health? Generation Health explains it all! We love questions! Comment below or email us: questions@askjoedimatteo.com ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:24 - Show Intro 01:22 - New Blood Pressure Guidelines 02:43 - What has been updated? 04:59 - How is kidney function related to blood pressure? 06:44 - Mechanisms of blood pressure and cognitive decline 08:58 - What are healthy blood pressure readings? 10:08 - How is someone diagnosed for high BP? 15:22 - What has changed? 19:44 - Changes to pharmacology 25:04 - Other pharmacology changes 26:28 - Changes to lifestyle modifications 32:23 - Show Outro SHOW NOTES: 1) 2025 Guideline For High Blood Pressure in Adults (JACC Journals) - https://tinyurl.com/2hudprv5 2) Updated Hypertension Guidelines (Pharmacy Times) - https://tinyurl.com/mrxn7tkt 3) About PREVENT Risk Calculator (AHA) - https://tinyurl.com/mspjtyh2 4) PREVENT Online Calculator (heart.org) - https://tinyurl.com/3f7wxz6r DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Alzheimer's & Lithium Orotate Link
02/16/2026
Alzheimer's & Lithium Orotate Link
Lithium appears to contribute to cognitive preservation during aging and a new study looks at what happens to the brain when lithium is deficient, possibly leading to Alzheimer's disease. Better still, it looks like increasing the brain's lithium levels may actually reverse the effects. Lithium orotate is getting a glow-up and we're excited for it! Also, the "magic pill" may finally be real. Wegovy, one of the popular new GLP-1 weight-loss medications is now available as a daily oral prescription! How does it differ from injections and how is dosing affected? Is it cheaper than the shots? We love questions! Comment below or email us: questions@askjoedimatteo.com ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:29 - Show Intro 01:38 - Study: Alzheimer's and Lithium Deficiency 02:52 - What is Lithium? 04:26 - What was studied? 06:47 - Details about the animal study 08:55 - How is lithium protecting the brain? 12:22 - Lithium in drinking water 13:28 - Takeaways 16:21 - Wegovy Pill 17:31 - Details of the Wegovy Pill 19:45 - Do you need to titrate up? 20:36 - If it's working, do you need to take more? 22:49 - What's the difference between the pill and injectable? 23:59 - Differences in cost 25:13 - Other points 27:43 - Dietary suggestions while on Wegovy 29:54 - Show outro SHOW NOTES: 1) Lithium and Alzheimer's (Nature) - https://tinyurl.com/aywhpx2h 2) Lithium deficiency and onset of Alzheimers (NIH) - https://tinyurl.com/y2dxvmdf 3) New GLP-1 Pill Compared to Shot (Web MD) - https://tinyurl.com/mt2mvtpv 4) Wegovy Pill in High Demand (NBC News) - https://tinyurl.com/ktb84h54 5) Wegovy pill now available across America (PR Newswire) - https://tinyurl.com/2t6uda9w DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Government Food Fight
02/02/2026
Government Food Fight
At the top of the year, U.S. Department of Health and Human Services Secretary Robert F. Kennedy, Jr. and U.S. Department of Agriculture Secretary Brooke Rollins released the Dietary Guidelines for Americans, 2025–2030, the most significant reset of federal nutrition policy in decades. Emphasizing “real food,” the food pyramid we grew up with has essentially been turned upside down. Dante DiMatteo (PharmD) breaks down the changes: What's good, what's bad and what families should take away from this messy government food fight. We love questions! Comment below or email us: questions@askjoedimatteo.com ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:26 - Show Intro 01:15 - New dietary guidelines 02:41 - What does this update affect? 05:18 - Why is this a "hostile takeover?” 12:12 - Specifics of the new guidelines 12:23 - Changes to Protein 17:07 - Changes to Fat 20:57 - The paradox that's occurring 23:32 - What the guideline authors are focused on 28:29 - Biomarker-dependent decision making 35:48 - Carbohydrate/Insulin Model 41:10 - International Reaction to these changes 42:19 - Blue zones 44:30 - Takeaways 45:35 - Show Outro SHOW NOTES: 1) Official Gov't Site - https://realfood.gov/ 2) The Scientific Foundation for the Dietary Guidelines (CDN) - https://tinyurl.com/586crtx3 3) Anabolic Resistance of Muscle Protein Turnover (NIH) - https://tinyurl.com/mvxp9xy7 4) Moderating "the great debate" (NIH) - https://tinyurl.com/4dhtadtb 5) Carbohydrate-insulin model (Royal Society) - https://tinyurl.com/mwa6m7cf 6) Historic Reset of U.S. Nutrition Policy (USDA) - https://tinyurl.com/64wxzt8k DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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The VO2 Max Trap
01/19/2026
The VO2 Max Trap
VO2 Max is having a moment. It seems every fitness influencer and longevity specialist has decided to focus on it as the key metric for determining your health. Is it important? Yes. But making that the key indicator of fitness is a trap. Then, Dante fields a listener question: What do you do when red wine turns your face, well...bright red. How can you enjoy a glass while avoiding that awful face flush and the terrible feeling that comes along with it? We love questions! Comment below or email us: questions@askjoedimatteo.com ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:23 - Show Intro 01:22 - VO2 Max 03:52 - What is VO2 Max? 05:51 - Who is Steve Magnus? 09:56 - What does VO2 Max tell you? 10:46 - What should you look at instead of VO2 max? 11:39 - Running economy 13:10 - Lactate Threshold 16:00 - Does VO2 max really matter? 18:49 - Is Zone 2 cardio related to VO2 max? 25:33 - Viewer Question: Red Wine Flush 26:04 - Why does this happen? 27:19 - What are the chemical issues with alcohol? 32:47 - Is there a "trick" with red wine to avoid flush? 34:51 - What to do with the data 40:29 - Show Outro SHOW NOTES: 1) VO2 Max & metabolic health (Study) - https://tinyurl.com/bdh2jh6u DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Why You Hate Your Workout
01/05/2026
Why You Hate Your Workout
What effect does your personality have on how you feel about exercise? Do traits like extroversion or openness impact what works best for you? A new study suggests it could be the key factor in why some workouts work for some people and not others! Dante DiMatteo (PharmD) unpacks all the details of the study, and offers suggestions from the research of how we can use our personality to actually enjoy the exercise we all need! We love questions! Comment below or email us: questions@askjoedimatteo.com ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:33 - Show Intro 01:23 - Exercise Personality 02:42 - What is the Big 5 Personality Test? 05:53 - The Study's Goals 09:57 - What were the results of the test? 12:14 - Personality and Enjoyment of exercise 20:08 - Personality and Program Adherence 23:36 - How do we turn this into useful data? 35:37 - Show Outro SHOW NOTES: 1) Personality Predicts Exercise Intensities (Study) - https://tinyurl.com/3xcrazkf DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Women Need More Testosterone
12/15/2025
Women Need More Testosterone
Testosterone isn't just for men! We look at the effects testosterone has on everything from thyroid function, sexual dysfunction, and basic joy in life. We cover proper testing as well as the therapies, lifestyle changes, and supplements that can help boost low levels in women. Next, Dante examines the popular paleo diet and research that looks at the effects evolution, ecology, and economy has on the human diet. Put simply: paleo isn't really paleo! So what did our ancestors actually eat? We love questions! Comment below or email us: questions@askjoedimatteo.com ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:29 - Show Intro 01:06 - Women & Testosterone 01:58 - What does testosterone do in women? 02:56 - Hormone Testing 06:21 - Sex Hormone Binding Globulin (SHBG) 07:51 - Free T3 09:02 - Chronic Cortisol 10:25 - Symptoms of Low-T in women 14:49 - Ways to naturally increase free testosterone 18:32 - Takeaways 21:02 - Paleo Diet isn’t Actually Paleo 22:39 - Question about fasting and paleo 23:56 - What is the Paleo Diet? 27:49 - What's the point? 31:15 - So what should you do? 38:01 - Our meat vs. the meat of our ancestors 39:56 - Dante's advice to his friend 46:09 - Takeaway 47:45 - Show Outro SHOW NOTES: 1) Testosterone therapy in men with androgen deficiency (NIH) - https://tinyurl.com/2uy6phe8 2) Impact of oral contraceptives on globulin and androgen levels (NIH) - https://tinyurl.com/3ztvtj24 3) Zinc and Testosterone Levels (NIH) - https://tinyurl.com/ywhyz3d6 4) Vitamin D and Testosterone (NIH) - https://tinyurl.com/ynyb842d 5) Evolution of Human Diet (NIH) - https://tinyurl.com/2wcwhyf7 DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Eat Clean, Reduce ADHD
12/01/2025
Eat Clean, Reduce ADHD
A 2012 study (INCA) that only just came across our desk has huge implications for folks with Attention-Deficit Hyperactivity Disorder (ADHD), particularly kids! Joey DiMatteo (PharmD, CCN) examines how an elimination diet improves ADHD in children. How much can food choice really affect behavior and can restricting certain foods help manage ADHD symptoms? The study was on children, but the implications are universal! When a listener (and Josiah) ask Dante about wearing a weighted vest, it's the perfect tie-in for looking at a study about weighted vests and long-term weight loss. Should everyone be wearing these things? We love questions! Comment below or email us: questions@askjoedimatteo.com ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! SHOW NOTES: 1) Elimination Diet and ADHD Children (ResearchGate) - https://tinyurl.com/4jv6r73k 2) Weighted Vest Use During Weight Loss (Obesity) - https://tinyurl.com/yc7wyrw2 CHAPTERS: 00:28 - Show Intro 01:40 - Clinical Trial: ADHD & Elimination Diets 02:29 - What they studied 03:28 - Phase 1 04:12 - Phase 2 07:33 - Types of allergies 09:45 - Elimination Diet 11:28 - Signs of High IGG 13:09 - Elimination diet forever? 17:25 - Tyler's experience with ADHD 18:47 - Behavioral Therapy 21:29 - Discussion: Weighted Vests 23:12 - Difference between weighted vests and ruck sacks 24:00 - Are weighted vests good or not? 25:22 - Good ways to use a weighted vest 30:19 - Vests for endurance training 33:59 - Study about weighted vests 35:13 - How long was the study? 37:25 - Study Findings 41:59 - Additional tidbits 44:21 - Researcher takeaways 46:54 - Show Outro DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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FDA Flips: Menopause & HRT
11/17/2025
FDA Flips: Menopause & HRT
At last, the FDA has decided to remove the black box warning from topical hormone replacement therapies (HRTs) for menopause after years of pushback from women, and a comprehensive scientific review. We look at the original research that lead to the warnings and present evidence for their removal. Women were suffering unnecessarily because good research was mis-applied, and it took two decades for the government to catch on. Next, we look at a study showing that nearly half of type 2 diabetes patients exhibit micronutrient deficiencies, with vitamin D being the most prevalent, followed by magnesium and vitamin B12. We discuss how to assess your individual needs and how to supplement effectively. Finally, heading into Thanksgiving, Josiah helps us refocus and reframe the personality clashes and stress that always come around whenever family gets together. If you've got a question, we'd love to hear it! Just drop it in the comments or send us an email (questions@askjoedimatteo.com)! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! SHOW NOTES: 1) FDA Removes Warning From Menopause Hormone Therapies (Pharmacy Times) - https://tinyurl.com/mrxxvv69 [Note: Latest Data] 2) Doctors urge FDA to remove outdated warnings (WWL TV) - https://tinyurl.com/yc96uu4e 3) Progesterone for vasomotor symptoms (NIH) - https://tinyurl.com/2htxfwp7 4) Progesterone for treatment of menopausal women (NIH) - https://tinyurl.com/yc6mnu9x 5) Progesterone for perimenopausal night sweats and hot flushes (NIH) - https://tinyurl.com/2e3y3dxv 6) Progesterone may decrease perimenopausal hot flashes, night sweats (Endocrine Society) - https://tinyurl.com/yc4vcbmc 7) Progesterone Therapy for Menopause (Healthline) - https://tinyurl.com/ythxtnt8 8) Micronutrient Deficiencies in Type 2 Diabetes Patients (Pharmacy Times) - https://tinyurl.com/bdfzphks CHAPTERS: 00:25 - Show Intro 01:12 - HRT Blackbox Article 01:27 - A note from Joey 04:35 - Summary of what's going on 05:23 - Findings from the study 09:35 - When will the warning be removed? 10:51 - Transdermal vs. Oral Estradiol 12:49 - Why would you choose oral over transdermal? 14:52 - Local Estrogen 15:50 - Discussion: Macronutrient Deficiencies with T2D 16:50 - Info about the study 18:24 - Most common deficiencies 20:02 - What are the overlaps 22:45 - What to do with this info? 27:17 - Words of Wisdom: Gratitude & Family 29:15 - Be Anxious about Nothing 32:54 - Trust in the Unseen 36:16 - Changing Your Perspective 48:10 - Takeaway 49:01 - Show outro DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Q&A Special (Fall 2025)
11/03/2025
Q&A Special (Fall 2025)
Two working pharmacists answering your questions! How can you safely switch asthma medications for kids? What supplements help with recovery from shingles? How much protein do kids actually need? Does Wegovy cause blindness? And that's not even the full list! If you've got a question, we'd love to hear it! Just drop it in the comments or send us an email (questions@askjoedimatteo.com)! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:20 - Show Intro 01:42 - Asthma Medication Question 13:43 - Supplements for Shingles Recovery 19:37 - Vibration Plate Question 25:34 - How Much Protein Does an 8 Year Old Need? 37:59 - Potential Side Effects of Wegovy 44:03 - Hypertrophy Training Question 1:01:09 - Show Outro DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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ADHD & Melatonin
10/20/2025
ADHD & Melatonin
New research suggests that melatonin may be closely linked to the severity of ADHD symptoms in children. Genetic variations affecting melatonin production could contribute to ADHD symptoms, particularly through disrupted sleep patterns, suggesting the potential benefits of healthy sleep routines in managing ADHD symptoms. Plus, "What's In The Bottle?" Advanced Pre-Workout Sour Surge! Formulated with patented, clinically studied ingredients to support energy, endurance, performance, and recovery, it’s designed for informed consumers who demand transparency, effective dosing, and real results. No hidden blends or generic fillers! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:26 - Show Intro 02:08 - Study: Melatonin & ADHD 04:02 - Study conclusions 06:31 - What causes ADHD 07:22 - Interleukin 6 10:57 - Circadian Rhythm 14:30 - Genes 17:40 - ADHD and sleep disorders 19:15 - Our products that contain melatonin 21:51 - What’s in the Bottle: Advanced Pre-workout 22:06 - What is a pre-workout? 23:04 - Who should use a pre-workout? 23:59 - Ingredients 26:30 - Nitric Oxide 29:12 - Stimulants 31:08 - What does caffeine do? 33:37 - Show Outro SHOW NOTES: 1) Role of melatonin in ADHD symptoms (PsyPost) - https://tinyurl.com/4frnfp9v 2) Genetic risk of melatonin and ADHD (ScienceDirect) - https://tinyurl.com/2p4ujxhv 3) Advanced Pre-Workout Sour Surge (Ask Joe DiMatteo) - https://tinyurl.com/2u6srzut DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Bone Health Supplements & FDA Natural Thyroid Change
10/06/2025
Bone Health Supplements & FDA Natural Thyroid Change
When a listener question about calcium & vitamin D creates a great starting point for a dive into the way multiple nutrients work together to improve bone health. The FDA recently announced a plan to take action against natural, animal-derived thyroid medications. Why is the FDA suddenly taking action against a medication so old it predates the FDA itself? What are the advantages for the 1.5 million Americans taking this “unapproved” prescription? ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:25 - Show Intro 01:37 - Viewer Question: Calcium and Vitamin D 02:23 - Calcium 05:45 - Vitamin D 07:14 - Takeaway 08:31 - Bone Density 10:27 - Alternatives to store-bought calcium 12:19 - Better types of calcium 13:36 - Calcium Study 14:47 - Magnesium 15:31 - K2 16:28 - Vitamin D 17:08 - Japanese Study 18:23 - Article: FDA vs. Unapproved Thyroid Medications 19:43 - What is pig thyroid? 21:57 - Why is the FDA doing this? 22:41 - Why would someone take pig thyroid? 27:56 - Risks of T3 28:53 - Punchline for those using desiccated thyroid 30:53 - Show Outro SHOW NOTES: 1) Desiccated thyroid for hypothyroidism? (NIH) - https://tinyurl.com/4kr6v5uy 2) FDA Addresses Unapproved Thyroid Medications (FDA) - https://tinyurl.com/ypxcpb66 3) Ossein-hydroxyapatite vs calcium carbonate to prevent bone loss (NIH) - https://tinyurl.com/9bz6sxmj 4) Bone Base Essentials (Ask Joe DiMatteo) - https://tinyurl.com/4rcaspen 5) Suboptimal magnesium (NIH) - https://tinyurl.com/rd67erd9 6) Magnesium, inflammation, and obesity (NIH) - https://tinyurl.com/wtnvv3tn 7) Circulating levels of vitamin K2 (NIH) - https://tinyurl.com/mwhb87vh 8) Where do Americans get their nutrients? (NIH) - https://tinyurl.com/mr2hxpj8 9) Exercise and mineral status of athletes (NIH) - https://tinyurl.com/y3svnbyr 10) Magnesium and osteoporosis (NIH) - https://tinyurl.com/mwcp2nsw 11) Magnesium supplementation and osteoporosis (NIH) - https://tinyurl.com/yy243vy5 12) Treatment of fibromyalgia syndrome (NIH) - https://tinyurl.com/mu4nm233 13) Magnesium and Fibromyalgia (NIH) - https://tinyurl.com/yc28bpfp 14) Vitamin K and vitamin D status (NIH) - https://tinyurl.com/mr53eunx 15) Vitamin K-Dependent Carboxylation of Osteocalcin (NIH) - https://tinyurl.com/yebcn2u4 16) Supplementation helps decrease bone loss in healthy postmenopausal women (NIH) - https://tinyurl.com/mtf7cc8f 17) Vitamin D metabolism (NIH) - https://tinyurl.com/4edr3hx4 18) Calcium, vitamin D, milk consumption, and hip fractures (NIH) - https://tinyurl.com/mpac7mwv 19) Vitamin K(2) and vitamin D(3) on bone mineral density (NIH) - https://tinyurl.com/59sb2usu DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Traumatic Test, Healthier Kids?
09/22/2025
Traumatic Test, Healthier Kids?
The "Presidential Fitness Test" has a long history. Started in the 60's, radically changed under President Obama, and now returning under President Trump, it serves as an excellent example of good intentions with not-so-great results. Will its return help solve the childhood obesity crisis? We dig into the good, the bad, the awkward, and everything in between. Plus, “What’s in the Bottle,” you ask? Our new Whey Protein Essentials! Whey Protein is an excellent nutritional supplement for individuals looking for a pure protein source made from grass-fed and rBGH-free cows to complement an active and healthy lifestyle. The formula is a rich source of BCAAs, bioactive peptides, antioxidants, and immunoglobulins with a host of health benefits. Using a quality protein supplement is an excellent way to hit your macros! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:30 - Show Intro 02:22 - Presidential Fitness Test 07:27 - What was tested? 12:04 - Was this a good test? 14:46 - Obama's change 22:39 - Additional Tidbit 24:13 - Trump Admin bringing back original test 27:10 - Is this going to fix the problem? 32:36 - Article from Steve Magnus 41:14 - WitB: Whey Protein Essentials 41:51 - What has changed? 42:09 - Whey concentrate vs. Isolate 43:38 - Advantages to whey protein isolate 45:01 - Who should consider taking a protein supplement? 46:37 - Why is protein intake important? 48:03 - How much protein should we have daily? 50:13 - How do you use Protein Essentials? 53:17 - Why choose whey protein essentials? 54:41 - Bioavailability 56:18 - Show Outro SHOW NOTES: 1) Trump Restores Public School Program (Newsweek) - https://tinyurl.com/yc2fbb7v 2) Presidential Fitness Test is Good, Actually (Slate) - https://tinyurl.com/4re4ybce 3) Whey Protein Essentials (Ask Joe DiMatteo) - https://tinyurl.com/52m9uhx9 4) Exercise promotes BCAA catabolism (NIH) - https://tinyurl.com/yrm948dj 5) Whey protein as a source of bioactive peptides for functional foods (ScienceDirect) - https://tinyurl.com/29bucjh4 6) Protein - Which is Best? (NIH) - https://tinyurl.com/55axwpc8 7) Health Benefits of Whey Protein (David Publishing) - https://tinyurl.com/34zhpfnc 8) Whey protein attenuates strength decline after muscle damage (NIH) - https://tinyurl.com/mr4yu2s4 9) Functional properties of whey and essential amino acids (NIH) - https://tinyurl.com/45uw2vs5 10) Functional food relevance of whey protein (ScienceDirect) - https://tinyurl.com/33fbyabj DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Prebiotics, Fiber & Lower Cholesterol
09/08/2025
Prebiotics, Fiber & Lower Cholesterol
Dante answers a listener question about how prebiotics, fiber supplements, and whether they interact with Lipitor. There's a lot of hype around prebiotics, but is any of it justified? Plus, a new study illustrates the opposing roles dopamine and serotonin play in shaping our decisions and learning processes. Joey discusses how understanding these key brain chemicals can lead to faster learning and avoiding the same spiral of chasing dopamine with things like social media doom scrolling. ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:28 - Show Intro 01:25 - Listener Question: Prebiotics 02:05 - What are Prebiotics? 04:03 - Good vs. Bad Gut Bacteria 09:20 - What are naturally occurring prebiotics? 13:59 - Can prebiotics curb appetite? 17:09 - Will prebiotics interfere with statins? 20:20 - What is the pre/pro/postbiotic process? 22:11 - Why do we care about postbiotics? 26:35 - Prebiotic Soda 28:44 - Serotonin and Dopamine 30:17 - What are Dopamine and Serotonin? 32:41 - Synergy Hypothesis & Opponency Hypothesis 33:39 - Study Findings 41:41 - Connection with depression and addiction 46:25 - Show Outro SHOW NOTES: 1) Dopamine and serotonin's opposing roles (PsyPost) - https://tinyurl.com/52sbb8a2 2) Dopamine and Serotonin (Study) - https://www.nature.com/articles/s41586-024-08412-x DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Can Trump Fix Drug Prices
08/25/2025
Can Trump Fix Drug Prices
President Trump, now in his second term, has signed two executive orders he believes will lower prescription drug prices. He's pressuring "big pharma", trying to cut out PBM's (Pharmacy Benefits Managers), and restricting how much Medicare and Medicaid will pay. Is it enough? Are these even the right targets? What will all of this mean when picking up a prescription? We dig into the details and take a look at what all of this means for your wallet. ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowYTM Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 01:16 - Executive Orders Overview 03:21 - Most Favored Nation 05:50 - How did we get here? 06:25 - Price Controls 08:10 - Patent Laws & Exclusivities 10:51 - What are PBMs? 12:55 - Big 3 PBMs 21:53 - Direct to Consumer Rx 23:44 - Medicare Price Negotiations 31:58 - Show Outro SHOW NOTES: 1) Prescription Drug Pricing (White House) - https://tinyurl.com/2bcj6dbt 2) Plan to pressure drug companies to lower costs (ABC News) - https://tinyurl.com/5x98wp6n 3) Lowering Drug Prices (White House) - https://tinyurl.com/3cak5y5m 4) Fact Sheet: Lower Prescription Drug Prices (White House) - https://tinyurl.com/4bchne2v 5) Letter to Drug Manufacturers (X) - https://tinyurl.com/4hcc7rna DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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The Diabetic Brain
07/14/2025
The Diabetic Brain
When two different studies came out looking at the association of type 2 diabetes and Alzheimer's risk, we knew we had to dig in! What exactly are the risks? What is the connection? Do any medicines help negate those risks? Joey has the details. What's in the Bottle? Creatine Essentials! Creatine has been getting a ton of press lately, and for good reason! While the body makes a limited amount of creatine on its own, nearly everyone can benefit from supplementing with it. It improves athletic performance by allowing muscles to work harder for just a bit longer. What's more, several recent studies are showing that it helps the brain by reducing the worst effects of poor sleep. ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:32 - Study: Type 2 Diabetes & Alzheimer’s 02:55 - Study Summary 07:42 - Study: Diabetes Meds & ALZ Risk 09:41 - Study Summary 11:09 - GLP-1 and SGLT-2 impact on dementia 14:35 - Obesity & Alzheimer’s 16:58 - What’s in the Bottle: Creatine Essentials 17:47 - What is Creatine? 20:02 - Who is creatine supplementation for? 25:01 - Are there risks? 28:20 - How do you use Creatine Essentials? 30:31 - Show Outro SHOW NOTES: 1) Type 2 Diabetes Rewires the Brain (NeuroscienceNews) - https://tinyurl.com/4skhvcs5 2) Diabetes Rewires the Brain (Pharmacy Times) - https://tinyurl.com/yszyksey 3) Diabetes drugs may slash Alzheimer's risk (MedicalNewsToday) - https://tinyurl.com/tjmxmrmy 4) GLP-1, Parkinson’s Disease (The New England Journal of Medicine) - https://tinyurl.com/465njwjv 5) Treatment for people with Parkinson's disease (Lancelet) - https://tinyurl.com/yjunh4s6 6) BCAAs on Muscle During Exercise (NIH) - https://tinyurl.com/2dpbz9vu 7) Whey protein as a source of peptides (Research Gate) - https://tinyurl.com/4wfz937u 8) Protein - Which is Best? (NIH) - https://tinyurl.com/3athvss8 9) Health Benefits of Whey Protein (ResearchGate) - https://tinyurl.com/mry4mvh4 10) Whey protein isolate attenuates strength decline (NIH) - https://tinyurl.com/2d44pa5w 11) Functional properties of whey (NIH) - https://tinyurl.com/mr48wuff 12) Relevance of whey protein (ScienceDirect) - https://tinyurl.com/p7p2uf8n DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Got a Coach?
06/30/2025
Got a Coach?
Josiah unintentionally set us up for a conversation about a fantastic new study: Do you REALLY need a coach or trainer if you want to start exercising? Will they actually make a difference? That was the question a new study asked and the answer was a resounding "YES!" In “What’s in the Bottle?,” Joey explains exactly how the body responds to stress, and particularly chronic stress. From there, he explains the use cases for each of our adrenal support products, Adrenal Advanced Essentials & Stress Support Essentials. What you need depends entirely on where you are in the chronic stress response! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:32 - Show Intro 00:58 - Josiah's Marathon Experience 07:27 - Coaching Study 11:39 - Punchline 12:57 - How were the findings measured? 17:04 - What’s in the Bottle: Adrenal Supplements 18:15 - What is stress? 20:59 - Cortisol 23:13 - DHEA 23:53 - Adrenal Advanced Essentials 26:01 - Adaptogenic Herbs 28:12 - Vitamin Blend 28:51 - Dosing 29:48 - Adrenal Calm Essentials 30:37 - What's in ACE? 33:21 - Dosing 34:36 - How these differ from other supplements 38:27 - Show Outro SHOW NOTES: 1) Impact of Coach Behavior (Study) - https://tinyurl.com/2epv5bxt 2) Rhodiola Rosea (Study) - https://tinyurl.com/2aehvtk9 3) Trial of SHR-5 Rhodiola Rosea Doses (Study) - https://tinyurl.com/bddmp5z8 4) Stimulating Effect of SHR-5 on Students (Study) - https://tinyurl.com/39j6ecza 5) Iron Advanced Essentials (Ask Joe DiMatteo) - https://tinyurl.com/trrc8smy 6) Eleutherococcus senticosus (Study) - https://tinyurl.com/mvua6a46 7) Heavy Exercise & Adaptogens (Study) - https://tinyurl.com/33c7x6nf 8) ESP-102 improves memory (Study) - https://tinyurl.com/4hv9fwdd 9) Chronic Stress and HPA Axis (Study) - https://tinyurl.com/55z593w5 10) Vit C and Adrenals (Study) - https://tinyurl.com/mryuxpex 11) Pantothenic Acid & Glutathinone (Study) - https://tinyurl.com/4929fpma DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Your Brain on Insulin Resistance
06/16/2025
Your Brain on Insulin Resistance
How is your brain affected by what you (over) eat? We examine a study which shows that even a brief period of overeating ultra-processed, high-calorie snacks can lead to lasting disruption in the brains insulin response & liver fat accumulation. Behind the Counter, shocking almost no one, science proves that weed makes you dumber. “What’s in the Bottle?,” you ask? Iron Advanced Essentials! Iron supports prenatal and cognitive health, as well as energy balance. ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:31 - Show Intro 00:39 - Behind the Counter 03:26 - Discussion: Insulin & Obesity Risk 03:49 - Brain insulin and obesity risk 04:41 - How does insulin work? 05:34 - Insulin sensitivity 07:03 - Insulin and the brain 08:38 - The study 16:54 - What’s in the Bottle: Iron Advanced Essentials 17:42 - What's in the update? 18:50 - Why would you take this supplement? 20:47 - How do we get iron from our diet? 21:52 - Energy Balance 22:38 - What's in Iron Advanced Essentials? 23:55 - Dietary Intake of Iron 25:39 - How do you become deficient in iron? 28:54 - Dosage 31:16 - Show Outro SHOW NOTES: 1) Birth & Brain Growth (Article) - https://tinyurl.com/mrnz7cu2 2) Cannabis Reduces Brain Activity (Article) - https://tinyurl.com/57cec8zh 3) Rapid Dietary Effects on Brain Insulin and Obesity Risk (Article) - https://tinyurl.com/4dhs3vus 4) Brain Insulin & High Calories (Study) - https://tinyurl.com/bdcrhk93 5) Iron Advanced Essentials (Ask Joe DiMatteo) - https://tinyurl.com/trrc8smy 6) Dietary Reference Intakes (NIH) - https://tinyurl.com/48tfycdf 7) Iron metabolism in man (NIH) - https://tinyurl.com/3ypzyym7 8) Physiology and molecular biology of iron absorption (NIH) - https://tinyurl.com/yydnztek 9) Absorption of heme iron (NIH) - https://tinyurl.com/bdhkmbfc 10) Bioavailability of minerals in legumes (NIH) - https://tinyurl.com/put2zfda 11) Approaches to improve iron bioavailability from complementary foods (NIH) - https://tinyurl.com/bmejns2w 12) Iron absorption from the whole diet in men (NIH) - https://tinyurl.com/4mykhexe 13) Iron nutrition and absorption (NIH) - https://tinyurl.com/3avx6np6 14) Iron supplementation in menstruating women with low ferritin (NIH) - https://tinyurl.com/4uv5mby7 15) Prevent and Control Iron Deficiency in the U.S. (CDC) - https://tinyurl.com/23f3ncux DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Testosterone & TRT: Black Box Warning
06/02/2025
Testosterone & TRT: Black Box Warning
You don't see this very often! The FDA has REMOVED a "black box warning" from testosterone products used in TRT and other hormone therapies. The FDA uses box warnings when there is serious concern about a potential side effect. Seeing one removed is almost completely unheard of! Joey and Dante break down all the details on what's changing, the research behind it, and what it means for the millions of men using testosterone replacement therapy. ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:25 - Show Intro 01:26 - Unrelated Question 05:26 - Discussion: FDA Changing labeling on TRT 10:31 - How often does the FDA remove warnings? 13:11 - More about the study 16:50 - Dosing in the study 22:14 - VA study 26:22 - Show Outro SHOW NOTES: 1) FDA Issues New Labeling (Article) - https://tinyurl.com/2nsu7rvy 2) FDA Official Announcement - https://tinyurl.com/4xh5skz5 3) Cardiovascular Safety of TRT (Study) - https://tinyurl.com/4xmaf7mt 4) VA study of TRT & CV (Study) - https://tinyurl.com/46exs6da DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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The Zero Calcium Score Danger
05/12/2025
The Zero Calcium Score Danger
When a doctor suspects plaque build-up in the arteries and vessels of a patient's heart, a non-invasive CT scan will often be used to detect the presence of calcium. That results are represented as a Calcium Score (Coronary Artery Calcium or CAC). So if the results come back and you have a low or even zero CAC, you're safe, right? Unfortunately, it's not that easy. Dante has the details based on a listener question. Joey gives us details on a product with a VERY specific use: Prenatal Complete with DHA! Creating life is not the time to use just any old prenatal, and Joey explains the details of why ours is worth the investment! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! SHOW NOTES: 1) The Zero CAC Paradox (Study) - https://tinyurl.com/2pd476yp DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Beyond BMI: Redefining Obesity
04/28/2025
Beyond BMI: Redefining Obesity
Is obesity a disease or does it lead to disease? Or is it merely a corollary with disease? What exactly is obesity? Where is the cutoff... and why? With questions like this raging in the medical community and popular-health world, the Lancet pulled together dozens of doctors and scientists to try and bring clarity based on the broadest and most well-established research. What they came up with is both critically important... and difficult to parse for the non-professional. This episode is extra long, but with obesity (and clinical obesity) comprising the single greatest challenge for Americans and the health of their families, we decided it was worth it! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:34 - Show Intro 01:22 - Unrelated Question 04:18 - Article: Is Obesity a disease state? 06:04 - What was the definition of obesity? 09:27 - What is the new definition of obesity? 10:55 - How is it diagnosed? 15:18 - What are the downsides of calling obesity a disease? 19:37 - Pre-clinical vs. clinical obesity 28:37 - FDA Indications for obesity medications 35:23 - Public perception of obesity 44:28 - Waist circumference 48:10 - Body roundness index 49:18 - Show Outro SHOW NOTES: 1) Definition & Diagnosis of Obesity (Lancet) - https://tinyurl.com/y6bnkwjs 2) Is obesity a disease? (Economist) - https://tinyurl.com/mrxrmtja DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Pregnancy and Forever Chemicals
04/14/2025
Pregnancy and Forever Chemicals
Joey digs into a new study linking prenatal exposure to FPAS via contaminated drinking water to an increase in childhood cancer. We unpack the research and discuss what women can do to protect their babies. This research has huge implications for young families! After that, Joey tells us exactly what's so exciting about one of our newest products, Ovarian Advanced Essentials. Designed to target women's hormone issues, Ovarian Advanced Essentials is built with the exact ratios of D-chiro Inositol and myoinositol that have been shown in research to the most help, particularly to women with PCOS. When hormones become unbalanced, the symptoms can be wide-ranging. Don't miss the chance to set things straight naturally! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:31 - Show Intro 01:34 - Study: Prenatal exposure to PFAs in drinking water 01:53 - What are PFAs? 04:22 - What health risks to PFAs pose? 09:31 - What do we do about PFAs? 14:17 - WitB: Ovarian Advanced Essentials 14:45 - What are ovaries? 15:08 - What does OAE do? 15:48 - Who is it for? 16:46 - What is PCOS? 20:37 - Study 23:31 - What is in OAE? 23:48 - Inositol 26:11 - Other nutrients 27:55 - Dosing 28:49 - Show Outro SHOW NOTES: 1) PFAS and Childhood Cancer - https://tinyurl.com/bddtfxu9 2) PFAS & Cancer (Study) - https://tinyurl.com/3x2barmn 3) Ovulation in PCOS (Study) - https://tinyurl.com/3pnn5jzx DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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After Years of Ambien...
03/31/2025
After Years of Ambien...
We field a question from a listener about her husband’s Ambien use and dive into all things related to sleep aids. Watch for the good, bad, and the ugly of sleeping pills and other remedies for a better night’s sleep! Behind the counter, researchers further explain how Metformin scientifically helps Type 2 diabetes patients and does even more than that! Plus, does gut microbiome affect behavior? We examine a study that compares incarcerated women who are considered impulsive and violent and those who aren't. ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:25 - Show Intro 03:15 - Behind the Counter 06:27 - Viewer Question: Ambien & Alternatives 07:33 - Why is Ambien causing these issues? 08:48 - What are peak plasma levels and “clearance?" 15:27 - How is the alcohol affecting this situation? 18:53 - Could diet be a contributing factor? 19:57 - Why should someone take Ambien? 22:59 - Is it typical to stay on Ambien this long? 27:29 - Alternatives to using Ambien 29:39 - Other pharmacological options 31:23 - What does it look like to taper off Ambien? 33:29 - Supplements for sleep 35:03 - Show Outro SHOW NOTES: 1) Unmasking Metformin (SciTechDaily) - https://tinyurl.com/5dhnb2zz 2) Impulse Control (Karger) - https://tinyurl.com/6b5duhrv DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Pancake or Death?
03/17/2025
Pancake or Death?
A widely publicized presentation (https://tinyurl.com/mup49t39) at the American Heart Association conference linked time-restricted eating (AKA intermittent fasting) to a 91% higher risk of cardiovascular death. If true, this has profound implications for anyone that skips breakfast! So... is it true? Also, Joey tells us exactly "What's in the Bottle" of our new Prostate Advanced Essentials! This precise blend of ingredients takes advantage of the latest research in how support the prostate. 90% of men will experience prostate problems at some point in life, so get ahead of it with proper support! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:18 - Show Intro 00:27 - Article: Time-Restricted Eating and Death 03:12 - Takeaway from the study 04:15 - How was this study set up? 06:59 - Is this really about intermittent fasting? 10:30 - Is intermittent fasting healthy? 13:34 - Takeaways 17:43 - What’s in the bottle: Prostate Advanced Essentials 18:51 - What are the symptoms of BPH? 20:47 - Side effects of BPH medications 21:30 - What does this supplement do? 22:55 - What's in Prostate Advanced Essentials? 25:07 - What is Saw Palmetto? 26:16 - What is Stinging Nettle? 28:16 - Which minerals does PAE include? 30:12 - Dosing 30:56 - Show Outro SHOW NOTES: 1) Time-Restricted Eating (Heart.org) - https://tinyurl.com/mup49t39 DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Cancer, Alcohol & Warning Labels
02/17/2025
Cancer, Alcohol & Warning Labels
In the last days of the Biden administration, the Surgeon General called for cancer warnings on alcohol, similar to cigarette packs. Exactly what kinds of cancer risks does alcohol present, and how solid is this data? Will a new warning label actually make any difference? When a listener emails looking for advice on his high cholesterol, Dante draws clear distinctions between what is realistic for supplements to help and what requires the sledgehammer of medicine. ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a weekly podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:32 - Show Intro 01:31 - Article: Link between alcohol and cancer 04:49 - How does consuming alcohol lead to cancer? 07:02 - What types of cancer can alcohol contribute to? 07:40 - Will this warning label change behavior? 17:51 - Raw numbers of the study 19:09 - Is there any benefit to drinking alcohol? 23:52 - Viewer Question: Should I take a statin? 27:34 - Treatment for high LDL cholesterol 30:01 - What are healthy levels of cholesterol? 34:34 - Difference between total cholesterol and LDL 35:59 - The other factors that contribute to cholesterol 37:41 - Takeaway 40:44 - Show Outro SHOW NOTES: 1) Cancer Warnings on Alcohol (NYT) - https://tinyurl.com/ycka5prn 2) Alcohol & Cancer Risk (HHS Site) - https://tinyurl.com/2jaf7ekv DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Keto and Athletic Performance
02/03/2025
Keto and Athletic Performance
Diet trends come and go so quickly that there often isn't enough time for real, hard research to be done on them. This leaves both supporters and detractors making claims based on prior opinion and intuition. When the research does eventually come along, it often gets ignored as everyone has already moved on... but not us! After research and careful consideration, the International Society of Sports Nutrition has released an official position statement on the ketogenic diet and how it effects athletic performance. Even if you don't consider yourself an athlete, their analysis is so well reasoned that it provided an excellent basis for discussing dieting in general as well as keto specifically. Joey DiMatteo gives us a deep-dive on one of our most popular products: Magnesium Essentials! There's a lot more to making an excellent magnesium supplement than meets the eye! Joey explains the different forms, their bio-availability, and the useful place for each of them. ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:32 - Show Intro 01:17 - Behind the Counter 04:49 - Discussion: The Ketogenic Diet 05:22 - ISSN Conclusions on Ketogenic Diet 07:07 - Basics of nutritional science 11:12 - Picking an eating style that works for you 15:15 - Point 1 15:49 - What is ketosis? 18:38 - Points 2-4 21:26 - Point 5 & 6 24:38 - Point 7 25:06 - Punchline 28:37 - Protein Intake & Healthy Aging 32:30 - What’s in the bottle: Mag Essentials 32:59 - What does magnesium do in the body? 37:51 - Types of Magnesium 39:16 - Basic forms of magnesium 40:08 - Higher quality types of magnesium 40:35 - Why a combination magnesium product matters 43:38 - What forms do we offer? 45:57 - Show Outro SHOW NOTES: 1) Butter Recall (Article) - https://tinyurl.com/4k2z2mzw 2) Werewolf Syndrom (NYPost) - https://tinyurl.com/y5s4fs49 3) Keto & Performance (NIH) - https://tinyurl.com/nwxsexvy 4) Keto & Performance (Study) - https://tinyurl.com/2y9tny79 DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Let's talk about Ozempic
02/03/2025
Let's talk about Ozempic
GLP-1 Agonists like Ozempic (Mounjaro, Wegovy, Zepbound) continue to dominate headlines and pharmacy counters. What started as a casual conversation turned into an super-honest, nuanced deep-dive on these blockbuster obesity medications. Dante DiMatteo (PharmD) brings direct answers to all the common questions: Is it cheating? What aren't they telling us? Why can't people just eat less and exercise more? How should we talk about it with friends? Joey DiMatteo (PharmD, CCN) discusses one of our oldest prodcuts, Flora HP Essentials. What exactly is in the bottle? Why would you take a probiotic? What are the specific aims that make this one unique from our other probiotics? ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a weekly podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:31 - Show Intro 01:18 - Discussion: GLP-1 Agonists 12:38 - Is Ozempic a life-long prescription? 20:42 - Advice for talking to others about GLP-1 35:12 - What’s in the Bottle: Flora Essentials 36:23 - What are probiotics? 39:01 - Who needs to take it? 40:40 - Use for C.Diff 42:12 - Dosage 45:56 - Additional Studies 47:28 - Show Outro DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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Thyroid Meds and Bone Loss
01/20/2025
Thyroid Meds and Bone Loss
A major study made headlines when it linked America’s second-most commonly prescribed drug in older adults, Levothyroxine (a thyroid medication), is linked to bone loss and ultimately, osteoporosis, a debilitating bone disease. Should everyone stop taking this medicaiton immediately? We discuss the study and what it actually means for those dealing with low functioning thyroid. Plus, one of our listeners wanted to know if she could save money by taking out Daily Essentials multivitamin instead of six individual supplements. Saving money is always good, but will the results be the same? Find out in this episode! ALL PRODUCTS: https://www.AskJoeDimatteo.com CONNECT: Products - https://askjoedimatteo.com/youtube Questions - questions@askjoedimatteo.com Facebook - https://facebook.com/askjoedimatteo Instagram - https://tinyurl.com/5n6kfwhs PODCAST: Apple Podcasts - https://tinyurl.com/GHShowApple Google Podcasts - https://tinyurl.com/GHShowGoogle Spotify - https://tinyurl.com/GHShowSpotify Rumble - https://rumble.com/user/GenerationHealth YouTube - https://tinyurl.com/57hxe6aj YouTube Clips - https://tinyurl.com/wzk69tbk Generation Health is a weekly podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life! CHAPTERS: 00:31 - Show Intro 01:04 - Unrelated Question: What are your favorite apps? 04:00 - Viewer Question: Single vs. Multivitamins 05:07 - Therapeutic vs RDI supplementation 10:03 - Linda’s Situation 15:26 - Discussion: Levothyroxine & Bone Loss 17:38 - Is Levothyroxine causing bone loss? 24:44 - Takeaways 26:42 - Show Outro SHOW NOTES: 1) Thyroid Med Linked to Bone Loss (RSNA) - https://tinyurl.com/3x4trt98 2) Levothyroxine Use and Bone (RSNA) - https://tinyurl.com/zuw97mnm 3) Med Prescribed to 23M May Cause Bone Loss (Newsweek) - https://tinyurl.com/3easu39k 4) Levothyroxine use and changes in thigh muscles in at-risk participants for knee osteoarthritis (NIH) - https://tinyurl.com/bdcpdyat DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
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