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Implementing Triple Satiety Hormone Activators for Metabolic and Weight Health | Myles Spar, MD & Edward Walker, PhD
04/28/2026
Implementing Triple Satiety Hormone Activators for Metabolic and Weight Health | Myles Spar, MD & Edward Walker, PhD
In this episode of Innovations in Clinical Implementation, recorded live at LongevityFest 2025, hosts Laurie Hofmann and Dr. Lexi Gonzales explore one of the most pressing challenges in metabolic and weight care: how to support meaningful weight loss without compromising lean muscle mass. They are joined by Dr. Myles Spar, a double board-certified physician specializing in integrative internal medicine, and Dr. Edward Walker, researcher at New Zealand’s Plant and Food Research and lead scientist behind Amarasate, the bitter hops extract at the center of ’s appetite control formula. Together, they discuss how triple satiety hormone activation may offer practitioners a valuable tool for supporting metabolic health, preserving muscle, and improving continuity of care before, during, and after GLP-1 therapy. The conversation also covers body composition monitoring, dosing considerations, endogenous GLP-1 support, and how Calocurb Clinical may fit into more comprehensive, lifestyle-forward care models. For access to episode resources, click .
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