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๐ Genes, Gradients, and Game-Changers: FAQs on Hypertrophic Cardiomyopathy
09/17/2025
๐ Genes, Gradients, and Game-Changers: FAQs on Hypertrophic Cardiomyopathy
๐ง Hypertrophic Cardiomyopathy โ A Masterclass from Eugene Braunwald ๐งฌ ๐ Just published in NEJM (Aug 2025): a sweeping, state-of-the-art review on HCM โ from Teareโs first autopsy to myosin inhibitors, AI diagnostics, and gene therapy. ๐ฅ Clinical insights, historical depth, trial data (EXPLORER-HCM, SEQUOIA-HCM, VALOR-HCM), and future-facing advancesโall distilled into one must-read. ๐ SCD prevention, ๐ซ LVOT obstruction, ๐งช MYBPC3/MYH7 mutations, ๐งฌ proteomics, and more. ๐ Essential reading for cardiologists, geneticists, and translational scientists. #HCM #Braunwald #NEJM #Cardiology #PrecisionMedicine #Mavacamten #Aficamten #GeneTherapy #MedicalEducation #SCDprevention
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