info_outline
A patient on immune checkpoint inhibitors with troponin rise: what do you do?
06/08/2026
A patient on immune checkpoint inhibitors with troponin rise: what do you do?
With Novi Yanti Sari, Siloam Hospitals Group, Jakarta - Indonesia and Stephane Ederhy, Hospital Saint-Antoine, Paris - France. In this episode, Novi Yanti Sari speaks with Stephane Ederhy about a challenging and increasingly encountered scenario in modern cardio-oncology: troponin elevation in patients receiving immune checkpoint inhibitors. Using a real-world case of a patient on pembrolizumab presenting with fatigue and borderline troponin rise, the discussion explores the clinical features that raises suspicion for ICI myocarditis. The episode highlights practical approaches to evaluation and management, including the role of serial troponin measurements, ECG, echocardiography, cardiac MRI and endomyocardial biopsy. The discussion also addresses when immunotherapy should be interrupted, when corticosteroid therapy should be initiated, and concludes with practical clinical pearls for clinicians managing immune-related cardiovascular toxicities.
/episode/index/show/e5b291f6-a613-4a54-a8ba-e97aefc26255/id/41489850
