Immune 85: Immune trade-offsImmune explores the immunological diversity in the upper airway, including memory B and T cells and germinal center B cells, and how chronic infection with Plasmodium parasites leads to development of B cell cancers. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode Immune memory diversity in (Nature) How Plasmodium infection (Cell) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/33671212
Immune 84: Gender-affirming therapy and immune responses with Petter BrodinPetter Brodin joins Immune to discuss immune system adaptation in individuals assigned female sex at birth and undergoing gender affirming testosterone therapy (trans-men). Hosts: , , , and Guest: Subscribe (free): , , Become a of Immune! Links for this episode Petter Brodin on Gender-affirming (Nature) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/33190962
Immune Booster #9: Autoimmune diseases with Mark ShlomchikFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with Mark Shlomchik to talk about his career and the research of his laboratory on systemic autoimmune diseases, long-lived B cell immunity, and immunopathogenesis. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32993272
Immune Booster #8: Immunology, metabolism, and exercise physiology with Heather CaslinFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Heather Caslin to talk about her training and the research of her laboratory on how diet and exercise affect innate immune cells in health and disease. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32866622
Immune 83: Immune cells eating other cellsImmune discusses two stories of immune cells eating other cells: microglia engulfing brain neurons to shape cortical development and behavior, and mast cells trapping neutrophils to increase their functional and metabolic fitness. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode Microglia shape (Cell) by mast cells (Cell) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/32733702
Immune Booster #7: Emerging viruses with David MartinezFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with David Martinez to talk about his career, the research of his laboratory on viral pathogens of global health importance, and his advice to be persistent and enjoy the journey. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32661337
Immune Booster #6: From Ghana to heat shock with Robert BinderFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Robert Binder to talk about his career, the research of his laboratory on the role of heat shock proteins in cancer immunosurveillance, and the importance of inspiring students as early as possible to think about science. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32561857
Immune Booster #5: Infections and the gut microbiome with Rafael PolidoroFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with Rafael Polidoro to talk about his career, the research of his laboratory on how the gut microbiome modulates the local and systemic immune responses during infections. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32452127
Immune 82: Bat antibodies are hotImmune reviews the local and systemic responses after human SARS-CoV-2 challenge infection, and how bat antibodies display elevated antigen binding strength and diversity at higher temperatures that are characteristic of flight. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode Responses to human (Nature) Temperature-sensitivity of (Nat Comm) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/32343427
Immune Booster #4: Human autoimmunity with Jane BucknerFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with Jane Buckner to talk about her career, and the research of her laboratory on mechanisms by which regulation of the adaptive immune response fails or is overcome in the setting of human autoimmunity. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32249757
Immune Booster #3: NKT cells and cancer, and DEI in research with Tonya WebbFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Tonya Webb to talk about her career, the role of NKT cells in cancer, and her efforts to ensure diversity, equity, and inclusion in research. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32149897
Immune Booster #2: Sex differences in immune responses with Michal TalFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Michal Tal to talk about her career, sex differences in immune responses, and how one giant mouse uterus changed the trajectory of her research career. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32056472
Immune Booster #1: From bench to bedside to beat HIV with Luis MontanerFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne where meet up with Luis Montaner to talk about his career and his research on boosting the immune system to combat viral diseases or cancer progression. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Links for this episode in research (Res Involv Engag) Susceptibility to during ART (AIDS) experience (J Immunol) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/31982567
Immune 81: T cells and tolerance with Joseph Larkin IIIImmune travels to Chicago for the American Association of Immunologists conference where they meet up with Joseph Larkin III to talk about his career and his research on the contribution of T lymphocyte subsets and functions in maintaining tolerance. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Links for this episode in immunity and autoimmunity (J Immunol Res) COVID-19 booster enhances (Front Nutr) SARS-CoV-2 after maternal immunization (J Perinatol) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/31868322
Immune 80: Intranasal neomycin; sex hormones and skin immunity; and maternal diet and infant microbiomesImmune presents three stories: intranasal neomycin and antiviral immunity, sexual dimorphism in skin immunity, and maternal diet changes infant microbes that alter gut DC responses and respiratory health. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode Intranasal (PNAS) Sexual dimorphism in (Science) Maternal diet and (Immunity) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/31484642
Immune 79: Spa therapy for the immune systemImmune explains how antibody-mediated depletion of myeloid-hematopoietic stem cells in aged mice restores characteristic features of a more youthful immune system, including increasing common lymphocyte progenitors, naive T cells and B cells, while decreasing age-related markers of immune decline. Hosts: , , and Subscribe (free): , . , Become a of Immune! Links for this episode Depleting My-HSC (Nature) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/31471777
Immune 78: Tolerance and tolerating many vaccinesImmune discusses responses in a COVID hypervaccinated individual, synthetically glycosylated antigens for the antigen-specific suppression of established immune responses, gut bacteria–derived serotonin promotes immune tolerance in early life, and mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge. Hosts: , , , and Subscribe (free): , . , Become a of Immune! Links for this episode Adaptive immune responses preserved in (Lancet) Synthetically glycosylated antigens for of established immune responses (Nat Biomed Eng) Gut bacteria–derived serotonin in early life (Sci Immunol) Immune correlates of viral control after in adults (Sci Immunol) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/30552963
Immune 77: Squeezing the most killing out of neutrophilsImmune reviews research showing that the migration of neutrophils between endothelial cells activates bactericidal function via mechanosensing. Hosts: , , , and Subscribe (free): , . , Become a of Immune! Links for this episode activates neutrophil killing (Immunity) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/30135188
Immune 76: Macrophages to the rescue with Juliet MorrisonJuliet Morrison joins Immune to discuss her career and the research of her laboratory showing that pleural macrophages translocate to the lung during infection to promote improved influenza outcomes. Hosts: , , , and Guest: Click arrow to play Download Immune 76 (48 MB .mp3, 67 min) Subscribe (free): , . , Become a of Immune! Links for this episode is broken (Solving for Science) Pleural macrophages during influenza (PNAS) Time stamps by . Thanks! Music by Steve Neal Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/29712778
Immune 75: Ang Cui unveils the cytokine symphonyAng Cui joins Immune to discuss her career and her work on establishing the Immune Dictionary, a compendium of single-cell transcriptomic profiles of more than 17 immune cell types in response to each of 86 cytokines (>1,400 cytokine-cell type combinations) in mouse lymph nodes in vivo. Hosts: , , and Guest: Subscribe (free): , . , Become a of Immune! Links for this episode is broken (Solving for Science) Immune (Nature) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/29262858
Immune 74: Germinal center dynamics with Carla NowosadCarla Nowosad joins Immune to discuss her career and her work on germinal centers, the structure in secondary lymphoid tissues where B cells proliferate, differentiate, and diversify their immunoglobulin genes by somatic hypermutation. Hosts: , , and Guest: Subscribe (free): , . , Become a of Immune! Links for this episode and the intestinal microbiome (Sem Immunol) in gut germinal centres (Nature) B cell (Methods Mol Biol) Immune synapse (Nat Immunol) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/29027558
Immune 73: Big macsImmune reveals the total mass (1.2kg), number (1.8 trillion), and distribution of immune cells in the human body, with macrophages contributing nearly 50% of the total cellular mass. Hosts: , , and Subscribe (free): , . , Become a of Immune! Links for this episode in the human body (PNAS) on Immune 73 Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/28551233
Immune 72: After dark in the library with Ellen RothenbergFrom Cornell University in Ithaca New York, Vincent and Cindy meet with Ellen Rothenberg to review her career in science, starting with work on retroviruses to unraveling transcriptional networks underlying T-cell development and signaling. Hosts: and Guest: Click arrow to play Download Immune 72 (53 MB .mp3, 73 min) Subscribe (free): , . , Become a of Immune! Links for this episode (Nature) (Nat Immunol) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/28121195
Immune 71: Can parasitic worms prevent pandemics?Immune explains how, in a mouse model of roundworm infection with Nippostrongylus brasiliensis, exposure to lung-migrating helminths protects mice against SARS-CoV-2 infection. Hosts: , , and Subscribe (free): , . , Become a of Immune! Links for this episode murine SARS-CoV-2 infection (Sci Immunol) Pandemic (ScienceInsider) on Immune 71 Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/27982653
Immune 70: Immunology of picky eatingImmune explains how mast cells, IgE antibody, and the brain collaborate to promote avoidance of certain foods to evade allergic responses. Hosts: , , and Subscribe (free): , . , Become a of Immune! Links for this episode and immune avoidance behavior (Nature) Immune sensing of food allergens (Nature) Immunology that underlies (Nature) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/27565635
Immune 69: Lung cancer and retrovirusesKevin joins Immune to discuss his work showing that antibodies against endogenous retroviruses promote immunotherapy of lung cancer. Hosts: , , , and Guest: Subscribe (free): , . , Become a of Immune! Links for this episode Antibodies against (Nature) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/27161982
Immune 68: Sins and blessings of immunityImmune discusses immunological imprinting, also called original antigenic sin, in the context of infection with SARS-CoV-2 and influenza virus. Hosts: , , and Download (45 MB .mp3, 76 min) Subscribe (free): , . , Become a of Immune! Links for this episode Immunological (Immunity) imprinting (bioRxiv) Original (J Inf Dis) Are (LJII) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/26880747
Immune 67: Can T cells live forever?Immune explains the results of a study which show that in mice, functional T cells respond to vaccination for over 10 years and 51 successive immunizations, exhibiting supernumerary cell division and longevity. Hosts: , , , and Subscribe (free): , . , Become a of Immune! Links for this episode T cells capable of (Nature) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/26727855
Immune 66: COVID-19 immune memory - what you need to knowImmune discusses the current understanding of immune memory to SARS-CoV-2 infection and COVID-19 vaccines, which supersedes that of any other acute infectious disease. Hosts: , , , and Subscribe (free): , . , Become a of Immune! Links for this episode COVID-19 (Imm Rev) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/26442711
Immune 65: Infection infidelities with Jonathan KaganJon joins Immune to discuss the research of his laboratory on understanding how the innate immune system recognizes and responds to pathogens, and his hypothesis that infection infidelities drive innate immunity. Hosts: , , , and Guest: Subscribe (free): , . , Become a of Immune! Links for this episode Approaching the (Cold Spring Harb Symp Quant Biol) I drive innate immunity (Science) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/25988028
