Immune

A podcast about the body's defenders against disease.

Immune 101: Ink and immunity 02/24/2026

Immune 101: Ink and immunity Immune discusses how tattoo ink accumulates in lymph nodes, promotes inflammation and influences response to two different vaccines. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode IL-9, CD8 cells and vaccines Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/40109095

Immune Booster 23: Critical windows during immune system development with Anna Beaudin 02/17/2026

Immune Booster 23: Critical windows during immune system development with Anna Beaudin Anna Beaudin from University of Utah talks about the key thread of her career, development, and how that influences her research on the events happening during critical prenatal windows shapes everything from the developing immune system to hearing loss. Host: Guest Subscribe (free): , , Become a of Immune! Links for this episode at University of Utah PhD work on Postdoc work on and hematopoietic stem cell development on postnatal immunity Early life inflammation and Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/40108410

Immune Booster #22 T cell signaling and selection with Leslie Berg 02/10/2026

Immune Booster #22 T cell signaling and selection with Leslie Berg Leslie Berg talks about her career studying T cell receptor signaling, T cell development, and the importance of mentors in her career. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode at University of Colorado Anschutz TCR thresholds and ITK (PNAS) Review on TCR signaling (Nat Immunol) Generation of (Mol Cell Bio) in TCR transgenic mice (Nature) Thymic n TCR transgenic mice (Cell) Berg information Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/39993805

Immune 100: Immune turns 100! 01/27/2026

Immune 100: Immune turns 100! The whole Immune gang gathers with special guests Gretchen Diehl and Shruti Naik at The Incubator with an audience to celebrate the 100th episode. Hosts: , , and Guests: and Subscribe (free): , , Become a of Immune! Links for this episode Diehl: Gut development (Nature 2021) Diehl: Bacteria-i (Gut Microbes 2022) Diehl: Microbiota, and colitis (Gut Microbes 2022) Diehl: E. coli-activated inflammation (Cell Rep 2025) Naik: skin inflammation (Science 2012) Naik: IL-17 and (Science 2022) Naik: Human transcriptomics (Sci Immunol 2023) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/39675705

Immune Booster 21: Origins of antigen receptors with David Schatz 01/13/2026

Immune Booster 21: Origins of antigen receptors with David Schatz David Schatz talks about his discovery of Rag genes that are critical for antigen receptor development and how that discovery depended on taking high risks and using approaches that everyone thought could never work. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode Tin non-lymphoid cells (Cell 1988) Identification of (Cell 1989) (Semin Immunol 2004) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/39675220

Immune 99: A Nobel for immune tolerance 12/30/2025

Immune 99: A Nobel for immune tolerance The Immune team discusses the groundbreaking discoveries of regulatory T cells, which was the topic of the 2025 Nobel Prize in Physiology or Medicine. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode Sakaguchi lab (Science 2003) Brunkow and Ramsdell mutation (Nature 2001) on Treg discoveries Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/39384135

Immune Booster 20: Lipid GPS for T cells with Susan Schwab 12/16/2025

Immune Booster 20: Lipid GPS for T cells with Susan Schwab Susan Schwab talks about how she got the research bug, bugs she ate, and her research on how the lipid S1P helps T cells decide- should I stay or should I go. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode Schwab lab Monocytes to regulate T cell movement and immune cell migration Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/39383065

Immune 98: T cells on the brain 11/25/2025

Immune 98: T cells on the brain Immune discusses cross-reactive antibodies to avian influenza neuraminidases and a role for gut-derived T cells in the brain to regulate eating behavior. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode Antibody H5N1 (Cell Host Microbe, 2025) Gut-derived (Nature, 2025) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/39083245

Immune Booster 19: Virus-immune Tug-of-war with Kristian Andersen 11/11/2025

Immune Booster 19: Virus-immune Tug-of-war with Kristian Andersen Kristian Andersen from Scripps Research Institute joins Cindy to talk about how he got interested in virus evolution, how the immune system drives viral adaptation, and what we can learn from this research to better prepare us for the next pandemic. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode Andersen Perspective on of virus emergence Kristian’s appearance Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/38954800

Immune 97: Bystander B cells go bananas 10/28/2025

Immune 97: Bystander B cells go bananas Cindy and Steph discuss a paper that challenges the textbook dogma that B cells must first bind to an antigen for antibody affinity maturation to occur, and a snippet on dysfunctional T cells during bacterial vaginosis. Hosts: and Subscribe (free): , , Become a of Immune! Links for this episode Somatic B cells (Immunity 2025) Dysfunctional vaginosis (J Clin Invest 2025) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/38526480

Immune Booster 18: From Stars to cells with Bali Pulendran 10/14/2025

Immune Booster 18: From Stars to cells with Bali Pulendran Cindy sits down with Bali Pulendran at the AAI 2025 meeting where he told the story of how a childhood fascination with the cosmos grew into a career addressing fundamental questions about the human immune response, and how when an antigen enters the body it is like the big bang in how it initiates immune responses. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode Systems and durability (Nature 2025) World’s (Sem Immunol 2024) Review (Immunity 2010) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/38515325

Immune Booster #17: From unvaccinated to vaccine advocacy with Liz Marnik 10/07/2025

Immune Booster #17: From unvaccinated to vaccine advocacy with Liz Marnik Elizabeth Marnik, also known as Science Whiz Liz, grew up unvaccinated, yet she is now an immunologist, science communicator, and advocate for vaccines–this is her story. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode More about Liz on her on Instagram From the Science Classroom with Science Whiz Liz Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/38464380

Immune 96: How to floss a mouse 09/30/2025

Immune 96: How to floss a mouse Immune discusses the potential future of delivering vaccines by flossing your teeth and how antibodies in human milk shape the normal immune responses in newborns. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode vaccination (Nat Biomed Engineering 2025) vaccine paper (Sci News) Human development (PNAS 2025) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/38330265

Immune Booster #16: Teaching and communicating immunology with Aimee Pugh Bernard 09/16/2025

Immune Booster #16: Teaching and communicating immunology with Aimee Pugh Bernard Cindy speaks with Aimee Pugh Bernard from University of Colorado about her career and her passion for teaching and communicating immunology to the public. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode More about Aimee on her on Instagram Fun Size Science with Fun Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/38195510

Immune 95: Mitochondria for everyone 08/26/2025

Immune 95: Mitochondria for everyone Immune discusses how cancer cells swap mitochondria with T cells and then digs in for a discussion of an unusual checkpoint blockade that failed for cancer but could be repurposed for autoimmune inflammation. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode Cancer cells for metastasis (Nature 2025) Cancer cells to impair them (Nature 2025) PD-L1 binding to CD80 on the same dendritic cell needed for migration (Sci Adv 2025) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/37626375

Immune Booster #15 Vaccine ground rules with Shane Crotty 08/12/2025

Immune Booster #15 Vaccine ground rules with Shane Crotty Cindy talks with Shane Crotty about his teenage days driving 3 ½ hours every weekend to have his first research experience in marine biology, how that eventually led to studying how vaccines work and how we can make them better, and how immunology research and publishing got a turbo-boost during the pandemic. Hosts: Guest: Subscribe (free): , , Become a of Immune! Links for this episode on human upper airway immunity Shane Crotty on immunity Shane Crotty on of SARS-CoV memory Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/37672400

Immune 94: The nose knows 07/29/2025

Immune 94: The nose knows The Immune team goes up the nose to discuss cytotoxic T cells activating complement through secretion of granzyme K to drive inflammatory nasal polyps and how IgA-producing B cells are made in the nose. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode CD8 T cnflammation (Nature 2025) Where IgA producing (Nature 2024) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/37418165

Immune Booster #14: In the eye of immune responses with Darren Lee 07/08/2025

Immune Booster #14: In the eye of immune responses with Darren Lee From the 2024 Society for Leukocyte Biology meeting, Cindy and Brianne talk with Darren Lee to discuss his career, how he got interested in immunology of the eye, and how his team visualizes immune responses of the eye in real time with the hope of better understanding autoimmune uveitis. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Links for this episode The environment (Adv Drug Delivery Rev 2023) Tregs control (Sci Rep 2025) and autoimmune uveitis (J Leuk Biol 2024) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/37080740

Immune 93: Macrophages managing memory B cells 06/24/2025

Immune 93: Macrophages managing memory B cells Vincent and Cindy discuss differences between MPox-specific T cell responses following infection and vaccination, and lymph node macrophage control of memory B cell localization and trafficking that might be important for choosing which arm to get a vaccine. Hosts: and Subscribe (free): , , Become a of Immune! Links for this episode Different infection or vaccination (Nat Comm 2025) responses after vaccination (Cell 2025) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/37080415

Immune Booster #13 Microbiome and regulation of gut inflammation with Justin Wilson 06/10/2025

Immune Booster #13 Microbiome and regulation of gut inflammation with Justin Wilson From the 2024 Society for Leukocyte Biology meeting, Cindy and Brianne sit down with Justin Wilson to talk about how he got into research and his more recent studies on innate immune sensors and the interaction between the gut microbiome and inflammation related to inflammatory bowel disease and cancer. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Links for this episode Francisella tularensis defenses (Infect Immunity) AIM2 s cancer (Nature Med) NLRP12 regulates (Cell Host Microbe) Oral connection (Microbiol Mol Bio Rev) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/36693660

Immune 92: Gut symbiont breaks antibody 05/27/2025

Immune 92: Gut symbiont breaks antibody Steph talks about identification of gut bacteria that can digest protective mucosal antibodies and Vincent covers a new paper on Zika virus that implicates fetal phagocytes in brain invasion, which may provide insight into the devastating microcephaly outcome of infection during pregnancy. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode Gut bacteria (Science) Contribution of fetal mononuclear (Cell) discusses Zika and brain slice infection model. Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/36692420

Immune Booster #12: Innate immunity to Archaea with Holger Heine 05/13/2025

Immune Booster #12: Innate immunity to Archaea with Holger Heine From the 2024 Society for Leukocyte Biology meeting, Immune talks with Holger Heine about the discovery of immune recognition of bacterial lipopolysaccharide and innate immunity to organisms within the kingdom Archaea. Hosts: and Guest: Become a of Immune! Links for this episode TLR8 recognizes human (Front Immunol) The for health and disease (FEBS) Structural insights into mimetics (Nature Comm) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/36524930

Immune 91: People, parasites, plagues, and podcasts 04/29/2025

Immune 91: People, parasites, plagues, and podcasts Immune talks with David Peterson and Kim Klonowski from the University of Georgia about their careers, their People, parasites, and plagues podcast, placental malaria immunity, and and how interferons in the thymus affect T cell repertoire selection. Hosts: , , , and Guests: and Subscribe (free): , , Become a of Immune! Links for this episode podcast protein-specific immunity (Trends in Parasitology) affects T cell repertoire selection (Science Immunology) Dickson Despommier’s book Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/36073595

Immune Booster #11 Immunity to Fungi with Amy Hise 04/09/2025

Immune Booster #11 Immunity to Fungi with Amy Hise From the 2024 Society for Leukocyte Biology meeting, Immune talks with Amy Hise about her career in science, her current research using mouse models for investigating fungal immunity and navigating the challenges of being a mom in science. Hosts: and Guest: drugs to treat Candida fungal infection is y Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/36057955

Immune 90: Immunology of Injury 03/25/2025

Immune 90: Immunology of Injury Immune 90: Immunology of Injury March 25, 2025 From the 2024 Society for Leukocyte Biology meeting at Michigan State University, home of the Spartans, Immune’s Cindy and Brianne talk with Liz Kovacs and Jim Lederer about their careers, dirty mice, old mice, and immunity during trauma. Hosts: and Guests: and Subscribe (free): , , Become a of Immune! Links for this episode Jim Lederer’s and Liz Kovacs’s and Paper on use of also known as natural immune mice Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/35712985

Immune Booster #10 HIV in the brain with Amanda Brown 03/17/2025

Immune Booster #10 HIV in the brain with Amanda Brown Immune Booster #10 HIV in the brain with Amanda Brown March 18, 2025 From the The Society for Leukocyte Biology 2024 conference at Michigan State University, Cindy and Brianne sit down with Amanda Brown from Johns Hopkins School of Medicine to talk about her career and the research of her laboratory on mechanisms of neuroinflammation in disease, especially during HIV infection. Hosts: and Guest: y Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/35707245

Immune 89: Misplaced antibodies and foreign food foes 02/26/2025

Immune 89: Misplaced antibodies and foreign food foes Immune discusses how non-neutralizing antibodies can still be protective…intracellularly, and a technically innovative paper that uses Lipstic to label antigen-presenting cells responsible for gut tolerance to food antigens. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode protect against CCHFV (Nat Comm) APC-T cell interactions drive (Science) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv /episode/index/show/immune/id/35429295

Immune 88: Bespoke antibodies and stinging erythropoiesis 01/29/2025

Immune 88: Bespoke antibodies and stinging erythropoiesis Immune describes the use of bespoke antibodies to characterize immune cell populations in cave nectar bats, and co-option of retrotransposons to activate hematopoietic stem cells and erythropoiesis. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode Immune cells in (Cell Rep) Cave nectar (J Am Asso Lab An Sci) Retrotransposons (Science) (Immunity) on Immune 88 Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv /episode/index/show/immune/id/35071440

Immune 87: When the immune system misbehaves 01/14/2025

Immune 87: When the immune system misbehaves Immune discusses basophils as regulators of of lung inflammation over space and time, and neoself-antigens as the primary target for autoreactive T cells in human lupus. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode promote asthma (J Exp Med) Basophils regulate (J Exp Med) Neoself antigens are (Cell) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv /episode/index/show/immune/id/34852350

Immune 86: Where did the SARS-CoV-2 antibodies go? 11/26/2024

Immune 86: Where did the SARS-CoV-2 antibodies go? Immune explains how distinct olfactory mucosal macrophage populations mediate neuronal maintenance and pathogen defense, and failure to establish durable SARS-CoV-2-specific plasma cells in the bone marrow long-lived compartment after mRNA vaccination. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode , neuronal maintenance, and pathogen defense (Mucos Immunol) after SARS-CoV-2 mRNA vaccination (Nat Comm) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv /episode/index/show/immune/id/34167140

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