Immune 93: Macrophages managing memory B cells Vincent and Cindy discuss differences between MPox-specific T cell responses following infection and vaccination, and lymph node macrophage control of memory B cell localization and trafficking that might be important for choosing which arm to get a vaccine. Hosts: and Subscribe (free): , , Become a of Immune! Links for this episode Different infection or vaccination (Nat Comm 2025) responses after vaccination (Cell 2025) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected] Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/37080415
Immune Booster #13 Microbiome and regulation of gut inflammation with Justin WilsonFrom the 2024 Society for Leukocyte Biology meeting, Cindy and Brianne sit down with Justin Wilson to talk about how he got into research and his more recent studies on innate immune sensors and the interaction between the gut microbiome and inflammation related to inflammatory bowel disease and cancer. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Links for this episode Francisella tularensis defenses (Infect Immunity) AIM2 s cancer (Nature Med) NLRP12 regulates (Cell Host Microbe) Oral connection (Microbiol Mol Bio Rev) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to [email protected] Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/36693660
Immune 92: Gut symbiont breaks antibody Steph talks about identification of gut bacteria that can digest protective mucosal antibodies and Vincent covers a new paper on Zika virus that implicates fetal phagocytes in brain invasion, which may provide insight into the devastating microcephaly outcome of infection during pregnancy. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode Gut bacteria (Science) Contribution of fetal mononuclear (Cell) discusses Zika and brain slice infection model. Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected] Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/36692420
Immune Booster #12: Innate immunity to Archaea with Holger HeineFrom the 2024 Society for Leukocyte Biology meeting, Immune talks with Holger Heine about the discovery of immune recognition of bacterial lipopolysaccharide and innate immunity to organisms within the kingdom Archaea. Hosts: and Guest: Become a of Immune! Links for this episode TLR8 recognizes human (Front Immunol) The for health and disease (FEBS) Structural insights into mimetics (Nature Comm) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to [email protected] Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/36524930
Immune 91: People, parasites, plagues, and podcastsImmune talks with David Peterson and Kim Klonowski from the University of Georgia about their careers, their People, parasites, and plagues podcast, placental malaria immunity, and and how interferons in the thymus affect T cell repertoire selection. Hosts: , , , and Guests: and Subscribe (free): , , Become a of Immune! Links for this episode podcast protein-specific immunity (Trends in Parasitology) affects T cell repertoire selection (Science Immunology) Dickson Despommier’s book Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected] Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/36073595
Immune Booster #11 Immunity to Fungi with Amy HiseFrom the 2024 Society for Leukocyte Biology meeting, Immune talks with Amy Hise about her career in science, her current research using mouse models for investigating fungal immunity and navigating the challenges of being a mom in science. Hosts: and Guest: drugs to treat Candida fungal infection is y Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/36057955
Immune 90: Immunology of Injury Immune 90: Immunology of Injury March 25, 2025 From the 2024 Society for Leukocyte Biology meeting at Michigan State University, home of the Spartans, Immune’s Cindy and Brianne talk with Liz Kovacs and Jim Lederer about their careers, dirty mice, old mice, and immunity during trauma. Hosts: and Guests: and Subscribe (free): , , Become a of Immune! Links for this episode Jim Lederer’s and Liz Kovacs’s and Paper on use of also known as natural immune mice Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected] Information on this podcast should not be construed as medical advice. /episode/index/show/immune/id/35712985
Immune Booster #10 HIV in the brain with Amanda Brown Immune Booster #10 HIV in the brain with Amanda Brown March 18, 2025 From the The Society for Leukocyte Biology 2024 conference at Michigan State University, Cindy and Brianne sit down with Amanda Brown from Johns Hopkins School of Medicine to talk about her career and the research of her laboratory on mechanisms of neuroinflammation in disease, especially during HIV infection. Hosts: and Guest: y Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/35707245
Immune 89: Misplaced antibodies and foreign food foesImmune discusses how non-neutralizing antibodies can still be protective…intracellularly, and a technically innovative paper that uses Lipstic to label antigen-presenting cells responsible for gut tolerance to food antigens. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode protect against CCHFV (Nat Comm) APC-T cell interactions drive (Science) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/35429295
Immune 88: Bespoke antibodies and stinging erythropoiesisImmune describes the use of bespoke antibodies to characterize immune cell populations in cave nectar bats, and co-option of retrotransposons to activate hematopoietic stem cells and erythropoiesis. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode Immune cells in (Cell Rep) Cave nectar (J Am Asso Lab An Sci) Retrotransposons (Science) (Immunity) on Immune 88 Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/35071440
Immune 87: When the immune system misbehavesImmune discusses basophils as regulators of of lung inflammation over space and time, and neoself-antigens as the primary target for autoreactive T cells in human lupus. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode promote asthma (J Exp Med) Basophils regulate (J Exp Med) Neoself antigens are (Cell) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/34852350
Immune 86: Where did the SARS-CoV-2 antibodies go?Immune explains how distinct olfactory mucosal macrophage populations mediate neuronal maintenance and pathogen defense, and failure to establish durable SARS-CoV-2-specific plasma cells in the bone marrow long-lived compartment after mRNA vaccination. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode , neuronal maintenance, and pathogen defense (Mucos Immunol) after SARS-CoV-2 mRNA vaccination (Nat Comm) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/34167140
Immune 85: Immune trade-offsImmune explores the immunological diversity in the upper airway, including memory B and T cells and germinal center B cells, and how chronic infection with Plasmodium parasites leads to development of B cell cancers. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode Immune memory diversity in (Nature) How Plasmodium infection (Cell) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/33671212
Immune 84: Gender-affirming therapy and immune responses with Petter BrodinPetter Brodin joins Immune to discuss immune system adaptation in individuals assigned female sex at birth and undergoing gender affirming testosterone therapy (trans-men). Hosts: , , , and Guest: Subscribe (free): , , Become a of Immune! Links for this episode Petter Brodin on Gender-affirming (Nature) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/33190962
Immune Booster #9: Autoimmune diseases with Mark ShlomchikFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with Mark Shlomchik to talk about his career and the research of his laboratory on systemic autoimmune diseases, long-lived B cell immunity, and immunopathogenesis. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32993272
Immune Booster #8: Immunology, metabolism, and exercise physiology with Heather CaslinFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Heather Caslin to talk about her training and the research of her laboratory on how diet and exercise affect innate immune cells in health and disease. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32866622
Immune 83: Immune cells eating other cellsImmune discusses two stories of immune cells eating other cells: microglia engulfing brain neurons to shape cortical development and behavior, and mast cells trapping neutrophils to increase their functional and metabolic fitness. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode Microglia shape (Cell) by mast cells (Cell) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/32733702
Immune Booster #7: Emerging viruses with David MartinezFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with David Martinez to talk about his career, the research of his laboratory on viral pathogens of global health importance, and his advice to be persistent and enjoy the journey. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32661337
Immune Booster #6: From Ghana to heat shock with Robert BinderFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Robert Binder to talk about his career, the research of his laboratory on the role of heat shock proteins in cancer immunosurveillance, and the importance of inspiring students as early as possible to think about science. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32561857
Immune Booster #5: Infections and the gut microbiome with Rafael PolidoroFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with Rafael Polidoro to talk about his career, the research of his laboratory on how the gut microbiome modulates the local and systemic immune responses during infections. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32452127
Immune 82: Bat antibodies are hotImmune reviews the local and systemic responses after human SARS-CoV-2 challenge infection, and how bat antibodies display elevated antigen binding strength and diversity at higher temperatures that are characteristic of flight. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode Responses to human (Nature) Temperature-sensitivity of (Nat Comm) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/32343427
Immune Booster #4: Human autoimmunity with Jane BucknerFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with Jane Buckner to talk about her career, and the research of her laboratory on mechanisms by which regulation of the adaptive immune response fails or is overcome in the setting of human autoimmunity. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32249757
Immune Booster #3: NKT cells and cancer, and DEI in research with Tonya WebbFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Tonya Webb to talk about her career, the role of NKT cells in cancer, and her efforts to ensure diversity, equity, and inclusion in research. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32149897
Immune Booster #2: Sex differences in immune responses with Michal TalFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne meet up with Michal Tal to talk about her career, sex differences in immune responses, and how one giant mouse uterus changed the trajectory of her research career. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/32056472
Immune Booster #1: From bench to bedside to beat HIV with Luis MontanerFrom the American Association of Immunologists 2024 conference in Chicago, Cindy and Brianne where meet up with Luis Montaner to talk about his career and his research on boosting the immune system to combat viral diseases or cancer progression. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Links for this episode in research (Res Involv Engag) Susceptibility to during ART (AIDS) experience (J Immunol) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to [email protected] Content in this podcast should not be construed as medical advice. /episode/index/show/immune/id/31982567
Immune 81: T cells and tolerance with Joseph Larkin IIIImmune travels to Chicago for the American Association of Immunologists conference where they meet up with Joseph Larkin III to talk about his career and his research on the contribution of T lymphocyte subsets and functions in maintaining tolerance. Hosts: and Guest: Subscribe (free): , , Become a of Immune! Links for this episode in immunity and autoimmunity (J Immunol Res) COVID-19 booster enhances (Front Nutr) SARS-CoV-2 after maternal immunization (J Perinatol) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/31868322
Immune 80: Intranasal neomycin; sex hormones and skin immunity; and maternal diet and infant microbiomesImmune presents three stories: intranasal neomycin and antiviral immunity, sexual dimorphism in skin immunity, and maternal diet changes infant microbes that alter gut DC responses and respiratory health. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode Intranasal (PNAS) Sexual dimorphism in (Science) Maternal diet and (Immunity) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/31484642
Immune 79: Spa therapy for the immune systemImmune explains how antibody-mediated depletion of myeloid-hematopoietic stem cells in aged mice restores characteristic features of a more youthful immune system, including increasing common lymphocyte progenitors, naive T cells and B cells, while decreasing age-related markers of immune decline. Hosts: , , and Subscribe (free): , . , Become a of Immune! Links for this episode Depleting My-HSC (Nature) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/31471777
Immune 78: Tolerance and tolerating many vaccinesImmune discusses responses in a COVID hypervaccinated individual, synthetically glycosylated antigens for the antigen-specific suppression of established immune responses, gut bacteria–derived serotonin promotes immune tolerance in early life, and mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge. Hosts: , , , and Subscribe (free): , . , Become a of Immune! Links for this episode Adaptive immune responses preserved in (Lancet) Synthetically glycosylated antigens for of established immune responses (Nat Biomed Eng) Gut bacteria–derived serotonin in early life (Sci Immunol) Immune correlates of viral control after in adults (Sci Immunol) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/30552963
Immune 77: Squeezing the most killing out of neutrophilsImmune reviews research showing that the migration of neutrophils between endothelial cells activates bactericidal function via mechanosensing. Hosts: , , , and Subscribe (free): , . , Become a of Immune! Links for this episode activates neutrophil killing (Immunity) Time stamps by . Thanks! Music by Steve Neal. Immune logo image by Send your immunology questions and comments to [email protected]/episode/index/show/immune/id/30135188
