Oncology Overdrive

In this podcast by Healio, host Shikha Jain, MD, FACP, covers modern day health care in an ever-evolving world. Through interviews with experts, Jain explores hot topics in oncology and beyond.

Equitable Representation in Clinical Trials with Nadine Spring, PhD 04/24/2025

Equitable Representation in Clinical Trials with Nadine Spring, PhD In this episode, host Shikha Jain, MD, speaks with Nadine Spring, PhD, about the importance of DEI in clinical care, driving positive social change forward and more. • Welcome to another exciting episode of Oncology Overdrive 0:14 • About Spring 0:20 • The interview 1:00 • Tell me about the journey that got you to where you are today? 1:18 • Can you tell me more about and your role there? 5:11 • Why does diversity and equitable representation in clinical trials and care matter? 6:23 • What is , and what do you hope to achieve with the work you are doing through this organization? 8:28 • Do you think that current funding challenges will impact these initiatives over the next few years? 11:37 • Do you feel like you will have to re-imagine or modify how you describe the work you are doing to help people understand its impact? 12:11 • How do you suggest clinicians and institution leaders get involved in raising awareness and increasing diversity in clinical trials? 12:48 • What do you say to people who are doing this work and are getting frustrated or burnt out? How do you keep them motivated? 16:37 • What keeps you motivated to continue this work? 17:56 • When you talk to people about clinical trials, how do you address patients’ mistrust or fear of the unknown? 19:04 • If someone could only listen to the last few minutes of this episode, what would you want listeners to take away? 23:58 • How to contact Spring 25:15 • Thanks for listening 25:59 Nadine Spring, PhD, has spent her career fighting for more inclusive and diverse representation in clinical research. She is a recognized leader in advancing health equity, particularly through her work at , which advocates for the inclusion of underserved populations in clinical trials. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Spring can be reached at or via email . Disclosures: Jain and Spring report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/36292640

Finding fulfillment in medicine: Physician side gigs and exploring new avenues, with Navin Goyal, MD (Crossover with Physicianary) 03/27/2025

Finding fulfillment in medicine: Physician side gigs and exploring new avenues, with Navin Goyal, MD (Crossover with Physicianary) In this special crossover episode with Physicianary, guest Navin Goyal, MD, and Physicianary host, Hansa Bhargava, MD, discuss side gigs in the health care space, encourage physicians to explore their fields of interest and talk about his book, Physician Underdog. • Intro 0:28 • Navin Goyal, MD 0:35 • You have done a lot to help Medicaid patients with your venture capital group, OFFOR Health. Can you tell us about that? 1:25 • What was the driver of your venture capital group? Was it access to care? 3:21 • Tell us about your interest in health equity and access to care? What happened next. 6:28 • Tell us about your book, . Did the book come before, during or after your journey with your venture capital group? 7:55 • What is your advice to physicians and health care workers who feel burnt out and unfulfilled in their career path? 11:54 • Bhargava and Goyal discuss change and adapting to changes in career paths. 14:57 • Bhargava and Goyal discuss the difference between careers in health care and other professions that are likely to pursue new avenues. 16:42 • There are plenty of physicians out there looking for side gigs. What is your advice to physicians and health care workers who want to explore other avenues and side gigs? 19:29 • How do you do it all? 22:10 • Thanks 24:42 Navin Goyal, MD, is a venture capitalist, entrepreneur, physician and author—driven by his passion for human-centered leadership. He is the co-founder and managing partner at LOUD Capital, specializing in early-stage investments in healthcare and technology startups. Goyal is also co-founder of OFFOR Health, a venture-backed startup that provides mobile anesthesia services for pediatric patients on Medicaid, and Beyond Physician, an online learning management platform and job marketplace to enable physicians to learn new skills, get contract work and grow their thought leadership. His journey and insights are captured in his book, . We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Follow Dr. Bhargava on X and on Instagram . Follow Goyal on Instagram , X , and and visit his website: . Disclosures: Bhargava and Goyal report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/35885525

Pioneering Changes in Patient Advocacy with Kimberly Richardson 02/20/2025

Pioneering Changes in Patient Advocacy with Kimberly Richardson In this episode, host Shikha Jain, MD, speaks with Kimberly Richardson about driving changes in patient advocacy efforts, the importance of including DEI in cancer research and clinical trials and more. • Welcome to another exciting episode of Oncology Overdrive 0:14 • About Richardson 0:20 • The interview 1:15 • How did you get to where you are today as such a leader and advocate? 1:56 • Did you feel welcomed into this space when you started doing your advocacy work, or did you feel like it was an uphill battle? 5:12 • Jain and Richardson on how physicians and patient advocates can come up with solutions that coincide with the transformation of what advocacy work has become. 8:23 • What are the different ways people can be patient advocates? 10:59 • Jain and Richardson on research advocacy and the power of the ripple effect when it comes to how this work impacts patients. 15:45 • Jain and Richardson on how physician and patients can collaborate to overcome institutional challenges with timing of visits and quality of care. 19:11 • Richardson and Jain on educating patients in underrepresented communities on research and policy changes that will lead to more diversity in clinical trials. 24:21 • If you could look back one year from now, what do you hope your research grant accomplishes? 30:00 • If someone could only listen to the last few minutes of this episode, what would you want listeners to take away? 32:00 • How to contact Richardson 32:33 • Thanks for listening 33:27 Kimberly Richardson is a survivor of ovarian cancer and early stage, triple positive breast cancer. Kimberly has founded the , a 501 (c)3 nonprofit organization that creates partnerships between Black cancer patients and the medical and scientific communities on issues of health equity, patient inclusion and clinical trials participation. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Richardson can be found on Bluesky under Black Cancer Collaborative and on . Disclosures: Jain and Richardson report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/35363155

Survivorship and Visual Storytelling with Anna Rathkopf 02/06/2025

Survivorship and Visual Storytelling with Anna Rathkopf In this episode, host Shikha Jain, MD, speaks with Anna Rathkopf about the mental and physical toll of cancer treatment and survivorship, using photography to connect with patients and caregivers and more. • Welcome to another exciting episode of Oncology Overdrive 0:14 • About Rathkopf 0:20 • The interview 1:23 • How did you get into storytelling through photography around your cancer diagnosis and your caregiver experience? 1:46 • How did you navigate questions and challenges surrounding fertility during the first five years of your diagnosis? 4:07 • On top of everything else going on in your life at the time, how did your decision to document your treatment become part of your plan? Why was it so important for you to do in that moment? 7:50 • Did photography help you feel like you had some control in your life? 10:45 • Overall, how did this impact your mental health along with your physical health? 11:17 • What were you doing from a photojournalistic standpoint prior to your diagnosis? How did that prepare you for this next step in what you have created? 14:46 • How did your partner’s caregiving responsibilities incorporate into your photography? 16:48 • Jain and Rathkopf on the sacrifices caregivers make. 19:53 • If you had to give advice to someone going through the initial time after cancer diagnosis, caregiver or patient, what would you say you would do the same or differently? 21:29 • What do you suggest loved ones do or say to help patients and caregivers? 24:49 • What was the transition into survivorship like for you after the first five years? How did that change your mentality? 27:24 • If someone could only listen to the last few minutes of this episode, what would you want listeners to take away? 33:34 • How to contact Rathkopf 34:20 • Thanks for listening 35:22 Anna Rathkopf is an award-winning photographer whose work focuses on empathy, health, and identity. She is the author of , a poignant exploration of the realities of cancer under 50. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Rathkopf can be found on Instagram . Purchase on Amazon or on the website . For more from the Rathkopfs: Check out photos and from their installation at exhibition at Montefiore Einstein through April 18, 2025. Disclosures: Jain and Rathkopf report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/35174700

Diversity and Development in Hematology with Belinda Avalos, MD 01/23/2025

Diversity and Development in Hematology with Belinda Avalos, MD In this episode, host Shikha Jain, MD, speaks with ASH president, Belinda Avalos, MD, about the importance of DEI practices in medicine, leading molecular medicine developments and more. • Welcome to another exciting episode of Oncology Overdrive 0:14 • About Avalos 0:18 • The interview 1:18 • How did you know you know you wanted to be a hematologist and how did you end up in this space doing the work you’re doing now? 1:47 • Jain and Avalos on the innovations and patient relationships in the field of HemOnc that drive physician interest. 3:25 • What drove your passion to get involved in DEI and equitable care in medicine? 5:08 • Jain and Avalos on diversity in clinical trials. 7:48 • Jain and Avalos on the importance of multidisciplinary approaches to patient care. 9:08 • What do you see as the biggest barriers to driving change in this space? How can we actually make changes that will result in real-world transformation? 10:11 • Tell me about the work that you do in the spaces of women in hematology and medicine. 11:25 • What types of things should we be doing to drive gender equity changes in medicine? 13:40 • Do you feel hopeful about where we are going with the changes being driven by societies like ASH? 15:24 • What else excites you about hematology and the innovation in the field now? 17:02 • What are the biggest transformations we are going to see in hematology over the next decade? 23:26 • Where will you be focusing your time moving forward? 27:53 • If someone could only listen to the last few minutes of this episode, what would you want listeners to take away? 29:16 • How to contact Avalos 30:15 • Thanks for listening 30:44 Belinda R. Avalos, MD, is the American Society of Hematology 2025 president, and is a professor of medicine and a senior advisor to the president of Atrium Health Levine Cancer. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Avalos can be reached by contacting ASH at . Disclosures: Jain and Avalos report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/34970195

The Role of Machine Learning in Clinical Trials with Damon Rasheed 12/30/2024

The Role of Machine Learning in Clinical Trials with Damon Rasheed In this episode, host Shikha Jain, MD, speaks with Opyl co-founder Damon Rasheed about using machine learning to better predict clinical trial outcomes, handling ethical concerns surrounding AI in health care and more. • Welcome to another exciting episode of Oncology Overdrive 0:14 • About Rasheed 0:20 • The interview 0:58 • How did you end up in the AI-powered medicine and clinical trials? 1:48 • What is Opyl, and what is TrialKey? 3:54 • Is TrialKey predominantly based in Australia or is it available outside of Australia as well? 5:34 • Can you explain how machine learning works in order to create these outcomes? 6:11 • How do you see people utilizing this tool in the future based on what you have already seen? 8:30 • How have others received this? What is the feedback you have gotten surrounding what people are excited and concerned about with this technology? 10:50 • Does this type of product take into account the issue of diversity in clinical trials? 13:41 • What’s next for expanding Opyl and TrialKey? 14:27 • What keeps you excited and motivated to continue working in this space? 15:28 • If someone could only listen to the last few minutes of this episode, what would you want listeners to take away? 19:35 • How to contact Rasheed 20:16 • Thanks for listening 20:54 Damon Rasheed is a serial entrepreneur recognized for his groundbreaking ventures and deep expertise in machine learning and big data. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Rasheed can be reached at or . Disclosures: Jain reports no relevant financial disclosures. Rasheed reports TrialKey is powered by Opyl Limited, which is a publicly listed company operating on the ASX. /episode/index/show/oncologyoverdrive/id/34655970

Highlights from ASH 2024 (Meeting Mic Re-Release) 12/19/2024

“Back to the Future”: Developments in Immunotherapy with David Gandara, MD 12/12/2024

“Back to the Future”: Developments in Immunotherapy with David Gandara, MD In this episode, host Shikha Jain, MD, speaks with David Gandara, MD, about how ctDNA and CAR-T cell therapies are transforming precision medicine, the importance of patient reported outcomes and more. • Welcome to another exciting episode of Oncology Overdrive 0:14 • About Gandara 0:19 • The interview 1:02 • Can you tell me a little more about what you are working on now? 1:25 • How did you get engaged with the community in Hawaii? 6:30 • What do you think is going to happen with ctDNA moving forward? 8:29 • Can you utilize ctDNA and minimal residual disease information to determine how long patients need to be on adjuvant therapy? 11:42 • How did you get into the ctDNA space? 15:06 • How do you see AI transforming health care beyond providing patients with more information and taking more ownership of their health? 18:28 • Can you tell us more about how a second opinion clinic works? How did this type of clinic develop and become part of what you do? 23:17 • What are some of your predictions as to what will happen in oncology care over the next ten to twenty years? 29:00 • If someone could only listen to the last few minutes of this episode, what would you want listeners to take away? 37:30 • How to contact Gandara 38:47 • Thanks for listening 39:10 David Gandara, MD, is a clinician-scientist and lung cancer specialist internationally recognized for his expertise in thoracic cancers, cancer drug development and biomarker development. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Dr. Gandara can be reached via email . Disclosures: Jain reports no relevant financial disclosures. Gandara reports institutional research grants from Astex, Amgen and Genentech; institutional consulting for AstraZenica, Exact Sciences, Genentech, Guardant Health, IO Biotech and Oncohost; consulting for Adagene, Henlius USA, Foundation Medicine and Sanofi; serves on the advisory board of Abbvie, Janssen, Merck, Mirati, Regeneron and Revolution Medicine. /episode/index/show/oncologyoverdrive/id/34363955

Enhancing Clinical Trial Enrollment with Michel van Harten, MD 11/27/2024

Enhancing Clinical Trial Enrollment with Michel van Harten, MD In this episode, host Shikha Jain, MD, speaks with Michel van Harten, MD, about creating better information systems for physicians and patients, how shared decision-making can improve drug development and more. • Welcome to another exciting episode of Oncology Overdrive 0:14 • About van Harten 0:20 • The interview 1:00 • What was your journey to becoming a physician and beyond to where you are now? 1:24 • How did you learn the necessary skills to be an exceptional leader in this space? 2:51 • How many years were you a practicing physician for? 3:53 • What does myTomorrows do, and what drew you to this type of work? 4:54 • Where is this service available? 7:19 • Jain and van Harten on the challenges patients face surrounding eligibility for clinical trials. 8:36 • Where do you see this going down the line? 10:05 • Has your company looked into how to these services can impact diversifying clinical trial enrollment? 12:04 • What are some challenges your company has faced? 13:50 • How quickly do you think growth will accelerate in this space? 15:26 • How will this work and resource have major impacts on drug development in a more accelerated way than in the past? 16:11 • From the patient-facing side, have you faced any challenges concerning patients’ willingness to be enrolled in clinical trials? 18:22 • What is next for you, and where do you see yourself in twenty years? 19:13 • Do you have any concerns about AI in health care? […] What should we be aware of when utilizing AI in this space? 19:45 • Jain and van Harten on the challenges and setbacks that come from outdated and inaccurate clinical trial databases. 21:35 • If someone could only listen to the last few minutes of this episode, what would you want listeners to take away? 23:50 • How to contact van Harten 24:28 • Thanks for listening 25:17 Michel van Harten, MD, is the CEO of myTomorrows. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Michel van Harten can be reached via email . Disclosures: Jain and van Harten report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/34178035

The Data Behind Precision Medicine with Melody Harris 11/21/2024

Highlights from 2024 World Conference on Lung Cancer (Meeting Mic Re-Release) 11/14/2024

Health Care Advocacy During Elections with Alice Chen, MD 10/31/2024

Health Care Advocacy During Elections with Alice Chen, MD In this episode, host Shikha Jain, MD, speaks with Alice Chen, MD, about the impact of misinformation and disinformation during elections, the health care issues on the 2024 ballot and more. Content warning: This episode discusses sensitive topics surrounding women’s health and reproductive rights. • Welcome to another exciting episode of Oncology Overdrive 0:14 • About Chen 0:32 • The interview 1:38 • How did you get into the public health and advocacy spaces? 1:58 • Have you seen an evolution in medical professionals becoming more involved in politics and advocacy? 5:08 • How has misinformation impacted politics, health care, policy and the election? 7:25 • As health care workers, how do we address misinformation to help our communities and patients? 10:51 • Do you feel that health care workers should use social media for this type of advocacy work? 15:26 • Is there more of a need for health care workers to be doing this work now than it was pre-social media? 18:14 • Jain and Chen on how discussions around politics have changed in the last decade. 26:05 • What are the major health care topics being discussed and impacted by this upcoming election? Why is health on the ballot? 28:33 • Jain and Chen on women’s health and why it matters in this election. 30:58 • What are health care workers doing to promote advocacy? 37:05 • If you could summarize this episode in one minute, what would you want listeners to take away? 45:36 • How to contact Chen 46:11 • Thanks for listening 46:53 Alice T. Chen, MD, is a mom, physician and national leader in public health, physician advocacy and community organizing. She serves as the co-chair of the board of directors of Health Care Without Harm. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Chen can be reached on X and on . Disclosures: Jain and Chen report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/33702792

Advocating for Patient Access with Amita Patnaik, MD, FRCPC 10/17/2024

Developing Products for Cancer Care with Annmarie Ison 10/03/2024

Entrepreneurship in Biotech with Brian Fiske 09/19/2024

Women in medicine roundtable, Part 2: On empowerment and advocacy 09/05/2024

Women in medicine roundtable, Part 2: On empowerment and advocacy On this special edition episode, Shikha Jain, MD, with Physicianary’s Hansa Bhargava, MD, and Mend the Gap’s Dagny Zhu, MD, discuss the evolution of empowering yourself and others and advocacy with a panel of guests. • Intro 1:01 • What does it mean to empower women in medicine, and what are the ways that we can really empower others to achieve the things that they may not see for themselves? 2:39 • What are some ways in which you have empowered or hope to empower women in medicine? Are there tips or skills that have worked well? 5:43 • How have you been empowered by others, or have helped others find their voices? 8:38 • Do you agree that the conversation is changing toward a cultural shift in empowerment for women in health care? 13:53 • What are some challenges facing advocacy and empowerment? What do you do when your advocacy work is not being received or it is a struggle to speak up for someone? 18:40 • Emphasizing the importance of communication in advocacy work. 24:00 • Intro to Physicianary’s part 3 on physician burnout and work-life balance. 24:16 • Thanks for listening 25:00 Vineet Arora, MD, MAPP (NAM), is a Herbert T. Abelson professor of medicine, vice dean of education in the biological sciences division and dean for medical education at the University of Chicago Pritzker School of Medicine. She is also an elected member of the National Academy of Medicine. She is a founding member of the 501c3 Women of Impact and advisor to the Women in Medicine Summit. Jennifer Bepple, MD, MMCi, is a double board-certified physician in urology and informatics. She is a member of the American Telemedicine Association, American Urologic Association and American Medical Informatics Association and holds a certification from the American Board of Telehealth and the American Board of AI in Medicine. Hansa Bhargava, MD, is Healio's chief clinical strategy and innovation officer. Listen to her Healio podcast, . Shikha Jain, MD, FACP, is a board-certified hematology and oncology physician. She is a tenured associate professor of medicine in the division of hematology and oncology, the director of communication strategies in medicine and the associate director of oncology communication & digital innovation at the University of Illinois Cancer Center in Chicago. Mara Schenker, MD, FACS, FAOA, is an orthopedic trauma surgeon at Grady Memorial Hospital. She is double board certified in orthopedic surgery and clinical informatics. She serves as the chief of orthopedics and associate chief medical information officer. She is an associate professor of orthopedics at Emory University School of Medicine. She serves on multiple boards for medical and digital technology advisory and sits on major national committees for the American Academy of Orthopaedic Surgeons, AAMC, American College of Surgeons and the Orthopaedic Trauma Association. Dagny Zhu, MD, is a cornea, cataract and refractive surgeon and medical director and partner at NVISION Eye Centers in Rowland Heights, CA. She can be reached on X . We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Disclosures: The hosts and guest report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/32908237

Celebrating 100 episodes with the original Dr. Jain, my dad! 08/22/2024

Celebrating 100 episodes with the original Dr. Jain, my dad! In this special 100th episode, host Shikha Jain, MD, speaks with her father, Krishna Jain, MD, about work-life balance pertaining to private practice, improving a fragmented health care system and more. • Welcome to another exciting episode of Oncology Overdrive 1:18 • About Krishna Jain 1:27 • The interview 2:27 • How did you end up in the United States? What was your journey to becoming a world-renowned vascular surgeon? 2:44 • What was it like being a resident back then, especially as someone who came from abroad? 7:30 • After training, why didn’t you go back to India? 10:12 • Shikha Jain on how her father inspired her passion for research and mentorship. 13:19 • Why did you choose to go into private practice, and how did you build your practice and become a leader in this space? 15:18 • The Jains on the importance of being present for and supporting family. 19:16 • How did your entrepreneurial life start? 23:55 • What do your limb preservation centers do? 27:33 • What are some things that need to be done to improve our fragmented health care system? 29:45 • What led you found the ? 34:16 • How did you end up deciding to go to Kalamazoo, MI instead of going back to India? 39:11 • What are most proud of in your career? 41:28 • What do you want to share with the next generation of surgeons and physicians? 44:07 • The Jains on their relationship growing up and now. 45:44 • If someone could only listen to the last minute of this episode, what would you want them to take away? 47:48 • How to contact Jain 48:48 • Thanks for listening 50:43 Krishna Jain, MD, is a vascular surgeon who has been intimately involved in the growth of office based endovascular centers throughout the country since 2007. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Krishna Jain can be reached via email . Disclosures: Jain reports no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/32690527

Tackling Cancer with Olympic Gold-Medalist Kikkan Randall (Re-Release) 08/08/2024

Tackling Cancer with Olympic Gold-Medalist Kikkan Randall (Re-Release) In this special throwback episode, Shikha Jain, MD, talks with Olympic champion Kikkan “Kikkanimal” Randall, about how her positive attitude and athlete mentality have helped her navigate a breast cancer diagnosis and treatment, valuable advice for both oncologists and patients and more. • Intro 1:44 • About Randall 1:58 • The interview 3:22 • Tell us a bit about you. Who are you? How did you get to where you are and how did you decide you wanted to be a part of the U.S. Olympic cross-country ski team? 3:51 • How were you diagnosed? 6:12 • How old were you when you first realized that you had this pebble in your breast? 7:33 • What type of mentality is it that makes you such a phenomenal Olympic athlete that you were able to translate into this taking charge of your health and taking charge of your cancer as you move forward? 9:20 • What was the best way for you to cope as you felt this loss of control going through your treatment in certain times? 12:09 • What did you do to prepare for your clinic visits when you were trying to advocate for yourself? 16:17 • Can you talk more about the you kept during treatment? 17:55 • How did you navigate the disease with your son? 21:50 • How long do they recommend for you to wait to try again (to conceive)? Did you have those conversations? 26:17 • Do you feel like you are mentally approaching this period of your post-cancer care or your post-treatment time? 29:58 • Randall running a marathon following the completion of her treatment 32:07 • How did you get involved with and , and what exactly do they do? 38:08 • Did the way that you participate in advocacy change after you were diagnosed with cancer? 42:46 • One thing you wish oncologists knew when they are treating patients with any kind of cancer, and one thing patients should know if they’re newly diagnosed? 48:09 • How to find Randall 50:26 • Thanks for listening 51:58 Kikkan Randall is an Olympic champion, active mom, cancer fighter and “Get-Activist.” We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Randall can be reached at . Disclosures: Jain reports no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/32496477

Machine Learning in Cancer Care with Shyam Natarajan, PhD 07/25/2024

Machine Learning in Cancer Care with Shyam Natarajan, PhD In this episode, host Shikha Jain, MD, speaks with Shyam Natarajan, PhD, about machine learning in cancer research and testing, using technological innovation to address disparities in health care trials and more. • Welcome to another exciting episode of Oncology Overdrive 1:17 • About Natarajan 1:22 • The interview 2:10 • How did you get into the medical technology space? 2:29 • Can you explain what machine learning means? 4:37 • How did you end up co-founding Avenda Health? 7:18 • Do you think that this type of technology is replicable in other disease types as well? […] Where else do you see this being a benefit? 9:53 • When you think about AI, what are the other applications for this type of technology outside of oncology? 11:24 • How do you respond to concerns that AI is becoming too sentient or independent? 12:50 • What are the checkpoints we need to put in place to make sure that biases in AI algorithms do not become the norm? 16:21 • Do you have ways to predict who would benefit from these types of technology, and can you categorize patients into who is appropriate for trialing these technologies? 19:44 • Is there a way to utilize this technology to address disparities in health care? 22:04 • Have you found that there are specific things that make it harder to enroll patients in these particular clinical trials? How do you navigate those? 24:47 • If you had a crystal ball that could see fifty years into the future, where do you see all of this technology going? 27:28 • If someone could only listen to the last few minutes of this episode, what would you want them to take away? 30:56 • How to contact Natarajan 31:31 • Thanks for listening 32:22 Shyam Natarajan, PhD, is the co-founder and CEO of Avenda Health, a medtech company focused on improving outcomes for the one in seven men at risk for prostate cancer. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Natarajan can be reached at or via LinkedIn. Disclosures: Jain and Natarajan report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/32289622

Breast Cancer Drug Development with Komal Jhaveri, MD 07/11/2024

Cancer Clinical Trials with David Cosgrove, MD 06/27/2024

Cancer Clinical Trials with David Cosgrove, MD In this episode, host Shikha Jain, MD, speaks with David Cosgrove, MD, about implementing real-world utilization of clinical trials, the importance of diversity in clinical trials and more. • Welcome to another exciting episode of Oncology Overdrive 1:17 • About Cosgrove 1:26 • The interview 2:54 • How did you make your way from Ireland to Portland, Oregon? 3:18 • As a fellow GI oncologist, what are you excited about in the cancer research space? 6:13 • How can we realistically address disparities in cancer care to deliver the latest breakthroughs to patients? 8:54 • Jain and Cosgrove on the challenges GI cancers experience in terms of delivery of cancer care compared to colleagues in other spaces. 11:22 • What excites you about what’s happening in oncology right now, and where we’re going in this space? 13:30 • How did you end up as medical director at Compass Oncology? 15:15 • What are you specifically working on now, and where do you hope to see it go in the next five years? 17:25 • How do we get more patients from different backgrounds into clinical trials, and why is it important that we do that? 19:05 • Jain and Cosgrove on challenges facing patient guidelines and qualifications for clinical trials. 21:09 • If someone could only listen to the last few minutes of this episode, what would you want them to take away? 23:41 • How to contact Cosgrove 24:45 • Thanks for listening 25:49 David Cosgrove, MD, serves as the medical director of Compass Oncology in Portland, Oregon, and specializes in general adult oncology with advanced subspecialty expertise in gastrointestinal cancers. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Cosgrove can be reached via email . Disclosures: Jain and Cosgrove report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/31912112

Surgical Technology Development with Ananth Ravi 06/13/2024

Surgical Technology Development with Ananth Ravi In this episode, host Shikha Jain, MD, speaks with MOLLI Surgical co-founder and CEO, Ananth Ravi, about inventing surgical technology to provide better patient care, addressing inequities in surgical tool access and more. • Welcome to another exciting episode of Oncology Overdrive 1:15 • About Ravi 1:27 • The interview 2:10 • Tell me about how entered this field and how you ended up founding a company that invents surgical instruments. 2:42 • How did you end up moving from Zambia to Canada? 5:02 • Tell me more about MOLLI Surgical. How is this precision surgery unique from what is already out there? 6:47 • What is your background to help you go from ideation to implementation, and how did you take the steps to make your ideas a reality? 10:31 • How do you address rural and global disparities when it comes to accessing these technologies? 16:12 • In an ideal world, where would you see this technology being utilized, and are there any other technologies that you think will revolutionize this type of care? 19:32 • What else excites you about this space? […] How did you find going from the academic space into this role in the business/corporate space? 22:19 • Jain and Ravi on work-life balance. 25:51 • What’s next for you in the next three to five years? 29:26 • If someone could only listen to the last few minutes of this episode, what would you want them to take away? 30:15 • How to contact Ravi 30:42 • Thanks for listening 31:39 Ananth Ravi is president, CEO and co-founder of MOLLI Surgical. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Ravi can be reached at or via email . Disclosures: Jain reports no relevant financial disclosures. Ravi reports he is president, CEO and co-founder of MOLLI Surgical. /episode/index/show/oncologyoverdrive/id/31714837

Advancements in Biotech with Spiro Rombotis 05/30/2024

Uncovering Innovations with Jennifer Michaelson, PhD 05/16/2024

Innovation in Industry with Sean Bohen, MD 05/02/2024

Innovation in Industry with Sean Bohen, MD In this episode, host Shikha Jain, MD, speaks with Sean Bohen, MD, about how cancer therapies are changing how oncology can be discussed, shifting from clinical to industry work and more. • Welcome to another exciting episode of Oncology Overdrive :58 • About Bohen 1:04 • The interview 1:30 • Tell us about your journey. How did you become an oncologist, and how did you make the transition into working in the pharmaceutical industry? 1:51 • How did you end up at Olema Oncology after working with other pharmaceutical companies? What was your decision-making process to focus on the industry part of your career? 3:44 • Tell us more about what Olema Oncology does and what your role is there. 6:30 • What do you see coming down the pipeline for breast cancer research and innovation? … What do you think Olema will contribute to that space? 8:58 • Bohen and Jain on the ways in which new treatments have resulted in shifting conversations around cancer care and patient quality of life. 12:45 • If someone in fellowship is interested in working in industry, pharmaceuticals or scientific development, what are the most effective ways to get into this space? 18:21 • Jain and Bohen on changing the mindset and misconceptions around moving between clinical, academic and industry work within the field and after fellowship. 20:52 • What do you see happening in the oncology landscape twenty years from now? 25:46 • If someone could only listen to the last two minutes of this episode, what would you want them to take away? 29:19 • How to contact Bohen 30:54 • Thanks for listening 31:52 Sean Bohen, MD, is the President and CEO of Olema Oncology. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X and LinkedIn: and . Follow Dr. Jain on X: . Bohen can be reached at . Disclosures: Jain and Bohen report no relevant financial disclosures. /episode/index/show/oncologyoverdrive/id/31086138

Learning Leadership with Jonathan D. Licht, MD 04/18/2024

Learning Leadership with Jonathan D. Licht, MD In this episode, host Shikha Jain, MD, speaks with Jonathan D. Licht, MD, about becoming and training qualified leaders in the field, challenges facing health care leaders and more. • Welcome to another exciting episode of Oncology Overdrive :58 • About Licht 1:16 • The interview 3:17 • Can you tell us about your journey into hematology-oncology and how you ended up where you are today? 3:58 • How have you found the time and ability to balance and succeed in the research, clinical, translational and leadership parts of your work? 9:05 • What do you suggest to people who are currently trying to get into leadership positions in their early-to-mid career? 12:52 • Do you agree with the sentiment that there are some leaders in the field who are put into positions prematurely or are ineffective? As a leader, how do you address the need for further training of future leaders? 18:39 • What are some of the leadership challenges you have seen in the last several years, and how have you managed to navigate them? 23:20 • How did you use your leadership skills to navigate the first few years of the pandemic, and how are you continuing to navigate delivery of care post-pandemic? 29:23 • Tell me about the process of achieving NCI designation and what it means for your institution. 36:25 • How have you had to navigate state health care legislation and policies challenging reproductive health care? 42:16 • If someone could only listen to the last minute of this episode, what would you want them to take away? 46:13 • How to contact Licht 46:56 • Thanks for listening 48:16 Jonathan D. Licht, MD, is the director of the University of Florida Health Cancer Center. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X, formerly known as Twitter, and LinkedIn: and . Follow Dr. Jain on X, formerly known as Twitter: . Licht can be reached on X, formerly known as Twitter, or via email . Disclosures: Jain reports no relevant financial disclosures. Licht reports consultancy for AstraZeneca and research funding for Epizyme. /episode/index/show/oncologyoverdrive/id/30883513

Global GI Oncology with Aparna Parikh, MD 04/04/2024

Global GI Oncology with Aparna Parikh, MD In this episode, host Shikha Jain, MD, speaks with Aparna Parikh, MD, about cancer and GI malignancies in the global health space, circulating tumor DNA in the field of oncology and more. • Welcome to another exciting episode of Oncology Overdrive :58 • About Parikh 1:07 • The interview 2:08 • What was your path into medicine, cancer care and GI oncology? 2:35 • Tell us about what you do in the global health space and what your thoughts are on colon cancer and GI malignancies in the global health space. 8:07 • Why are we seeing so many more young people being diagnosed with colon cancer in the US and internationally? 12:24 • Do you think US lifestyle and Western diets compared to the rest of the world have contributed to the rise of early colon cancer diagnoses? 15:04 • How can physicians talk about lifestyle, diet and environmental/social determinants of health that impact a cancer diagnosis? 17:52 • Can you provide a brief overview of what is circulating tumor DNA (ctDNA) and liquid biopsy, and how are we using it in this space? 19:44 • Jain and Parikh on ctDNA as an innovation can be transformative in the field of GI oncology. 24:06 • What are your predictions for GI oncology in the next ten to twenty years? 26:06 • If someone could only listen to the last few minutes of this episode, what would you want them to take away? 28:44 • How to contact Parikh 30:57 • Thanks for listening 31:57 Aparna Parikh, MD, is a GI oncologist at the MGH Cancer Center where she directs the colorectal research program and young adults CRC program. She is an associate professor at Harvard Medical School and an international expert in CRC and liquid biopsies. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X, formerly known as Twitter, and LinkedIn: and . Follow Dr. Jain on X, formerly known as Twitter: . Parikh can be reached via email . Disclosures: Jain reports no relevant financial disclosures. Parikh reports equity in C2i Genomics XGenomes Cadex and Parithera. Advisor/consultant for Abbvie, AZ, Bayer, Biofidelity, Checkmate Pharmaceuticals, CVS, Delcath, Eli Lilly, FMI, Guardant, Hookipa, Illumina, Inivata, Mirati, Pfizer, Saga, Seagen, Taiho, Scare Inc, Science For America, and Value Analytics Lab. She receives fees from Up to Date. She has received travel fees from Karkinos Healthcare. She has been on the DSMC for a Roche study and on Steering Committee for Exilixis. She has received research funding to the Institution from BMS, Daiichi Sankyo, Erasca, Genentech, Mirati, Novartis, PMV Pharmaceuticals, Plexxicon, PureTech, Takeda and Syndax. /episode/index/show/oncologyoverdrive/id/30678813

Genomic Testing and Tools with Barnaby Balmforth, PhD 03/21/2024

Genomic Testing and Tools with Barnaby Balmforth, PhD In this episode, host Shikha Jain, MD, speaks with Barnaby Balmforth, PhD, about the evolution of genomics in cancer care, the impact of personalized care tools and more. • Welcome to another exciting episode of Oncology Overdrive :58 • About Balmforth 1:12 • The interview 3:01 • How did you get to where you are today? What drove you to become a leader in this space? 3:45 • What is genomics, and why is genomic analysis important in cancer care? 7:18 • Jain and Balmforth on the evolution of technology and challenges facing genomics and diagnostic testing to achieve personalized care for individual patients. 11:59 • In addition to time, can you speak on the challenge of access for this type of technology? 13:20 • How have you been able to implement “next day” test results and reports of your technology? 17:50 • Jain and Balmforth on how Biofidelity’s technology can transform the delivery of care, as well as its psychological and mental impact. 19:06 • What’s coming down the line for you and Biofidelity? 20:56 • What are your thoughts for when you expand beyond thoracic oncology? What are your long-term visions for other disease sites? 24:19 • Do you have any thoughts on AI and how it may influence genomics in cancer care? 25:51 • If someone could only listen to the last few minutes of this episode, what would you want them to take away? 28:37 • How to contact Balmforth 30:37 • Thanks for listening 31:10 Barnaby Balmforth, PhD, is co-founder and CEO of Biofidelity. Barnaby has more than 15 years’ experience in the leadership of multidisciplinary technology development. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X, formerly known as Twitter, and LinkedIn: and . Follow Dr. Jain on X, formerly known as Twitter: . Balmforth can be reached via the . Disclosures: Jain reports no relevant financial disclosures. Balmforth reports he is an employee of Biofidelity and owns shares in the company. /episode/index/show/oncologyoverdrive/id/30476478

Uncovering Patient Pearls with Christina Gomez, MD 03/07/2024

Patient and Physician Advocacy with Ashley Sumrall, MD 02/22/2024

Patient and Physician Advocacy with Ashley Sumrall, MD In this episode, host Shikha Jain, MD, speaks with Ashley Sumrall, MD, about advocacy outside of their oncology practices and organizations, what lies ahead for the field of neuro-oncology and more. • Welcome to another exciting episode of Oncology Overdrive :58 • About Sumrall 1:16 • The interview 2:54 • How did you end up in the neuro-oncology space? 3:21 • As a neuro-oncologist, how do you stay up-to-date with neurology, oncology and medicine? 7:28 • Is there a difference in the way you interact with a neuro-oncologist versus a medical oncologist? 8:58 • What drove you to get into the advocacy space? 10:09 • Do you predominantly do advocacy work through ASCO, or do you do it through other avenues as well? 12:20 • If someone is interested in getting involved in becoming an , on the local level or on the national level, what is the best way for them to start that process? 15:24 • How do you talk to people in and outside of organizations about current situations facing health care? 19:40 • If people are interested in learning more about the AMA or getting involved with an organization like the AMA, how can they do so? 22:31 • What do you see coming down the pipeline that you think is going to transform the neuro-oncology space? 27:16 • If someone could only listen to the last minute of this episode, what would you want them to take away? 30:04 • How to contact Sumrall 32:13 • Thanks for listening 32:56 Ashley L. Sumrall, MD, is a neuro-oncologist practicing at Levine Cancer Institute in Charlotte, NC. We’d love to hear from you! Send your comments/questions to Dr. Jain at . Follow Healio on X, formerly known as Twitter, and LinkedIn: and . Follow Dr. Jain on X, formerly known as Twitter: . Sumrall can be reached on X, formerly known as Twitter: . Disclosures: Jain reports no relevant financial disclosures. Sumrall reports receiving funding from Bristol-Myers Squibb, Exelixis, Kura Oncology, Novocure and Oncoceutics, and being a consultant for Abbvie, Athenex, Bayer, Exelixis and Novocure. /episode/index/show/oncologyoverdrive/id/30064398

Oncology Overdrive

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