Psychedelics Today
Psychedelics Today is the planetary leader in psychedelic education, media, and advocacy. Covering up-to-the-minute developments and diving deep into crucial topics bridging the scientific, academic, philosophical, societal, and cultural, Psychedelics Today is leading the discussion in this rapidly evolving ecosystem.
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PT 622 - Matt Xavier - The Psychedelic DJ
08/26/2025
PT 622 - Matt Xavier - The Psychedelic DJ
From the Rave Scene to Psychedelic Therapy In this episode, Kyle Buller speaks with Matt Xavier, DJ, therapist, and author. The conversation took place live at Psychedelic Science. Matt recalls his early years in the rave culture of 1990s New York. He ran record labels, hosted psychedelic trance events, and lived through the intensity of that scene. Why Music Is Medicine Matt believes music should be treated as medicine. He explains how playlists can align with the stages of a psychedelic journey—onset, climb, peak, and descent. He encourages people to listen with intention and to categorize tracks by emotion, energy, and therapeutic impact. Psychedelic Soundtracking Instead of relying only on fixed playlists, Matt performs live mixing during sessions. This method keeps him fully engaged and responsive. He calls the approach “psychedelic soundtracking.” In his view, the guide becomes a tuning fork, adjusting the soundscape to match the client’s process. Key Themes in the Conversation The evolution from rave DJ to therapist and author How music amplifies psychedelics, and why it matters Matching music with each stage of a journey Differences between psilocybin, MDMA, and ketamine work The value of silence, long-form tracks, and harmonic mixing Why buying music supports artists and protects creativity from AI Practical tips for building playlists and rediscovering a love of listening Supporting Artists and Building Community Matt highlights the artists who inspire his work, from ambient pioneers to contemporary sound designers. He urges practitioners to support independent musicians by purchasing their music. In his words, keeping human creativity alive is essential for meaningful psychedelic work. Writing, Mixing, and the Future Matt also discusses his new book and the curated four-hour DJ protocol mix he designed for therapy sessions. He explains how this project grew into a collaborative effort and why writing became a spiritual journey for him. Looking ahead, he hopes to create a training program for others interested in weaving music into psychedelic practice. 🎶 Whether you are a therapist, a DJ, or simply a music lover, this episode shows how sound can transform the psychedelic experience.
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PT 621 - Dr Case Newsom - Zendo Project
08/21/2025
PT 621 - Dr Case Newsom - Zendo Project
In this episode, Joe Moore sits down with Dr. Case Newsom, an emergency room physician in Denver and Medical Director for both Zendo Project and Stadium Medical. They explore how psychedelic harm reduction is merging with event medicine at concerts, festivals, and large-scale gatherings. Dr. Newsom shares his path from osteopathic medical training to bridging emergency medicine with psychedelic peer support. He explains how the Zendo Project has expanded beyond Burning Man, and why collaboration with medical teams matters. The discussion highlights new triage protocols, cultural shifts in Colorado, and the legal challenges that still stand in the way of safer events. Topics Covered The role of the Zendo Project: Peer support, harm reduction, and creating grounded spaces in chaotic environments. Stadium Medical’s model: Covering Denver’s biggest venues and connecting emergency care with psychedelic peer support. Developing medical triage protocols: A simple system that reduces unnecessary ER transports while ensuring sitter and guest safety. Colorado as a hub: Why Denver and Red Rocks are central to psychedelic culture and harm reduction innovation. Legal and regulatory challenges: The impact of the RAVE Act and limits on drug checking services. Research and data collection: Building stronger studies to show venues and first responders the value of harm reduction. Future concerns: Ibogaine’s cardiotoxic risks, the rise of AI-designed drugs, and why medical involvement is urgent. Ketamine in the ER: How ketamine provides pain relief and can create meaningful patient experiences when used with care.
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PT 620 - Kat Murti – Students for Sensible Drug Policy, Meta Censorship, and the Fight for Science
08/18/2025
PT 620 - Kat Murti – Students for Sensible Drug Policy, Meta Censorship, and the Fight for Science
In this episode, Joe Moore is joined by Kat Murti, Executive Director of Students for Sensible Drug Policy (SSDP), the largest youth-led network working to end the war on drugs. SSDP organizes at the campus, local, state, federal, and international levels, with more than 100 chapters across the U.S. and sister organizations worldwide. Kat shares her personal journey into drug policy reform, from witnessing DEA raids on AIDS patients in the 1990s to fighting for civil liberties as a student at UC Berkeley. She explains how SSDP empowers young people to challenge outdated laws and promote policies rooted in compassion, scientific evidence, and human rights. Topics Discussed The War on Drugs as a War on Us: Kat’s early realizations about the drug war’s racism, injustice, and destruction of civil liberties. Her Path to SSDP: From working on California’s Prop 19 cannabis campaign to serving on SSDP’s board and eventually becoming Executive Director. Meta Censorship Campaign: Why Meta’s restrictions on drug education and harm reduction content harm communities, and how SSDP is organizing public pressure to protect freedom of information online. Forced Institutionalization & Executive Orders: Kat critiques recent federal moves to expand forced treatment, cuts to naloxone training programs, and the misguided use of tariffs as “solutions” to the overdose crisis. The Fight Against DEA Scheduling of DOI & DOC: Why these research chemicals are vital to neuroscience and medicine, how SSDP challenged the DEA in court, and what’s at stake for future research. Illogical Drug Policy & Careerism: How prohibition persists due to political incentives, propaganda, and entrenched bureaucratic interests. Building a Better Future: Realigning incentive structures, embracing harm reduction, and supporting community-based solutions to drug use. Key Takeaways The war on drugs is deeply racist, anti-science, and erodes civil liberties. Meta’s censorship of harm reduction information actively endangers lives. Forced treatment doesn’t work—addressing social conditions and providing safe housing does. DOI and DOC, rarely if ever used recreationally, are critical to medical research, and scheduling them would halt decades of progress. Real reform means both ending prohibition and creating environments where people feel supported, connected, and empowered. Links & Resources Students for Sensible Drug Policy (SSDP): Kat Murti on Twitter/X: Kat Murti on Instagram: SSDP Petition against Meta Censorship:
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PT 619 - Sphinx Gate with Mareesa Stertz and Tania Abdul
07/31/2025
PT 619 - Sphinx Gate with Mareesa Stertz and Tania Abdul
In this episode, Joe Moore is joined by Mareesa Stertz and Tania Abdul, the visionaries behind Sphinx Gate, one of Burning Man 2025’s most ambitious and mythic art installations. Inspired by The NeverEnding Story, Sphinx Gate features two towering 34-foot sphinxes and a fully immersive, transformative art experience designed to help participants gain a deeper understanding of themselves. The trio explores how art and play can catalyze personal and collective transformation—without the need for psychedelics—by helping people reframe inner challenges as quests for growth. They discuss the project's mythic inspiration, how it has evolved into a “transmersive” self-discovery journey, and how community co-creation has made this dream real. With rituals, interactive stations, laser-eyed sphinxes, and an oracle offering personalized missions, Sphinx Gate blends storytelling, inner work, and spectacle. They also touch on the deeper intention: shifting culture by normalizing integration, peer support, and emotional exploration—through joy. From honoring Indigenous land stewards to designing future traveling versions and permanent “Museums of Self-Exploration,” this project is just the beginning. Topics Covered: What Sphinx Gate is and how it works The archetypal and cultural roots of sphinxes How The NeverEnding Story inspired the vision Designing integration spaces without psychedelics Co-creation, community magic, and scaling big dreams The emotional and mystical potential of participatory art Fantasia Fridays, Black Rock Philharmonic, and more playa programming Vision for life beyond Burning Man Support Sphinx Gate: Help bring this mythic experience to life and fund its future by donating at Follow: IG:
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PT 618 - Chad Charles - Integrating 5-MeO-DMT: Therapy, Harm Reduction, and Best Practices
07/29/2025
PT 618 - Chad Charles - Integrating 5-MeO-DMT: Therapy, Harm Reduction, and Best Practices
In this episode of Psychedelics Today, Joe Moore sits down with Chad Charles — educator, mentor, and practitioner specializing in 5-MeO-DMT therapy. Chad shares his decade-long journey working with 5-MeO-DMT, emphasizing the importance of: Practitioner training and mentorship Personalized, therapeutic alliances The nuanced understanding of dissociative states Ethics in standardized clinical dosing A trauma-informed approach to psychedelic care He also introduces his upcoming research project, analyzing 500+ one-on-one sessions to illuminate best practices and ethical frameworks in the 5-MeO-DMT space. This is a must-listen for anyone passionate about harm reduction, responsible facilitation, and the future of psychedelic therapy. 🕒 Episode Breakdown 00:00 – Introduction and Guest Welcome 00:41 – Chad Charles' Background and Work 02:18 – Defining 5-MeO-DMT 05:28 – Breathwork and Therapy 09:22 – First Experiences with 5-MeO-DMT 18:00 – Training and Ethical Considerations 30:41 – Conscious Surrender vs. Submission Experience 31:18 – Ethical Considerations in Psychedelic Research 32:02 – Understanding Dissociative Doses 33:26 – Empowering Individuals Through Therapeutic Alliance 34:26 – Challenges in Contemporary Science 38:02 – Good Practice vs. Malpractice in Psychedelic Therapy 41:51 – Personal Experience and Practitioner Responsibility 46:52 – Addressing Malpractice and Corrective Experiences 01:00:11 – Physical Health Considerations in Psychedelic Therapy 01:02:21 – Future Directions and Research in Psychedelic Therapy 01:05:43 – Conclusion and Contact Information
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PT 617 - Alan Davis - Psychedelic Research and Patient Safety at Ohio State & Exploring Ibogaine's Potential
07/24/2025
PT 617 - Alan Davis - Psychedelic Research and Patient Safety at Ohio State & Exploring Ibogaine's Potential
In this episode of Psychedelics Today, Joe Moore sits down with Alan Davis, Associate Professor at Ohio State University, to explore the evolving landscape of Ibogaine research and its therapeutic potential. Alan offers a deep dive into the Iboga Patient Survey, a groundbreaking initiative collecting real-world data on the safety and efficacy of Ibogaine—particularly for those struggling with substance use disorders and mental health challenges. The conversation sheds light on the need for rigorous, community-informed research that could pave the way toward FDA approval and increased access for patients, including veterans dealing with trauma. They also discuss the complexities of clinical trials, the tension between state and federal regulations, and the growing influence of corporate interests in psychedelic research. Alan emphasizes the importance of ethical transparency, community collaboration, and maintaining scientific integrity as the field grows. If you're curious about the intersection of psychedelic medicine, clinical research, and patient safety, this is a must-listen episode. Topics Covered 00:00 – Introduction and Guest Welcome 00:53 – Reflecting on COVID-19's Psychological Impact 01:29 – Introducing the Iboga Patient Survey 01:46 – History and Goals of Ibogaine Research 02:41 – Challenges in Conducting Clinical Trials 03:14 – Importance of Real-World Safety Data 06:55 – Personal Interest in Ibogaine 08:56 – Veterans and Trauma: A Personal Connection 10:53 – Reintegration and Emotional Processing 15:29 – Survey Participation and Accessibility 18:25 – Building Partnerships and Overcoming Challenges 21:06 – Ensuring Safety and Transparency 31:49 – Community and Academic Collaboration 33:06 – Survey Design and Future Research Directions 36:50 – Momentum in Psychedelic Research 37:48 – State vs. Federal Regulation 39:23 – Challenges in Psychedelic Treatment 43:01 – Corporate Interests and Scientific Objectivity 47:20 – Ketamine and Collaborative Research 51:56 – Ibogaine Patient Survey 57:55 – Psychedelics and Pain Research 01:07:22 – Conclusion and Future Directions
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PT 616 - Karina Bashir on Psychedelics, Islam, and Human Rights
07/22/2025
PT 616 - Karina Bashir on Psychedelics, Islam, and Human Rights
In this engaging episode of the Psychedelics Today podcast, host Joe Moore sits down with Karina Bashir, an attorney working at the intersection of law, business ethics, and psychedelics. Karina, of counsel with Antithesis Law and an active member of the psychedelic community, shares her unique journey from human rights advocacy into the evolving field of psychedelic law. The conversation explores her presentation at Harvard on psychedelics and monotheistic religions, and her efforts to bridge the gap between Islamic communities and psychedelic-assisted healing. She discusses the legal frameworks she navigates to support clients in the psychedelic ecosystem, the spiritual depth of Sufism, and the expansive tradition of Islamic philosophy and mysticism. If you’re intrigued by the intersections of religion, law, and psychedelic healing, this episode offers deep insights and hopeful perspectives. 📌 Episode Highlights 00:00 – Introduction and Guest Welcome 00:19 – Meeting at the Psychedelic Safety Institute 01:04 – Karina's Legal Work and Background 04:03 – Human Rights and Migration Work 07:30 – Psychedelics as a Human Rights Issue 18:01 – Legal Challenges in the Psychedelic Space 23:03 – Islam and Psychedelics 28:15 – The Fatwa Process and Islamic Scholars 28:57 – Building Momentum in the Muslim Community 29:08 – Islamic Law and Psychedelics 29:30 – Engaging Muslim Scholars and Community 33:45 – Sufism and Islamic Mysticism 35:09 – Access to Psychedelic Medicine for Muslims 36:49 – Positive Responses and Growing Interest 39:17 – Sufism's Rich Traditions and Practices 40:51 – Intersection of Sufism and Psychedelics 44:14 – Islamic Cosmology and Psychedelic Experiences 51:26 – Concluding Thoughts and Future Directions Attorney, Ethics Advocate, and Program Director at North Star Project Karina Bashir is an accomplished attorney and thought leader working at the intersection of law, ethics, and psychedelics to support a new paradigm of care and equity. She serves as Of Counsel with Antithesis Law, PC, advising clients on corporate formation, risk mitigation, compliance, and ethical best practices. As Program Director at the North Star Project, she advocates for values-driven growth in the psychedelic field through the development of dynamic ethical guidelines. Karina also sits on the Board of Directors of the Psychedelic Bar Association and serves as a steward of its Religious Use Committee. Her work also bridges Islamic thought and psychedelic healing, exploring how spiritual traditions—particularly Sufism—can inform modern approaches to wellness and therapeutic care. She is passionate about increasing access and cultural understanding within Muslim communities engaging with psychedelics. A Fulbright and Gates Cambridge Scholar, Karina holds a JD from UC Berkeley, an MPhil in International Relations from the University of Cambridge, and a BA from the University of Michigan.
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PT 615 - Kristen Nash and Erica Siegel on Risk Reduction and Psychedelic Safety
07/18/2025
PT 615 - Kristen Nash and Erica Siegel on Risk Reduction and Psychedelic Safety
In this deeply important episode of Psychedelics Today, Joe Moore is joined by Kristen Nash, MPH, and returning guest Erica Siegel, LCSW, for a nuanced conversation about risk reduction, harm prevention, and ethical education in the psychedelic space. Kristen shares the powerful and heartbreaking story of losing her 21-year-old son after a tragic psychedelic-related incident. Motivated by this loss and her background in public health, she founded the Coalition for Psychedelic Safety and Education and launched the Before You Trip campaign—an educational initiative piloting in Colorado aimed at helping Gen Z users assess their readiness and safety before engaging with psychedelics. Erica contributes her extensive experience from Nest Harm Reduction and Shine Collective, emphasizing the need for peer-based support, non-abstinence frameworks, and trauma-informed approaches. She highlights common pitfalls such as untrained facilitators, predatory behavior, and the pervasive issue of gaslighting in psychedelic communities. Together, they explore the gaps in current education efforts, the dangers of glorifying substances without context, and the moral injuries that can occur when people are harmed or dismissed by the very communities meant to support them. The conversation calls for broader public funding, lived-experience-informed leadership, and transparency around psychological and relational risks—not just physiological harm. The episode also touches on poly-substance use, the limitations of existing drug harm scales, and the importance of setting, support, and intention. With a shared commitment to saving lives and empowering users, Kristen and Erica offer actionable insights and heartfelt reflections on making this space safer for everyone. Listeners are encouraged to follow and support both Before You Trip and Shine Collective to help expand harm reduction education and survivor advocacy.
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PT 614 - Erica Rex: Scientific Integrity, Psychedelic Research, and the Religious Leader Study
07/15/2025
PT 614 - Erica Rex: Scientific Integrity, Psychedelic Research, and the Religious Leader Study
In this episode, Joe Moore speaks with award-winning science journalist Erica Rex about her personal experience participating in psychedelic research, her upcoming book Seeing What Is There: My Search for Sanity in the Psychedelic Era, and the complex story behind the recently published Religious Leader Psilocybin Study from Johns Hopkins and NYU. They examine: Erica's firsthand experience as a participant in the original 2012 study that helped launch Roland Griffiths’ prominence in psychedelic science. The goals and outcomes of the Religious Leader Study, which sought to explore how psilocybin might impact religious leaders’ effectiveness and connection to their communities. The methodological and ethical problems that plagued the study. The influence of perennialist frameworks and the limitations of measures like the Mystical Experience Questionnaire (MEQ). Broader concerns about the infiltration of religious ideology and lack of rigor in psychedelic science. A deep critique of the institutional systems that allowed flawed research processes to go unchecked — and how these patterns risk repeating the mistakes of the 1960s psychedelic wave. Joe and Erica also dive into how modern psychedelic science struggles to reconcile subjective experience, spirituality, and the reductionist standards of academic research. They discuss Matt Johnson’s paper critiquing “psychedelic consciousness” framing and explore whether our current scientific tools are capable of capturing the depth of psychedelic experience. Erica’s forthcoming book, slated for release in January 2026, blends memoir, neuroscience, and social critique. It offers a critical insider’s view of the psychedelic renaissance—its promise, pitfalls, and the ways it mirrors broader systemic issues in science and culture.
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PT 613 - Daniel Pinchbeck - From Cultural Catalyst to Capitalist Co-optation: Reflections on Psychedelic Science, AI, and Idealist Monism
07/08/2025
PT 613 - Daniel Pinchbeck - From Cultural Catalyst to Capitalist Co-optation: Reflections on Psychedelic Science, AI, and Idealist Monism
In this expansive episode of Psychedelics Today, Joe Moore sits down with author and cultural theorist Daniel Pinchbeck to explore the evolving—and increasingly contested—role of psychedelics in society. From the hopeful spirit of transformation that animated earlier psychedelic movements to the sobering reality of biotech, branding, and political entanglement, Daniel offers a candid diagnosis of where we are—and where we might be headed. Reflecting on Psychedelic Science 2025, Daniel discusses the event’s stark shift toward commercialization and industry influence. He contrasts this with his earlier work on Evolver, a movement that sought to integrate psychedelics with permaculture, alternative economics, and cultural awakening. Together, Joe and Daniel examine how the field’s idealistic origins have been increasingly subjected to capitalist co-option. They also dive into deeper philosophical terrain—discussing monistic idealism, Rudolf Steiner, and the suppression of mystical and paranormal dimensions in the push to medicalize and sanitize psychedelics for mainstream acceptance. Daniel warns of the dangers of ignoring the shadow, including psychic fragmentation and what he calls "entity attachment" from ungrounded use. The conversation ranges from tech billionaires on ketamine to the geopolitical threat of authoritarianism, the weaponization of AI, and the quiet complicity of many in the psychedelic space who avoid political engagement. Daniel shares his current projects, including his Substack newsletter and a new seminar, Breaking the AI Barrier. This is a timely, unflinching exploration of psychedelics as both medicine and mirror—revealing the best and worst of our collective intentions. Can we reclaim the visionary potential of these tools from the grip of capital and control?
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PT 612 - Mattha Busby: Power, Pleasure, and the Psychedelic Movement’s Reckoning
07/03/2025
PT 612 - Mattha Busby: Power, Pleasure, and the Psychedelic Movement’s Reckoning
In this wide-ranging conversation, journalist Mattha Busby joins Joe Moore to reflect on the shifting tone of the psychedelic movement in the wake of Psychedelic Science 2025. Based in Vancouver, Mattha has written for The Guardian, VICE, Esquire, TIME, and Wired, bringing a uniquely embedded yet critical lens to the space. They discuss the post-conference mood and the sense that the industry is sobering up—less hype, more introspection. Mattha reflects on the growing division between underground practitioners, activists, and biotech startups, and the importance of vision, ethics, and scrutiny in the midst of this cultural moment. Other topics include: Ketamine overuse and dependence, especially in social and parenting contexts The future of psychedelic nightlife, harm reduction, and mocktail bars Gender and sexual fluidity as uncovered through psychedelics Questions of IP, underground wisdom, and psychedelic ownership Psychedelics as tools for peacebuilding, especially in conflict zones The shadow side of spiritual experiences and how to spot bad actors The value of pleasure, intimacy, and human connection in the psychedelic journey Joe and Mattha also reflect on the resurgence of psychedelic use in Texas, the legacy of the Stark Club, and how Christian libertarianism and military trauma might influence unexpected policy changes. This conversation is bold, honest, funny, and thoughtful—exactly the kind of cultural critique the movement needs right now. Find and on . His new pocketbook on drug policy is available now.
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PT 611 - Dylan Beynon - Mindbloom
07/01/2025
PT 611 - Dylan Beynon - Mindbloom
Dylan Beynon: At-Home Ketamine Therapy, Big Pharma Pushback, and the Future of Psychedelic Accessibility In this episode, Joe Moore welcomes Dylan Beynon, CEO and Founder of , one of the largest providers of legal, at-home ketamine therapy in the U.S. Dylan shares the deeply personal story that led him to psychedelic medicine—including the tragic loss of his mother and sister to addiction and mental illness—and how these experiences continue to fuel his mission to make psychedelic therapy affordable and accessible for all. Mindbloom has now facilitated over 654,000 sessions across 38 states, offering both sublingual and subcutaneous (injectable) ketamine in a comprehensive treatment program that includes preparation, integration, music, journaling, and even generative AI art. The conversation dives into common criticisms of at-home ketamine, the benefits of guided treatment over IV infusions, and the disturbing influence of Big Pharma in media narratives—especially the growing PR push behind SPRAVATO. Dylan also breaks down what makes Mindbloom’s outcomes stand out, why they recently added injectable ketamine, and how their safety data challenges popular misconceptions. Joe and Dylan also touch on the potential future of at-home MDMA therapy, regulatory hurdles, and what it will take to scale these powerful treatments to millions of people in need. If you're in the psychedelic field, considering ketamine therapy, or curious about the ethics and economics of psychedelic medicine, this episode offers a powerful look behind the curtain. Resources:
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PT 610 - Victoria Litman - The Future of Psychedelic Regulation Is Local
06/27/2025
PT 610 - Victoria Litman - The Future of Psychedelic Regulation Is Local
In this episode, we sit down with ., to discuss why the future of psychedelic access in the United States is being shaped not by federal agencies, but by the bold actions of individual states. As a legal scholar and writer focusing on drug policy, Victoria breaks down the significance of the FDA’s 2024 rejection of psychedelic-assisted therapy, and why that decision might be less of a setback than it seems. We explore how state-level initiatives like Oregon’s Psilocybin Services Act and Colorado’s Natural Medicine Health Act are setting the stage for a new model of access—one rooted in harm reduction, personal liberty, and existing regulatory infrastructure. Victoria discusses the importance of the Tenth Amendment and the Anti-Commandeering Doctrine, which allow states to move forward regardless of federal inaction. Rather than waiting for slow-moving federal institutions, Victoria argues that states can build safe, scalable systems now—especially by leveraging cannabis infrastructure for psychedelic regulation. She also touches on the ethical and cultural implications of this transition, including protections for spiritual and religious use. If you’re wondering what psychedelic policy will look like in the years ahead, this episode offers an insightful and hopeful roadmap.
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PT 609 - PS 25 Morning Show - Day Three
06/20/2025
PT 609 - PS 25 Morning Show - Day Three
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PT 608 - PS 25 Morning Show - Day Two
06/20/2025
PT 608 - PS 25 Morning Show - Day Two
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PS 25 - Morning Show Number 1
06/19/2025
PS 25 - Morning Show Number 1
Joe Moore and Anne Philippi are hosts of the PS25 Morning Show! This one features Dee Dee Goldpaugh, LCSW and Tommaso Barba, PhDC! We talk about all things Sex and Psychedelics!
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PT 606 - Ibogaine and the Future of Healing: Trevor Millar & Jonathan Dickinson of Ambio Life Sciences
06/16/2025
PT 606 - Ibogaine and the Future of Healing: Trevor Millar & Jonathan Dickinson of Ambio Life Sciences
n this episode of Psychedelics Today, kicking of Psychedelic Science 2025 week in Denver, we sit down with Jonathan Dicksinson, Chief Executive Officer, and Trevor Millar, Chief Operations Officer of Ambio Life Sciences – one of the world’s leading ibogaine clinics – to explore the potential of ibogaine for addiction, neuroregeneration, and how ethics, honoring experience, and sustainability will be key to delivering ibogaine at scale. Trevor shares his early work supporting marginalized populations in Vancouver’s Downtown Eastside, which led to the founding of Liberty Root, one of Canada’s first ibogaine clinics. Jonathan reflects on his apprenticeship in Mexican clinics, years of international advocacy with the Global Ibogaine Therapy Alliance, and drafting the first set of clinical guidelines for ibogaine detoxification. Together with paramedic and ibogaine safety protocols expert Jose Inzunza, they co-founded Ambio in Tijuana in 2021. They discuss: The unique safety standards Ambio has pioneered – including industry-wide clinical protocols and magnesium therapy to mitigate cardiac risk. Their scale: over 3,000 patients treated, with 100+ clients per month across five dedicated houses in Baja California. Ambio’s groundbreaking neuroregenerative program for Parkinson’s, MS, and traumatic brain injury – which has already drawn patients like Brett Favre and Clay Walker. How ibogaine appears to drive profound physiological change – including evidence of TBI reversal as shown in Stanford’s 2024 study on Special Forces veterans. Why ibogaine isn’t just a molecule – it opens a long-lasting “critical period” of neuroplasticity that must be supported with preparation, integration, and holistic care. The deeper story of sourcing: through his company Terragnosis, Jonathan is the only person with a legal export license for Tabernanthe iboga from Gabon, and Ambio is setting a precedent for reciprocal and ethical global supply chains. Their cautionary perspective on Texas’ $50M push toward ibogaine clinical trials – and why the traditional “one drug, one indication” model misses the complexity and promise of psychedelic healing. They also make a compelling case that Ambio is already modeling what the future of psychedelic care should look like – not a single drug in a sterile clinical setting, but a comprehensive, integrated protocol combining preparation, medical oversight, and deep integration. “Start with the end in mind,” Trevor urges – Ambio isn’t just part of the movement; it’s the blueprint for how ibogaine could be delivered worldwide. Links: Ambio Website: (Frontiers in Immunology, Feb 2025) (Nature Medicine, Jan 2024) (Frontiers in Pain Research, Aug 2023) (Journal of Psychedelic Studies, Jan 2020) Bios: Jonathan Dickinson is the Chief Executive Officer and Co-Founder of Ambio Life Sciences. One of the world’s leading experts on ibogaine, Jonathan brings over 15 years of experience in clinical care, traditional practice, and psychedelic research to his leadership at Ambio. A Mexico-licensed psychologist and former Executive Director of the Global Ibogaine Therapy Alliance, he authored the field’s foundational safety guidelines and has published widely on ibogaine’s therapeutic, cultural, and ecological significance. He holds the only active export license for Tabernanthe iboga root, led the first Nagoya-compliant export from Gabon, and was initiated into the Dissoumba/Fang tradition of Bwiti in 2014 and the Missoko tradition in 2022. He has co-authored peer-reviewed research on ibogaine’s potential for trauma, TBI, pain, MS, and Parkinson’s. At Ambio, he leads strategy, research, and innovation – advancing a globally scalable model of care that bridges tradition, science, and integrity. Trevor Millar is the Chief Operating Officer and Co-Founder of Ambio Life Sciences. A social entrepreneur and pioneer in ibogaine advocacy and treatment, Trevor brings over a decade of experience supporting individuals through addiction recovery, trauma healing, and post-treatment integration. His background includes co-founding the Canadian Psychedelic Association and serving as Chair of the Board for MAPS Canada. He has co-authored peer-reviewed research on ibogaine’s applications for trauma, TBI, and opioid use disorder, and has been featured in award-winning documentaries including DOSED and In Waves and War. Grounded in personal experience and guided by a philosophical approach to healing, Trevor is helping shape a new model for ethical, integrative psychedelic care on a global scale. At Ambio, Trevor leads operations, strategic partnerships, and client experience – bridging clinical care with systems design, education, and public advocacy.
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PT 605 - Jeff Breau - Exploring Psychedelic Churches at Harvard Divinity School
05/27/2025
PT 605 - Jeff Breau - Exploring Psychedelic Churches at Harvard Divinity School
In this episode of Psychedelics Today, hosts sit down with Jeff Breau from Harvard Divinity School's Center for the Study of World Religions. Key themes include the intersection of psychedelics and religion, harm reduction practices, and the burgeoning psychedelic church movement. Jeff brings insights from his ethnographic research on psychedelic churches and discusses the importance of interdisciplinary collaboration for advancing understanding in this field. He also delves into the role of music in psychedelic therapy, critiques of the Mystical Experience Questionnaire (MEQ), and the potential for psychedelic chaplaincy. Tune in for an enlightening conversation on the evolving landscape of psychedelics in society and spirituality. 00:00 Introduction and Welcome 00:18 Music in Psychedelic Therapy 02:13 Cultural Context of Music in Therapy 06:08 Personal Journey into Psychedelics and Religion 08:40 Living at an Ashram and Spiritual Practices 15:52 Mystical Experience Questionnaire (MEQ) 33:01 Psychedelic Churches and Legal Challenges 46:11 The Intersection of Law and Religion 46:34 Emergence of Psychedelic Churches 48:41 The Democratization of Mystical Experiences 49:49 Technologies of Revelation 51:10 Novel Rituals and Spiritual Practices 53:49 Humor and Irreverence in Religion 56:44 Reevaluating the Term 'Cult' 01:10:11 Psychedelic Chaplaincy and Spiritual Care 01:18:44 Burning Man as a Model for Religiosity 01:22:43 The Rise of Iboga in American Christianity 01:25:56 Conclusion and Future Directions Links
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PT 604 - Paul Gillis-Smith - Psychedelics, Religion & Lisa Bieberman
05/21/2025
PT 604 - Paul Gillis-Smith - Psychedelics, Religion & Lisa Bieberman
In this episode, Joe Moore sits down with from to discuss a range of fascinating topics. They begin by discussing the Harvard Divinity School and the CSWR’s mission and history. The conversation delves into the work and legacy of , a pivotal figure in the 1960s psychedelic harm reduction movement. It explores her contributions to the field through her Psychedelic Information Center. They also touch on the Quaker traditions and their intersection with LSD use, showing how spirituality and psychedelics can coalesce. Paul also talks about upcoming psychedelic and chaplaincy workshops, emphasizing the importance of spiritual care in psychedelic experiences. This episode is rich with historical insights and contemporary applications, making it a must-listen for anyone interested in psychedelics and spirituality. 00:00 Introduction and Initial Setup 00:34 Meeting at Penn's Psychedelic Conference 01:14 Postdoctoral Presentations and Indigenous Plant Medicine 03:27 Understanding CSWR and Its Evolution 07:21 Harvard's Study of Psychedelics in Society and Culture 09:11 Personal Academic Journey and Interest in Psychedelics 11:58 Role at CSWR and Ongoing Projects 18:59 Lisa Bieberman: A Pioneer in Psychedelic Education 40:53 Quaker Theology of LSD 41:58 Meeting Structure and Frequency 42:46 Profound Simple Truths 45:41 Transition to Quakerism 48:45 The New Jerusalem Prophecy 53:02 Quakerism and Its Influence 01:11:25 Clinical Chaplaincy and Psychedelics 01:18:39 Conclusion and Future Projects
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PT 603 - Dr Simon Ruffell - Other Ways of Knowing
05/13/2025
PT 603 - Dr Simon Ruffell - Other Ways of Knowing
In this episode of Psychedelics Today, Joe Moore speaks with Dr. Simon Ruffell, a London-based psychiatrist, researcher, and curandero-in-training in the López Mahua lineage of the Shipibo tradition. Dr. Ruffell shares how his early fascination with psychiatry eventually led to a deep disillusionment with the limitations of conventional treatments—and a surprising pivot toward the Amazon. Now working at the intersection of Indigenous healing and clinical research, Ruffell describes his journey from medical school to shamanic apprenticeship. He offers insight into the Shipibo understanding of illness across three planes—spiritual, psychological, and physical—and how these ideas challenge Western frameworks. The conversation explores critical questions about the psychedelic renaissance: Are current clinical models missing the energetic and spiritual dimensions of healing? What are the risks of poorly held psychedelic sessions, and how can Indigenous knowledge guide safer practices? Dr. Ruffell advocates for deep training, cross-cultural respect, and collaborative models—such as pairing Indigenous healers with psychiatrists in clinical settings. He also discusses his work with and , organizations that partner with Indigenous communities to study the effects of ayahuasca, particularly in treating PTSD among military veterans. Early findings from their five-year study show that 84% of participants no longer meet PTSD criteria six months after retreat—a promising signal for integrative approaches. This episode offers a rare look at how science and spirituality can coexist. Whether you're a clinician, researcher, or someone seeking deeper healing, Dr. Ruffell’s story invites us to question our assumptions and expand our understanding of what true medicine can be.
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PT 602 - Iboga - Talia Eisenberg, Tom Feal, Dr. Lola “Dr. O” Hoba, Kevin Franciotti
05/06/2025
PT 602 - Iboga - Talia Eisenberg, Tom Feal, Dr. Lola “Dr. O” Hoba, Kevin Franciotti
Aspen Psychedelic Symposium 2024 – Hosted by Kevin Franciotti This powerful panel explores the healing potential and complex responsibilities that come with working with Ibogaine, a potent plant-based psychedelic. Moderator Kevin Franciotti guides a heartfelt and informative conversation with Talia Eisenberg, Tom Feegel, and Dr. Lola "Dr. O" Hoba, highlighting personal transformation, medical protocols, and the importance of honoring traditional knowledge. Personal Journeys with Ibogaine Talia Eisenberg shares her recovery from opioid addiction and the founding of BEOND Ibogaine, a medical treatment center in Cancun, Mexico. Her story illustrates the plant’s unique power to interrupt addiction and awaken purpose. Tom Feegel, co-founder and CEO of BEOND, shares how his own trauma and long-term sobriety inspired a vision for a safe, respectful, and medically supervised environment for deep healing. Clinical and Cultural Wisdom Dr. Lola Hoba offers insights as a pharmacist and Yoruba herbalist, bridging traditional plant medicine knowledge with modern pharmacology. She describes how iboga works on multiple brain receptors and why it holds so much promise for treating addiction, depression, and trauma. She also cautions about its cardiac risks and calls for respectful, trained facilitation. Safety, Access, and Sustainability Panelists discuss the rigorous safety protocols at BEOND, including ICU-level care, psychiatric screening, and pre-treatment evaluations. They also explore broader questions: How can this medicine be offered responsibly? What does reciprocity mean in practice? BEOND supports Blessings of the Forest, a nonprofit in Gabon that works to stop poaching and protect Indigenous access to the sacred root. A Call for Balance and Respect This conversation highlights the importance of blending science, spirit, and social justice. From trauma healing to sustainable sourcing, each panelist emphasizes the need for compassion, caution, and connection. As laws change and access grows, the panel urges all involved to move forward with care—for the medicine, the people it serves, and the cultures that have stewarded it for generations.
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PT 601 - Neuropharmacology: Psychedelics on the Brain - Jim Harris, Rachel Zoeller, DPT, David W. Mcmillan, Ph.D., and Manesh Girn, Ph.D.
05/02/2025
PT 601 - Neuropharmacology: Psychedelics on the Brain - Jim Harris, Rachel Zoeller, DPT, David W. Mcmillan, Ph.D., and Manesh Girn, Ph.D.
A panel discussion with Jim Harris, Rachel Zoeller, DPT, David W. McMillan, Ph.D., and Manesh Girn, Ph.D. Recorded live at the Aspen Psychedelic Symposium In this riveting and deeply personal conversation, moderator Jim Harris is joined by three pioneers at the intersection of neuroscience, psychedelics, and disability: Dr. Rachel Zoeller (Doctor of Physical Therapy and spinal cord injury survivor), Dr. David McMillan (Assistant Professor of Neurological Surgery at the University of Miami), and Dr. Manesh Girn (neuroscientist and postdoctoral researcher with Robin Carhart-Harris at UCSF). Together, they explore how psychedelics may do far more than treat depression or catalyze mystical experiences—they may also support healing and regeneration in the nervous system. The discussion opens with an acknowledgment that our cultural understanding of psychedelics has mostly focused on their psychological and spiritual effects. But as these experts reveal, the somatic potential of psychedelics is vast and understudied. They delve into promising areas like central and peripheral neuroplasticity, the anti-inflammatory effects of psychedelics, and how these mechanisms might play a role in healing from spinal cord injuries or paralysis. Dr. Girn breaks down the science behind psilocybin's interaction with 5-HT2A serotonin receptors, not only in the brain but also in the spinal cord. These receptors, when activated, may increase neuronal excitability and even help restore lost signaling in damaged motor pathways. He suggests that psychedelics could reopen “critical periods” for neuroplasticity—windows of opportunity for the nervous system to rewire and heal. Rachel Zoeller shares her powerful lived experience as both a physical therapist and a spinal cord injury patient. Her story brings the science to life, particularly her observation that psychedelic experiences help her reconnect to parts of her body affected by paralysis. Psychedelics, she suggests, have allowed her to rebuild mind-body communication and foster compassion toward her own physical limitations. She also underscores the need for patients to cultivate body awareness, meditation, and breathwork as essential tools for safe and effective psychedelic use. Dr. McMillan, who leads outreach at the Miami Project to Cure Paralysis, provides a clinical and safety-oriented perspective. While optimistic about the potential, he urges caution—especially with individuals who have high-level spinal cord injuries and are vulnerable to serious complications like autonomic dysreflexia. He stresses that before we can bring these treatments into clinical settings, we must carefully assess physiological risk, develop precise pharmacological protocols, and prioritize patient safety. The panel also addresses cultural and spiritual interpretations of spasticity. Drawing on both shamanic and somatic perspectives, they propose that these involuntary muscle contractions could be reinterpreted not as dysfunction, but as potential portals for healing, integration, or neurological feedback. The idea that such spasms might help the brain remap muscle groups is discussed as a provocative and hopeful reframe. The conversation wraps with a call to action: to bring together indigenous wisdom, embodied knowledge, rigorous science, and community storytelling in order to chart a new frontier in psychedelic medicine—one that does not leave the disabled community behind. As McMillan puts it, "There’s a lesson to psychedelia from paralysis.” It’s a reminder that neuropharmacology must consider not just molecules and mechanisms, but people and possibilities. Whether you're a clinician, researcher, patient, or curious explorer, this panel is a moving and illuminating look at how psychedelics could transform not only minds—but bodies. Thanks to Aspen Public Radio, Aspen Psychedelic Resource Center, Healing Advocacy Fund and Aspen Psychedelic Symposium for allowing us to share this podcast. A full agenda from the symposium can be found .
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PT 600 - Sandor Iron Rope and Zach Leary
04/29/2025
PT 600 - Sandor Iron Rope and Zach Leary
In this special panel, Joe Moore of Psychedelics Today is joined by Sandor Iron Rope, Lakota spiritual leader and peyote practitioner, and Zach Leary, writer and advocate for psychedelic culture. Together, they explore the critical importance of respecting the cultural, spiritual, and ecological roots of plant medicines. Sandor shares powerful reflections on the Lakota worldview, the trauma of colonization, and the deep spiritual kinship indigenous peoples hold with medicinal plants. Zach reflects on the American counterculture's relationship with psychedelics, highlighting the need to preserve mysticism and community over commercialization. The panel dives into challenges around synthetic versus natural medicines, the risks of spiritual harm when practices are rushed or disconnected from tradition, and the urgent need for indigenous voices at the table as psychedelic policy evolves. Throughout, a theme emerges: slow down, honor kinship, and build right relationship with nature, culture, and spirit. This conversation offers a rare and necessary bridge between indigenous wisdom and the psychedelic resurgence, calling for respect, collaboration, and a return to deep roots to guide future generations. Learn more at and .
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PT 599 - Sarko Diane and Rick - First to Respond
04/25/2025
PT 599 - Sarko Diane and Rick - First to Respond
This podcast comes from the Aspen Psychedelic Symposium from last summer. It features Diane Goldstein who is the executive director of Law Enforcement Action Partnership, Sarko Gergerian a police officer from Winthrop, Mass and Rick Doblin from MAPS. This panel was introduced by Zach Leary and was a highlight of our trip to Aspen's conference last year. We discuss new ways in which police should or could consider psychedelics and drugs more generally. Thanks to Aspen Public Radio and Aspen Psychedelic Symposium for allowing us to share this podcast.
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PT 598 - Zach Leary - Your Extraordinary Mind
04/20/2025
PT 598 - Zach Leary - Your Extraordinary Mind
In this episode Kyle Buller and Joe Moore speak to Zach Leary about his new book "". Kyle and Joe join Zach in person for this recording. Zach has lots of hard earned wisdom and gracefully shares it with us and with his readers. We discuss MAPS PS25, Psychedelic Churches, psychedelic overuse and much more. Join us to learn more.
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PT 597 - LP Giobbi – Dead House, Psychedelic Creativity, and Fem House Empowerment
04/17/2025
PT 597 - LP Giobbi – Dead House, Psychedelic Creativity, and Fem House Empowerment
In this episode, Joe Moore welcomes LP Giobbi, an internationally famous DJ, electronic music producer, and jazz pianist. LP shares the story behind Dead House, her project blending Grateful Dead samples with house music. What started as a tribute to her parents during pandemic live streams has become a celebrated musical movement. Joe and LP explore the deeper connection between music and psychedelics. They talk about Bicycle Day, the story of Albert Hofmann’s famous LSD bike ride, and how psychedelics can support creativity and personal growth. LP opens up about her own experiences with psychedelics, touring burnout, and how she’s learning to reconnect with her body through music and intention. The conversation also highlights LP’s work with Fem House, an educational platform that empowers women and gender-expansive individuals in music production. She explains how representation, access, and support are key to shifting the music industry. This is a warm, inspiring, candid episode about breaking barriers, finding your voice, and leading purposefully.
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PT 596 - Kayse Gehret - The Modern Guide: Microdosing, Facilitation & Community
04/15/2025
PT 596 - Kayse Gehret - The Modern Guide: Microdosing, Facilitation & Community
In this episode, Kyle Buller speaks with Kayse Geheret, founder of Microdosing for Healing and instructor for Psychedelics Today’s Vital program. They explore what it means to be a modern guide in the world of psychedelics. Kayse shares how microdosing has become a key entry point for many and highlights the importance of training, community, and personal growth. They discuss how not all psychedelic work involves facilitation. Some guides support through integration, education, or community organizing. The conversation covers what makes a great guide—qualities like groundedness, empathy, curiosity, and the ability to hold space. They also talk about the growing need for psychedelic-literate professionals in all fields, not just therapy. Kayse and Kyle reflect on the importance of finding the right training—whether for coaching, integration, or peer support. With more people entering the space, education and connection are more important than ever. Whether you’re curious about microdosing, thinking of becoming a guide, or simply want to better support your community, this episode offers valuable insight. 🎧 Learn more at 🌱 Discover Vital at
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PT 595 - Harry Pack - Psychedelic Surrealism
04/11/2025
PT 595 - Harry Pack - Psychedelic Surrealism
Joe Moore sits down with UK-based artist Harry Pack, whose vibrant, surreal, and often psychedelic art has captured the attention of dreamers, psychonauts, and seekers worldwide. Known for channeling the aesthetic of altered states rather than simply replicating them, Harry discusses his journey from childhood doodles to being a full-time artist working digitally in Procreate. He shares stories of deep inspiration from figures like Ott—whose album Hiraeth he recently illustrated—and how art has helped him integrate mystical experiences, recovery, and even potential alien contact. The conversation explores the therapeutic potential of art, the role of storytelling in visionary creativity, and the emergence of recurring themes in Harry’s work—most notably, the enigmatic “Purple UFO.” We also get into the importance of community, nature, and play in feeding the creative spirit, and Harry’s aspirations to build spaces for collective art-making and integration. Follow Harry on Instagram and , and explore his work at .
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PT 594 - Jean-Francois Sobiecki - African Psychoactive Plants & Phytoalchemy
04/08/2025
PT 594 - Jean-Francois Sobiecki - African Psychoactive Plants & Phytoalchemy
In this episode of Psychedelics Today, Joe Moore sits down with South African ethnobotanist and healer Jean-François Sobiecki to explore the rich and largely underrecognized world of African psychoactive plants. With over two decades of fieldwork and research, Jean-François sheds light on the traditional use of these plants in healing, divination, and spiritual practices across Southern Africa. Topics covered include: Jean-François’s early inspirations and the ancestral roots of his herbal knowledge His discovery and documentation of 306 African psychoactive plant species The ritual use of Ubuwalu (dream-enhancing emetic infusions) and their role in personal transformation How vomiting, dietary restrictions, and sensory isolation are used as part of initiation processes Cross-cultural parallels between Southern African and Amazonian plant healing traditions The underexplored use of psychoactive plants to treat mental health conditions like schizophrenia and hysteria Ethical fieldwork, indigenous knowledge protection, and the dangers of overharvesting sacred plants Visions for healing and conservation gardens in Africa and the role these plants could play in global mental health Jean-François shares moving stories of his 15-year mentorship with a Northern Sotho diviner and healer, Letti Ponnya, and how she introduced him to African “plant teacher” medicines. His message is clear: Africa has a deep, sophisticated, and scientifically underappreciated tradition of psychoactive plant use that deserves recognition, respect, and further study. 📘 Get the book: 🌐 Learn more at: 📝 Related reading: ➡️
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PT 593 - Vince Kadlubek - Meow Wolf & PORTAL
04/04/2025
PT 593 - Vince Kadlubek - Meow Wolf & PORTAL
In this inspiring and far-reaching conversation, Joe Moore is joined by Vince Kadlubek, the founder and Chief Visionary Officer of , the groundbreaking arts and entertainment company known for its massive, immersive art experiences. Together, they dive deep into humble DIY origins, its evolution into a multi-city creative juggernaut, and how it intertwines with psychedelic culture and expanded states of consciousness. Vince shares the story of formation in Santa Fe, the evolution from a group of passionate friends into a thousand-person company, and the power of belief, creativity, and visionary leadership. He reflects on raising funding from and major investors, navigating massive growth, and the challenge of keeping the creative spark alive in the face of institutionalization. They also discuss the upcoming , which will feature performances, talks, and immersive experiences throughout the exhibition—with appearances from Reggie Watts, Duncan Trussell, Zach Leary, and more. From the imaginative to the esoteric, Vince and Joe explore the intersection of psychedelics and art, the nature of reality and the imaginal realm, and how to build beauty and wonder into the world around us. 🌀 Topics Covered What Meow Wolf is and how it all began Growing from a DIY collective to a nationwide phenomenon Maintaining creative spirit through growth and structure Vision, belief, and the spiritual work of creating art Navigating private equity and big funding in the arts Santa Fe’s unique cultural and energetic imprint Fictional character sentience and AI in immersive worlds Art as a cultural response in times of uncertainty Psychedelics as tools for accessing the imaginal and creative realms Hosted by Portal, this one-of-a-kind immersive celebration of Bicycle Day takes over the entire Meow Wolf Denver space. Expect DJs, speakers, psychedelic storytelling, ecstatic dance, art, and surprises around every corner. Featured Guests Include: Reggie Watts Duncan Trussell LP GIOBI (Dead House) Zach Leary David Satori (Dirtwire) Frick Frack Blackjack Dennis Walker Veronica Lightning Horse Perez …and many more to be announced! 🌀 Plus: . 📍 More Info Learn more about Check out for Bicycle Day details 📣 Support the Show If you love what we do, please share this episode, leave a review, and consider supporting us in our Navigators Program.
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