RealTalk MS
Jon Strum cuts through all the jargon and breaks down the latest multiple sclerosis news. You’ll meet the scientists who are creating tomorrow’s MS treatments today. You’ll hear from the experts discussing how the latest tweaks and changes to our healthcare laws will impact your MS treatment. And we’ll be talking to the courageous MS warriors who are out there advocating on behalf of the MS community every day, as well as the men and women who are committed to living their best lives with MS and living their best lives as MS caregivers. If you're dealing with multiple sclerosis in your life -- as a patient, caregiver, family member, or friend -- join us each week for RealTalk MS.
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Episode 437: Remembering David Mitchell
01/12/2026
Episode 437: Remembering David Mitchell
I don't have to remind anyone who listens to this podcast that the cost of MS disease-modifying therapies is obscenely high. And we're not just talking about relatively new medications. Older medications -- some decades old -- continue to increase in price without any rational explanation for why or how. On January 2nd, we lost a true warrior in the ongoing battle to lower the price of prescription drugs when David Mitchell, the founder of Patients for Affordable Drugs, passed away. I met David in 2018 at a National MS Society Public Policy Conference, and he was a guest on Episode 31 of RealTalk MS. This week, I'm re-sharing the conversation we had in 2018. We'll also tell you about an international workshop that represents the initial steps in developing a global research agenda to end MS. We're explaining how AI is about to have a major impact on healthcare. And we'll share the American Medical Association's brief to Congress, making the case for extending access to telehealth. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: We're remembering David Mitchell :22 The first steps toward a global research agenda to prevent MS were just published 1:02 Doctor AI will see you now 5:45 The American Medical Association asks lawmakers to extend access to telehealth 10:27 David Mitchell in his own words 12:41 Share this episode 27:56 Next week 28:16 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at Patients for Affordable Drugs PAPER: Toward a Global Research Agenda for Preventing Multiple Sclerosis AMA BRIEF: The Case for Permanent Telehealth Policy and Expanded Access to Virtual Care ChatGPT Health JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 437 Guests: David Mitchell
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Episode 436: 3 Questions Your Neurologist Should Be Asking Themselves with Dr. Leorah Freeman
01/05/2026
Episode 436: 3 Questions Your Neurologist Should Be Asking Themselves with Dr. Leorah Freeman
Scientists are expanding our understanding of MS at an unprecedented pace. This week, Dr. Leorah Freeman discusses why, as new discoveries and medications enter clinical practice, neurologists and MS specialists should ask themselves 3 important questions when considering a patient's treatment plan. Dr. Freeman is the Director of the Multiple Sclerosis and Neuroimmunology Center at Dell Medical School at the University of Texas at Austin, where she also leads the MS and Neuroimmunology fellowship program and the MS Imaging and Outcomes Research Laboratory. We'll also tell you about study results that reveal two distinct biologically-informed MS subtypes. We're explaining some of the confusing background to the FDA's decision not to approve a disease-modifying therapy that achieved positive results in its Phase 3 clinical trial. And did we really need a study to tell us that people living with MS fear experiencing a relapse or disease progression? Well, yes. We'll explain why. We're also reminding you to mail your insurance premium payments and other important documents earlier than you have in the past. And we're sharing details about the two clinical trials that received $4.1 million in funding as part of the International Progressive MS Alliance Experimental Medicine Trial Awards. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: 3 questions your neurologist should be asking themselves :22 Public Service Announcement: How the new rule about postmarks could affect your healthcare 1:16 FDA says it's not ready to approve Tolebrutinib 3:16 Study identifies two biologically-informed MS subtypes 6:29 Study results remind us that people with MS fear relapse and progression 10:09 The International Progressive MS Alliance invests $4.1 million in two clinical trials 14:04 Dr. Leorah Freeman discusses why neurologists need to ask themselves 3 important questions when considering a patient's treatment plan 17:18 Share this episode 33:16 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at The Multiple Sclerosis Insider STUDY: Combined Magnetic Resonance Imaging and Serum Analysis Reveals Distinct Multiple Sclerosis Types STUDY: Fear of Disease Progression and Relapse in Multiple Sclerosis: A Systematic Scoping Review JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 436 Guests: Dr. Leorah Freeman
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Episode 435: Revisiting ECTRIMS 2025 with Dr. Bruce Bebo and Kristine Werner Ozug
12/29/2025
Episode 435: Revisiting ECTRIMS 2025 with Dr. Bruce Bebo and Kristine Werner Ozug
We're closing out the year by revisiting the most listened-to episode of RealTalk MS in 2025. And it shouldn't come as a major surprise that this year's most listened-to episode was our review of the largest MS research conference in the world, ECTRIMS. This episode features the annual conversation that I have with Dr. Bruce Bebo, right outside of the conference center, just minutes after ECTRIMS adjourns. Dr. Bebo is the Executive Vice President of Research at the National MS Society, and each year, he very generously closes out 3 days of nonstop meetings, presentations, and research reviews by sharing his initial thoughts on the announcements and presentations that caught his eye during the conference. When I produced this episode last September, I also wanted to capture a patient's perspective on what can easily become an overwhelming 3 days of presentations, news, and announcements. Kristine Werner Ozug, a member of the RealTalk MS team who lives with MS, joined me right after the conference to share her perspective on ECTRIMS 2025. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: ECTRIMS 2025 :22 Dr. Bruce Bebo shares his first impressions of the news and research presented at ECTRIMS 2025 1:22 Kristine Werner Ozug weighs in with an MS patient's perspective on the news and research presented at ECTRIMS 2025 10:35 Share this episode 22:45 Next week on RealTalk MS 23:06 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at RealTalk MS at ECTRIMS 2025 on YouTube Join the RealTalk MS Facebook Group Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 435 Guests: Dr. Bruce Bebo and Kristine Werner Ozug
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Episode 434: Revisiting Managing Menopause While You're Managing MS with Dr. Riley Bove
12/22/2025
Episode 434: Revisiting Managing Menopause While You're Managing MS with Dr. Riley Bove
The holiday season gives me the opportunity to indulge in what's become a RealTalk MS tradition. I reserve the last two episodes in December to revisit the most popular conversations that I've had over the past year. Women represent two-thirds of the MS population. Yet, surprisingly, there isn't nearly enough data related to women's health issues and MS. With an estimated 300,000 women living with MS in the United States who are currently in peri- or post-menopause, researchers have started to focus on how menopause and MS interact, and the best ways to treat symptoms of each. This brings me to a conversation I had last March about managing menopause while managing MS with Dr. Riley Bove. Dr. Bove is a neurologist and the founding director of the Sex and Gender-Enriched (SAGE) Neurology Program at the University of California, San Francisco, and she's considered one of the world's foremost experts on women's health issues and MS. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Managing menopause while you're managing MS :22 Dr. Riley Bove discusses some of the issues facing the estimated 30% of the MS population who are currently in peri- or post-menopause 1:53 Share this episode 20:30 Next week on RealTalk MS 20:51 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at RealTalk MS at ECTRIMS 2025 on YouTube Join the RealTalk MS Facebook Group Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 434 Guests: Dr. Riley Bove
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Episode 433: Our Most Important Conversations of 2025 with Dr. John Corboy, Dr. Mikael Simons, Dr. John DeLuca, and Dr. Stehen Krieger
12/15/2025
Episode 433: Our Most Important Conversations of 2025 with Dr. John Corboy, Dr. Mikael Simons, Dr. John DeLuca, and Dr. Stehen Krieger
As the year draws to a close, we wanted to share some of the most compelling conversations we've had over the past 12 months. And rather than make my own picks, we went through the hundreds of emails we've received over the past year from the RealTalk MS listener community to see which topics really connected with you. In this week's episode, you'll hear from four of the top MS experts in the world discussing the subjects you've told me are most important to you. First, we'll explore aging and MS with Dr. John Corboy, the principal investigator of the largest study designed to answer the question, "Once I turn 60, can I discontinue my disease-modifying therapies?" We'll talk about remyelination with the winner of the 2025 Barancik Prize for Innovation in Multiple Sclerosis Research, Dr. Mikael Simons. You'll hear our conversation with one of the world's top MS rehabilitation experts, Dr. John DeLuca, as we tackle one of the most disruptive MS symptoms -- fatigue. And we'll wrap up this episode by talking with clinician-scientist Dr. Stephen Krieger about the confusion around trying to reconcile the idea of progression independent of relapse activity (PIRA) with a diagnosis of relapsing-remitting MS. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Our most important conversations of 2025 :22 Dr. John Corboy discusses aging and MS 1:07 Dr. Mikael Simons discusses remyelination 10:54 Dr. John DeLuca discusses MS-related fatigue 19:20 Dr. Stephen Krieger discusses how the current course descriptors for MS (relapsing-remitting, secondary progressive, primary progressive) may no longer be working for doctors or patients 26:11 Share this episode 42:10 Next week's episode 42:30 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at SIGN UP: Become an MS Activist JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 433 Guests: Dr. John Corboy, Dr. Mikael Simons, Dr. John DeLuca, Dr. Stephen Krieger
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Special Episode: Guiding the Future of MS Care: MS21 Consensus Recommendations for Improving MS Care to Relieve the Burden of Disease
12/11/2025
Special Episode: Guiding the Future of MS Care: MS21 Consensus Recommendations for Improving MS Care to Relieve the Burden of Disease
This special episode of RealTalk MS is sponsored by EMD Serono and is only intended for a U.S. audience. EMD Serono is the healthcare business of Merck, KGaA, Darmstadt, Germany, in the United States and Canada. Please note this episode is only intended for a U.S. audience. In this special episode of RealTalk MS, Professor Elisabeth Celius and Amanda Montague join me to explore new consensus recommendations for the future of MS care from MS in the 21st Century. We'll hear what experts and people in the MS community think are the priorities to focus on to improve care and help lessen the burden of living with MS. Professor Elisabeth Celius is a consultant neurologist with a special focus on MS at Oslo University Hospital in Norway, where she is the group leader of the MS Research Group and also conducts epidemiological, genetic, and clinical research. Amanda Montague is a global thought leader and Interim President & CEO of the Multiple Sclerosis Association of America. Both Amanda and Elisabeth are active members of the MS in the 21st Century initiative, more commonly known as MS21. MS21 is a Merck KGaA, Darmstadt, Germany, initiative involving healthcare professionals, people with MS, and patient advocacy groups. To learn more about MS in the 21st Century, please visit .
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Episode 432: Working With a Health & Wellness Coach with Amy Behimer
12/08/2025
Episode 432: Working With a Health & Wellness Coach with Amy Behimer
Michael Jordan never won an NBA championship until he was paired with the right coach. Then, he won six. Could working with a coach change your MS journey? In this week's episode, health & wellness coach Amy Behimer explains what health coaching is all about and how working with a coach might impact someone living with MS. We're also sharing study results that show DMTs fail to manage MS-related pain. Then, we'll explain how a common misconception can lead to the wrong outcome for someone with MS. And we'll share study results showing that adhering to the Mediterranean or MIND diet improves cognitive performance among people living with MS. We'll also explain why this study raises as many questions as it seeks to answer. We have a lot to talk about! Are you ready for RealTalk MS??! Thank you! :22 This Week: What working with a health coach is all about 1:08 Study results show that disease-modifying therapies don't help manage MS-related pain (But are they supposed to???) 2:29 Study results show that adhering to the Mediterranean or MIND diet improves cognitive performance among people with MS (Or does it??) 5:13 Health & Wellness Coach Amy Behimer explains how someone living with MS could benefit from coaching 12:11 Share this episode 39:33 Next week's episode 39:53 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at DONATE: The National MS Society SIGN UP: Become an MS Activist STUDY: Phase 2 Clinical Trial for Moderna's EBV Vaccine and MS STUDY: Mediterranean and MIND Diet Patterns and Cognitive Performance in Multiple Sclerosis: A Cross-Sectional Analysis of the UK Multiple Sclerosis Register JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 432 Guests: Amy Behimer
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Special Episode: I'm the First Participant in a CAR-T Cell Therapy Clinical Trial with Jan Janisch-Hanzlik
12/04/2025
Special Episode: I'm the First Participant in a CAR-T Cell Therapy Clinical Trial with Jan Janisch-Hanzlik
Welcome to a RealTalk MS special series on MS clinical trials. This special series is made possible through a generous grant from Sanofi. In this final episode of this series, you'll meet Jan Janisch-Hanzlik. Jan lives with MS and is a participant in one of the clinical trials evaluating the safety and efficacy of CAR-T cell therapy for MS. In CAR-T cell therapy, blood is taken from the patient or a healthy donor, much as you would donate blood. This blood is sent to a lab, where the white blood cells, or T-cells, are separated out and reprogrammed to carry a receptor designed to fight a particular condition. This receptor is known as a chimeric antigen receptor, or CAR. Over several weeks in the lab, these fortified T-cells multiply until there are millions of them, then they're reintroduced to the patient by intravenous infusion. CAR-T cell therapy is already used to treat some blood cancers, and Jan is the first person in the world to receive this one-and-done treatment to treat MS. She's joining us to share her experience participating in the clinical trial and to give us an update on how she's doing following her treatment. This special episode of RealTalk MS is made possible by a generous grant from Sanofi. Sanofi has two ongoing Phase 3 clinical trials in MS studying Frexalimab, an investigational second-generation anti-CD40 ligand monoclonal antibody. If you are interested in learning more about these clinical trials, please visit SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the !
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Episode 431: When a Teenager Becomes a Caregiver For a Parent With MS with Michaela Janssen Pohl
12/01/2025
Episode 431: When a Teenager Becomes a Caregiver For a Parent With MS with Michaela Janssen Pohl
At the age of 14, Michaela Janssen Pohl became a caregiver for her mother, who lives with MS. I think most of us can agree that just being a teenager carries with it more than enough challenges. Those adolescent years are the years when just about everything in life starts changing. Imagine adding the responsibilities of being a caregiver to all the other things going on in a 14-year-old girl's life. Michaela joins me this week to explain how she found ways to survive and thrive in what can only be described as a challenging situation for any teenager. We'll also explain why you might want to think a little differently about Giving Tuesday this year. We're sharing all the details about the Phase 2 clinical trial focusing on Moderna's investigational Epstein-Barr vaccine and MS (and we'll explain why that might turn out to be important!) We're talking about how MS impacts women's health issues with this year's winner of the Rachel Horne Prize for Women's Research in Multiple Sclerosis, Dr. Kristen Krysko. And we're sharing the results of the Phase 2 clinical trial for PIPE-307, an investigational remyelination therapy. We have a lot to talk about! Are you ready for RealTalk MS??! It's Giving Tuesday (and why that matters more this year than ever before) :22 This Week: Becoming a caregiver for a parent with MS when you're 14 years old 3:27 A clinical trial focused on an EBV vaccine and MS is recruiting participants 4:25 Dr. Kristen Krysko discusses MS and women's health issues 7:52 Results from the Phase 2 clinical trial for PIPE-307 remyelination therapy 13:48 Michaela Janssen Pohl shares her story of becoming a caregiver at the age of 14 16:55 Share this episode 33:20 Next week's episode 33:40 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at DONATE: The National MS Society SIGN UP: Become an MS Activist PARTICIPATE: Phase 2 Clinical Trial for Moderna's EBV Vaccine and MS Email: JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 431 Guests: Dr. Kristen Krysko, Michaela Janssen Pohl
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Episode 430: Navigating Winter Weather When You're Living with MS with Dr. James Stark
11/24/2025
Episode 430: Navigating Winter Weather When You're Living with MS with Dr. James Stark
Almost everyone with MS is aware of their sensitivity to heat. But cold weather presents a whole different set of challenges that we don't always think about. This week, I'm talking with Dr. James Stark about safely navigating cold-weather conditions when you're living with MS. Dr. Stark is the Senior Attending Neurologist and Associate Medical Director at the International Multiple Sclerosis Management Practice. And he's sharing tips for staying safe and healthy when the temperature starts to drop. The FDA has just approved a new generic DMT, and the first biosimilar for MS is hitting the market. We'll tell you about these new disease-modifying therapy options, and we'll bring you up to speed on what biosimilars are all about. I ran into Dr. Robert Fox at ECTRIMS, the world's largest MS research conference. And, in a brief conversation, Dr. Fox provided a great overview of the MS research landscape. You won't want to miss this conversation! If you missed the International Progressive MS Alliance's global webcast, Hidden Potential: How Existing Drugs Could Transform MS Treatment, you can still catch the video replay. We're sharing all the details. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: There's a lot to still be thankful for :22 Your opportunity to support the organization that supports you 2:03 What you need to know about the new generic and biosimilar disease-modifying therapies 9:24 The Cleveland Clinic's Dr. Robert Fox shares an overview of the MS research landscape 10:29 Catch the International Progressive MS Alliance Global Webcast video replay 22:41 Dr. James Stark shares tips for navigating winter weather when you're living with MS 23:27 Share this episode 35:14 Next week's episode 35:35 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at DONATE to the National MS Society SIGN UP: Become an MS Activist WATCH: International Progressive MS Alliance Global Webcast Replay LISTEN: RealTalk MS EP. 315: Understanding Generic and Biosimilar Drugs for MS with Dr. Jiwon Oh VISIT: Mark Cuban Cost Plus Drugs JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 430 Guests: Dr. Robert Fox, Dr. James Stark
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Special Episode: Participating in MS Research with Chiquita Shepard-Knight and Earl Sneed
11/20/2025
Special Episode: Participating in MS Research with Chiquita Shepard-Knight and Earl Sneed
Welcome to a RealTalk MS special series on MS clinical trials. This special series is made possible through a generous grant from Sanofi. In today's episode, you'll meet two participants from the TEAMS Study, a research study at the University of Illinois Chicago's UI Health, in conjunction with the University of Alabama Birmingham School of Public Health. TEAAMS is an acronym for Targeted Exercise for African-Americans with Multiple Sclerosis. And the study's research team analyzed the effects of a remotely delivered, racially tailored exercise training program among African Americans with MS living in low-income areas of the Southeastern United States, including Alabama, Georgia, Mississippi, North Carolina, South Carolina, Louisiana, Arkansas, and Tennessee. This is a part of the country that doesn't have many primary care or MS clinics that provide full exercise and rehabilitation services for patients with MS. The TEAMMS study consists of two 16-week exercise programs, completed 3 days per week at home. One exercise program combines aerobic and resistance training, while the other focuses on stretching and flexibility. Study participants were randomly assigned to one of the two programs, and all of the materials to complete each program, like yoga mats, resistance bands, and training manuals, were provided. And every study participant receives a $90 gift card in compensation for completing the program. The study's research team hypothesizes that completing the TEAAMS program would improve walking, reduce symptoms of fatigue, anxiety, depression, and pain, and enhance quality of life. This special episode of RealTalk MS is made possible by a generous grant from Sanofi. Sanofi has two ongoing Phase 3 clinical trials in MS studying Frexalimab, an investigational second-generation anti-CD40 ligand monoclonal antibody. If you are interested in learning more about these clinical trials, please visit SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the !
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Episode 429: Caring for Your Partner with MS While Holding Down a Full-Time Job with Diana Grazio
11/17/2025
Episode 429: Caring for Your Partner with MS While Holding Down a Full-Time Job with Diana Grazio
Being a caregiver for a loved one with MS isn't an easy job. And, while it may consume hours of your time, often, it's not your only job. Many caregivers are the only family members bringing in an income. So, in addition to their caregiving responsibilities, they may also be facing the responsibilities that go along with holding down a full-time job. This week, Diana Grazio joins me to discuss how she balances her roles and responsibilities as her partner's caregiver while holding down a full-time job. You have online opportunities tomorrow! Participate in the National MS Society's Hispanic LatinX MS Experience Summit, or catch the International Progressive MS Alliance's global webcast, How Existing Drugs Could Transform MS Treatment. We have all the info for you to register for either or both! If you purchase your health insurance through the ACA Healthcare Marketplace, you've probably already been notified that your premiums will skyrocket in 2026. MS Activist, Sarah Quezada, shares how those premium increases will affect her family. Roche has announced the outcomes of Phase 3 clinical trials for Fenebrutinib and Relapsing MS, and Primary Progressive MS. It's positive news, and we have the details! Could nanoparticles penetrate the blood-brain barrier and deliver anti-inflammatory medication directly to the central nervous system? University of Illinois researchers say yes! We're sharing the details. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: It's National Family Caregiver Month :22 The MS Care Partner Connection :34 The National MS Society is hosting the Hispanic LatinX MS Experience Summit TOMORROW! 2:20 The International Progressive MS Alliance Global Webcast is TOMORROW! 2:51 Sarah Quezada shares how astronomical increases in ACA health insurance premiums will affect her family 3:46 Roche announces outcomes for Phase 3 clinical trials for Fenebrutinib and Relapsing MS, and Primary Progressive MS 11:59 Could nanoparticles penetrate the blood-brain barrier and deliver anti-inflammatory medication directly to the central nervous system? 13:43 Diana Grazio discusses how she manages her role as a caregiver while holding down a full-time job 16:07 Share this episode 29:10 Next week's episode 29:30 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Online Survey SIGN UP: Become an MS Activist REGISTER: The Hispanic LatinX MS Experience Summit REGISTER: International Progressive MS Alliance Global Webcast VISIT: The MS Care Partner Connection STUDY: Nanoparticle-Boosted Myeloid-Derived Suppressor Cell Therapy for Immune Reprogramming in Multiple Sclerosis JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 429 Guests: Sarah Quezada, Diana Grazio
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Episode 428: The Effects of Smoking, Consuming Alcohol, and Consuming Caffeine on Your MS with Dr. Barbara Giesser
11/10/2025
Episode 428: The Effects of Smoking, Consuming Alcohol, and Consuming Caffeine on Your MS with Dr. Barbara Giesser
As researchers continue to learn about MS, it becomes clear that you can change the trajectory of your MS journey and improve your quality of life by making smart lifestyle choices. Quitting smoking and watching your alcohol and caffeine consumption are smart choices for everyone, and they can pay especially big dividends if you're living with MS. This week, Dr. Barbara Giesser discusses how smoking, consuming alcohol, and consuming caffeine can impact your MS. We're also sharing the details about the Black MS Experience Summit taking place on November 12th, and the Hispanic LatinX MS Experience Summit taking place on November 19th. We'll tell you about a study that revealed what may be a novel way of stimulating remyelination. You'll meet Dr. Arman Eshaghi and hear about how artificial intelligence may impact your future MRI exam. We'll share study results that show that carbohydrate consumption may increase the risk of an individual developing MS. And we'll tell you about a study that looked at the connection between starting a disease-modifying therapy early and quality of life related to cognitive function and fatigue. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: What you need to know about how smoking, consuming alcohol, and consuming caffeine impact your MS :22 The Black MS Experience Summit is TOMORROW! 1:32 The National MS Society is hosting the Hispanic LatinX MS Experience Summit on Nov 19th 2:33 Study results indicate the path to myelin repair may require subtraction, not addition 3:04 Dr. Arman Eshaghi discusses how AI may change how MRI scans are interpreted 5:12 Study results show a connection between carbohydrate intake and MS risk 15:10 Study results show how starting a DMT early impacts quality of life related to cognitive function and fatigue among people with MS 17:55 Dr. Barbara Giesser discusses how smoking, consuming alcohol, and consuming caffeine impact people living with MS 21:38 Share this episode 31:07 Next week's episode 31:27 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Online Survey SIGN UP: Become an MS Activist WATCH: The RealTalk MS ECTRIMS Extra Conversations video playlist on YouTube STUDY: Gt2fi-Encoded Transcription Factor Tfii-i Regulates Myelin Via Sox10 and Mbp Regulatory Elements STUDY: Association Between Dietary Carbohydrate Intake and Multiple Sclerosis Risk: A Large-Scale Cohort Study STUDY: Self-Reported Quality of Life Related to Cognitive Function and Fatigue in Adults with Multiple Sclerosis REGISTER: The Black MS Experience Summit REGISTER: The Hispanic LatinX MS Experience Summit JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 428 Guests: Dr. Arman Eshaghi, Dr. Barbara Giesser
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Episode 427: Science-Based Vaccine Guidance for People Living with MS with Dr. Lisa Doggett
11/03/2025
Episode 427: Science-Based Vaccine Guidance for People Living with MS with Dr. Lisa Doggett
When you're living with a chronic condition like MS, you want to be sure you're doing everything you can to preserve and promote good health. And, right now, you may be feeling confused about whether you should be getting vaccinated, and which vaccines are safe. It's understandable. Unfortunately, there's a lot of confusing information about vaccines and vaccinations floating around out there. This week, Dr. Lisa Doggett helps us get past all the unnecessary noise and hysteria and reviews the science-based vaccine recommendations for people living with MS. We're also talking about the historic meeting that took place last week between the FDA and people affected by MS. We're sharing dramatic results from the largest study of its kind that measured the true impact of MS on quality of life. And we're giving you all the details about the National MS Society's upcoming Black MS Experience Summit. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Reliable, science-based vaccine guidance for people living with MS :22 An historic meeting between the FDA and the MS community 1:17 The largest study of its kind shows the true impact of MS on quality of life 3:13 The National MS Society is hosting the Black MS Experience Summit on Nov 12th 4:40 Dr. Lisa Doggett covers everything you need to know about vaccines and MS 6:22 Share this episode 26:10 Next week's episode 26:30 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Online Survey SIGN UP: Become an MS Activist WATCH: The RealTalk MS ECTRIMS Extra Conversations video playlist on YouTube STUDY: EQ-5D-5L In Multiple Sclerosis: Estimated Utility Values, Minimal (Clinically) Important Changes, and Direct and Indirect Influences Over Time REGISTER: The Black MS Experience Summit JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 427 Guests: Dr. Lisa Doggett
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Episode 426: Fighting Her Way Through the Health Insurance Maze with Cassandra Ashby
10/27/2025
Episode 426: Fighting Her Way Through the Health Insurance Maze with Cassandra Ashby
Some disease-modifying therapies can change the trajectory of your MS journey. But gaining access to those medications isn't always as easy or straightforward as it should be. In the United States, insurance companies are most often the gatekeepers to prescription medications. This week, Cassandra Ashby shares a story that many of you may already be too familiar with, as she takes us through her family's long, hard, and confusing struggle to get the DMT that her newly-diagnosed daughter's neurologist prescribed. I We're also talking about the game-changing results of a study that demonstrate MS-related damage to the brain occurs years before the very first symptom becomes apparent. And we're explaining why this opens the door to treatment that may stop MS symptoms from even developing. We're giving you a heads-up about changes to the way health records for MS patients are being coded, and how these changes are already creating obstacles to accessing the disease-modifying therapy that you may have been taking for months or years. And we're reminding you that you still have time to register to participate virtually in tomorrow's historic meeting between people with MS and the FDA We have a lot to talk about! Are you ready for RealTalk MS??! This Week: The sometimes overwhelming challenge of gaining access to the disease-modifying therapy that's been prescribed by your MS Specialist :22 Study results demonstrate MS-related brain damage occurs years before MS symptoms 1:22 What are ICD-10 codes, and why do the latest changes to these codes pose potential challenges for people living with MS? 5:52 You can participate virtually in tomorrow's meeting between people with MS and the FDA 9:23 Cassandra Ashby shares her family's long, hard, and confusing struggle with their insurance company 10:56 Share this episode 31:06 Next week's episode 31:26 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA SIGN UP: Become an MS Activist STUDY: Myelin Injury Precedes Axonal Injury and Symptomatic Onset in Multiple Sclerosis WATCH: The RealTalk MS ECTRIMS Extra Conversations video playlist on YouTube JOIN: The RealTalk MS Facebook Group REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 426 Guests: Cassandra Ashby
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Episode 425: The ECTRIMS 2025 Deep Dive with Dr. Bruce Bebo
10/20/2025
Episode 425: The ECTRIMS 2025 Deep Dive with Dr. Bruce Bebo
Just about a month ago, 9,600 researchers, clinicians, and representatives from patient advocacy organizations gathered in Barcelona for the European Committee on Treatment and Research in MS annual scientific congress, better known as ECTRIMS, the largest MS research conference in the world. Now that he's had an opportunity to review his notes and digest all of the science presented at ECTRIMS 2025, Dr. Bruce Bebo, the National MS Society's Executive Vice-President of Research, returns to the podcast to take us on a deep dive covering some of the most important research presented this year. We're also talking about next-generation CAR T-cell therapy for MS, and we'll explain why it's such exciting news. We're sharing details about a DNA-based therapy for overactive bladder that just received fast-track status from the FDA. We'll tell you about a new effort to develop a simple blood test that will detect MS progression. We have some news to share about the RealTalk MS app. And we want to remind you to check out our ECTRIMS Extra Conversations video playlist on the RealTalk MS YouTube channel! We have a lot to talk about! Are you ready for RealTalk MS??! This Week: A deep dive into the research presented at ECTRIMS 2025 :22 Kernal Biologics received $48 million grant for the next-generation CAR T-Cell therapy 2:35 FDA grants fast track designation to DNA-based therapy to treat overactive bladder 6:02 Octave Bioscience receives grant to develop a blood test to detect MS progression 8:30 News about our app 9:42 Have you checked out our ECTRIMS Extra Conversations YouTube playlist? 10:30 Dr. Bruce Bebo discusses some of the most important research presented at ECTRIMS 2025 11:06 Share this episode 32:26 Next week's episode 32:47 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA SIGN UP: Become an MS Activist LISTEN: RealTalk MS Ep 422: From ECTRIMS 2025 with Dr. Bruce Bebo and Kristine Werner Ozug WATCH: The RealTalk MS ECTRIMS Extra Conversations video playlist on YouTube JOIN: The RealTalk MS Facebook Group DOWNLOAD: The RealTalk MS App for iOS Devices DOWNLOAD: The RealTalk MS App for Android Devices REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 425 Guests: Dr. Bruce Bebo
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Episode 424: I'm a Participant in a Clinical Trial for CAR-T Cell Therapy and MS with Jan Janisch-Hanzlik
10/13/2025
Episode 424: I'm a Participant in a Clinical Trial for CAR-T Cell Therapy and MS with Jan Janisch-Hanzlik
Jan Janisch-Hanzlik lives with MS and is a participant in one of the clinical trials evaluating the safety and efficacy of CAR-T cell therapy for MS. Jan is the first person in the world to receive this one-and-done treatment, and this week, she's joining me to share her experience participating in the clinical trial. But you'll be especially interested in hearing how CAR-T cell therapy has impacted Jan's MS. Open enrollment for people with Medicare and for those who get their health insurance through the ACA healthcare.gov Marketplace begins this week, and we're talking about some of the reasons you want to pay particular attention to your 2026 health insurance options. As the U.S. federal government shutdown enters its third week, we're reviewing some of the ways that the shutdown may affect someone living with MS. And we're giving you a reminder about how you can add your voice and share your story of living with MS with the FDA by participating in the Shaping Tomorrow Together initiative. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: A first-hand account of an important clinical trial, open enrollment begins, and how the government shutdown may affect people with MS :22 Open enrollment for Medicare and Marketplace enrolees begins :22 How the federal government shutdown could affect people living with MS 4:29 Your opportunity to tell the FDA what it's like to live with MS 8:57 Jan Janisch-Hanzlik shares her experience participating in a CAR-T cell therapy clinical trial, and how the treatment has impacted her MS 11:28 Share this episode 31:38 Next week's episode 31:57 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA SIGN UP: Become an MS Activist JOIN: The RealTalk MS Facebook Group DOWNLOAD: The RealTalk MS App for iOS Devices DOWNLOAD: The RealTalk MS App for Android Devices REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 424 Guest: Jan Janisch-Hanzlik
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Special Episode: The Risks and Rewards of Participating in Clinical Trials with Dr. Kathy Zackowski and Mimi Brown
10/10/2025
Special Episode: The Risks and Rewards of Participating in Clinical Trials with Dr. Kathy Zackowski and Mimi Brown
Welcome to a RealTalk MS special series on MS clinical trials. This special series is made possible through a generous grant from Sanofi. In today's episode, we're exploring the risks and rewards of participating in a clinical trial with Dr. Kathy Zackowski and Mimi Brown. Dr. Zackowski is the Associate Vice President of Research at the National MS Society, and she's going to offer an overview of the risks and benefits that you'll want to weigh in considering participating in a clinical trial. Mimi Brown lives with primary progressive MS, and Mimi is going to share her own experience as a participant in multiple clinical trials. This special episode of RealTalk MS has been made possible through a generous grant from Sanofi. Sanofi has two ongoing Phase 3 clinical trials in MS studying Frexalimab, an investigational second-generation anti-CD40 ligand monoclonal antibody. If you are interested in learning more about these clinical trials, please visit SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the !
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Episode 423: Understanding Infections and MS with Dr. Robert Fox
10/06/2025
Episode 423: Understanding Infections and MS with Dr. Robert Fox
From the earliest days of the COVID-19 pandemic, people living with MS have been justifiably concerned about how a COVID-19 infection might impact their MS. As the new "Stratus" strain of COVID-19 is currently surging in the United States, research is providing answers we didn't have five years ago. Dr. Robert Fox, the Managing Director of the NARCOMS Patient Registry, joins me to discuss how COVID-19 infections and other infections impact people with MS. As ECTRIMS, the world's largest MS research conference, approached, many attendees anticipated the FDA's decision on whether to approve Tolebrutinib, the first in a new category of disease-modifying therapies. Instead, the FDA has requested additional time for its review. We'll fill you in on the FDA's new target action date, and explain why there's strong interest in this particular disease-modifying therapy. We know there's a specific gene that increases the risk of someone developing MS. But have you ever wondered where that gene came from, or why it exists at all? At ECTRIMS, Professor Lars Fugger took us on a journey 5,000 years into the past to explain its origin. When I spoke with him, Professor Fugger also explained how events from ancient history are still affecting the risk of developing MS today. You won't want to miss this compelling conversation! At ECTRIMS, I also caught up with Jason Tardio, the President, and Dr. Andreas Muehler, the Chief Medical Officer, from Immunic Therapeutics. We talked about how their investigative drug, vidofludimus calcium, could potentially benefit people with MS by combating inflammation, protecting the nervous system, and offering antiviral benefits. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Infections and MS, and more from ECTRIMS 2025! :22 FDA extends its review of Tolebrutinib 1:42 From ECTRIMS: Professor Lars Fugger discusses the origin of the gene that increases an individual's risk of developing MS 4:11 From ECTRIMS: Jason Tardio, President, and Dr. Andreas Muehler, Chief Medical Officer, at Immunic Therapeutics, discuss how vidofludimus calcium could potentially benefit people with MS 11:22 Dr. Robert Fox discusses what the research reveals about how COVID-19 infections and other infections impact people living with MS 16:34 Share this episode 32:00 Next week's episode 32:19 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA SIGN UP: Become an MS Activist JOIN: The RealTalk MS Facebook Group DOWNLOAD: The RealTalk MS App for iOS Devices DOWNLOAD: The RealTalk MS App for Android Devices REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 423 Guests: Professor Lars Fugger, Jason Tardio, Dr. Andreas Meuhler, and Dr. Robert Fox
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Episode 422: From ECTRIMS 2025 with Dr. Bruce Bebo and Kristine Werner Ozug
09/29/2025
Episode 422: From ECTRIMS 2025 with Dr. Bruce Bebo and Kristine Werner Ozug
Last week, over 9600 MS researchers and clinicians gathered in Barcelona for the European Committee for Treatment and Research in Multiple Sclerosis annual scientific congress -- ECTRIMS 2025. Minutes after the conference adjourned, in what has become an annual tradition, Dr. Bruce Bebo, the Executive Vice President of Research at the National MS Society, joined me to share his initial thoughts on the science presented at the meeting. Then, Kristine Werner Ozug, a member of the RealTalk MS team who lives with MS, joined me to share her perspective on three non-stop days of presentations, news, and announcements. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: It's all about ECTRIMS 2025! :22 The Executive Vice President of Research at the National MS Society, Dr. Bruce Bebo, shares his initial impressions of ECTRIMS 2025 1:17 As someone who lives with MS, Kristine Werner Ozug shares her thoughts on ECTRIMS 2025 10:03 Share this episode 22:30 Next week's episode 22:50 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA SIGN UP: Become an MS Activist JOIN: The RealTalk MS Facebook Group DOWNLOAD: The RealTalk MS App for iOS Devices DOWNLOAD: The RealTalk MS App for Android Devices REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 422 Guests: Dr. Bruce Bebo and Kristine Werner Ozug
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Episode 421: Optimizing Your Brain Health with Nurse Practitioner Erin Wilkinson
09/22/2025
Episode 421: Optimizing Your Brain Health with Nurse Practitioner Erin Wilkinson
Happy birthday to us! RealTalk MS is 8 years old today! It's hard for me to believe that the podcast I launched in 2017, with the goal of one day reaching 300 listeners, today reaches thousands of people living with MS, their care partners, MS researchers, and clinicians in more than 100 countries. So, let me start this week's show notes with a profound thank you to each of you for being an important part of the RealTalk MS listener community. Your ongoing engagement is a constant reminder that our podcast is a two-way conversation. And I'm looking forward to continuing the conversation until we can talk about MS in the past tense. MS can affect memory, attention, and processing speed. But proactive strategies can help preserve your cognitive function and quality of life. Erin Wilkinson, a nurse practitioner in the Multiple Sclerosis Department of the Cleveland Clinic Lou Ruvo Center for Brain Health, is joining me to help us better understand the relationship between MS and brain health and to share strategies for preserving and even improving brain health. You'll also meet Jan Bonville, a consultant, speaker, writer, and advocate for inclusive travel and patient empowerment. Jan has lived with MS for twenty years, and our conversation focused on resilience, empowerment, and self-advocacy. As you will hear, these are things that Jan lives every day. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Happy birthday to us and greetings from ECTRIMS! :22 MS advocate Jan Bonville discusses resilience, empowerment, and self-advocacy 4:40 Nurse Practitioner Erin Wilkinson shares strategies for optimizing your brain health 23:03 Share this episode 41:01 Next week's episode 41:21 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA SIGN UP: Become an MS Activist LISTEN: RealTalk MS Episode 416: The Updated McDonald Diagnostic Criteria for MS with Dr. Andrew Solomon VIDEO: Dr. Robert Fox explains the results of the Phase 3 clinical trial for Tolebrutinib and Non-relapsing secondary progressive MS JOIN: The RealTalk MS Facebook Group DOWNLOAD: The RealTalk MS App for iOS Devices DOWNLOAD: The RealTalk MS App for Android Devices REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 421 Guests: Jan Bonville and NP Erin Wilkinson
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Special Episode: Dr. Aaron Boster Explains MS Clinical Trials
09/17/2025
Special Episode: Dr. Aaron Boster Explains MS Clinical Trials
You're living with MS, and maybe you're thinking about participating in an MS clinical trial. But how do they work? Are they safe? What's the difference between Phase 1, 2, and 3 trials? What are the real patient risks and benefits of participating in a clinical trial? In this special episode of RealTalk MS, we're getting answers to those questions and so much more from my guest, Dr. Aaron Boster. Dr. Boster is the founder of the Boster Center for Multiple Sclerosis in Columbus, Ohio, where he brings over 20 years of experience as an MS clinician. Dr. Boster has also participated in more than 65 clinical trials. This special episode of RealTalk MS has been made possible through a generous grant from Sanofi. Sanofi has two ongoing Phase 3 clinical trials in MS studying Frexalimab, an investigational second-generation anti-CD40 ligand monoclonal antibody. If you are interested in learning more about these clinical trials, please visit SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the !
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Episode 420: A DIY Kit for Improving Your MS Journey with Julie Polisena
09/15/2025
Episode 420: A DIY Kit for Improving Your MS Journey with Julie Polisena
Disease-modifying therapies are the cornerstone of MS treatment, but they're not the only piece of the puzzle. Beyond prescription medications, self-care that includes making healthy lifestyle choices can significantly improve your quality of life with MS. Julie Polisena knows this firsthand. Julie lives with MS, and in a recent blog post, she shared a comprehensive list of the lifestyle changes that have improved her quality of life with MS. Julie joins us today to discuss some of the most impactful changes you can make to start your own journey toward better health and wellness. We're also diving into the science behind some of the most talked-about diets for MS. We're breaking down the research on the Mediterranean diet, the Keto diet, the Wahls Diet, the Swank Diet, a gluten-free diet, and intermittent fasting, giving you an overview of the studies that have measured their impact on MS. We're discussing the latest developments in the ongoing scrutiny of pharmacy benefit managers (PBMs). There's significant pending legal action and a congressional investigation targeting PBMs, the powerful and secretive middlemen in the prescription drug supply chain. And we'll tell you how they've profited at the expense of millions of people with chronic illnesses, including people living with MS. We'll tell you about a clinical trial that's testing an injectable formulation of Briumvi. You'll hear about a promising new strategy for myelin repair. And we'll remind you about a warning from the FDA and Health Canada about glatiramer acetate (Copaxone). We have a lot to talk about! Are you ready for RealTalk MS??! This Week: A DIY approach to improving your MS journey :22 A roundup of studies that focused on popular diets for people with MS 1:53 Congress and the FTC have pharmacy benefit managers in their sites 7:32 TG Therapeutics is testing an injectable form of Briumvi 9:32 A research team has developed a novel remyelination strategy 11:03 A warning about glatiramer acetate has been issued 14:08 Julie Polisena discusses lifestyle changes that can make a difference in your quality of life 16:58 Share this episode 33:24 Next week's episode 33:43 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA SIGN UP: Become an MS Activist READ: Small Changes, Big Impact: Managing My MS Through Lifestyle Changes https://mscanada.ca/find-support/blog/small-changes-big-impact-managing-my-ms-through-lifestyle-change STUDY: The Role of Nutrition and Physical Activity in Modulating Disease Progression and Quality of Life in Multiple Sclerosis STUDY: Transient Gene Melting Governs the Timing of Oligodendrocyte Maturation REVIEW: Copaxone, Glatopa (Glatiramer Acetate) FDA Drug Safety Communication JOIN: The RealTalk MS Facebook Group DOWNLOAD: The RealTalk MS App for iOS Devices DOWNLOAD: The RealTalk MS App for Android Devices REVIEW: Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 420 Guest: Julie Polisena
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Episode 419: A Whole-Person Health Approach to MS Care with Dr. Lynne Shinto
09/08/2025
Episode 419: A Whole-Person Health Approach to MS Care with Dr. Lynne Shinto
Some people living with MS adhere to a treatment plan based exclusively on what we might consider traditional medicine. Others opt for alternative treatments. And, still, others take a whole-person health approach, blending integrative medicine with traditional treatments designed to support an individual's mind and body. Dr. Lynne Shinto joins me to discuss how a whole-person health approach can transform living with MS. Dr. Shinto is a Professor of Neurology and an MS Specialist at the Center for Women's Health at Oregon Health and Science University. We're also sharing some encouraging news about funding for the National Institutes of Health in 2026. We'll explain the research that has led to the identification of a new and quite different subtype of MS. We'll tell you about this year's winner of the Rachel Horne Prize for Women's Research in Multiple Sclerosis. The National MS Society's virtual program, New to MS: Navigating Your Journey, takes place in just two days. We have all the details! We have a lot to talk about! Are you ready for RealTalk MS??! This Week: A whole-person health approach to MS care :22 House Republicans reject President Trump's $20 billion cut to 2026 NIH funding 1:26 Have researchers identified a new MS subtype? 4:16 This year's winner of the Rachel Horne Prize for Women's Research in Multiple Sclerosis 8:27 We're two days away from the National MS Society's New to MS: Navigating Your Journey virtual program 9:53 Dr. Lynne Shinto discusses how taking a whole-person approach to MS care can transform your MS journey 12:04 Share this episode 31:41 Next week's episode 32:01 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA SIGN UP: Become an MS Activist STUDY: Large-Scale Online Assessment Uncovers a Distinct Multiple Sclerosis Subtype with Selective Cognitive Impairment REGISTER: New To MS: Navigating Your Journey Join the RealTalk MS Facebook Group Download the RealTalk MS App for iOS Devices Download the RealTalk MS App for Android Devices Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 419 Guest: Dr. Lynne Shinto
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Episode 418: The Importance of Developing a Growth Mindset When You're Living With MS with Dr. Mirian Franco
09/01/2025
Episode 418: The Importance of Developing a Growth Mindset When You're Living With MS with Dr. Mirian Franco
Living with MS means living with uncertainty, possible physical disability or cognitive dysfunction, bouts of crushing fatigue, mood changes, and let's not forget the very real irritation of well-meaning people telling you how healthy you look. Just processing the world around you can feel challenging. In this episode, psychologist Dr. Miriam Franco joins me to discuss how developing a growth mindset can make all the difference in how you experience your MS journey. We're also sharing a real-world example of how the drastic cuts in federal funding are already impacting MS care. We'll tell you about the first country in the world to approve Tolebrutinib, a new disease-modifying therapy for nonrelapsing secondary progressive MS. And we'll explain why people are particularly excited about this medication. We'll share details about the MS Clinical Imaging and Data Resource that's been launched by the International Progressive MS Alliance. We'll tell you how and where to catch the MS Standup Comedy Benefit next Monday in New York. And we're reminding you about your opportunity to impact future MS therapies by helping the FDA better understand what living with MS is really like. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Developing a growth mindset :22 How those federal research funding cuts are impacting MS patient care 1:30 United Arab Emirates becomes the first country in the world to approve Tolebrutinib for nonrelapsing secondary progressive MS 5:05 The International Progressive MS Alliance launches an MS Clinical Imaging and Data Resource open to the MS research community 8:32 The MS Standup Comedy Benefit takes place next Monday in New York 10:15 Add your voice and participate in the Shaping Tomorrow Together initiative 11:04 Dr. Miriam Franco discusses what it means to have a growth mindset when you're living with MS 14:50 Share this episode 34:11 Next week's episode 34:31 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA VIDEO: Dr. Robert Fox, Principal Investigator in the Phase 3 Clinical Trial for Tolebrutinib and Secondary Progressive MS VIDEO: Dr. Jiwon Oh, Principal Investigator in the Phase 3 Clinical Trial for Tolebrutinib and Relapsing-Remitting MS The International Progressive MS Alliance Clinical Imaging and Data Resource ATTEND: MS Stand-Up Comedy Benefit Join the RealTalk MS Facebook Group Download the RealTalk MS App for iOS Devices Download the RealTalk MS App for Android Devices Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 418 Guest: Dr. Miriam Franco
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Episode 417: Music and the Body with Emmy Award-Winning Composer Jeff Beal
08/25/2025
Episode 417: Music and the Body with Emmy Award-Winning Composer Jeff Beal
If you've watched the critically acclaimed series, House of Cards, on Netflix, or the OCD detective series, Monk, on the USA Network, you've already listened to some of five-time Emmy award-winning composer Jeff Beal's work. This week, Jeff joins me to discuss his journey as an artist and as someone living with MS. We're also sharing all the details about the free event taking place at the Broad Stage in Santa Monica, California, on September 1, when Jeff joins conductor Leonard Slatkin and the Los Angeles Chamber Orchestra for a free concert featuring three of Jeff's works, including a world premiere! We're also explaining a newly introduced AI-based model of MS that replaces the MS subtypes (relapsing-remitting, secondary progressive, primary progressive) with a continuum that tracks four different states. We'll tell you about a study that identified specific gut bacteria that may determine whether an individual is susceptible to MS. And we'll share the details of a study that identified the first genetic marker that can accurately predict how someone will respond to a disease-modifying therapy. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Emmy award-winning composer Jeff Beal discusses his work and his MS journey :22 An AI-based model of MS 1:18 A study identifies specific gut bacteria that may be linked to MS susceptibility 4:49 A study identifies the first genetic marker for accurately predicting an individual's response to MS treatment 6:29 Composer Jeff Beal discusses his journey as an artist and as someone living with MS 9:57 Share this episode 30:36 Coming next week 30:56 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA ATTEND: Music + The Body An AI-Driven Reclassification of Multiple Sclerosis Progression STUDY: Multiple Sclerosis and Gut Microbiota: Lachnospiraceae From the Ileum of MS Twins Trigger MS-Like Disease in Germfree Transgenic Mice -- An Unbiased Functional Study PARTICIPATE: International MS Microbiome Study STUDY: HLA-A*03:01 As Predictive Genetic Biomarker for Glatiramer Acetate Treatment Response in Multiple Sclerosis: A Retrospective Cohort Analysis Join the RealTalk MS Facebook Group Download the RealTalk MS App for iOS Devices Download the RealTalk MS App for Android Devices Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 417 Guest: Jeff Beal
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Episode 416: The Updated McDonald Diagnostic Criteria for MS with Dr. Andrew Solomon
08/18/2025
Episode 416: The Updated McDonald Diagnostic Criteria for MS with Dr. Andrew Solomon
Since 2001, clinicians have relied on the McDonald Diagnostic Criteria as the gold standard for diagnosing someone with multiple sclerosis. As science continues to add to our understanding of MS, the McDonald Criteria have been updated in 2005, 2010, 2017, and most recently in 2024. This latest iteration of the McDonald criteria will be published in September, and today, Dr. Andrew Solomon is giving us a preview of what these changes are, what they mean, and how they're going to improve the process of diagnosing someone with MS. We'll also share results of a study that show MS may actually start 15 years before someone experiences their first MS symptom. We'll tell you about a study that shows a decline in the number of people with MS who are progressing to secondary progressive MS. We'll give you all the details so you can participate in the Shaping Tomorrow Together initiative with the FDA. And we'll remind you that Burgers to Beat MS Day is just two days away! We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Updated criteria for diagnosing MS :22 Study results show that MS actually starts many years before the first symptom 1:21 Study shows a decline in the number of people progressing to secondary progressive MS 7:40 A unique opportunity for you to impact future treatments and share your experience of living with MS with the FDA 9:51 We're just 2 days away from Burgers to Beat MS Day! 13:06 Dr. Andrew Solomon shares a preview of the updated McDonald Diagnostic Criteria for MS 14:40 Share this episode 26:20 Coming next week 26:41 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at PARTICIPATE: Take the Shaping Tomorrow Together Survey REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA STUDY: Health Care Use Before Multiple Sclerosis Symptom Onset STUDY: Health Care Use Before Multiple Sclerosis Symptom Onset (PLAIN ENGLISH VERSION) STUDY: Multiple Sclerosis From Onset to Secondary Progression: A 30-Year Italian Register Study DONATE: Burgers To Beat MS Join the RealTalk MS Facebook Group Download the RealTalk MS App for iOS Devices Download the RealTalk MS App for Android Devices Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 416 Guest: Dr. Andrew Solomon
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Episode 415: Your Money -- Ways to Earn and Hold Onto More of It When You're Living with MS with Beth Scott and Paula Cole
08/11/2025
Episode 415: Your Money -- Ways to Earn and Hold Onto More of It When You're Living with MS with Beth Scott and Paula Cole
Living with MS is expensive. Very expensive. It's estimated that the average cost of living with MS is over $88,000 per year. How, in the midst of financial stress and uncertainty, can you formulate a financial plan that takes MS into account? Paula Cole lives with MS, and she also lives with a lot of financial planning savvy. Paula joins the podcast to share tips and strategies for establishing a personal financial plan for you and your family -- even while you're coping with MS. And Beth Scott, the director of case management at the Patient Advocate Foundation, joins us to explain how you can take advantage of work incentive programs that allow an individual to keep working or even try returning to work while they're receiving Social Security Disability cash benefits. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Ways to earn and hold onto more money when you're living with MS :22 Beth Scott explains how you can benefit from work incentive programs while you're receiving Social Security Disability cash benefits :35 Paula Cole shares tips and strategies for establishing a personal financial plan for you and your family when you're living with MS 12:48 Share this episode 27:47 Next Week: The new criteria for diagnosing MS 28:07 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at Become an MS Activist Join the RealTalk MS Facebook Group Download the RealTalk MS App for iOS Devices Download the RealTalk MS App for Android Devices Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 415 Guests: Beth Scott, Paula Cole
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Episode 414: Finding Peace in the Midst of Uncertainty with Andrea Arzt, LCSW, MSCS
08/04/2025
Episode 414: Finding Peace in the Midst of Uncertainty with Andrea Arzt, LCSW, MSCS
Living with MS has always meant living with uncertainty. Left unchecked, that uncertainty can lead to anxiety, which can make your MS symptoms feel worse. This week, Licensed Clinical Social Worker, Andrea Arzt, joins me to share tips and strategies for finding peace in the midst of uncertainty. You'll also meet the CEO of the MS International Federation, Dr. Lydia Makaroff. And you'll hear how artist Gordon Keith is combining his art with philanthropy in support of MS Canada. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Finding peace during uncertain times :22 Dr. Lydia Makaroff discusses the work that the MS International Federation is involved in on behalf of the global MS community :58 Gordon Keith discusses his life as an artist and how he's using his art to raise funds for MS Canada 10:43 Licensed Clinical Social Worker, Andrea Arzt, offers strategies for finding peace of mind while facing uncertainty 21:40 Share this episode 32:12 Next Week: It's all about the money! 32:32 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at Become an MS Activist Join the RealTalk MS Facebook Group Download the RealTalk MS App for iOS Devices Download the RealTalk MS App for Android Devices Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 414 Guests: Dr. Lydia Makaroff, Gordon Keith, and Andrea Arzt
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Episode 413: How AI Will Impact MS Patient Care with Dr. Brad Willingham
07/28/2025
Episode 413: How AI Will Impact MS Patient Care with Dr. Brad Willingham
We're witnessing the early stages of a paradigm shift, as artificial intelligence is beginning to impact virtually every aspect of healthcare, from research to patient care. And there's much, much more to come. This week, Dr. Brad Willingham, the Director of MS Research at Shepherd Center in Atlanta, joins me to discuss how AI will impact MS patient care. We'll also share the encouraging results from a Phase 2 open-label extension study for Fenebrutinib, an investigational disease-modifying therapy. We'll tell you about study results that show exercise interventions that follow physical activity guidelines for MS can have a significant impact on MS-related depression. And we're sharing the results of a study that illustrate what can happen when you delay starting a disease-modifying therapy. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: How AI will impact MS patient care :22 Fenebrutinib shows positive results after one-year extension study 1:33 MS-related depression can be significantly eased through exercise intervention that follows physical activity guidelines for MS 3:36 What happens when you delay starting disease-modifying therapy? 8:46 Dr. Brad Willingham discusses how artificial intelligence is impacting all aspects of healthcare 14:29 Share this episode 33:18 Have you downloaded the free RealTalk MS app? 33:38 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: Phone: (310) 526-2283 And don't forget to join us in the ! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the or at Become an MS Activist STUDY: Safety and Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (FENopta): A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase 2 Trial and Open-Label Extension STUDY: Effects of Meeting Exercise Guidelines on Depression and Anxiety in Multiple Sclerosis: A Systematic Review and Meta-Analysis Exercise and Physical Activity Recommendations for ALL People with MS STUDY: Delayed Access and Adherence are Real-World Challenges That Compromise Effectiveness of Natalizumab in Multiple Sclerosis Join the RealTalk MS Facebook Group Download the RealTalk MS App for iOS Devices Download the RealTalk MS App for Android Devices Give RealTalk MS a rating and review Follow RealTalk MS on Twitter, , and subscribe to our newsletter at our website, . RealTalk MS Episode 413 Guest: Dr. Brad Willingham
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