Neuro-Oncology: The Podcast

Neuro-Oncology: The Podcast will keep you up to date about the latest advances in the field as we present conversations with the authors of selected papers from Neuro-Oncology and its sister journals, Neuro-Oncology Practice and Neuro-Oncology Advances.

Radiotherapy induced neurocognitive decline 10/24/2025

Radiotherapy induced neurocognitive decline Description: Dr. Iyad Alnahhas interviews Dr. Charlotte Sleurs about her and her team's recent manuscript entitled: "Radiotherapy-induced neurocognitive decline among adult intracranial tumor patients: A voxel-based approach", published online in Neuro-Oncology in May 2025. /episode/index/show/soc-neuro-onc/id/38615165

QOL and cognitive functioning in patients with oligodendroglioma 09/26/2025

QOL and cognitive functioning in patients with oligodendroglioma Dr. Iyad Alnahhas interviews Drs. Florien Boele and Martin Klein about their recent manuscript entitled: “Health-related quality of life and cognitive functioning in survivors of oligodendroglioma: An international cross-sectional investigation”, published online in Neuro-Oncology in July 2025. /episode/index/show/soc-neuro-onc/id/38388635

Post-operative radiation in recurrent grade 1 meningiomas 09/12/2025

Post-operative radiation in recurrent grade 1 meningiomas Dr. Iyad Alnahhas interviews Drs. Felix Sahm and Maximilian Deng about their recent manuscript entitled: "Postoperative radiotherapy in subtotally-resected recurrent WHO grade 1 meningiomas with intermediate/ high-risk molecular profiles", published online in Neuro-Oncology in May 2025. /episode/index/show/soc-neuro-onc/id/37991540

mRNA CAR T against GD2 in high-grade glioma models 08/29/2025

mRNA CAR T against GD2 in high-grade glioma models Dr. Maya Graham interviews Dr. Jessica Foster about her and her team's recent manuscript, entitled "Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high-grade glioma models". This work was published online in Neuro-Oncology in May 2025. /episode/index/show/soc-neuro-onc/id/37989630

A transcriptomic atlas of CNS tumors 07/11/2025

A transcriptomic atlas of CNS tumors Dr. Evan Noch interviews Dr. Akshitkumar Mistry about his and his team's recent manuscript entitled "A clinically annotated transcriptomic atlas of nervous system tumors", published online in Neuro-Oncology in May 2025 Link to the paper: /episode/index/show/soc-neuro-onc/id/37378755

Gut microbiome in primary CNS lymphoma 06/27/2025

Gut microbiome in primary CNS lymphoma Dr. Iyad Alnahhas interviews Drs. Isaias Hernandez-Verdin and Agusti Alentorn about their recent manuscript entitled: "Gut microbiome modulates the outcome in primary central nervous system lymphoma patients undergoing chemotherapy: An ancillary study from the BLOCAGE trial", published online in Neuro-Oncology in March 2025 Link: /episode/index/show/soc-neuro-onc/id/37155590

Germline analysis of diffuse midline glioma 06/08/2025

Germline analysis of diffuse midline glioma Dr. Evan Noch interviews Dr. Marion Mateos about her and her team's recent manuscript entitled: "Germline analysis of an international cohort of pediatric diffuse midline glioma patients", published online in Neuro-Oncology in March 2025. /episode/index/show/soc-neuro-onc/id/36842805

The proteomic landscape of diffuse midline glioma 05/17/2025

The proteomic landscape of diffuse midline glioma Dr. Iyad Alnahhas interviews Drs. Cynthia Hawkins and Arun Vadivel about their recent manuscript entitled: "The proteomic landscape of diffuse midline glioma highlights the therapeutic potential of non-histone protein methyltransferases", published online in Neuro-Oncology in February 2025. /episode/index/show/soc-neuro-onc/id/36566525

Radio-Pathomic maps and MR perfusion 04/18/2025

Radio-Pathomic maps and MR perfusion Dr. Iyad Alnahhas interviews Dr. Peter LaViolette about his and his team's recent manuscript entitled: "Multi-Site Retrospective Analysis of Diffusion and Perfusion MRI Correlates to Glioma Characteristics Derived from Radio-Pathomic Maps", published online in Neuro-Oncology in February 2025. /episode/index/show/soc-neuro-onc/id/36061325

CSF proteomics in glioma 03/21/2025

CSF proteomics in glioma Description: Dr. Evan Noch interviews Drs. Cecile Riviere-Cazaux and Terry Burns about their recent manuscript entitled: "A field resource for the glioma cerebrospinal fluid proteome: impacts of resection and location on biomarker discovery", published online in Neuro-Oncology in December 2024. Link: /episode/index/show/soc-neuro-onc/id/35814780

Vorasidenib in IDH mutant glioma 03/08/2025

Vorasidenib in IDH mutant glioma Description: Dr. Ankush Bhatia interviews Drs. Macarena de la Fuente and Mehdi Touat about their recent manuscript entitled: "The role of vorasidenib in the treatment of isocitrate dehydrogenase-mutant glioma" published online in Neuro-Oncology in December 2024. Link: /episode/index/show/soc-neuro-onc/id/35539975

KL-50 in post TMZ MMR-deficient GBM 02/22/2025

KL-50 in post TMZ MMR-deficient GBM Dr. Iyad Alnahhas interviews Dr. Craig Horbinski about his and his team's recent manuscript entitled "The novel DNA cross-linking agent KL-50 is active against patient-derived models of new and recurrent post-temozolomide mismatch repair-deficient glioblastoma", published online in Neuro-Oncology in December 2024. /episode/index/show/soc-neuro-onc/id/35279225

Measurable disease per FET-PET vs MRI in GBM 02/08/2025

Measurable disease per FET-PET vs MRI in GBM Dr. Iyad Alnahhas interviews Dr. Nathalie Albert about her and her team's recent manuscript entitled: "Measurable disease as baseline criterion for response in glioblastoma: A comparison of PET-based (PET RANO 1.0) and MRI-based (RANO) assessments", published online in Neuro-Oncology in January 2025. /episode/index/show/soc-neuro-onc/id/35060585

Pre-radiation chemotherapy in GBM 01/20/2025

Pre-radiation chemotherapy in GBM Dr. Iyad Alnahhas interviews Dr. Danielle Bazer about her and her team's recently published manuscript, entitled: Using a Pre-Radiation Window to Identify Potentially Active Cytotoxic Agents in Adults with Newly Diagnosed Glioblastoma", published online in Neuro-Oncology in November 2024. /episode/index/show/soc-neuro-onc/id/34858740

cIMPACT-NOW Update 8: grading of meningiomas 12/13/2024

cIMPACT-NOW Update 8: grading of meningiomas Dr. Rachna Malani interviews Drs. Felix Sahm and Arie Perry about their recent manuscript entitled: "cIMPACT-NOW Update 8: Clarifications on molecular risk parameters and recommendations for WHO grading of meningiomas", published online in Neuro-Oncology in August 2024 /episode/index/show/soc-neuro-onc/id/34389865

Residual tumor volume and survival after CCNU/TMZ in GBM 11/24/2024

Residual tumor volume and survival after CCNU/TMZ in GBM Dr. Iyad Alnahhas interviews Drs. Thomas Zeyen and Johannes Weller about their recent manuscript entitled: "Quantitative assessment of residual tumor is a strong and independent predictor of survival in methylated glioblastoma following radiochemotherapy with CCNU/TMZ", published online in Neuro-Oncology in October 2024. /episode/index/show/soc-neuro-onc/id/33812887

Alterations in RNA splicing between meningioma DNA methylation groups 11/08/2024

Alterations in RNA splicing between meningioma DNA methylation groups Dr. Evan Noch interviews Drs. Nathan Leclair, David Raleigh and Olga Anczukow about their recent manuscript entitled: "RNA splicing as a biomarker and phenotypic driver of meningioma DNA methylation groups", published online in Neuro-Oncology in August 2024. /episode/index/show/soc-neuro-onc/id/33812477

The immune landscape of IDH mutant and IDHwt glioma 10/25/2024

The immune landscape of IDH mutant and IDHwt glioma Dr. Evan Noch interviews Drs. Pravesh Gupta and Krishna Bhat about their recent manuscript entitled "Immune landscape of isocitrate dehydrogenase-stratified primary and recurrent human gliomas", published online in Neuro-Oncology in August 2024 /episode/index/show/soc-neuro-onc/id/33591527

Equity-driven applications of AI in neuro-oncology 10/09/2024

Equity-driven applications of AI in neuro-oncology Dr. Iyad Alnahhas interviews Dr. Mulki Mehari about her and her team's recent manuscript entitled: "Enhancing neuro-oncology care through equity-driven applications of artificial intelligence", published online in Neuro-Oncology in August 2024. /episode/index/show/soc-neuro-onc/id/33233352

IDH mutant glioma across age groups 09/20/2024

IDH mutant glioma across age groups Dr. Maya Graham interviews Drs. Mary Jane Lim-Fat and Kee Kiat Yeo about their recent manuscript entitled "A comparative analysis of IDH-mutant glioma in pediatric, young adult, and older adult patients", published online in Neuro-Oncology in July 2024. Link: /episode/index/show/soc-neuro-onc/id/33139202

Contemporary molecular prognostic signatures in glioma 08/30/2024

Contemporary molecular prognostic signatures in glioma Dr. Iyad Alnahhas interviews Dr. Linda Bi, Hia Ghosh and Ruchit Patel about their recent manuscript entitled: "Contemporary Prognostic Signatures and Refined Risk Stratification of Gliomas: An Analysis of 4400 Tumors", published online in Neuro-Oncology in August 2024. More Information: /episode/index/show/soc-neuro-onc/id/32770552

FDG PET in PCNSL 08/09/2024

FDG PET in PCNSL Dr. Iyad Alnahhas interviews Drs. Minyoung Oh and Hyungwoo Cho about their recent manuscript entitled: "Enhancing Prognostication and Treatment Response Evaluation in Primary CNS Lymphoma with 18F-FDG PET/CT", published online in Neuro-Oncology in August 2024. /episode/index/show/soc-neuro-onc/id/32508702

TMZ and MGMT in elderly GBM patients 07/12/2024

TMZ and MGMT in elderly GBM patients Dr. Jasmin Jo interviews Dr. Monika Hegi about her and her team's recent manuscript entitled: "No benefit from TMZ treatment in GB with truly unmethylated MGMT promoter: Reanalysis of the CE.6 and the pooled Nordic/NOA-08 trials in elderly GB patients", published online in Neuro-Oncology in (I will fill in through Libsyn) /episode/index/show/soc-neuro-onc/id/32115097

IDH mutant glioma and IDH inhibitors 07/05/2024

IDH mutant glioma and IDH inhibitors Dr. Maya Graham interviews Dr. Martin van den Bent about his and his team's recent review article entitled "The biological significance of age, enhancement, extent of resection and tumor grade in IDH mutant gliomas: how should they inform treatment decision in the era of IDH inhibitors? Invited review", published online in Neuro-Oncology in /episode/index/show/soc-neuro-onc/id/32019057

Leptomeningeal disease, a SNO and ASCO review 06/28/2024

Leptomeningeal disease, a SNO and ASCO review Dr. John Fortunato interviews Dr. Adrienne Boirre about her and her team's recent manuscript entitled "Leptomeningeal metastases from solid tumors: A SNO and ASCO consensus review on clinical management and future directions", published online in Neuro-Oncology on /episode/index/show/soc-neuro-onc/id/31919567

Cancer stems cell in GBM 06/21/2024

Cancer stems cell in GBM Dr. Iyad Alnahhas interviews Drs. Justin Lathia and Marco Gallo about their recent manuscript entitled "Cancer stem cell hypothesis 2.0 in glioblastoma: where are we now and where are we going?", published online in Neuro-Oncology in May 2024. /episode/index/show/soc-neuro-onc/id/31851427

Drug delivery across the blood-brain barrier 06/13/2024

Drug delivery across the blood-brain barrier Dr. Ankush Bhatia interviews Dr. Keaton Piper about his and his team's manuscript, entitled "Consensus Review on Strategies to Improve Delivery Across the BBB Including Focused Ultrasound", published online in Neuro-Oncology in May 2024 /episode/index/show/soc-neuro-onc/id/31725177

Gliomatosis cerebri in children 05/24/2024

Gliomatosis cerebri in children Dr. Evan Noch interviews Dr. Gunther Nussbaumer about his recent paper entitled: "Gliomatosis cerebri in children: a poor prognostic phenotype of diffuse gliomas with a distinct molecular profile" published online in Neuro-Oncology in May 2024. /episode/index/show/soc-neuro-onc/id/31345682

Immunotherapy drives mesenchymal shift in GBM 05/17/2024

Immunotherapy drives mesenchymal shift in GBM Dr. Maya Graham interviews Drs. Josephine Hendriksen and Joachim Weischenfeldt about their recent manuscript, "Immunotherapy drives mesenchymal tumour cell state shift and TME immune response in glioblastoma patients," published online in Neuro-Oncology in May 2024. /episode/index/show/soc-neuro-onc/id/31345422

Long-term outcomes of pediatric patients with optic pathway glioma 05/04/2024

Long-term outcomes of pediatric patients with optic pathway glioma Dr. Iyad Alnahhas interviews Drs. Alice Morin, Samuel Abbou and Brice Fresneau about their recent manuscript entitled "Very long-term outcomes of pediatric patients treated for optic pathway gliomas: a longitudinal cohort study" published online in Neuro-Oncology in March 2024. /episode/index/show/soc-neuro-onc/id/31113098

Neuro-Oncology: The Podcast

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