TopMedTalk
TopMedTalk for the latest medical news surrounding Anaesthesia, Perioperative Care and Enhanced Recovery. Live updates from conferences; Journal Club; Techno Talk and Hot-Topic podcasts. Continuing Medical Education (CME) on the go
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Perioperative Pain Management; opioid reduction service
06/30/2025
Perioperative Pain Management; opioid reduction service
In this piece we look at the opioid crisis in the UK and how it has translated into clinical practice. Hear about the history and data behind opioid prescription trends, specifically highlighting the high-risk patient demographics and mortality figures associated with opioid use. Learn how a multidisciplinary approach, taken by the opioid reduction service at Guy’s & St. Thomas', helps showcase early outcome data and the strategies employed in opioid weaning. Emphasizing the importance of patient engagement and personalized care we detail the clinic’s processes, preparations, and long-term strategies for opioid tapering. The episode concludes with a compelling patient testimonial video reflecting the positive outcomes of the service. Fauzia Hasnie, Consultant Lead, Opioid Multidisciplinary Pain Management Clinic, Joint Lead, Combined Sickle-Opioid Virtual Multidisciplinary Clinic Guy’s & St Thomas’ NHS Foundation Trust. Resources: UK National Institute for Health Care Excellence (NICE) guidelines: US Centers for Disease Control and Prevention (CDC):
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Perioperative Pain Management; Opioid Sparing Analgesia strategies guided by NOL index
06/23/2025
Perioperative Pain Management; Opioid Sparing Analgesia strategies guided by NOL index
This piece focuses on strategies for opioid-sparing anesthesia guided by the NOL Index, emphasizing the variability in patient responses to opioids. The importance of monitoring nociception, using advanced devices and techniques to customize opioid dosing, reduce side effects, and confirm the effectiveness of regional anesthesia. Our presenter shares personal experiences from their professional life and case studies, illustrating the benefits and challenges of implementing multimodal and opioid-free anesthesia approaches. The talk highlights the need for individualized treatment strategies in critical care and anesthesia. Presented by Esteban Salas Rezola, Specialist in Anaesthesiology, Resuscitation and Pain Therapy at Hospital General Alicante.
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Diversity at Euroanaesthesia 2025
06/16/2025
Diversity at Euroanaesthesia 2025
Euroanaesthesia 2025: the annual meeting of the European Society of Anaesthesiology and Intensive Care, in Lisbon, Portugal. TopMedTalk were there, check out our coverage on our podcast timeline. We’ve released many bonus episodes over the last few weeks! In this piece Kate Leslie and Nick Margerrison speak with their guests Sarah Saxena, course director and professor of anaesthesiology at the University of Mons, Belgium and Mia Gisselbaek, an anaesthesiologist and PhD student in medical education at University of Geneva Hospital, Switzerland. Drs Saxena and Gisselbaek were members of the working group for the ESAIC Mellin-Olsen Declaration on Diversity, Equity and Inclusion, which was signed at the opening ceremony of Euroanaesthesia 2025 in Lisbon, Portugal. The declaration can be found here: . doi: 10.1097/EJA.0000000000002186 A link to the machine learning algorithm for delirium developed by Drs Saxena and Gisselbaek can be found here
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Insights from the WFSA with Wayne Morriss
06/09/2025
Insights from the WFSA with Wayne Morriss
This piece was recorded at Euroanaesthesia 2025 in Lisbon. Kate Leslie interviews Wayne Morriss, Clinical Associate Professor, University of Otago, Christchurch, and Specialist Anaesthetist, Christchurch Hospital, New Zealand. He is the Immediate Past President of the World Federation of Societies of Anaesthesiologists (WFSA). He shares his insights from his journey in global anaesthesia, including his tenure as WFSA president. We discuss global issues in anaesthesiology, the importance of international aid and education, and the development of the Essential Pain Management program. Wayne also reflects on influential figures such as the late Dr. Jannicke Mellin-Olsen and the WFSA's ongoing initiatives under its current leader, Prof Daniela Filipescu.
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The mission and vision at Euroanaesthesia 2025
06/02/2025
The mission and vision at Euroanaesthesia 2025
We're at Euroanaesthesia 2025 in Lisbon, Portugal. Here we discuss the European Society of Anaesthesiology and Intensive Care's initiatives, focusing on the innovations in the scientific program in anaesthesia and perioperative medicine, and the importance of inclusivity and diversity within the society. The episode also highlights the future direction of the society, the role of trainees, and offers insights into the upcoming Congress in Rotterdam. Listeners are encouraged to apply for roles and join the society for its educational resources and global networking opportunities. Presented by Kate Leslie with her guests, Michel Struys is Professor and Chair, Department of Anesthesiology, University of Groningen and University Medical Center Groningen, the Netherlands, and chair of the Scientific Committee of ESAIC, and Fabio Guarracino, Head of the Department of Cardiothoracic Anaesthesia and Intensive Care at Pisa University Hospital, Pisa, Italy, and incoming chair of the Scientific Committee of ESAIC.
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Patient Safety, Sustainability, and AI in Anaesthesiology
05/31/2025
Patient Safety, Sustainability, and AI in Anaesthesiology
Recorded at Euroanesthesia 2025 in Lisbon, Portugal, the annual meeting of the European Society of Anesthesiology and Intensive Care. The episode features an interview with Edoardo de Roberti, a former ESAIC president, who shares insights into the challenges and advancements in the field of anesthesiology. Key topics include patient safety, sustainability in medical practices, and the role of artificial intelligence in improving anesthesiology. Eduardo also discusses workforce shortages in Europe and the importance of maintaining a well-trained and happy workforce for optimal patient outcomes. Presented by Kate Leslie, with her guest Edoardo De Robertis, Professor and Director of Anaesthesiology and Intensive Care, Università degli Studi di Perugia, Italy, and former president of ESAIC. He currently serves on the National Anaesthesiologists Societies Committee (NASC).
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Advancing Patient Safety in Anaesthesiology
05/31/2025
Advancing Patient Safety in Anaesthesiology
Recorded at the Euroanaesthesia 2025 meeting in Lisbon, Portugal. Here the focus is on patient safety in anaesthesiology. We discuss the importance of patient safety preoperatively, intraoperatively, and postoperatively, with innovations in perioperative medicine and artificial intelligence. The ESAIC Patient Safety and Quality Committee developed a patient safety education project: the Safer Care to Save Lives, a comprehensive package of patient safety education for anaesthesiologists, healthcare professionals, hospital management and patients. We also look at the need for standardized protocols, effective communication, and remote monitoring to enhance postoperative patient care. The episode concludes with a call to action for practitioners to engage in patient safety training and a look forward to the next congress in Rotterdam. Presented by Kate Leslie, with her guest, Benedikt Preckel, Professor of Anaesthesiology, Patient Safety in the Perioperative Period and Quality of Care, University of Amsterdam Medical Center, in the Netherlands, and Chair of the ESAIC Patient Safety and Quality Committee.
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Innovations in Monitoring Right Heart Failure with the Swan IQ Catheter
05/31/2025
Innovations in Monitoring Right Heart Failure with the Swan IQ Catheter
In this piece we discuss the intricacies of right heart failure, the differences between the right and left ventricles, and the challenges of early detection and monitoring. With a focus upon research we discuss the Swan-Ganz IQ pulmonary artery catheter, with the FastCCO algorithm, from BD Advanced Patient Monitoring. We cover its innovative capabilities, explore its impact on patient care and look particularly at high-risk patients like those with pulmonary hypertension and LVADs. The episode highlights the importance of new monitoring techniques, future research directions, and the promise of continuous data in improving right ventricular function diagnosis and treatment. Presented by Kate Leslie with her guest Joerg Ender, Director of the Department for Anesthesiology and Intensive Care Medicine, Heart Center, Leipzig, Germany. He is second president of the German Society of Anesthesiology and Intensive Care Medicine and former Secretary General of the European Association of Cardiothoracic Anaesthesiologists (EACTA).
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Exploring Cerebral Autoregulation
05/29/2025
Exploring Cerebral Autoregulation
Our guest, Chiara Robba, delves into her work on cerebral autoregulation in relation to critical illness. We explore the mechanisms of cerebral autoregulation in healthy and brain-injured patients, the potential of new monitoring technologies, and the importance of personalized patient care. The discussion also touches on the broader implications for managing blood pressure in various clinical scenarios, including sepsis and shoulder surgery. Presented by Kate Leslie and Monty Mythen with their guest, Chiara Robba who is Professor of Anaesthesia and Intensive Care, IRCSS Policlinico San Martino, Genova, Italy; and Past Chair of the Neurointensive Care Section of European Society of Intensive Care Medicine.
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Evolution of the European Society of Anaesthesiology and Intensive Care
05/29/2025
Evolution of the European Society of Anaesthesiology and Intensive Care
Euroanaesthesia 2025 in Lisbon, Portugal. Here we look at the history and progress of the European Society of Anaesthesiology and Intensive Care. We speak about the amalgamation of three separate societies into one, the inclusion of intensive care, key milestones like the Helsinki, Glasgow and Mellon-Olsen Declarations, and the significance of involving trainees. We also highlight the Society’s efforts in promoting research and its relationship with the European Journal of Anaesthesiology. More here: Presented by Kate Leslie with her guest, Stefan De Hert, emeritus professor of anesthesiology, University of Ghent, Belgium, and past president of ESAIC. He served on all major committees of the Society and is ideally placed to talk us through the achievements of the last 20 years.
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Introduction to Euroanaesthesia 2025
05/26/2025
Introduction to Euroanaesthesia 2025
The TopMedTalk team takes you to Euroanaesthesia 2025: The European Society of Anaesthesiology and Intensive Care annual meeting in Lisbon, Portugal. The Society is dedicated to supporting professionals in anaesthesiology and intensive care by serving as the hub for development and dissemination of valuable educational, scientific, research, and networking resources. This year we're bringing you interviews with some of the key players and speakers from the conference presented by our very own Professor Kate Leslie, Head of Research in the Department of Anaesthesia and Pain Management at Royal Melbourne Hospital.
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TopMedTalks to Manu Malbrain; the patient experience
05/19/2025
TopMedTalks to Manu Malbrain; the patient experience
This piece follows on from the previous interview with Manu Malbrian, but works as a standalone podcast. It is presented from the annual conference of the Society of Critical Care Medicine (SCCM), the largest non-profit medical organization dedicated to promoting excellence and consistency in the practice of critical care. Here our guest very kindly shares his personal experience of critical care, before the conversation moves into the patient experience in general. Presented by Desiree Chappell and Monty Mythen with their guest Manu Malbrain, CMO of Medaman, an initiative that seeks to optimize the use of data in hospitals, combined with a position as professor of Critical Care Research at the First Department of Anesthesiology and Intensive Therapy of the Medical University of Lublin in Poland. He is a co-founder and president of the International Fluid Academy (IFAD), the co-founder, past president, and current treasurer of the Abdominal Compartment Society (WSACS), author and co-author of more than 386 peer-reviewed articles, reviews, comments, editorials, book chapters, and books on abdominal compartment syndrome (ACS) and rational fluid use. His cumulative h-index is 63 on Scopus and 85 on GoogleScholar (with a total of 37000 citations). We mention - and recommend it again here. You can find him here: The previous podcast, from which this piece follows on, is here:
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Revolutionizing Anesthesia: The Jaw Elevation Device (JED) - A Deep Dive with Inventor April King
05/12/2025
Revolutionizing Anesthesia: The Jaw Elevation Device (JED) - A Deep Dive with Inventor April King
This piece focuses upon an innovative device that has transformed patient care in Anesthesia; the Jaw Elevation Device (JED), a non-invasive tool designed to keep patients' airways open during moderate anesthesia care (MAC). The conversation explores the challenges of MAC, the device's adaptability across different patient demographics, and its impact on improving patient safety and practitioner efficiency. Learn more about the evolution of JED, its clinical applications, and where to find this groundbreaking device. Presented by Desiree Chappell with April King, Co-Founder, Director, President and CEO of Hypnoz Therapeutic Devices, creator of the JED and Irene Osborn, Director, Non-Operating Room Anesthesia and Professor, Anesthesiology at Montefiore
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Review of the 2025 ANZCA Annual Scientific Meeting in Cairns
05/06/2025
Review of the 2025 ANZCA Annual Scientific Meeting in Cairns
In this piece, we recap the last five days at the ANZCA Annual Scientific Meeting. We visit highlights from the plenary speaker presentations by Chris Connor, Alana Flexman, Ramani Moonesinghe, Kevin Fong and Eugenie Kayak. We talk about the original research presented at the meeting including the breaking trials session. Then we review the great discussions we had with journal editors at the meeting. Finally we reflect on the great social events at the meeting, that foster fellowship and collegiality among anaesthetists. Go to our app or website to hear great podcasts recorded during the meeting. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia.
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Breaking trial results
05/06/2025
Breaking trial results
In this piece we discuss breaking trial results with Chris Bain, a consultant anaesthetist and researcher, and Luke Perry, a trainee anaesthetist and PhD student*, both from Melbourne, Australia. We explore the effects of tissue trauma on inflammation and immune responses, and new results about the modifying effect of genetic expression with glucocorticoids. Then we delve into a pilot study on pulmonary artery catheters and cardiac surgery: one of the big questions in our specialty. The pilot study showed that a large randomised trial is feasible and has equipoise. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guests, Dr Chris Bain, Department of Anaesthesia and Perioperative Medicine, The Alfred Hospital and Monash University, Melbourne, Australia and Dr Luke Perry, an ANZCA trainee in Melbourne, a PhD student at the University of Melbourne, and Head of Research, Victorian Heart Hospital, Melbourne, Australia.
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Journals in focus, The BJA and Anesthesiology
05/05/2025
Journals in focus, The BJA and Anesthesiology
In this piece we discuss the latest news in medical publishing with Hugh Hemmings, editor-in-chief of the British Journal of Anaesthesia and Laszlo Vutskits, editor of Anesthesiology. We discuss the increasing volume of manuscripts being received by journals; the challenges of peer review, and initiatives to find and support new reviewers. Then we delve into the use of AI by authors and journals, and how this might influence publishing in the future. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guests, Dr Hugh Hemmings, Joseph F. Artusio Jr. Professor and Chair, Department of Anesthesiology, Weill-Cornell Medicine, New York, USA, and Dr Laszlo Vutskits, Head of Pediatric Anesthesia at the Department of Anesthesiology, Pharmacology and Intensive Care at the University Hospital of Geneva, Switzerland.
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Unconscious bias, bullying, harassment, and discrimination
05/05/2025
Unconscious bias, bullying, harassment, and discrimination
In this piece we discuss perioperative medicine with Alana Flexman, an anaesthetist and researcher from Vancouver, Canada, and Maryanne Balkin, an anaesthetist and law graduate from Melbourne, Australia. We explore our guests’ career journeys, and gender and equity issues, including unconscious bias and bullying, harassment, and discrimination, in the workplace. Finally we talk about the craziness and joy of continued learning and enquiry. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guests, Dr Alana Flexman, Clinical Associate Professor, Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, and St. Paul’s Hospital/Providence Health Care, Vancouver, Canada, and Dr Maryanne Balkin, Consultant Anaesthetist, Alfred Health, Melbourne, Australia.
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TopMedTalks to … Kevin Fong
05/04/2025
TopMedTalks to … Kevin Fong
In this piece we discuss risk in medicine with Kevin Fong, a consultant anaesthetist, retrieval medicine specialist, and broadcaster. In a wide-ranging conversation we talk about risk in anaesthesia, the effect of adverse events on individual practitioners and teams, and workforce issues in health. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with Professor Kevin Fong, Consultant Anaesthetist and Anaesthetic Lead for Major Incident Preparedness, University College London Hospitals, and Professor of Engagement and Innovation for Science and Medicine at University College London.
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Understanding the processed EEG in anaesthesia
05/04/2025
Understanding the processed EEG in anaesthesia
In this piece we discuss all things EEG with Chris Connor, an anesthesiologist and researcher from Boston, USA, and Jamie Sleigh, an anesthesiologist and researcher from Hamilton, New Zealand. We start by discussing the engineering behind the BIS algorithm, then move to interpreting the raw EEG, the spectrogram and burst suppression. Finally we discuss the ‘titration paradox’ and how it might influence research and AI. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guests, Dr Chris Connor, Assistant Professor and Vice Chair ad interim for Research, Brigham and Women’s Hospital, Boston, USA, and Professor Jamie Sleigh, Professor of Anaesthesiology and Intensive Care, Waikato Clinical School, University of Auckland, New Zealand.
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Haemorrhage associated with trauma and major surgery
05/04/2025
Haemorrhage associated with trauma and major surgery
In this piece we discuss blood management in emergency and elective surgery with Matthew Wiles, an anaesthetist from Sheffield, UK, and editor of the journal Anaesthesia, and Catherine Downs, an anaesthetist from Sydney, Australia. The episode delves into haemorrhage associated with trauma and major surgery, and the benefits of point of care testing. We also took the opportunity to discuss authorship of scholarly work and the need to support emerging researchers and site collaborators. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guests, Dr Matthew Wiles, Consultant Anaesthetist and Clinical Lead for Major Trauma, Sheffield Hospitals NHS Foundation Trust, and Honorary Senior Clinical Lecturer, Sheffield University, Sheffield, UK, and Dr Catherine Downs, Consultant Anaesthetist, Prince of Wales Hospital, and Senior Lecturer, Randwick Clinical Campus, University of New South Wales, Sydney, Australia
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Improving sustainability and reducing operating room waste
05/04/2025
Improving sustainability and reducing operating room waste
In this piece we discuss sustainability in healthcare with Eugenie Kayak, an anaesthetist from Melbourne, Australia, and Dan Lazzari, an anaesthetist from Cairns, Australia. The episode delves into Eugenie’s journey with Doctors for the Environment Australia and her work as an educator in sustainability. We discuss national and international solutions, and local initiatives by Dan and his colleagues to improve sustainability and reduce operating room waste in Cairns. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guests, Professor Eugenie Kayak, Enterprise Professor in Sustainable Healthcare, University of Melbourne, and Dr Daniele Lazzari, Consultant Anaesthetist, Cairns Hospital, Australia.
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Perioperative medicine, the challenges, the rewards and the future
05/03/2025
Perioperative medicine, the challenges, the rewards and the future
In this piece we discuss perioperative medicine with Ramani Moonesinghe, an anaesthetist and intensive care specialist from London, England, and Phuong Markman, an anaesthetist from Cairns, Australia. We explore access to and outcomes from surgery, particularly in relation to remoteness and socioeconomic deprivation. Then we talk about specific interventions to improve the patient experience, such as Sip til Send, and the challenges of implementing the program and demonstrating that it’s safe with respect to aspiration. Finally we discuss whether AI and robotics can assist patients in the perioperative journey. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guests, Professor Ramani Moonesinghe, Professor of Perioperative Medicine, University College London, National Director of Patient Safety and National Clinical Director for Critical and Perioperative Care, NHS England, and Dr Phuong Markman, Consultant Anaesthetist, Cairns Hospital, Australia.
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Management of neuropathic and paediatric pain
05/03/2025
Management of neuropathic and paediatric pain
In this piece we discuss pain medicine with Nadine Attal, a neurologist and pain medicine specialist from France, and Allen Finley, an anesthesiologist and pain medicine specialist from Canada. The episode delves into neuropathic pain and the need to personalize its management, and efforts to standardize the management of paediatric pain in Canada. We talk about the ICD-11 which recognizes chronic pain as a disease, and ChildKind.org which nurtures holistic and responsive support for children or all ages and abilities. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guests, Professor Nadine Attal, Director for the Center of Evaluation and Treatment of Pain, Ambroise Paré Hospital, Paris, France, and Professor Allen Finley, Professor of Anesthesia and Psychology at Dalhousie University, and Medical Director of Pediatric Pain Management at IWK Health Centre in Halifax.
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Studying hypothermia and the value of trainee research
05/03/2025
Studying hypothermia and the value of trainee research
In this piece we discuss prevention of intraoperative hypothermia with Holly Tonkin, a trainee anaesthetist from Australia. Holly describes her study, in which she measured the prevalence of hypothermia using routine forced air warming and then the prevalence using the 3M™ Bair Hugger™ Universal Warming Gown. Significant reductions in hypothermia were observed. Holly’s study was supported by Solventum. We then discussed the value of trainee research. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guest, Dr Holly Tonkin, Manning Base Hospital and Royal North Shore Hospital, New South Wales, Australia.
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Future Proofing Emerging Leaders in Anaesthesia
05/03/2025
Future Proofing Emerging Leaders in Anaesthesia
In this piece we discuss hot topics in anaesthesia and pain medicine with David Story, President of the Australian and New Zealand College of Anaesthetists and Dilip Kapur, Dean of the Faculty of Pain Medicine. The episode delves into the exciting presentations and events at the meeting, and discusses ‘Future proofing’ through developing emerging leaders, supporting research and advocating for sustainability in healthcare in Australia and New Zealand. Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia, with their guests, Professor David Story, Chair, Department of Critical Care, University of Melbourne, and Dr Dilip Kapur, a pain medicine from South Australia.
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Welcome to our coverage of the 2025 ANZCA Annual Scientific Meeting (ASM)
05/03/2025
Welcome to our coverage of the 2025 ANZCA Annual Scientific Meeting (ASM)
In this piece, Andy Cumpstey and Kate Leslie introduce listeners to the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine, being held in Cairns, in beautiful Far North Queensland, Australia. They discuss the history of the meeting, the role of the College and Faculty in CPD for specialists and the wonderful events coming up at the conference. Also, hear about how to tell a ‘freshy’ from a ‘salty’ (crocodile, that is)! Presented by Andy Cumpstey and Kate Leslie on location at the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine in Cairns, Australia.
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Review of the 2025 IARS conference | IARS
04/28/2025
Review of the 2025 IARS conference | IARS
Recorded at the close of the recent IARS (International Anesthesia Research Society) annual meeting held in Honolulu, Hawaii. Our co-editor in Chief Professor Mike Grocott’s arrival at the IARS from the UK was delayed by a fire at Heathrow airport. This piece turns his late arrival into your good fortune, as both Professor Kate Leslie and Professor Monty Mythen, TopMedTalk’s founder, fill him in on the conference. If you missed the IARS this year or were there but could do with a high level summary of the highlights, this podcast is a great place to start. The discussions cover Monty’s workshop presentation on clinical trials and industry partnerships, reflections on clinical trials conducted outside the US, and the potential underutilization of American data in large pragmatic trials. They also talk about cutting-edge trial designs, new drug developments in anesthesia, and notable research abstracts presented at the meeting. Moreover, they cover topics like exercise prehabilitation, nutrition, and cognitive training pre-surgery. There’s an emphasis on the importance of evidence-based guidelines, the potential for combining protocolization with personalized care, and the significant role interactive physical and cognitive exercise plays in patient outcomes. The PREPARE trial piece is here: We mention the forthcoming “2025 World Congress of Prehabilitation and Perioperative Medicine - International Prehabilitation and Perioperative Exercise Testing Society” meeting. More details on that here: Also, we mention Chelsia Gillis, Assistant Professor in the School of Human Nutrition in the Faculty of Agricultural and Environmental Sciences at McGill University. She has featured multiple times on TopMedTalk, if you’d like to hear some of her work start here:
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The Cipher HPI trial with Sandy Jackson | IARS
04/21/2025
The Cipher HPI trial with Sandy Jackson | IARS
The Cipher HPI study focuses on continuous, iterative, perioperative, holistic risk evaluation using advanced hemodynamic monitoring data. The study, integrates preoperative and intraoperative data to predict the need for vasopressors or fluid after surgery. We discuss the study's methodology, results, and the potential implications for clinical practice, including the use of machine learning techniques for better risk prediction and resource optimization in critical care settings. The episode emphasizes the importance of utilizing rich patient data throughout the surgical journey to enhance outcomes and support clinician decision-making. Presented by Mike Grocott and Kate Leslie on location at the International Anesthesia Research Society (IARS) and Society of Critical Care Anesthesiologists meeting in Honolulu, Hawaii, with their guest, Alexander (Sandy) Jackson an anaesthetist and intensive care physician who is also a clinican data scientist, currently funded by the UK's National Insitute of Health and Care Research (NIHR), based at the NIHR Southampton Biomedical Research Centre. We mention Guy Ludbrook, Professor of Anaesthesia at the University of Adelaide and Royal Adelaide Hospital, and an occasional presenter here on TopMedTalk. This thought provoking talk from him is a good place to learn more:
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The PREPARE trial with Daniel McIsaac | IARS
04/14/2025
The PREPARE trial with Daniel McIsaac | IARS
The PREPARE trial is a randomized control trial aimed at improving surgical outcomes for older patients with frailty through prehabilitation. This discussion covers the inspiration behind the trial, the structure of the prehabilitation program, and the trial's results. Despite not finding significant improvements in the primary outcomes across all patients, the trial revealed that those who adhered to the program showed clinically meaningful improvements. The conversation delves into the challenges of patient adherence, the role of technology, and the importance of personalized interventions in prehabilitation. Presented by Mike Grocott and Kate Leslie on location at the International Anesthesia Research Society (IARS) and Society of Critical Care Anesthesiologists meeting in Honolulu, Hawaii, with their guest, Daniel McIsaac, Associate Professor of Anesthesiology & Pain Medicine, University of Ottawa, Canada. Further resources: We mention Chelsia Gillis, Assistant Professor in the School of Human Nutrition in the Faculty of Agricultural and Environmental Sciences at McGill University. She has appeared on this podcast multiple times, this presentation is a good place to start: We also discuss The Duke Activity Status Index (DASI) can be found here: There’s also an excellent presentation on which relates to this conversation here: Ensure you are subscribed to TopMedTalk now so you can make full use of our extensive archive with over 8 years worth of high quality medical material available for free.
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Gender Disparities in Surgical Efficiency and Outcomes | IARS
04/07/2025
Gender Disparities in Surgical Efficiency and Outcomes | IARS
In this piece we discuss a ground breaking study on gender differences in surgical efficiency and outcomes with Anika Bald, a medical student from Germany, and Dr. Matthias Eikermann, a clinician scientist and department chair at Montefiore Einstein in New York. The study reveals that women surgeons have shorter delays to starting surgical add-on cases and better postoperative outcomes compared to men. The episode delves into the implications of these findings and discusses the value of diversity and inclusion in medical research and practice. Presented by Mike Grocott and Kate Leslie on location at the International Anesthesia Research Society (IARS) and Society of Critical Care Anesthesiologists meeting in Honolulu, Hawaii, with their guests, Matthias Eikermann, Professor and Chair of Anesthesiology at the Montefiore Medical Center in New York USA and Anika Bald a medical student from Germany.
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