Coffee Conversation with Steven Plymale and Milos Popovic at Toronto Rehabweek 2019
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
Release Date: 06/28/2019
Ali Samiian - The Hidden Barrier That Kills Neurotech Startups
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek speaks with , founder of , about one of the most overlooked challenges in neurotechnology and medical devices: reimbursement. Ali has spent over 20 years working across pharma, medical devices, and neuromodulation, including leadership roles at Abbott, Novartis, and Cala Health, where he helped secure reimbursement for a first-in-class wearable neuromodulation therapy for essential tremor. In this conversation, Ali explains why FDA approval alone is often not enough for a company to succeed, and why coding, coverage, and...
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Ellyn Ito - MindVibe and Non-Invasive Vagus Nerve Stimulation for Stress and Focus
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek speaks with , CEO and co-founder of , about their wearable neurotechnology platform and flagship product, MindVibe. This non-invasive device combines vagus nerve stimulation and acupressure-based neuromodulation to help regulate the body’s stress response and improve overall wellness. Ellyn shares how MindVibe is designed to promote calm, enhance focus, and improve sleep quality through ultra-low electrical stimulation that users don’t even feel. The conversation explores the science behind multi-mode stimulation, why...
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Dr. Christian Iorio-Morin - From Gamma Knife to Neuroprosthetics: The Future of Functional Neurosurgery
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek speaks with , functional neurosurgeon and professor at the , about the evolving landscape of neurosurgery—from treating movement disorders and chronic pain to pushing the boundaries of paralysis recovery. Christian shares insights from his clinical work using gamma knife surgery, neuromodulation, and microvascular techniques, as well as his leadership on the RE-MOVE project, a large-scale initiative aiming to restore movement by reconnecting the brain and spinal cord through implantable technology. The conversation...
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Omari Bouknight - Resonant Link Medical and the Next Generation of Wirelessly Powered Neurotech
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with , CEO of , to explore how advances in wireless power transfer are reshaping the future of implantable medical devices. Omari shares how traditional power limitations have historically constrained device design—and how Resonant Link Medical’s technology is turning power into an enabler, allowing for smaller, smarter, and longer-lasting implants. The conversation dives into real-world applications across neurotech and beyond, including how faster, more efficient wireless charging could unlock advanced...
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Francesco Petrini - SensArs and the Future of Sensory Neuroprosthetics for Diabetic Neuropathy
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with Francesco Petrini, co-founder and CEO of SensArs, to discuss how intraneural stimulation could help restore sensation in patients with diabetic neuropathy. Francesco explains how loss of feeling in the feet can lead to unnoticed injuries, chronic wounds, and even amputations - and why rebuilding sensory feedback could dramatically improve quality of life. The conversation explores SensArs’ approach to neuromodulation and what it takes to translate sensory neuroprosthetics into real-world clinical impact. Top...
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Ignacio Sáez - Neurotechnology for Cognition: Recording and Modulating the Human Brain
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with Dr. , , whose lab uses intracranial brain recordings to study the biology of human cognition. Ignacio shares how cutting-edge neurotechnology like iEEG can reveal the neural dynamics behind decision-making, risk, memory, and brain states - and how those insights could unlock more targeted neuromodulation therapies for psychiatric disorders such as depression and anxiety. Top 3 Takeaways: Epilepsy patients undergoing seizure monitoring often have 100-200 electrodes implanted in their brains and may...
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Dr. Ladan Jiracek - My PhD Defense, LCP Neural Implants, and What’s Next
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this solo episode of the Neural Implant Podcast, host Dr. Ladan Jiracek shares the story behind finally completing his PhD at the University of Florida - from the highs of passing his dissertation defense to the long, frustrating, and deeply technical journey of developing liquid crystal polymer (LCP)-based neural implants. I break down why LCP is so promising for long-term implantable devices, how delamination and bonding challenges became the core focus of his dissertation, and what it took to fabricate ultra-thin polymer electrodes approaching “biological invisibility.” I also...
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Paul Goode: Implantable Glucose Monitoring—and a Neural Interface Twist
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode, Paul Goode (Glucotrack) dives into the next wave of continuous glucose monitoring: an active, fully implantable CGM designed to deliver long-term, pacemaker-style reliability without external wearables. We discuss first-in-human progress, why implantables may change diabetes care at home, and a fascinating neural angle—how similar chemistry and form factors could be adapted to epidural glucose sensing and even paired with neural recording electrodes to capture metabolic and neural data together. If you care about closed-loop systems, chronic implants, or bridging...
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Fabio Boi on Corticale’s Ultra-Dense, Minimally Invasive Brain Interfaces
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, I speak with , Co-Founder and CSO of , an Italian neurotech company that is redefining the landscape of brain-computer interfaces. Corticale is pioneering a new generation of minimally invasive, CMOS-based neural implants that can record from thousands of neurons simultaneously—introducing their flagship technology, SiNAPS. Fabio walks us through how SiNAPS achieves single-cell resolution recordings via its 1024-electrode array, enabling high-fidelity access to both action potentials and local field potentials deep within cortical tissue. We...
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Ben Woodington on Coherence Bio's Revolutionary Cancer Reprogramming Approach
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, we sit down with , co-founder of , a groundbreaking medical technology company pioneering a new frontier in cancer treatment. By integrating neurotechnology, neurobiology, and machine learning, Coherence is building a platform that doesn't just fight cancer—it manages it in real time. Ben shares how Coherence is moving beyond the traditional "cut, burn, poison" model of oncology, and instead focusing on precision neuromodulation to monitor and control cancer progression—offering hope for 24/7 adaptive treatment with fewer side effects and...
info_outlineSteven Plymale is the CEO of MyndTec. He joined the firm in late 2017 and has more than 25 years of experience in the medical device industry. Previously, he was CEO of Profound Medical, bringing the company from a small six-person team to going public in 2015 in an IPO that raised $60 million. Plymale was also with Xltek, now a division of Natus Medical, and Claron Technologies.
Milos Popovic is the Director of the Toronto Rehabilitation Institute (KITE) and professor in the Institute of Biomaterials and Biomedical Engineering at the University of Toronto. He is also the co-founder and director of the MyndTec. Popovic’s decade of research and randomized clinical trials with stroke and spinal cord injury populations led to the development of the MyndMove device.
Takeaways:
Multidisciplinary teams help to build a successful rehabilitation institute.
Translation of rehabilitation technology is not easy but it can be fun.
It is important to harness neuroplasticity in the body and the brain to achieve successful long-lasting outcomes in rehabilitation.
[0:00] Steven Plymale and Milos Popovic introduced themselves to kick off the conversation with Jen French from Neurotech Reports and Ladan.
[0:35] Milos Popovic describes how RehabWeek 2019 ended up being hosted in Toronto, the first time the event was held in North America, and the plan his team put together
[1:32] Popovic describes his career journey from a nuclear engineer to director of an innovative rehabilitation research center and entrepreneur.
[3:33] Discussion of the building of the rehabilitation institute in Toronto Health Network with a team of 90 people and the importance of working directly with patients.
[4:58] Popovic describes the translation of technology from lab to the marketplace particularly in functional electrical stimulation and human clinical trials to a start-up company.
[6:24] Steven Plymale describes how he was introduced to MyndTec and his initiation into a small, struggling start-up company. Hear how he was convinced that electrical stimulation is not voodoo science
[7:50] Plymale and Popovic describe the MyndMove device.. Discussion ensues about the impact on upper extremity rehabilitation and the involvement of the brain, the melody of the neural activity, and how this therapy capitalizes on the neuroplasticity in the brain.
[12:02] Plymale discusses the current stage of MyndMove in the project development spectrum including regulatory approvals, raising capital investment, and pricing model.
[15:26] What is the target market for the MyndTec neural re-education device? Plymale also talks about their pursuit for clinical partners, their strategic focus and the economics of the medical device as an early stage venture.
[18:06] Steven Plymale talks about his career journey in the medical device industry and how he enjoys start-up ventures.
[19:25] Popovic concludes talking about what excites him at RehabWeek and the potential relationships building from this meeting.