NeuroCatch's Bimal Lakhani on building a vital sign for the brain
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
Release Date: 09/05/2023
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
did the keynote talk at the . I was able to sit down with her and talk to learn more about her auditory processing selectivity research. Top 3 Takeaways: Nurses especially can get used to beeping and alarms which can be dangerous for patients. "Under anesthesia, you see some basic responses, but they are different than when you engage the, let's say, an animal in an awake state, and then when they are awake and actually behaving and engaging with the system" Audio recordings can be tuned to remove ambient noise but they need to be perfectly calibrated to distances between microphones. ...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
Suraj Mudichintala is a Senior Associate at Action Potential Capital which is GSK's bioelectronic medicine venture fund. Top 3 Takeaways: "Our fund is different in that we invest actually directly off of GSK's balance sheet. So we're what's called an evergreen fund where we don't actually have a fund size" "The way that I think about it is that a VC is really paid to allocate capital but really is really paid to think. You really have to think about what is the next space or the next technology that could disrupt a space? And because of that, it's a much you often have to take a much more...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
Balint Varkuti is the CEO of CereGate which unlocks new capabilities for existing neuromodulation technologies using software. Top 3 Takeaways: "the brain is naturally wired for pattern perception for learning, and that's really what we do. We send signals that the brain very quickly can pick up." "You do not need to exclusively be focused mentally, consciously on interpreting these signals. Rather it becomes second nature. Our favourite analogy is saying it is like braille for the brain." "With hardware, you sometimes have simply the disadvantage that you are married to the time point when...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
returns to the podcast to give an update about his work at the and the work at . Top 3 Takeaways: "Two years we discovered that a drug called Famotidine, which is sold as a generic drug Pepcid AC is actually a pharmacological or a drug-based vagus nerve stimulator. And we proved first in mice that famotidine placed directly in very small amounts placed directly in the brains of mice activates the vagus nerve. And this in turn turned off cytokine storm, which of course is a big problem in Covid 19" "A company that I've co-founded, Setpoint Medical, is currently deep into clinical trials in...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
is the founder and CEO of which uses wearable EEG caps to quantitatively measure cannabis experiences. Top 3 Takeaways: "The reason why the government funded us was to use this for safety and law enforcement" "The combination of features that AI is finding is something that we haven't really focused on studying and trying to understand. It's a black box today that, is accurately and objectively characterizing the psychoactive effects, but we don't exactly know what they mean." "Based on this neuroscience-driven research proving the onset time of the beverage, within two weeks [the...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
is the President and CEO of which is commercializing the Monarch eTNS System, the first non-drug treatment for pediatric ADHD cleared by the FDA. Top 3 Takeaways: NeuroSigma is commercializing the Monarch eTNS system, a wearable medical device that stimulates the trigeminal nerve on the forehead, as a treatment for neurologic and neuropsychiatric indications. The Monarch eTNS System is FDA cleared as a treatment for pediatric ADHD, ages 7 – 12. Clinical trials in this population show a response rate of 50% with a only mild side effects observed in clinical trials to date. NeuroSigma...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
is the President and Chief Product Officer at which is a company looking to commercialize Brain-Computer Interfaces using a minimally implantation method and a soft electrode device. ***This podcast is sponsored by Iris Biomedical, check out their Neurotech Startup Services Top 3 Takeaways "The combination of both the nature of our thin film and the surgical innovations that we bring enables us to bring cortical surface neurotechnology to patients in a minimally invasive fashion." "Having 10 times the amount of money at an early stage before you actually solve some of the key problems can...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
Lothar Krinke is the CEO and Board Member of Newronika which is an adaptive Deep Brain Stimulator company looking to improve patient outcomes in things like Parkinson's and Essential Tremor. ***This podcast is sponsored by Iris Biomedical, check out their Neurotech Startup Services Top 3 Takeaways: "the one thing we do need to address is really the cost. The cost driver of Deep Brain Stimulation isn't the manufacturing of the system. Now, that's not cheap either it's certainly less than $10,000. How expensive is brain surgery, particularly functional brain surgery? How expensive is it to...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
is a neurosurgery clinical lecturer at the University of Cambridge and fellow at The Walton Centre in Liverpool, UK. He is interested in tackling basic and translational challenges for the development of the next generation of neural bioelectronics. ***This podcast is sponsored by Ripple Neuro, check out their Neuroscience Research Tools Top 3 Takeaways: "My favorite procedure is the procedure that works and you see the patient after that is is a changed patient." "You come out from medical school like age 23 or 24. Then you get to a general medical program which in the...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
is the Head of Commercialization at , a wearable neurostimulator sleeve for those with neuromuscular disease ***This podcast is sponsored by Iris Biomedical, check out their Neurotech Startup Services Top 3 Takeaways: "There isn't any individualized training that needs to happen. What needs to happen is the identification of which muscle groups need support and have those turned on and programmed in intensity appropriately." "We were able to improve door sub selection and inversion in more than 90% of our participants." "There's nothing like getting an appreciation for a problem like the...
info_outlineBimal Lakhani is the Vice President of Product Development at HealthTech Connex and NeuroCatch, a recent startup targeting the analytics of brain disorder diagnosis and improvements. He is also Associate Professor at the University of British Columbia in Vancouver, Canada. He holds a PhD in Rehabilitation Science. This conversation talks about the company, science behind it and where it is going in the future.
Takeaways:
We currently do not have a quick mechanism to check out brain health.
Clinical interfaces need to intuitive and easy to use for the clinician.
How is your brain today? Can we bring people to check their brain health like they check their smartphone?
[0:00] Jen French from Neurotech Reports kicks off the introductions on the RehabWeek exhibit floor.
[0:33] Bimal Lakhani describes the new venture of NeuroCatch to meet the need to get a comprehensive matrix of the brain in the clinical setting, in otherwords the “vital signs” of the brain.
[2:33] Lakhani talks about the NeuroCatch platform technology as a neurodiagnostic tool and their strategy for hardware industry partnerships.
[3:33] Description of the target areas for NeuroCatch and the gap in clinical need and the focus of their current research including concussion and other brain injuries.
[5:04] How is your brain doing today? Lakhani also describes the device and what it does.
[7:08] The walk-through of the software tool interface for an EEG evaluation and the keep it simple approach.
[11:19] The NeuroCatch device is approved for clinical use in Canada. Lakhani describes the other markets on their radar.
[11:53] Discussion of data collection and cybersecurity along with their relationship with clinical partners.
[1:26] What is the target market for the MyndTec neural re-education device? Plymale also talks about their pursuit for clinical partners, their strategic focus and the economics of the medical device as an early stage venture.
[12:36] Description of HeuroCanada partnership and clinical adoption in rehabilitation setting. He also talks about the parent company, HealthTech Connex, and their relationship with Helius Medical.
[14:25] Lakhani discusses the next steps for NeuroCatch and their future focus for people to be conscious of their brain health.