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NeuroCatch's Bimal Lakhani on building a vital sign for the brain

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Release Date: 06/28/2019

Steve Goetz: Revolutionizing Mental Health Treatment as CTO of Motif Neurotech show art Steve Goetz: Revolutionizing Mental Health Treatment as CTO of Motif Neurotech

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is now the Chief Technology Officer at which is developing a minimally invasive neural implant for the treatment of depression and mental health issues. Steve was at Medtronic for 26 years before moving over to the startup landscape. Top 3 Takeaways:  "Starting a big program that you don't know how to finish is a very expensive endeavor, and so you want to really shake out all the science risk, all the technology risk,  be pretty sure you can execute a thing before you turn on that big engine because it's expensive once you go" "We know stimulation of the dorsal lateral...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is a research group leader at the Central European Institute of Technology () located in Brno, Czech Republic. There he studies neural implant fabrication and materials specializing in silicon, parylene, and polyimide devices. He has also started to designs and fabricate devices on a contract basis for other research groups and companies. And, his institute is the one that has been recently sponsoring the podcast! This podcast is sponsored by CEITEC Nano, check out their Neurotech Device Manufacturing Capabilities  Top 3 Takeaways: "You can just buy stuff on the internet very simple red...

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Gene Fridman on his freeform stimulator allowing for more neural stimulation possibilities show art Gene Fridman on his freeform stimulator allowing for more neural stimulation possibilities

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is an Associate Professor in the Department of Otolaryngology Head and Neck Surgery and also has appointments with the Department of Biomedical Engineering and the Department of Electrical and Computer Engineering. His research is in the areas of bioinstrumentation and neural engineering. In this episode we talk about his freeform nerual stimulator which allows for DC and any other waveforms without any electrolytic effects on the electrodes. This opens up many possibilities for neural stimulation. We also talk about his startup Aidar which is like a 'tricorder' all-in-one medical diagnostic...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

comes on to talk about the latest new from , which has developed the Stentrode as well as the new Synchron Switch. Kurt talks about his new role as Chief Commercial Officer and where the company is heading. ***This podcast is sponsored by CEITEC Nano, check out their Neurotech Device Manufacturing Capabilities *** Top three takeaways:  1. "The beauty of this approach is that the blood vessels are an amazing place. To be able to put implants and we've, we're leveraging really decades of science and medical devices in say, the coronary space and the heart space. We know that these...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Pawel Soluch is a returning guest who goes over his work at , then his consulting at , and now finally he talks about the program that he is launching with me! Top 3 Takeaways: Pawel and I (Ladan) are launching the Medtech Coaching program which will be aimed at helping medical device executives gain success in their businesses Coaching is different from consulting in that we do not generate anything for you but instead help you to become the best medtech executive you can possibly be In addition to group coaching we will also be offering individual coaching and also a retreat in January...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

did the keynote talk at the . I was able to sit down with her and talk to learn more about her auditory processing selectivity research. Top 3 Takeaways:  Nurses especially can get used to beeping and alarms which can be dangerous for patients. "Under anesthesia, you see some basic responses, but they are different than when you engage the, let's say, an animal in an awake state, and then when they are awake and actually behaving and engaging with the system" Audio recordings can be tuned to remove ambient noise but they need to be perfectly calibrated to distances between microphones. ...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Suraj Mudichintala is a Senior Associate at Action Potential Capital which is GSK's bioelectronic medicine venture fund. Top 3 Takeaways: "Our fund is different in that we invest actually directly off of GSK's balance sheet. So we're what's called an evergreen fund where we don't actually have a fund size" "The way that I think about it is that a VC is really paid to allocate capital but really is really paid to think. You really have to think about what is the next space or the next technology that could disrupt a space? And because of that, it's a much you often have to take a much more...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Balint Varkuti is the CEO of CereGate which unlocks new capabilities for existing neuromodulation technologies using software. Top 3 Takeaways: "the brain is naturally wired for pattern perception for learning, and that's really what we do. We send signals that the brain very quickly can pick up." "You do not need to exclusively be focused mentally, consciously on interpreting these signals. Rather it becomes second nature. Our favourite analogy is saying it is like braille for the brain." "With hardware, you sometimes have simply the disadvantage that you are married to the time point when...

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Kevin Tracey returns to the podcast to give an update about his work at the Feinstein Institutes, the field of bioelectronic medicine and exciting vagus nerve clinical trials underway show art Kevin Tracey returns to the podcast to give an update about his work at the Feinstein Institutes, the field of bioelectronic medicine and exciting vagus nerve clinical trials underway

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

returns to the podcast to give an update about his work at the and the work at . Top 3 Takeaways: "Two years we discovered that a drug called Famotidine, which is sold as a generic drug Pepcid AC is actually a pharmacological or a drug-based vagus nerve stimulator. And we proved first in mice that famotidine placed directly in very small amounts placed directly in the brains of mice activates the vagus nerve. And this in turn turned off cytokine storm, which of course is a big problem in Covid 19" "A company that I've co-founded, Setpoint Medical, is currently deep into clinical trials in...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is the founder and CEO of which uses wearable EEG caps to quantitatively measure cannabis experiences. Top 3 Takeaways: "The reason why the government funded us was to use this for safety and law enforcement" "The combination of features that AI is finding is something that we haven't really focused on studying and trying to understand. It's a black box today that, is accurately and objectively characterizing the  psychoactive effects, but we don't exactly know what they mean." "Based on this neuroscience-driven research proving the onset time of the beverage, within two weeks [the...

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More Episodes

Bimal Lakhani is the Vice President of Product Development at HealthTech Connex and NeuroCatch, a recent startup targeting the analytics of brain disorder diagnosis and improvements. He is also Associate Professor at the University of British Columbia in Vancouver, Canada. He holds a PhD in Rehabilitation Science. This conversation talks about the company, science behind it and where it is going in the future.

Takeaways:
We currently do not have a quick mechanism to check out brain health.
Clinical interfaces need to intuitive and easy to use for the clinician.
How is your brain today? Can we bring people to check their brain health like they check their smartphone?


[0:00] Jen French from Neurotech Reports kicks off the introductions on the RehabWeek exhibit floor.
[0:33] Bimal Lakhani describes the new venture of NeuroCatch to meet the need to get a comprehensive matrix of the brain in the clinical setting, in otherwords the “vital signs” of the brain.
[2:33] Lakhani talks about the NeuroCatch platform technology as a neurodiagnostic tool and their strategy for hardware industry partnerships.
[3:33] Description of the target areas for NeuroCatch and the gap in clinical need and the focus of their current research including concussion and other brain injuries.
[5:04] How is your brain doing today? Lakhani also describes the device and what it does.
[7:08] The walk-through of the software tool interface for an EEG evaluation and the keep it simple approach.
[11:19] The NeuroCatch device is approved for clinical use in Canada. Lakhani describes the other markets on their radar.
[11:53] Discussion of data collection and cybersecurity along with their relationship with clinical partners.
[1:26] What is the target market for the MyndTec neural re-education device? Plymale also talks about their pursuit for clinical partners, their strategic focus and the economics of the medical device as an early stage venture.
[12:36] Description of HeuroCanada partnership and clinical adoption in rehabilitation setting. He also talks about the parent company, HealthTech Connex, and their relationship with Helius Medical.
[14:25] Lakhani discusses the next steps for NeuroCatch and their future focus for people to be conscious of their brain health.