Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐จ New breakthrough in hypertension care! ๐ The Launch-HTN trial shows lorundrostat โ a selective aldosterone synthase inhibitor โ significantly lowers systolic BP in patients with uncontrolled or treatment-resistant hypertension. ๐ โ16.9 mmHg vs โ7.9 mmHg with placebo (P < .001) ๐งช Safe, well-tolerated, and effective across subgroups. A potential game-changer in aldosterone-targeted therapy! ๐๐ฅ #Hypertension #Cardiology #ClinicalTrials #PrecisionMedicine
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
Our latest podcast episode unpacks the 2025 JAMA Review on Type 2 Diabetes ๐ฌ๐ We explore: โ New diagnostic strategies โ Why GLP-1s & SGLT2is are game-changers โ How lifestyle change can lead to remission โ Individualizing A1C goals in real-world care ๐๏ธ Episode Title: โDiagnose, Personalize, Optimize: The 2025 Diabetes Blueprintโ ๐ Essential listening for clinicians, educators, and innovators in endocrine & cardiometabolic care. ๐ Tune in now and share with your network! #Type2Diabetes #CardiometabolicCare #GLP1 #SGLT2...
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
How we sleep tonight shapes how we move tomorrow! ๐๐โโ๏ธ In a large-scale wearable study (๐ฑWHOOP & Fitbit data from >25,000 adults), researchers found: โ Sleeping earlier than usual boosts next-day physical activity โ Longer or later sleep = less movement ๐ฅ Max gains came from consistent sleep duration + early bedtime Letโs rethink our ๐ค to power our ๐ฅ! ๐ฃ Public health campaigns should promote sleep and exercise togetherโnot in competition. ๐ PNAS, June 2025 | doi: #SleepHealth #PhysicalActivity #WearableTech #Chronobiology...
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐งฌ Curious why we age? ๐ฐ๏ธ From DNA damage to developmental programs gone rogue, this new podcast episode dives deep into 17 theories of ageing โ some classic, some controversial. ๐ We explore wear-and-tear, free radicals, telomeres, mitochondria, stem cell exhaustion, and the rising stars of epigenetic drift and hyperfunction theory. ๐๏ธ Whether youโre a scientist, clinician, or just fascinated by the biology of time, tune in to uncover what really drives the ageing processโand what might one day slow it down. ๐ง Listen now: โWrinkle, Rust, and...
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
Refractory Angina: Time to Rethink the Diagnosis ๐ซ๐ฅ Chest pain that defies stents and statins? It may not be your typical obstructive CAD. This podcast unpacks the redefinition of refractory angina โ spotlighting INOCA, CMD, vasospasm, and myocardial bridging ๐ฌโ๏ธ We explore PET, CMR, CFVR, and wire-based diagnostics ๐ โ and why a multidisciplinary Angina Heart Team is key to transforming care ๐ฉโโ๏ธ๐จโโ๏ธ๐ง ๐ง Listen in as we chart a course from frustration to precision โ because even stubborn angina has a story and a solution. ...
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐ฌ๐ New insights from Nature Aging: Inflammaging isnโt universal! A fascinating cross-cultural study comparing Italy ๐ฎ๐น, Singapore ๐ธ๐ฌ, Bolivia ๐ง๐ด, and Malaysia ๐ฒ๐พ shows that age-related inflammationโlong considered a hallmark of agingโmay actually be a product of industrialized environments. Populations like the Tsimane (Bolivia) and Orang Asli (Malaysian), despite high infection loads, show minimal correlation between cytokines and age-related disease. ๐ Conclusion: Inflammaging is not destinyโitโs context. ๐งช Read the...
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๐จ AI vs Sudden Cardiac Death in HCM ๐ซ๐ค Exciting new study published in Nature Cardiovascular Research showcases MAARS, a multimodal AI model that dramatically improves risk prediction for sudden arrhythmic death in hypertrophic cardiomyopathy patients. ๐ MAARS outperformed current guidelines with AUROC of 0.89 (internal) and 0.81 (external) ๐ง Integrated data: LGE-CMR ๐งฒ, EHR ๐, and echo/CMR reports ๐ป โ๏ธ Demonstrated fairness across age and sex subgroups ๐ Transparent predictions via Shapley values and attention heatmaps A leap toward...
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
โVax to the Future: Cancer Immunity Revolution ๐งฌ๐โ Cancer vaccines are no longer a promise โ theyโre a precision revolution. From HBV and HPV to cutting-edge mRNA-based neoantigen vaccines, we explore how tumor sequencing + AI + immune checkpoint inhibitors are reshaping oncology. ๐ Real data from trials in melanoma, ccRCC, and pancreatic cancer โ๏ธ PD-1 inhibitors meet targeted T cells ๐ A safer, scalable future for cancer care ๐ง Tune in to Got Knowledge Doc as we decode this game-changing viewpoint from JCI โ โVaccines in Cancer Treatment...
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐จ New Findings on Aspartame & Heart Health! ๐ฌ๐ซ A groundbreaking study in Cell Metabolism reveals how aspartame, a common artificial sweetener, may worsen atherosclerosis via an insulin-triggered inflammatory pathway involving the CX3CL1-CX3CR1 axis. ๐งช Key insights from mice and monkeys: โ Aspartame spikes insulin via vagus nerve stimulation โ Elevated insulin boosts CX3CL1 expression in endothelial cells โ CX3CL1 recruits inflammatory monocytes โก๏ธ plaque growth & instability ๐งฌ Blocking CX3CR1 in monocytes stopped plaque progression entirely....
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Saint Augustine of Hippo (354โ430 CE), a prominent theologian, philosopher, and bishop in Roman North Africa, profoundly influenced Western Christianity and philosophy. Known for works like Confessions, The City of God, and On Christian Doctrine, he developed doctrines on original sin, grace, just war, and ecclesiology. His thoughts shaped medieval theology, inspired Protestant Reformers, and continue to impact Christian teachings.
info_outline๐ง Dr RR Baliga's Internal Medicine Podcasts for Physicians: MUST KNOW FACTs about Hyponatremia.
from a chapter on
Electrolyte Disorders
by
John J Chang, MDAssistant Professor
&
Professor of Medicine (Nephrology);
Yale School of Medicine
Not Medical Advice or Opinion