Psychological Impact of Quarantine: How To Reduce it
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Release Date: 03/18/2020
π₯ Old Drugs, New Power: Amiloride vs Spironolactone in Resistant Hypertension
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π©Ί New hope for #ResistantHypertension! A 12-week RCT π°π· shows π amiloride is noninferior to spironolactone in lowering SBP π Fewer side effects, similar BP drop! But spironolactone may still reign π for organ protection π«π§ π§ͺ #Hypertension #Cardiology #JAMA2025
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π§ͺ Precision for One, Promise for Many: CRISPR Meets the Clinic--A New Era in Rare Disease Therapy
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π§¬β¨ A baby with deadly CPS1 deficiency (which results in elevated ammonia levels) gets a custom-made gene editβdelivered by lipid nanoparticlesβin just 6 months! π Ammonia levels down, no hospitalizations, and hope up. N-of-1? More like Future-of-Many. π‘πΆπ¬ #GeneTherapy #PrecisionMedicine #RareDisease
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π₯ Smoldering Systems: Staging Systemic Metabolic Disorder Before It Ignites
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π¨ New framework alert! Systemic Metabolic Disorder (SMD) gets a clinical staging makeover 𧬠From reversible risks π± to systemic damage π₯βthis EAS consensus guides timely, targeted care π― #MetabolicHealth #Cardiology #PrecisionMedicine #SMD π©Ίπ
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Dr RR Baliga's Philosophical Discourses: Pyrrho (Greece, c. 360β270 BCE) β Founder of Pyrrhonism
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Pyrrho of Elis (c. 360β270 BCE) was an ancient Greek philosopher and founder of Pyrrhonism, a school of philosophical skepticism. He advocated for epochΓ© (suspension of judgment) as a path to ataraxia (peace of mind). Influenced by his travels to India with Alexander the Great, Pyrrho believed that nothing could be definitively known and that by refraining from beliefs, one could achieve tranquility. His teachings laid the foundation for later skeptical thought in philosophy and medicine.
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𧬠Target ANGPTL3, Tame the Lipids, Transform the Risk
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
𧬠New hope for lipid warriors! Solbinsiran (siRNA) slashed apoB π©Έ, TGs π, LDL-C π & liver fat π« in just 205 pts with mixed dyslipidaemia. Safe β Durable β Quarterly dosing? Maybe β Letβs talk outcomes! π― #PROLONGANG3 #RNAtherapy #CardioTwitter #LipidLowering
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π₯ Watch, Wait, or Wage War? The Prostate Cancer Playbook
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π§ββοΈ Prostate cancer is the most common cancer in US men. π§ͺ PSA testing? π Itβs all about shared decision-making. 𧬠From Gleason scores to PSMA-PET, precision reigns. π ARPIs & ADT = survival gains in advanced disease. βοΈ Screen smart. Treat right. Save lives. #ProstateCancer #MensHealth #Oncology π§ πͺ
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Triglycerides, Trials, and Triumph π§ππ: The ANGPTL4 Story
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π¨ New frontier in lipid-lowering! 𧬠Blocking ANGPTL4 with MAR001 slashed triglycerides & remnant cholesterol by >50% π‘οΈ Safe, well-tolerated, no lymph node issues π‘ Promising for residual ASCVD risk Next step? Big trials, big answers! ππ« #LipidScience #CardioTwitter #PrecisionMedicine
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Cracking the Code of Short Sleepers π§ ππ΄
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Why do some people sleep just 4 hours and feel great? π΄πͺ A new study links the 𧬠SIK3-N783Y mutation to natural short sleep! Less sleep, more delta power π§ β‘ ππ #SleepScience #Genetics #SIK3 #ShortSleepers
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π₯ IL-6, Inflammation, and Irregular Beats: The Cytokine Cascade Driving Post-Op AFib
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π« Post-op AFib? Blame IL-6! New @JClinInvest study shows IL-6 β‘οΈ STAT3 β‘οΈ CaMKII β‘οΈ RyR2 leak triggers post-op AFib. 𧬠Macrophage IL-6RΞ± is the match. π§― TTI-101 & KN-93 douse the flame. β‘ Targeting IL-6 signaling = future Rx? #CardioTwitter #AFib #Inflammation #JCI
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Good Carbs, Great Life, Golden Years π₯¦β¨π΅
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π₯¦π Want to age like fine wine? Choose high-quality carbs! In a 32-year study of 47K women, fiber-rich carbs (from πΎ, π₯, π±) boosted odds of healthy aging π§ πͺπ§ββοΈ Refined carbs? Not so kind. #HealthyAging #NutritionMatters #WomensHealth π§¬ππ
info_outlinePsychological Impact of Quarantine: How To Reduce it
Dr RR Baliga's 'Got Knowledge Doc' Podcasts for Physicians
Lancet 2020;395:912-920
Dr Samantha Brooks et al, King's College, London, UK
Not Medical Advice or Opinion