Hot of the Press: Lopinavir–Ritonavir NOT Effective in Severe COVID19 NEJM
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Release Date: 03/18/2020
🧪 Reset, Rewind, Rejuvenate: Chemical Reprogramming Against Aging
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧬 Rewinding Cellular Time with Chemistry! 🧪 A groundbreaking study just showed that a two-chemical cocktail (2c) — Tranylcypromine + Repsox — can reverse aging markers in human cells and extend C. elegans lifespan by 42%! 🐛💥 Unlike gene-based reprogramming, this method is safer, scalable, and preserves cell identity. Think of it as “Yamanaka lite” — with big implications for aging and longevity science. 🧠💊 #Longevity #Epigenetics #Rejuvenation #Biotech #AgingResearch #Lifespan
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From ABI to Amputation: Navigating PAD with Precision
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚶♂️💔 Just recorded a podcast on Peripheral Artery Disease (PAD) – a silent threat affecting 200M+ people worldwide. We unpack the latest 2024 ACC/AHA guidelines: ✅ When to screen 💊 What therapies work 🦿 How to save limbs & lives Tune in to walk away smarter. 👣🎙️ #PAD #Cardiology #Guidelines #Prevention #LimbSalvage
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Osteoporosis Uncovered: Risk, Resilience, and Recovery 🔍🛡️🔄
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Just finished reviewing the latest JAMA 2025 article on osteoporosis by Morin et al. — a must-read for anyone managing bone health in aging adults! 📉 Despite advances, 70% of fractures occur in those without DXA-defined osteoporosis. 💊 Treatment isn’t just about T-scores — it’s about fracture risk, fall prevention, and smart sequencing of antiresorptive and anabolic therapies. 🏋️♀️ Plus, lifestyle matters: resistance training, calcium, vitamin D, and proactive screening save lives. 📈 Fracture Liaison Services (FLS) boost treatment initiation from 17%...
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🧬 Targeting Aldosterone: A New Shot at Hypertension 🎯💥
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚨 New breakthrough in hypertension care! 💊 The Launch-HTN trial shows lorundrostat — a selective aldosterone synthase inhibitor — significantly lowers systolic BP in patients with uncontrolled or treatment-resistant hypertension. 📉 −16.9 mmHg vs −7.9 mmHg with placebo (P < .001) 🧪 Safe, well-tolerated, and effective across subgroups. A potential game-changer in aldosterone-targeted therapy! 🔄💥 #Hypertension #Cardiology #ClinicalTrials #PrecisionMedicine
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Diagnose, Personalize, Optimize: The 2025 Diabetes Blueprint
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Our latest podcast episode unpacks the 2025 JAMA Review on Type 2 Diabetes 🔬💊 We explore: ✅ New diagnostic strategies ✅ Why GLP-1s & SGLT2is are game-changers ✅ How lifestyle change can lead to remission ✅ Individualizing A1C goals in real-world care 🎙️ Episode Title: “Diagnose, Personalize, Optimize: The 2025 Diabetes Blueprint” 📈 Essential listening for clinicians, educators, and innovators in endocrine & cardiometabolic care. 👉 Tune in now and share with your network! #Type2Diabetes #CardiometabolicCare #GLP1 #SGLT2...
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Early to Bed, Stronger Steps Ahead 💤💪👣”
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
How we sleep tonight shapes how we move tomorrow! 📉🏃♂️ In a large-scale wearable study (📱WHOOP & Fitbit data from >25,000 adults), researchers found: ✅ Sleeping earlier than usual boosts next-day physical activity ❌ Longer or later sleep = less movement 🔥 Max gains came from consistent sleep duration + early bedtime Let’s rethink our 💤 to power our 💥! 📣 Public health campaigns should promote sleep and exercise together—not in competition. 📄 PNAS, June 2025 | doi: #SleepHealth #PhysicalActivity #WearableTech #Chronobiology...
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Wrinkle, Rust, and Rewind: 17 Theories of Why We Age
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧬 Curious why we age? 🕰️ From DNA damage to developmental programs gone rogue, this new podcast episode dives deep into 17 theories of ageing — some classic, some controversial. 🔍 We explore wear-and-tear, free radicals, telomeres, mitochondria, stem cell exhaustion, and the rising stars of epigenetic drift and hyperfunction theory. 🎙️ Whether you’re a scientist, clinician, or just fascinated by the biology of time, tune in to uncover what really drives the ageing process—and what might one day slow it down. 🧠 Listen now: “Wrinkle, Rust, and...
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💥 Beyond the Block: Cracking the Code of Chest Pain 🔬❤️
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Refractory Angina: Time to Rethink the Diagnosis 🫀💥 Chest pain that defies stents and statins? It may not be your typical obstructive CAD. This podcast unpacks the redefinition of refractory angina — spotlighting INOCA, CMD, vasospasm, and myocardial bridging 🔬⚙️ We explore PET, CMR, CFVR, and wire-based diagnostics 🔎 — and why a multidisciplinary Angina Heart Team is key to transforming care 👩⚕️👨⚕️🧠 🎧 Listen in as we chart a course from frustration to precision — because even stubborn angina has a story and a solution. ...
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Inflammaging: Myth, Marker, or Mismatch? 🧪❓🌐
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🔬🌍 New insights from Nature Aging: Inflammaging isn’t universal! A fascinating cross-cultural study comparing Italy 🇮🇹, Singapore 🇸🇬, Bolivia 🇧🇴, and Malaysia 🇲🇾 shows that age-related inflammation—long considered a hallmark of aging—may actually be a product of industrialized environments. Populations like the Tsimane (Bolivia) and Orang Asli (Malaysian), despite high infection loads, show minimal correlation between cytokines and age-related disease. 📉 Conclusion: Inflammaging is not destiny—it’s context. 🧪 Read the...
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🧠❤️ Predict. Prevent. Protect: AI’s Lifesaving Role in HCM
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚨 AI vs Sudden Cardiac Death in HCM 🫀🤖 Exciting new study published in Nature Cardiovascular Research showcases MAARS, a multimodal AI model that dramatically improves risk prediction for sudden arrhythmic death in hypertrophic cardiomyopathy patients. 📊 MAARS outperformed current guidelines with AUROC of 0.89 (internal) and 0.81 (external) 🧠 Integrated data: LGE-CMR 🧲, EHR 📋, and echo/CMR reports 💻 ⚖️ Demonstrated fairness across age and sex subgroups 🔍 Transparent predictions via Shapley values and attention heatmaps A leap toward...
info_outlineHot of the Press: Lopinavir–Ritonavir NOT Effective in Severe COVID19 NEJM March 18, 2020
Dr RR Baliga's 'Got Knowledge Doc' Podcasts for Physicians
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