Prevention of Venous Thromboembolism: AHA Call for Action May 2020
Dr. RR Baliga's 'Podkast for the Kurious Doc'
Release Date: 05/26/2020
Lower LDL-C earlier, protect longer—the artery remembers every LDL it has ever seen.
Dr. RR Baliga's 'Podkast for the Kurious Doc'
Evolocumab steps into primary prevention—quietly, convincingly. In JAMA, the VESALIUS-CV analysis shows that high-risk patients with diabetes without known atherosclerosis experienced a 31% relative reduction in first MACE (HR 0.69), with LDL-C lowered to ~52 mg/dL. The signal is clear: earlier, deeper lipid lowering matters. Yet questions remain—cost, long-term safety, and who benefits most. Are we ready to treat risk before disease declares itself? 🧠💉📉 #JAMA #Cardiology #Prevention
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Rethinking Asymptomatic Aortic Stenosis: Early Knife, Better Survival 🫀
Dr. RR Baliga's 'Podkast for the Kurious Doc'
A quiet valve, a loud message. 🫀 The 10-year follow-up of the RECOVERY trial in The New England Journal of Medicine shows that early surgery in asymptomatic very severe aortic stenosis is not premature—it is protective. A striking reduction in cardiovascular mortality (HR 0.10, P=0.002) and sustained divergence of Kaplan–Meier curves challenge the long-held “watchful waiting” paradigm. Perhaps we are not treating symptoms—but preventing myocardial destiny. #Cardiology #AorticStenosis #NEJM #PrecisionMedicine
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Atheroma Begins Early. Prevention Must Too. See Beyond 10 Years. Think 30 Years. Act Now.
Dr. RR Baliga's 'Podkast for the Kurious Doc'
Cardiology stands at a quiet inflection point. We have spent decades treating plaque—yet the real opportunity lies upstream: preventing atheroma before it begins. Emerging evidence reminds us that cumulative LDL exposure, not just snapshots of risk, shapes lifelong cardiovascular destiny. A shift is underway: → From 10-year risk to lifetime risk → From reactive care to proactive prevention → From treating disease to preserving vascular resilience Lower LDL earlier. Sustain it longer. That is not just prevention—it is strategy, science, and stewardship. #Cardiology #Prevention...
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Resistant Hypertension: Diagnose, Decode, Defeat 🧩
Dr. RR Baliga's 'Podkast for the Kurious Doc'
Resistant Hypertension remains one of the most under-recognized yet high-risk phenotypes in cardiovascular medicine. Nearly 1 in 5 treated patients meet criteria for apparent resistance—and up to half may reflect nonadherence or white-coat effect. This concise visual series distills key insights from a recent JAMA review on diagnosis, pathophysiology, and stepwise management—including the pivotal role of spironolactone and emerging therapies like renal denervation. Precision begins with correct classification. Treatment begins with clarity. 💡 #Hypertension...
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Sound. Mask. Mastery 🎼
Dr. RR Baliga's 'Podkast for the Kurious Doc'
Sound. Mask. Mastery 🎼 A fascinating insight from C. V. Raman reminds us that hearing is not just perception—it is physics in motion. His 1926 Nature note reveals how lower tones quietly veil higher ones, shaping what we think we hear. In music—and in science—what is hidden often matters most. #Acoustics #CVRaman #Psychoacoustics #SoundScience #NatureJournal
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Yajnavalkya: Vedic Sage • Radical Thinker • Timeless Voice 🕉️📜✨
Dr. RR Baliga's 'Podkast for the Kurious Doc'
Yajnavalkya: Vedic Sage • Radical Thinker • Timeless Voice 🕉️📜✨ What does it mean to know the Self? Long before modern philosophy, Yajnavalkya in the Brihadaranyaka Upanishad asked—and answered—with striking clarity. “Neti, Neti” (not this, not this) strips illusion, revealing the essence of consciousness—Atman as Brahman. In dialogues with Maitreyi and Gargi, he models fearless inquiry, intellectual rigor, and spiritual depth. Ancient, yet urgent. Subtle, yet transformative. #IndianPhilosophy #Vedanta #Yajnavalkya #Consciousness...
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Nutrition is no longer advice—it is biology, timing, and destiny intertwined.
Dr. RR Baliga's 'Podkast for the Kurious Doc'
Emerging insights from Nature Spotlight on Nutrition sharpen a simple truth: what we eat matters—but when and how may matter just as much. Morning coffee aligns with lower cardiovascular mortality, plant-forward diets sculpt a favorable microbiome, early-life sugar exposure imprints lifelong risk, and not all potatoes are equal—fried forms carry harm, not the humble baked. Nutrition is no longer advice—it is biology, timing, and destiny intertwined.
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Dopamine: Beyond Reward — A Broader Role
Dr. RR Baliga's 'Podkast for the Kurious Doc'
Dopamine is not just the “pleasure chemical”—it is the brain’s teaching signal 🧠✨ New insights (from Nature) suggest dopamine shapes how we learn, prioritize, and act—not only through reward, but also via attention, action, and even threat detection 🎯🔁 This evolving paradigm has profound implications for ADHD, addiction, and behavioral medicine 🩺 I’ve summarized the science into a concise slide deck for clinicians and learners. Curious to hear your thoughts—are we ready to move beyond the reward model? 🚀
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Traumatic Encephalopathy: The injury is not the blow—it is the breach and inflammation that lingers
Dr. RR Baliga's 'Podkast for the Kurious Doc'
A striking study in Science Translational Medicine reveals that the blood–brain barrier remains disrupted years after retirement in contact-sport athletes. This persistent leakiness is linked to systemic inflammation, complement activation, and measurable cognitive decline. Notably, imaging of BBB dysfunction outperformed conventional blood biomarkers—offering a potential path toward early detection of CTE risk in living individuals. The key insight: it’s not single concussions, but the cumulative burden of head trauma that shapes long-term brain health.
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Thymus: Aging, Immunity and Longevity
Dr. RR Baliga's 'Podkast for the Kurious Doc'
The thymus—long dismissed as vestigial in adults—re-emerges as a powerful biomarker of health and therapeutic response. Two Nature (2026) studies demonstrate that AI-derived thymic health independently predicts all-cause mortality, cardiovascular death, and cancer risk, while also forecasting immunotherapy outcomes across tumor types—performing comparably to PD-L1 and tumor mutation burden. This reframes aging as an immunologic continuum. The thymus may not just reflect health—it may define it. #PrecisionMedicine #Immunology #CardioOncology #AIinMedicine
info_outlineDr RR Baliga's 'Got Knowledge Doc' PodKasts for Physicians | Prevention of Venous Thromboembolism: AHA Call for Action May 2020 |
Not Medical Advice or Opinion
Henke PK, Kahn SR, Pannucci CJ, et al