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Kevin Tracey returns to the podcast to give an update about his work at the Feinstein Institutes, the field of bioelectronic medicine and exciting vagus nerve clinical trials underway

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Release Date: 03/13/2023

Christina Salchow-Hommen and Dimitry Sayenko on electrode placement and neuroplasticity show art Christina Salchow-Hommen and Dimitry Sayenko on electrode placement and neuroplasticity

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Narrative Salchow and Sayenko Dual interview episode: Christina Salchow-Hommen from Charité Universitätsmedizin in Berlin, Germany. Her presentation at RehabWeek2019 was titled “Characterization Of Optimal Electrode Configurations For Transcutaneous Spinal Cord Stimulation.” The talk presented her findings from a small trial which included 5 participants living with spinal cord injuries. In the trial, they were trying to find the optimal placements and size of surface stimulation electrodes to elicit a response rectus femoris and the tibialis anterior muscles. The study found variability...

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Bioness's Tom LeBlanc on rehabilitating hand weakness or paralysis show art Bioness's Tom LeBlanc on rehabilitating hand weakness or paralysis

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Tom LeBlanc is the Marketing Manager at Bioness, a neuroprosthetics and neural rehabilitation technology company born out of the Alfred E. Mann Foundation. Let’s listen in on his interview. He has several years of experience in marketing and communications within Bioness. Prior to joining them he was in the entertainment industry with the likes of Disney and Warner Bros. He holds an MBA from Pepperdine University. Let’s listen to our conversation with him. Takeaway: Functional electrical stimulation can be used as a neuroprosthetic for everyday tasks or as a rehabilitation device to gain...

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Cybathlon - the Olympics of Brain Computer Interfaces, man and machine work together show art Cybathlon - the Olympics of Brain Computer Interfaces, man and machine work together

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

The Swiss Federal Institute of Technology in Zurich’s Robert Reiner was one of the key figures to initiate the Cybathlon in 2016. The Cybathlon is a unique event in the development of every- day assistive devices in which people living with various disabilities compete while using the latest developments. There are six disciplines from advanced wheelchairs to FES cycling. Florian Haufe, a PhD candidate in Dr. Reiner’s lab, fills us in a little more about this premiere event and what the expect in the 2020 competition. Takeaways: 1. Showcase of technology for people with disabilities in the...

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Paul Meadows on helping found IFESS and Imthera neurostimulation show art Paul Meadows on helping found IFESS and Imthera neurostimulation

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Paul Meadows is one of the founding members of IFESS and a  veteran in the neurotech industry. He is currently the Chief Technology Officer at Imthera in the development of neurostimulation device for obstructive sleep apnea. The company was recently acquired by LivaNova. Previous Meadows was involved with neurotech development at Advanced Bionics as well as the Alfred E. Mann Foundation. Takeaways: 1. Current technology transfer developments are influenced by peer-reviewed published research. 2. Learn from the past so we don’t repeat in the future, applies to neurotech applications. 3....

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Thierry Keller Discusses Neuroprosthetic Technologies for Upper and Lower Extremity Stimulation show art Thierry Keller Discusses Neuroprosthetic Technologies for Upper and Lower Extremity Stimulation

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Thierry Keller is a researcher in , a research institute in Spain. In this episode, he discusses some of the neuroprosthetic technologies for upper and lower extremity stimulation and recording that he is working to develop in his institute. Top three takeaways: Multiple stimulation channels, such as on the transcutaneous array, can provide better resolution of functions There needs to be open communication and sharing of knowledge between technology developers, clinicians, and end users in order to maximize the positive impact of an implanted device The point of research is not just to...

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Coffee Conversation with Steven Plymale and Milos Popovic at Toronto Rehabweek 2019 show art Coffee Conversation with Steven Plymale and Milos Popovic at Toronto Rehabweek 2019

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Steven Plymale is the CEO of MyndTec. He joined the firm in late 2017 and has more than 25 years of experience in the medical device industry. Previously, he was CEO of Profound Medical, bringing the company from a small six-person team to going public in 2015 in an IPO that raised $60 million. Plymale was also with Xltek, now a division of Natus Medical, and Claron Technologies. Milos Popovic is the Director of the Toronto Rehabilitation Institute (KITE) and professor in the Institute of Biomaterials and Biomedical Engineering at the University of Toronto. He is also the co-founder and...

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David Pitino Discusses Medical Technology Innovation and Affordability show art David Pitino Discusses Medical Technology Innovation and Affordability

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

David Pitino is a health technology researcher who started the in Mount Sinai. In this episode, he discusses innovation in the health tech industry, and how such technology and the industry overall can be improved.   Top three takeaways: Communicating with your end user is critically important in solving challenges with medical technologies. One major improvement in most medical technologies is the increase in affordability of these technologies for patients. Improving the industry and technology is more important than monetary gain.   [0:00] Ladan introduces the episode and David...

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Vivian Mushahwar Discusses Neural Stimulation Technologies for Patient Rehabilitation Following Spinal Cord Injury show art Vivian Mushahwar Discusses Neural Stimulation Technologies for Patient Rehabilitation Following Spinal Cord Injury

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is a professor at the University of Alberta in the Department of Medicine, and she is in the division of . She has a bachelor’s degree in electrical engineering and a PhD in bioengineering, and has completed two postdoc positions in rehab medicine and neuroscience. In this episode, she discusses some of the technologies she is researching and developing with regards to nerve stimulation and walking/standing. Top three takeaways: Neural stimulation below levels of injury can greatly improve standing and walking performance in patients with spinal cord injury. A good understanding of...

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Debbie Backus Discusses the Development and Current Challenges of Medical Technologies for Patient Mobility show art Debbie Backus Discusses the Development and Current Challenges of Medical Technologies for Patient Mobility

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Debbie Backus is with the Shepherd Center, a rehabilitation hospital located in Atlanta, and is also the president of ACRM, a multidisciplinary organization whose mission is to help improve the lives of people with disabilities, particularly brain and spinal cord injuries. In this episode, she discusses the current technologies used to help patients with movement disabilities, how far the technologies have come, the cost-effectiveness of such technologies, and how those technologies may continue to grow in the future. Top three takeaways: Organizations such as the Shepherd Center and ACRM...

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Hocoma's Ursula Costa on helping patients gain maximum potential with  show art Hocoma's Ursula Costa on helping patients gain maximum potential with

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Ursula Costa is the Head of Clinical Affairs at Hocoma AG, an established neural rehabilitation company based in Zurich, Switzerland. She is a licensed physical therapist who has recovered herself from a spinal cord injury as a young girl and then nurtured her passion for neurorehabilitation. She holds a PhD from Universitat Autonoma de Barcelona in Physical Therapy and has held a professorship at the same university.  Takeaway: Rehabilitation technology is a tool to help the patient gain maximum potential not a tool to do the motion passively. Technology coupled with rehabilitation aids...

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Kevin Tracey returns to the podcast to give an update about his work at the Feinstein Institutes and the work at SetPoint Medical.

Top 3 Takeaways:

  • "Two years we discovered that a drug called Famotidine, which is sold as a generic drug Pepcid AC is actually a pharmacological or a drug-based vagus nerve stimulator. And we proved first in mice that famotidine placed directly in very small amounts placed directly in the brains of mice activates the vagus nerve. And this in turn turned off cytokine storm, which of course is a big problem in Covid 19"
  • "A company that I've co-founded, Setpoint Medical, is currently deep into clinical trials in the United States called ResetRA, which is on clinical trials.gov or on the SetPoint website for rheumatoid arthritis patients. And that trial is enrolling many patients up to, I think 250 patients will be studied according to the websites and we're hoping that goes very well. And we're hoping, I'm hoping that leads to FDA approval for vagus nerve stimulation in the US in the coming days or coming in the coming months"
  • "I think we're very close now to vagus nerve stimulation becoming a reality for millions of patients. And I, I hope, and I see a time when patients have the. Of  choosing vagus nerve stimulation as a simple, safe therapy instead of dangerous, expensive drugs with black box warnings that are minimally effective."

0;30 "Do you wanna introduce yourself and talk about some of your work, especially as neuromodulation pertains to the immune system?"

2:45 "So the last time when we talked it was 2020. So pandemic, everything was upside down. But then you were telling me before we started recording that it was also especially busy for you at that time. So what were you up to around then?"

6:00 What were the quantitative takeaways of the Famotidine Covid trials?

8:15 "Why didn't it become standard practice?"

11:00 "You're saying the famotidine has this effect on the vagus nerve. Does this mean we no longer need vagus nerve stimulators? Can we just take Pepcid, AC?"

15:00 Do you want to talk about the Bioelectronic Medicine Summit?

17:30 What were some of the highlights of the Summit?

 19:30 "You mentioned some interesting results. Is that something you can share now or is that something that we should be on the lookout for?"

21:30 "You were also featured recently in the Wall Street Journal and New York Times, what was that like and what were the articles about?"

23:15 "So what's exciting you now for 2023 and what's on the horizon for you for the next few years?"

27:15 "Is there anything that we didn't talk about that you wanted to mention?"