The Women's Hormone Masterclass with Dr. Kyle Gillett: A Deep Dive Into Testosterone, Dutasteride, SHBG, & Menopause Weight Gain
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Release Date: 06/22/2024
The Menopause Metabolic Storm: Why Estrogen Loss Makes Weight Gain So Hard to Escape
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Are you ready for a true masterclass? In this solo episode, I’m diving deep into estrogen and metabolic health—and trust me, this one challenged even me. Is estrogen really making you gain weight, or is the real problem what happens when it drops? If you’ve hit your 40s or 50s and suddenly nothing works anymore, you need to hear this. Why does belly fat seem to appear overnight in perimenopause? Why does your energy tank, your cravings skyrocket, and your mood feel completely hijacked? I unpack the science behind estradiol and how it impacts insulin, cortisol, thyroid, muscle,...
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Quick Hits: From Breast Cancer to Bone Health: The Uncharted Territory of HRT & Chronic Diseases in Menopause with Dr. Elizabeth Yurth
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Listen to the full peptide here: Download on Apple and on your favorite podcast platform. Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. Today we're talking about the crucial world of women's hormonal health with Dr. Elizabeth Yurth from the Boulder Longevity Institute. We discuss how hormonal imbalances impact everything from chronic disease to daily vitality. We also demystify hormone replacement therapy, emphasizing its importance beyond just reproductive...
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The Mental Health Crisis No One Is Linking to Hormones with Dr. Louise Newson
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Why are so many of us blindsided by anxiety, depression, rage, or even suicidal thoughts in midlife? And why are hormones so often left out of the conversation? I’m joined by the incredible Dr. Louise Newson, a UK-based GP and menopause specialist, to talk about something far too many women experience in silence—mental health struggles during perimenopause and menopause. We dive deep into what’s really happening in the brain when estrogen, progesterone, and testosterone start to fluctuate or decline. Could your low mood, brain fog, loss of confidence, or even a new ADHD diagnosis be...
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Copper Peptides & Exosomes: The Skin Regeneration Breakthrough for Women Over 40
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Have you looked in the mirror lately and wondered, when did my skin change like this? In this episode, I’m joined by Debbi Barber (founder of Vitali Regenerative Skincare) and Dr. Jordan Plews (a stem cell scientist and co-founder of Xytogen Biotech) to unpack what’s really happening to our skin in midlife—and what we can actually do about it. Is it just aging… or is there something deeper going on at the cellular level? We dive into copper peptides (GHK-Cu) and exosomes—what they are, where they come from, and why they might be the future of regenerative skincare. Can you really...
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The Hormone–Histamine Connection Doctors Aren’t Talking About
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
In this Hormone Hotline episode, I’m answering a powerful question about estrogen HRT, histamine intolerance, and mast cell activation during perimenopause and long COVID. Why do histamine flares explode when hormones start shifting? Is estrogen really the villain—or is something deeper driving the chaos? I share my own long battle with histamine hives, food reactions, and hormone swings—and what finally moved the needle. Why do so many women get worse on a low histamine diet over time? Could unstable estrogen levels be more triggering than estrogen itself? And what role does...
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Quick Hits: The New Science of Midlife Fat Gain + The Top Strategies for Menopause Weight Loss with Dr. Bill Campbell
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. Listen to the full episode here: Itunes: Are you navigating the tricky waters of midlife weight gain and menopause? Ever wondered why traditional dieting methods seem to fail during this transition? Join us as we unravel the secrets of menopause weight loss with fat loss expert Dr. Bill Campbell, who has a new passion of understanding fat loss specifically in midlife women. Discover the hormonal shifts...
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The Gut–Vagina–Brain Connection: The Hidden Reason Women Lose Libido After 40 with Dr. Betsy Greenleaf
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Vaginal dryness, recurrent infections, low libido...why are we told this is “just hormones” and something we have to tolerate? In this episode, I sit down with Dr. Betsy Greenleaf, founder of the International Pause Institute, and we unpack what’s really happening down there during perimenopause and menopause. Could your symptoms be tied to your gut? Your brain? Your stress levels? We dive deep into the vaginal microbiome and why so many women struggle with yeast infections, UTIs, and painful sex—sometimes for years. Is estrogen the whole answer? Why do probiotics sometimes fail? And...
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Quick Hits: The Women's Hormone Masterclass: A Deep Dive Into Testosterone, Dutasteride, SHBG, & Menopause Weight Gain with Dr. Kyle Gillett
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Download the full episode on or on your favorite podcast platforms. In this quick hits I sit down with Dr. Gillett, to exam the complex world of women's hormones today. We'll be focusing on androgens like testosterone, DHEA, and dihydrotestosterone, and their profound impact on female health. Dr. Gillett provides insights on the role of binding globulins, hormone replacement therapy, and the interplay between insulin and androgens. We also discuss the challenges of menopausal weight gain, the benefits of GLP-1 medications for weight loss, and practical strategies anyone can use for...
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Am I in Perimenopause? How to Tell What Phase You’re In
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
If you had told me at 40 that perimenopause would turn my world upside down, I would’ve laughed. As a nutritionist specializing in women’s hormones, I thought I had it handled. So why did I gain 15 pounds, lose my sleep, and feel like a stranger in my own body? In this episode, I’m sharing what I wish someone had told me before the storm hit. Why are so many intelligent, health-conscious women still confused about where they are in perimenopause? Why are we being offered antidepressants, birth control, or told we’re “too young” instead of getting real answers? I break down the...
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Quick Hits: Navy SEAL Health Hacks: Sleep, Peptides, Psychedelics, Brain Health, and Hormones with Dr. Kirk Parsley
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. In this quick hits episode you will hear a clip from my interview with Dr. Kirk Parsley — former Navy SEAL physician and one of the leading voices in sleep optimization — to unpack what chronic sleep deprivation is really doing to your body. We dive into: Why Ambien and common sleep medications can damage long-term brain and hormonal health...
info_outlineDr. Kyle Gillett enjoys providing holistic individualized care to his patients. His practice includes preventative medicine, aesthetics, sports medicine, hormone optimization, obstetrics and infertility, integrative medicine, and precision medicine including genomics. He believes that each human is a unique creation that requires attention to their body, mind, and soul. He uses shared decision-making and an evidence-based approach. He firmly believes “food is medicine” and “exercise is medicine”. Dr. Gillett describes the “7 pillars of health”: exercise, diet, sleep, stress, social, sunlight, and spirit. These are more powerful than any medication or supplement. He enjoys spending time outdoors on the farm with his wife, two sons, and two wolfhounds.
Along with Dr. Gillett, we’re examining the complex world of women's hormones today. We’ll be focusing on androgens like testosterone, DHEA, and dihydrotestosterone, and their profound impact on female health. Dr. Gillett provides insights on the role of binding globulins, hormone replacement therapy, and the interplay between insulin and androgens. We also discuss the challenges of menopausal weight gain, the benefits of GLP-1 medications for weight loss, and practical strategies anyone can use for maintaining lean body mass.
In this episode:
- How androgens such as testosterone, DHEA, and dihydrotestosterone affect women's well-being.
- Why sex hormone binding globulin (SHBG) is critical for hormone dynamics and stability.
- Understanding the impact of thyroid binding globulin and cortisol binding globulin on hormone balance.
- How hormone replacement therapy (HRT) influences women's bodies, especially regarding androgens.
- Managing testosterone replacement therapy to avoid virilization symptoms like facial hair and voice changes.
- The role of DHT blockers in managing androgen-related conditions.
- How SHBG can be harnessed for overall hormone stability and health benefits.
- Challenges of menopausal weight gain and how hormonal changes affect body composition.
- Why integrating proper lifestyle habits is essential alongside GLP-1 medications for effective weight loss.
- How to maintain lean body mass through hormone therapy and lifestyle changes.
- How oral contraceptives and other synthetic hormones impact SHBG levels and overall hormone balance.
- The significance of SHBG levels for individuals on hormone replacement therapy or contraceptives.
- Exploring different forms of testosterone administration, including subcutaneous and intramuscular injections.
- How estrogen and progesterone influence testosterone levels through negative feedback inhibition.
- How poor sleep quality and hormonal changes contribute to menopausal weight gain.
- The paradoxical effects of hormone replacement therapy on body composition and fat gain.
- Why high SHBG must be paired with adequate hormone levels to avoid feeling unwell.
- Discussing the challenges faced when SHBG levels are artificially high due to medication.
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Karen Martel, Certified Hormone Specialist & Transformational Nutrition Coach and weight loss expert.
Visit https://karenmartel.com/