Transforming Metabolic Health and Detoxification with Sulforaphane and Berberine with David Roberts
The Hormone Solution Podcast with Karen Martel
Release Date: 06/25/2024
Goodbye 2025: A Year of Healing, Hard Truths, and Growth
The Hormone Solution Podcast with Karen Martel
It’s time to say goodbye to 2025, so let’s get real about a year that looked successful for me on the outside, but sometimes felt like a reckoning on the inside. What happens when your body forces you to slow down? And what do you do when growth starts to cost you your peace? I open up about identity shifts, burnout, and the uncomfortable realization that I couldn’t keep working the way I was. How much of my worth was tied to helping others? What happens when you’re asked to step out of the role that once defined you? I also unpack the chaos of the menopause conversation in 2025. With...
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Part 2 Q&A with Karen: Cortisol Replacement, Optimal Levels, HRT Absorption Issues, Estrogen Detox, BIEST Troches, Perimenopause Confusion & More!
The Hormone Solution Podcast with Karen Martel
This episode picks up right where part one leaves off as I dive into more of your thoughtful, honest questions in the second-part of this year-end Q&A. What happens when hormone therapy doesn’t seem to be working the way you expected? And how do you know if your dose is actually doing what you need it to do? I answer questions about achy joints, stubborn symptoms, cortisol replacement, thyroid interactions, and why some delivery methods work beautifully for one person and fail another. Why do absorption issues happen? What does “optimal” really mean when it comes to hormone levels?...
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Q&A with Karen: High Ferritin, Injectable HRT, Breakthrough Bleeding, Optimizing Hormones, Histamine Intolerance and MORE!
The Hormone Solution Podcast with Karen Martel
I’m wrapping up the year by answering your questions in this first of a two-part Q&A, and we cover a lot of ground. From confusing lab results to hormone dosing debates, I dig into the questions so many of you are quietly wondering about. What does high ferritin really mean? Is it iron—or something else entirely? We’ll also take a look at hormone replacement frustrations. Why do some people still bleed months into HRT? Are injections better than patches or creams? And how do you know if your body is actually absorbing what you’re taking? I share real-world context, common patterns...
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From Belly Fat to Brain Fog: The Top Peptides, & Hormones Helping Women in Menopause with Dr. Aleksandra Gajer
The Hormone Solution Podcast with Karen Martel
What’s really driving the sudden belly fat, brain fog, and sleep chaos so many women hit in midlife? And why do the usual “eat less, move more” solutions stop working overnight? In this episode featuring Dr. Aleksandra Gajer, we dig into the hormones and peptides that may finally explain why your body feels like it’s changing without your permission. Together, we unpack what’s happening beneath the surface (insulin resistance, inflammation, mitochondrial slowdown, hormonal roller coasters), and ask the questions women are never told to ask. What if your symptoms aren’t a lack of...
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Hair Loss, Chin Whiskers & More: How to Avoid the Not-So-Pretty Side Effects of Testosterone HRT for Women
The Hormone Solution Podcast with Karen Martel
Are you curious about the buzz surrounding testosterone therapy for women, but wondering about the side effects? In this episode, we dive deep into the world of testosterone replacement therapy’s unwanted side effects, and more importantly, how to fix them. What happens when testosterone levels spike too high? Could the very treatment meant to enhance your energy and libido lead to unwanted changes in your body? Join us as we discuss real stories from women navigating their hormone journeys and uncover the truth behind the glamorous narratives often shared on social media. Are you ready to...
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The Surprising Root Cause of the Dreaded 3 A.M. Wake-Up—And the Fix No One Told You About
The Hormone Solution Podcast with Karen Martel
Are you one of those people who wakes up at 3 A.M. and can’t fall back asleep? Have you ever wondered if there’s a deeper reason behind those late-night wake-ups? In this episode, we explore the shocking link between blood sugar fluctuations and nighttime awakenings. Blood sugar expert Dani Hamilton joins us to shed light on the root cause of these sleep disruptions. Have you ever thought about how your dietary habits could be impacting your sleep? Or how embracing fats might be the key to stable energy levels? We challenge the misconceptions around dietary fat and reveal the essential...
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The Most Asked HRT Questions of 2025 — Answered by Karen (a.k.a. The Ones She Hears 10,000 Times a Year)
The Hormone Solution Podcast with Karen Martel
Curious about the future of hormone replacement therapy (HRT) and its impact on menopause? This episode features my answers to the most common HRT questions of 2025. Can HRT be your secret weapon for a healthier, longer life, even if you aren't experiencing typical menopause symptoms? Is HRT the missing piece in your weight loss journey? Explore the fascinating link between hormone cycling and midlife wellness. What does the latest research say about personalized hormone approaches, and how might these strategies keep cardiovascular disease and osteoporosis at bay? Ever wondered about the...
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Reverse Dieting, Metabolic Recovery, and the Real Way to Fix Your Fat Loss Plateaus with Philip Pape
The Hormone Solution Podcast with Karen Martel
Are you struggling with weight loss despite following a strict diet? Ever wondered if eating more could actually help you lose weight? Join us in this episode as we dive into the intriguing world of reverse dieting and metabolic recovery with Philip Pape, a high-performance nutrition coach. Do you know about GLP-1 medications and their revolutionary role in weight management? Are you curious about how to optimize your metabolism and finally break through those frustrating weight loss plateaus? Philip unpacks these groundbreaking topics, providing you with the knowledge to transform your...
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Tesofensine: The Next Big Weight Loss Compound That Boosts Dopamine, Burns Fat and Lights up the Midlife Brain
The Hormone Solution Podcast with Karen Martel
Ready to hear about a new revolutionary weight loss strategy tailored for midlife women? Ever wondered how cutting-edge peptides and hormones can transform your wellness journey? This episode dives deep into the world of tesofensine, a fascinating compound originally researched for Parkinson's and Alzheimer's, now making waves in weight management. What makes tesofensine a potential game-changer for women experiencing hormonal shifts during perimenopause and menopause? How does it work to enhance neurotransmitter balance and boost metabolic health? Discover the unexpected benefits and...
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The Forgotten Molecule That 98% of Women Lose in Midlife—And How It Can Revive Your Libido, Energy & Glow with Cathy Eason
The Hormone Solution Podcast with Karen Martel
Curious about the molecule that's been dubbed the "molecule of energy?” Ever wonder how it impacts women's health, especially during midlife? Join us as we dive into the world of nitric oxide with Cathy Eason, Chief Science Officer at Berkeley Life. Discover why this often-overlooked molecule might be the missing piece in your health puzzle. What if your midlife vitality could be revitalized with a simple molecule? How does nitric oxide influence libido, heart health, and even skin vitality? Cathy debunks myths and uncovers the hidden connections between nitric oxide and hormones like...
info_outlineDavid Roberts holds a MPH from Johns Hopkins, a Masters in BME from the UVA, and a Bachelors in EE and BME from Duke. David has more than 20 years of public health experience on three continents. In 2014 David cofounded the gut supplement, RESTORE now Ion.
We’re welcoming David on this episode to discuss midlife wellness, focusing on how managing blood sugar and detoxification can significantly impact women navigating menopause. He examines the benefits of berberine and sulforaphane, two powerful supplements that support hormone balance and detoxification. We explore his wife’s inspiring journey in developing a stabilized sulforaphane supplement, discuss the confusion between glucoraphanin and sulforaphane, and examine how these compounds aid in detoxification, brain health, and inflammation reduction.
In this episode:
- Why insulin resistance increases without dietary changes during menopause.
- How detoxifying heavy metals and hormone byproducts is essential for midlife women.
- The benefits of berberine and sulforaphane for blood sugar regulation and detoxification.
- How sulforaphane differs from glucoraphanin and diindolylmethane.
- David’s wife’s journey from breast cancer to creating a stabilized sulforaphane supplement.
- The extensive health benefits of sulforaphane, including detoxification, brain health, and inflammation reduction.
- Why combining sulforaphane and berberine is effective in combating glyphosate’s detrimental effects.
- How sulforaphane can restore cellular detox mechanisms and improve gut barrier function.
- Why high-quality supplements are more effective and worth the investment.
- How berberine helps manage insulin resistance, cholesterol levels, and sleep quality.
- The connection between berberine and neurotransmitters like serotonin and dopamine.
- Why sulforaphane is particularly beneficial for reducing menopausal symptoms.
- The role of sulforaphane in protecting against bone loss by balancing osteoblast activity.
- How sulforaphane can reverse the suppression of NRF2 levels caused by glyphosate.
- The significance of gap junctions in communication between cells and wound healing.
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Karen Martel, Certified Hormone Specialist & Transformational Nutrition Coach and weight loss expert.
Visit https://karenmartel.com/