Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐ถโโ๏ธ๐ Just recorded a podcast on Peripheral Artery Disease (PAD) โ a silent threat affecting 200M+ people worldwide. We unpack the latest 2024 ACC/AHA guidelines: โ When to screen ๐ What therapies work ๐ฆฟ How to save limbs & lives Tune in to walk away smarter. ๐ฃ๐๏ธ #PAD #Cardiology #Guidelines #Prevention #LimbSalvage
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Just finished reviewing the latest JAMA 2025 article on osteoporosis by Morin et al. โ a must-read for anyone managing bone health in aging adults! ๐ Despite advances, 70% of fractures occur in those without DXA-defined osteoporosis. ๐ Treatment isnโt just about T-scores โ itโs about fracture risk, fall prevention, and smart sequencing of antiresorptive and anabolic therapies. ๐๏ธโโ๏ธ Plus, lifestyle matters: resistance training, calcium, vitamin D, and proactive screening save lives. ๐ Fracture Liaison Services (FLS) boost treatment initiation from 17%...
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๐จ New breakthrough in hypertension care! ๐ The Launch-HTN trial shows lorundrostat โ a selective aldosterone synthase inhibitor โ significantly lowers systolic BP in patients with uncontrolled or treatment-resistant hypertension. ๐ โ16.9 mmHg vs โ7.9 mmHg with placebo (P < .001) ๐งช Safe, well-tolerated, and effective across subgroups. A potential game-changer in aldosterone-targeted therapy! ๐๐ฅ #Hypertension #Cardiology #ClinicalTrials #PrecisionMedicine
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
Our latest podcast episode unpacks the 2025 JAMA Review on Type 2 Diabetes ๐ฌ๐ We explore: โ New diagnostic strategies โ Why GLP-1s & SGLT2is are game-changers โ How lifestyle change can lead to remission โ Individualizing A1C goals in real-world care ๐๏ธ Episode Title: โDiagnose, Personalize, Optimize: The 2025 Diabetes Blueprintโ ๐ Essential listening for clinicians, educators, and innovators in endocrine & cardiometabolic care. ๐ Tune in now and share with your network! #Type2Diabetes #CardiometabolicCare #GLP1 #SGLT2...
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How we sleep tonight shapes how we move tomorrow! ๐๐โโ๏ธ In a large-scale wearable study (๐ฑWHOOP & Fitbit data from >25,000 adults), researchers found: โ Sleeping earlier than usual boosts next-day physical activity โ Longer or later sleep = less movement ๐ฅ Max gains came from consistent sleep duration + early bedtime Letโs rethink our ๐ค to power our ๐ฅ! ๐ฃ Public health campaigns should promote sleep and exercise togetherโnot in competition. ๐ PNAS, June 2025 | doi: #SleepHealth #PhysicalActivity #WearableTech #Chronobiology...
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๐งฌ Curious why we age? ๐ฐ๏ธ From DNA damage to developmental programs gone rogue, this new podcast episode dives deep into 17 theories of ageing โ some classic, some controversial. ๐ We explore wear-and-tear, free radicals, telomeres, mitochondria, stem cell exhaustion, and the rising stars of epigenetic drift and hyperfunction theory. ๐๏ธ Whether youโre a scientist, clinician, or just fascinated by the biology of time, tune in to uncover what really drives the ageing processโand what might one day slow it down. ๐ง Listen now: โWrinkle, Rust, and...
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Refractory Angina: Time to Rethink the Diagnosis ๐ซ๐ฅ Chest pain that defies stents and statins? It may not be your typical obstructive CAD. This podcast unpacks the redefinition of refractory angina โ spotlighting INOCA, CMD, vasospasm, and myocardial bridging ๐ฌโ๏ธ We explore PET, CMR, CFVR, and wire-based diagnostics ๐ โ and why a multidisciplinary Angina Heart Team is key to transforming care ๐ฉโโ๏ธ๐จโโ๏ธ๐ง ๐ง Listen in as we chart a course from frustration to precision โ because even stubborn angina has a story and a solution. ...
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๐ฌ๐ New insights from Nature Aging: Inflammaging isnโt universal! A fascinating cross-cultural study comparing Italy ๐ฎ๐น, Singapore ๐ธ๐ฌ, Bolivia ๐ง๐ด, and Malaysia ๐ฒ๐พ shows that age-related inflammationโlong considered a hallmark of agingโmay actually be a product of industrialized environments. Populations like the Tsimane (Bolivia) and Orang Asli (Malaysian), despite high infection loads, show minimal correlation between cytokines and age-related disease. ๐ Conclusion: Inflammaging is not destinyโitโs context. ๐งช Read the...
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๐จ AI vs Sudden Cardiac Death in HCM ๐ซ๐ค Exciting new study published in Nature Cardiovascular Research showcases MAARS, a multimodal AI model that dramatically improves risk prediction for sudden arrhythmic death in hypertrophic cardiomyopathy patients. ๐ MAARS outperformed current guidelines with AUROC of 0.89 (internal) and 0.81 (external) ๐ง Integrated data: LGE-CMR ๐งฒ, EHR ๐, and echo/CMR reports ๐ป โ๏ธ Demonstrated fairness across age and sex subgroups ๐ Transparent predictions via Shapley values and attention heatmaps A leap toward...
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โVax to the Future: Cancer Immunity Revolution ๐งฌ๐โ Cancer vaccines are no longer a promise โ theyโre a precision revolution. From HBV and HPV to cutting-edge mRNA-based neoantigen vaccines, we explore how tumor sequencing + AI + immune checkpoint inhibitors are reshaping oncology. ๐ Real data from trials in melanoma, ccRCC, and pancreatic cancer โ๏ธ PD-1 inhibitors meet targeted T cells ๐ A safer, scalable future for cancer care ๐ง Tune in to Got Knowledge Doc as we decode this game-changing viewpoint from JCI โ โVaccines in Cancer Treatment...
info_outlineVitamin B12: Essential for Health ๐ฉธ๐ง
Vitamin B12 is crucial for red blood cell formation, brain function, and DNA synthesis.
Found in animal-based foods ๐ฅ๐ณ๐, those on vegan diets need fortified foods or supplements ๐.
Deficiency can cause anemia, neurological issues, and cognitive decline โ ๏ธ.
High-risk groups include vegans, vegetarians, older adults, and individuals with malabsorption conditions ๐ฅ.
Maternal deficiency affects fetal development ๐คฐ๐ถ.
Absorption declines with age, and severe cases (e.g., pernicious anemia) may require high-dose supplements or injections ๐.
Research on its role in preventing cognitive decline remains inconclusive ๐ค.