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🧬 Silencing Risk: Lepodisiran vs Lp(a) show art 🧬 Silencing Risk: Lepodisiran vs Lp(a)

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New hope for high Lp(a)! πŸ’‰ Lepodisiran, a long-acting siRNA, slashed Lp(a) by 94% with just 2 shots/year. πŸ”¬ RNA precision meets cardiac prevention. πŸ“‰ Silent killer, silenced. #CardioTwitter #RNAtherapy #LipoproteinA

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πŸ’¨ Breathing Battles: Navigating COPD Phenotypes show art πŸ’¨ Breathing Battles: Navigating COPD Phenotypes

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

πŸŒ¬οΈπŸšΆβ€β™‚οΈ COPD comes in many forms! From chronic bronchitis πŸͺ« to emphysema πŸ’¨, frequent exacerbators 🚨, asthma-COPD overlap πŸŒͺ️, and eosinophilic type 🧫. Tailoring treatment to phenotype is key! #COPD #PrecisionMedicine #RespiratoryCare

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πŸ’Š TANDEM Triumph: Dual Power for LDL Cholesterol Reduction! show art πŸ’Š TANDEM Triumph: Dual Power for LDL Cholesterol Reduction!

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

πŸš€ TANDEM Trial: Combining Obicetrapib & Ezetimibe for a powerful LDL reduction! πŸ’Š βœ… -48.6% vs placebo, -27.9% vs Ezetimibe, -16.8% vs Obicetrapib πŸ’ͺ Safe, effective, and oral! #Cardiology #LipidManagement #ASCVD

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Fungal Pharmacists, Fatty Liver, Future Frontiers πŸ§¬πŸ©ΈπŸ„ show art Fungal Pharmacists, Fatty Liver, Future Frontiers πŸ§¬πŸ©ΈπŸ„

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

A gut fungus πŸ„ (Fusarium foetens) secretes FF-C1 πŸ§ͺ, a metabolite that inhibits CerS6 and lowers ceramides πŸ©Έβ€”shielding mice from MASH πŸ›‘οΈ. Fungi aren’t just freeloadersβ€”they may be our next therapeutic allies! πŸ’ŠπŸ§  #Microbiome #LiverHealth #FungalTherapy #Science

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πŸ’ͺ Powerful Cholesterol Control: Obicetrapib in the Spotlight 🌟 show art πŸ’ͺ Powerful Cholesterol Control: Obicetrapib in the Spotlight 🌟

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

πŸš€ Obicetrapib: A Breakthrough in LDL Lowering! πŸ“‰ Reduced LDL by 29.9% in high-risk patients (p<0.001) πŸ’‘ Promising adjunct to lipid-lowering therapy! #Cardiology #LipidManagement #HeartHealth πŸ’“

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Fat Chance! πŸ”¬πŸ§¬ Middle-Age Spread Starts at the Cellular Level show art Fat Chance! πŸ”¬πŸ§¬ Middle-Age Spread Starts at the Cellular Level

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Here’s a tweet with emojis based on the article:   🧬 Middle-age spread decoded! πŸ•°οΈ Visceral fat grows in midlife not from bigger cellsβ€”but new ones! 🎯 CP-A cells fire up fat formation via LIFR–STAT3 πŸ”₯ πŸ’Š Targeting them may halt metabolic disease before it starts. #Aging #Obesity #CellBiology #Metabolism 🧫   Would you like a version with a more humorous tone or one tailored for clinicians?

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πŸ”πŸ“ŠπŸ›‘οΈ Detect, Decode, Defend: A New Era in Coronary Risk Prediction show art πŸ”πŸ“ŠπŸ›‘οΈ Detect, Decode, Defend: A New Era in Coronary Risk Prediction

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New era in heart disease prediction! 🧬 + πŸ§ͺ + πŸ€– = Meta-prediction model that beats PCE & QRISK3 πŸ“ˆ Detects hidden CAD risk in young, women & β€œlow-risk” groups 🎯 Precision prevention just got personal. πŸ«€ Published in Nature Medicine #CardioTwitter #AI #Genomics #CAD

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Dr RR Baliga's Philosophical Discourses: Epicurus (Greece, 341–270 BCE) – Founder of Epicureanism show art Dr RR Baliga's Philosophical Discourses: Epicurus (Greece, 341–270 BCE) – Founder of Epicureanism

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Epicurus (341–270 BC) was an ancient Greek philosopher who founded Epicureanism, emphasizing the pursuit of a tranquil, happy life through ataraxia (freedom from fear) and aponia (absence of pain). His teachings combined atomism, ethics, and naturalistic theology, advocating simple living, friendship, and the rejection of superstition.

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Calcium Wars: Orbital Atherectomy vs. Balloon Angioplasty β€” The ECLIPSE Verdict βš”οΈπŸ§ πŸ’” show art Calcium Wars: Orbital Atherectomy vs. Balloon Angioplasty β€” The ECLIPSE Verdict βš”οΈπŸ§ πŸ’”

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨ECLIPSE Trial Results🚨 Orbital atherectomy πŸŒ€ vs. balloon angioplasty 🎈 before stenting in severe coronary calcification πŸ’” 🎯 No added benefit with atherectomy 🧠 Balloon-first + imaging = smart strategy πŸ“Š Lancet 2025 | #CardioTwitter #InterventionalCardiology #ECLIPSETrial

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Genes 🧬, Journeys 🌍, and Hidden Hazards ⚑: Unlocking Health with Exposomics show art Genes 🧬, Journeys 🌍, and Hidden Hazards ⚑: Unlocking Health with Exposomics

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

  β€œYour DNA 🧬 is just half the story β€” your exposome 🌍 writes the rest! From air 🌫️ to food 🍎 to stress 😰, exposomics unlocks the hidden drivers of health πŸ”πŸ’₯. Predict. Prevent. Prosper. πŸš€ #Exposomics #PrecisionMedicine”

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The SOUL trial πŸ§ͺ showed that oral semaglutide πŸ’Š significantly reduced major cardiovascular events ❀️ (MACE) in people with type 2 diabetes 🩸 and ASCVD/CKD πŸš‘.

 

Over ~4 years, it cut heart attacks πŸ’₯, lowered HbA1c πŸ“‰, reduced weight βš–οΈ, and inflammation πŸ”₯ β€” all with a once-daily pill πŸ•ŠοΈ and no rise in serious side effects.