When to Start HRT: A Woman’s Guide to Aging Well and Reaping the Benefits of Hormones
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Release Date: 04/05/2025
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Dr. Anshul Gupta is a best-selling author, speaker, researcher, and leading expert in Hashimoto’s disease. Through his work, he helps people better understand the root causes of Hashimoto’s and how a functional medicine approach may help improve thyroid function, reduce symptoms, and address the autoimmune process. Hashimoto’s is one of the...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
What do you do when you finally start HRT and instead of feeling amazing, you feel exhausted, puffy, bloated, or like something is just not right? Or you start a GLP-1, lose weight, and suddenly your hair starts falling out? Today’s episode is another listener Q&A, and we are getting into the real-life questions women are asking when hormone therapy, thyroid treatment, weight-loss peptides, and menopause symptoms do not fit neatly into a textbook. We talk about progesterone intolerance, oral versus topical progesterone, when estradiol may still be too low even though your doctor says...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. This week we're tackling the misconceptions around health and weight loss, and exploring sustainable ways to achieve wellness goals. I'll tell you some practical tips to debunk dieting and exercise myths, and emphasize the importance of positive thinking while addressing the danger of self-sabotage. It's time to face your own excuses, adopt...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
You cannot open your phone anymore without hearing about Ozempic, Wegovy, Mounjaro, Zepbound, retatrutide, and before-and-after transformations. One person says GLP-1s are the greatest thing ever. Another says they are going to destroy your health. As usual, the truth is somewhere in the middle. In this episode, I break down GLP-1s specifically through the lens of perimenopause and menopause, because midlife women are dealing with a completely different metabolic landscape. Estrogen is changing. Muscle is easier to lose. Insulin sensitivity may be shifting. Sleep is falling apart. Belly fat is...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
If you are taking HRT, it is not enough to only ask how much estrogen you are using. You also have to ask a second question: how well is your body actually processing and clearing that estrogen? In this episode, I sit down with David Roberts and John Gilday from Mara Labs to unpack estrogen metabolism, estrogen receptors, environmental hormone disruptors, detoxification pathways, and why the conversation around “estrogen dominance” is often way too simplistic. We talk about the difference between having high estrogen and having estrogen that is not being metabolized efficiently, especially...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Have you ever felt like you are doing everything right and your body is just not cooperating? You are eating well, exercising, tracking your protein, fasting, taking supplements, getting your steps in, and still gaining weight, feeling exhausted, sleeping poorly, and wondering why the strategies that used to work suddenly do not anymore. In this episode, I sit down with Debbie Potts to talk about what may actually be happening when healthy habits become unhealthy stressors. We get into the connection between the nervous system, metabolism, hormones, muscle, recovery, under-fueling,...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Angela is an award-winning Nutritionist, Health & Performance Coach, Keynote Speaker and Host of The High Performance Health Podcast. A former corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela regularly gives keynotes to large fitness, health and wellness events She also delivers Health...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
How do you know if your HRT is actually optimized? Not just enough to stop a hot flash, but enough to support your bones, brain, mood, metabolism, sleep, sexual health, and overall quality of life? In this episode, I break down one of the most confusing parts of hormone replacement therapy: dose, levels, and symptom response. Because the old-school advice to simply use the lowest dose possible until your symptoms disappear does not tell us the whole story. At the same time, more is absolutely not always better. We dig into what the research actually tells us about estradiol dose and brain...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. What actually works when it comes to anti-aging skincare, and what is simply expensive marketing in a very attractive bottle? In this quick hits clip Karen sits down with Amitay Eshel, co-founder and CEO of Young Goose. Amitay explains why effective anti-aging skincare is about much more than moisturizing the surface of the skin. Healthy,...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Something happened after my conversation with Natalie Jill on her podcast, Midlife Conversations. Women flooded my inbox and my community, not with questions about dosing or side effects, but with something closer to relief. They finally felt heard. That reaction told me this conversation needed a second chapter, so I'm bringing you the rest of it here, along with some of the raw, honest messages from women in my community who are done being quietly shamed for a choice that has changed their health and their lives. In this episode, Natalie and I go back to where it all started. We talk about...
info_outlineHave you ever wondered what the four phases of hormonal loss are and why they matter as you age?
How can progesterone help manage symptoms without messing with your estrogen levels?
Why is it so important to test your progesterone levels, even if your cycles are irregular?
Did you know that thyroid and testosterone medications can impact your natural hormone production?
Why is it crucial to stick to physiological doses of thyroid and testosterone for long-term health?
How can early intervention with progesterone actually help protect your breasts?
What’s the real significance of the uterus beyond childbearing, and what happens if you’ve had a hysterectomy?
How does estradiol, a key form of estrogen, play a crucial role in maintaining long-term health?
Are birth control pills the best option when you need estrogen, or is there a better alternative?
How can estradiol help you maintain bone density, cognitive function, and overall well-being?
Why do we need to challenge the fear-based narrative around estrogen and understand its true benefits?
Have you considered how over-the-counter hormone creams might offer an accessible and effective solution?
Could your genetics be affecting how severe your hormonal symptoms are during menopause?
Why can progesterone loss lead to uncomfortable symptoms like heavy periods and even thyroid issues?
What is progesterone cycling, and how does it help balance hormones without disrupting estrogen production?
How do stress, trauma, and dietary habits play a role in when menopause starts?
Why is understanding hormonal feedback loops essential for effective medication and hormone therapy?
Why should you be proactive and really listen to your body when it comes to HRT decisions?
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Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.
Visit karenmartel.com to explore our comprehensive programs:
- Bioidentical Hormone Replacement Therapy
- Individualized Weight Loss Programs
- Peptide Therapy for weight loss
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Your host:
Karen Martel
Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert