π§ Clearing the mind: How Glymphatics & Lymphatics Clear the Mind
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π§ π‘ New Insights! The brain isnβt as βimmune privilegedβ as once thought! ππ Glymphatics & meningeal lymphatics reveal how the CNS clears waste & connects to immunity. π¦ Aging & neurodegeneration challenge this balance. #Neuroscience #Immunology #BrainHealth π§¬π
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TR Troubles π: Progress, Pitfalls, and Patient Selection
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π¦ Tricuspid Regurgitation (TR) Troubles! π Despite promising interventions, recent trials show no survival benefit. Patient selection & procedural success are key! π Focus on quality of life, not just longevity. #Cardiology #HeartHealth #TRManagement π
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Food as Medicine: Unleashing the Hidden Therapeutic Power of Nutrition Dark Matter π±π
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π±π Unlocking the Power of Food! #NutritionDarkMatter holds 139,000+ molecules with therapeutic potential. π AI-driven research is paving the way for #PrecisionNutrition & innovative healthcare solutions! π #FoodAsMedicine #HealthRevolution π
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π§ Stents vs Scalpels: The FAME 3 Face-Off π©ΊβοΈ
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π¨ FAME 3 at 5 years: FFR-guided PCI π οΈ vs CABG π« in 3-vessel CAD β no difference in death/stroke, but more MI & revascularization with PCI β οΈ. Heart team matters π€. #CardioTwitter #FAME3 #Revascularization π©Ίπ
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Dr RR Baliga's Philosophical Discourses: Zeno of Citium (Greece, c. 334β262 BCE) β Founder of Stoicism
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Zeno of Citium (c. 334 β c. 262 BC) was a Hellenistic philosopher from Cyprus and the founder of Stoicism. His philosophy emphasized living in harmony with nature and practicing virtue to attain peace of mind (ataraxia). Zenoβs teachings influenced ethics, logic, and natural philosophy, laying the foundation for Stoicismβs prominence during the Roman era and beyond. Despite losing his original writings, Zenoβs ideas survived through the works of later Stoics like Cleanthes and Chrysippus.
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π« Flow vs Form π οΈ: Guiding PCI with FFR or IVUS in the FLAVOUR II Trial π―
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π¨ New from #FLAVOURII: Angio-FFR vs IVUS to guide PCI π« π― Similar outcomes π Fewer stents π§ Smarter decisions Is flow-based guidance the future? π #CardioTwitter #FFR #IVUS #Intervention π° Lancet 2025 | π RCT | π¨π³ 1839 patients
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π Next-Gen Weight Loss: Tirzepatideβs Winning Edge Over Semaglutide
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π Tirzepatide Triumphs! πͺ In a head-to-head trial, #Tirzepatide led to greater weight loss (-20.2%) compared to #Semaglutide (-13.7%) over 72 weeks! ππ Superior waist reduction too! #ObesityManagement #WeightLoss #GLP1 #GIP π©Ίπ #CardiometabolicHealth #ClinicalResearch
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Head Hits, Heart Risks: Concussions in Football Spike Cardiovascular Danger πβ€οΈ
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ππ₯ Concussions in football donβt just hit the brainβthey impact the heart too! ππ« New study shows increased BP, arterial stiffness, and cardiac risks in NCAA athletes post-concussion. π§ β‘οΈβ€οΈ #Cardiology #SportsMedicine #ConcussionRisk #HeartHealth
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π¦ Microbes, Mutations, and Malignancy: Unveiling the GutβBlood Cancer Axis π
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𧬠A molecule from aging gut bacteriaβADP-heptoseβenters the bloodstream, activates ALPK1, and triggers NF-ΞΊB signaling, driving the expansion of mutant blood stem cells. π¦ π§ This discovery links gut health to leukemia risk and reveals new targets like ALPK1 and UBE2N for cancer prevention. π₯π©Έ
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Lower Blood Pressure, Sharper Minds, Less Dementia, Longer Lives π§ ππΎ
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π§ Big win for brains & blood pressure! In a massive rural China trial (n=33,995), lowering BP with non-physician care β dementia risk by 15%! A scalable, lifesaving model for LMICs. πΎππ #Dementia #Hypertension #GlobalHealth
info_outlineColchicine π, once a humble gout remedy, is now reshaping coronary care π«. Trials show it reduces events in stable CAD β , but its benefit post-MI βοΈ depends on timing β°. Inflammation matters β and so does when we strike.
Colchicine in CAD: Small Pill, Big Debate ππ₯π«
An ancient anti-inflammatory has found new life in cardiology β reducing heart attacks when started late, but disappointing when given early after an MI.
Bottom Line: Timing matters. Too soon, and it fizzles. Wait until the fire cools, and colchicine shines. β°β¨