💪 Immunotherapy Power Duo: Nivolumab + Ipilimumab vs. TKIs in HCC
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚀 New Breakthrough in Liver Cancer! 🌟 The CheckMate 9DW trial shows that Nivolumab + Ipilimumab significantly improves survival in unresectable #HCC compared to lenvatinib/sorafenib! 🧬💪 #Immunotherapy #CancerResearch #LiverCancer #Oncology 💉
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💔 AF, Ablation, and Brain Clean-Up by Glymphatics: Fact or Fiction?
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧠💔 Atrial Fibrillation (AF) disrupts brain glymphatic function, leading to cognitive decline! 😓 Catheter ablation may help restore rhythm and brain clearance. More research needed! 📊 #Cardiology #BrainHealth #AF #Cognition 💡
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🧠 Clearing the mind: How Glymphatics & Lymphatics Clear the Mind
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧠💡 New Insights! The brain isn’t as “immune privileged” as once thought! 🌊🔄 Glymphatics & meningeal lymphatics reveal how the CNS clears waste & connects to immunity. 🦠 Aging & neurodegeneration challenge this balance. #Neuroscience #Immunology #BrainHealth 🧬🚀
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TR Troubles 🌟: Progress, Pitfalls, and Patient Selection
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚦 Tricuspid Regurgitation (TR) Troubles! 💔 Despite promising interventions, recent trials show no survival benefit. Patient selection & procedural success are key! 📝 Focus on quality of life, not just longevity. #Cardiology #HeartHealth #TRManagement 💙
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Food as Medicine: Unleashing the Hidden Therapeutic Power of Nutrition Dark Matter 🌱💊
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🌱💊 Unlocking the Power of Food! #NutritionDarkMatter holds 139,000+ molecules with therapeutic potential. 🍎 AI-driven research is paving the way for #PrecisionNutrition & innovative healthcare solutions! 🌟 #FoodAsMedicine #HealthRevolution 🚀
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🚧 Stents vs Scalpels: The FAME 3 Face-Off 🩺⚔️
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚨 FAME 3 at 5 years: FFR-guided PCI 🛠️ vs CABG 🫀 in 3-vessel CAD — no difference in death/stroke, but more MI & revascularization with PCI ⚠️. Heart team matters 🤝. #CardioTwitter #FAME3 #Revascularization 🩺📊
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Dr RR Baliga's Philosophical Discourses: Zeno of Citium (Greece, c. 334–262 BCE) – Founder of Stoicism
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Zeno of Citium (c. 334 – c. 262 BC) was a Hellenistic philosopher from Cyprus and the founder of Stoicism. His philosophy emphasized living in harmony with nature and practicing virtue to attain peace of mind (ataraxia). Zeno’s teachings influenced ethics, logic, and natural philosophy, laying the foundation for Stoicism’s prominence during the Roman era and beyond. Despite losing his original writings, Zeno’s ideas survived through the works of later Stoics like Cleanthes and Chrysippus.
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🫀 Flow vs Form 🛠️: Guiding PCI with FFR or IVUS in the FLAVOUR II Trial 🎯
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚨 New from #FLAVOURII: Angio-FFR vs IVUS to guide PCI 🫀 🎯 Similar outcomes 📉 Fewer stents 🧠 Smarter decisions Is flow-based guidance the future? 🌍 #CardioTwitter #FFR #IVUS #Intervention 📰 Lancet 2025 | 📊 RCT | 🇨🇳 1839 patients
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🚀 Next-Gen Weight Loss: Tirzepatide’s Winning Edge Over Semaglutide
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚀 Tirzepatide Triumphs! 💪 In a head-to-head trial, #Tirzepatide led to greater weight loss (-20.2%) compared to #Semaglutide (-13.7%) over 72 weeks! 📉🌟 Superior waist reduction too! #ObesityManagement #WeightLoss #GLP1 #GIP 🩺💊 #CardiometabolicHealth #ClinicalResearch
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Head Hits, Heart Risks: Concussions in Football Spike Cardiovascular Danger 🏈❤️
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🏈💥 Concussions in football don’t just hit the brain—they impact the heart too! 📈🫀 New study shows increased BP, arterial stiffness, and cardiac risks in NCAA athletes post-concussion. 🧠➡️❤️ #Cardiology #SportsMedicine #ConcussionRisk #HeartHealth
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❄️ Conceived in the Cold? Individuals conceived during colder months show higher brown fat activity, increased thermogenesis, and lower BMI as adults.
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🔬 Using PET/CT, NIR-TRS, and doubly labeled water (DLW), the study linked preconception cold exposure to greater energy expenditure and reduced visceral fat.
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🧬 The key factor: Temperature and its diurnal variation before conception — not birth season — predicts adult brown adipose tissue (BAT) function.
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📉 Cold-induced BAT activation leads to better cold adaptation, improved CIT, DIT, and total energy expenditure (TEE) — even years later.
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🧠 Researchers propose PfOHaD (Pre-fertilization Origins of Health and Disease) — expanding DOHaD to include paternal cold exposure as a metabolic epigenetic switch.