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π New Breakthrough in Liver Cancer! π The CheckMate 9DW trial shows that Nivolumab + Ipilimumab significantly improves survival in unresectable #HCC compared to lenvatinib/sorafenib! π§¬πͺ #Immunotherapy #CancerResearch #LiverCancer #Oncology π
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π§ π Atrial Fibrillation (AF) disrupts brain glymphatic function, leading to cognitive decline! π Catheter ablation may help restore rhythm and brain clearance. More research needed! π #Cardiology #BrainHealth #AF #Cognition π‘
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π§ π‘ New Insights! The brain isnβt as βimmune privilegedβ as once thought! ππ Glymphatics & meningeal lymphatics reveal how the CNS clears waste & connects to immunity. π¦ Aging & neurodegeneration challenge this balance. #Neuroscience #Immunology #BrainHealth π§¬π
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π¦ Tricuspid Regurgitation (TR) Troubles! π Despite promising interventions, recent trials show no survival benefit. Patient selection & procedural success are key! π Focus on quality of life, not just longevity. #Cardiology #HeartHealth #TRManagement π
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π±π Unlocking the Power of Food! #NutritionDarkMatter holds 139,000+ molecules with therapeutic potential. π AI-driven research is paving the way for #PrecisionNutrition & innovative healthcare solutions! π #FoodAsMedicine #HealthRevolution π
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π¨ FAME 3 at 5 years: FFR-guided PCI π οΈ vs CABG π« in 3-vessel CAD β no difference in death/stroke, but more MI & revascularization with PCI β οΈ. Heart team matters π€. #CardioTwitter #FAME3 #Revascularization π©Ίπ
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Zeno of Citium (c. 334 β c. 262 BC) was a Hellenistic philosopher from Cyprus and the founder of Stoicism. His philosophy emphasized living in harmony with nature and practicing virtue to attain peace of mind (ataraxia). Zenoβs teachings influenced ethics, logic, and natural philosophy, laying the foundation for Stoicismβs prominence during the Roman era and beyond. Despite losing his original writings, Zenoβs ideas survived through the works of later Stoics like Cleanthes and Chrysippus.
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π¨ New from #FLAVOURII: Angio-FFR vs IVUS to guide PCI π« π― Similar outcomes π Fewer stents π§ Smarter decisions Is flow-based guidance the future? π #CardioTwitter #FFR #IVUS #Intervention π° Lancet 2025 | π RCT | π¨π³ 1839 patients
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π Tirzepatide Triumphs! πͺ In a head-to-head trial, #Tirzepatide led to greater weight loss (-20.2%) compared to #Semaglutide (-13.7%) over 72 weeks! ππ Superior waist reduction too! #ObesityManagement #WeightLoss #GLP1 #GIP π©Ίπ #CardiometabolicHealth #ClinicalResearch
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ππ₯ Concussions in football donβt just hit the brainβthey impact the heart too! ππ« New study shows increased BP, arterial stiffness, and cardiac risks in NCAA athletes post-concussion. π§ β‘οΈβ€οΈ #Cardiology #SportsMedicine #ConcussionRisk #HeartHealth
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βοΈ Conceived in the Cold? Individuals conceived during colder months show higher brown fat activity, increased thermogenesis, and lower BMI as adults.
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π¬ Using PET/CT, NIR-TRS, and doubly labeled water (DLW), the study linked preconception cold exposure to greater energy expenditure and reduced visceral fat.
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𧬠The key factor: Temperature and its diurnal variation before conception β not birth season β predicts adult brown adipose tissue (BAT) function.
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π Cold-induced BAT activation leads to better cold adaptation, improved CIT, DIT, and total energy expenditure (TEE) β even years later.
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π§ Researchers propose PfOHaD (Pre-fertilization Origins of Health and Disease) β expanding DOHaD to include paternal cold exposure as a metabolic epigenetic switch.