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π« Post-op AFib? Blame IL-6! New @JClinInvest study shows IL-6 β‘οΈ STAT3 β‘οΈ CaMKII β‘οΈ RyR2 leak triggers post-op AFib. 𧬠Macrophage IL-6RΞ± is the match. π§― TTI-101 & KN-93 douse the flame. β‘ Targeting IL-6 signaling = future Rx? #CardioTwitter #AFib #Inflammation #JCI
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π₯¦π Want to age like fine wine? Choose high-quality carbs! In a 32-year study of 47K women, fiber-rich carbs (from πΎ, π₯, π±) boosted odds of healthy aging π§ πͺπ§ββοΈ Refined carbs? Not so kind. #HealthyAging #NutritionMatters #WomensHealth π§¬ππ
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π§ π«π§« New study in Nature Medicine shows that multiorgan MRI predicts both π cardiovascular and π©Έ liver events. Cardiac (LVEF β€50%) + Liver (cT1 β₯800ms) = π¨ higher risk & earlier events. Integrated imaging = smarter prevention! ππ #Cardiology #Hepatology #MRI #MASLD #CVD
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π New Breakthrough in Liver Cancer! π The CheckMate 9DW trial shows that Nivolumab + Ipilimumab significantly improves survival in unresectable #HCC compared to lenvatinib/sorafenib! π§¬πͺ #Immunotherapy #CancerResearch #LiverCancer #Oncology π
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π§ π Atrial Fibrillation (AF) disrupts brain glymphatic function, leading to cognitive decline! π Catheter ablation may help restore rhythm and brain clearance. More research needed! π #Cardiology #BrainHealth #AF #Cognition π‘
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π§ π‘ New Insights! The brain isnβt as βimmune privilegedβ as once thought! ππ Glymphatics & meningeal lymphatics reveal how the CNS clears waste & connects to immunity. π¦ Aging & neurodegeneration challenge this balance. #Neuroscience #Immunology #BrainHealth π§¬π
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π¦ Tricuspid Regurgitation (TR) Troubles! π Despite promising interventions, recent trials show no survival benefit. Patient selection & procedural success are key! π Focus on quality of life, not just longevity. #Cardiology #HeartHealth #TRManagement π
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π±π Unlocking the Power of Food! #NutritionDarkMatter holds 139,000+ molecules with therapeutic potential. π AI-driven research is paving the way for #PrecisionNutrition & innovative healthcare solutions! π #FoodAsMedicine #HealthRevolution π
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π¨ FAME 3 at 5 years: FFR-guided PCI π οΈ vs CABG π« in 3-vessel CAD β no difference in death/stroke, but more MI & revascularization with PCI β οΈ. Heart team matters π€. #CardioTwitter #FAME3 #Revascularization π©Ίπ
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Zeno of Citium (c. 334 β c. 262 BC) was a Hellenistic philosopher from Cyprus and the founder of Stoicism. His philosophy emphasized living in harmony with nature and practicing virtue to attain peace of mind (ataraxia). Zenoβs teachings influenced ethics, logic, and natural philosophy, laying the foundation for Stoicismβs prominence during the Roman era and beyond. Despite losing his original writings, Zenoβs ideas survived through the works of later Stoics like Cleanthes and Chrysippus.
info_outlineπ§ͺ SMART-CHOICE 3 in a Nutshell
π£ Clopidogrel beat π aspirin post-PCI:
π Fewer MACCE (4.4% vs 6.6%)
π©Έ Same bleeding risk
π½οΈ Fewer GI events
β οΈ Editorial: Fragile stats, late benefit, open questions on lifelong therapy.
π― Verdict: Promisingβbut not bulletproof.