Triglycerides, Trials, and Triumph π§ππ: The ANGPTL4 Story
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π¨ New frontier in lipid-lowering! 𧬠Blocking ANGPTL4 with MAR001 slashed triglycerides & remnant cholesterol by >50% π‘οΈ Safe, well-tolerated, no lymph node issues π‘ Promising for residual ASCVD risk Next step? Big trials, big answers! ππ« #LipidScience #CardioTwitter #PrecisionMedicine
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Cracking the Code of Short Sleepers π§ ππ΄
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Why do some people sleep just 4 hours and feel great? π΄πͺ A new study links the 𧬠SIK3-N783Y mutation to natural short sleep! Less sleep, more delta power π§ β‘ ππ #SleepScience #Genetics #SIK3 #ShortSleepers
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π₯ IL-6, Inflammation, and Irregular Beats: The Cytokine Cascade Driving Post-Op AFib
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π« Post-op AFib? Blame IL-6! New @JClinInvest study shows IL-6 β‘οΈ STAT3 β‘οΈ CaMKII β‘οΈ RyR2 leak triggers post-op AFib. 𧬠Macrophage IL-6RΞ± is the match. π§― TTI-101 & KN-93 douse the flame. β‘ Targeting IL-6 signaling = future Rx? #CardioTwitter #AFib #Inflammation #JCI
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Good Carbs, Great Life, Golden Years π₯¦β¨π΅
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π₯¦π Want to age like fine wine? Choose high-quality carbs! In a 32-year study of 47K women, fiber-rich carbs (from πΎ, π₯, π±) boosted odds of healthy aging π§ πͺπ§ββοΈ Refined carbs? Not so kind. #HealthyAging #NutritionMatters #WomensHealth π§¬ππ
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MRI Matters π§²: Imaging the Silent Duo β Heart & Liver π«
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π§ π«π§« New study in Nature Medicine shows that multiorgan MRI predicts both π cardiovascular and π©Έ liver events. Cardiac (LVEF β€50%) + Liver (cT1 β₯800ms) = π¨ higher risk & earlier events. Integrated imaging = smarter prevention! ππ #Cardiology #Hepatology #MRI #MASLD #CVD
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πͺ Immunotherapy Power Duo: Nivolumab + Ipilimumab vs. TKIs in HCC
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π New Breakthrough in Liver Cancer! π The CheckMate 9DW trial shows that Nivolumab + Ipilimumab significantly improves survival in unresectable #HCC compared to lenvatinib/sorafenib! π§¬πͺ #Immunotherapy #CancerResearch #LiverCancer #Oncology π
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π AF, Ablation, and Brain Clean-Up by Glymphatics: Fact or Fiction?
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π§ π Atrial Fibrillation (AF) disrupts brain glymphatic function, leading to cognitive decline! π Catheter ablation may help restore rhythm and brain clearance. More research needed! π #Cardiology #BrainHealth #AF #Cognition π‘
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π§ Clearing the mind: How Glymphatics & Lymphatics Clear the Mind
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π§ π‘ New Insights! The brain isnβt as βimmune privilegedβ as once thought! ππ Glymphatics & meningeal lymphatics reveal how the CNS clears waste & connects to immunity. π¦ Aging & neurodegeneration challenge this balance. #Neuroscience #Immunology #BrainHealth π§¬π
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TR Troubles π: Progress, Pitfalls, and Patient Selection
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π¦ Tricuspid Regurgitation (TR) Troubles! π Despite promising interventions, recent trials show no survival benefit. Patient selection & procedural success are key! π Focus on quality of life, not just longevity. #Cardiology #HeartHealth #TRManagement π
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Food as Medicine: Unleashing the Hidden Therapeutic Power of Nutrition Dark Matter π±π
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π±π Unlocking the Power of Food! #NutritionDarkMatter holds 139,000+ molecules with therapeutic potential. π AI-driven research is paving the way for #PrecisionNutrition & innovative healthcare solutions! π #FoodAsMedicine #HealthRevolution π
info_outline𧴠Delgocitinib cream outperformed oral alitretinoin in treating severe chronic hand eczema over 24 weeks.
π Greater reduction in HECSI, π better quality of life, and β οΈ fewer side effects make it a promising non-steroidal alternative.
π Time to rethink systemic pills β topical wins hands down! ποΈβ