👄 Mouths Heal Better: What Your Skin Can Learn from Oral Wounds
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Exciting new insights from Science Translational Medicine (2025)! Researchers uncovered how the GAS6–AXL–FAK axis determines whether wounds heal with scars or regeneration. 🧬💉 💡 Activating AXL with GAS6 rewires fibrotic healing into scarless repair — especially in the oral mucosa. 💥 Blocking AXL flips the script, leading to fibrosis even in normally regenerative tissues. This could revolutionize how we approach scar prevention and tissue regeneration. 🩹✨ #RegenerativeMedicine #WoundHealing #Fibrosis #AXL #FAK #PrecisionMedicine #GAS6 #scRNAseq...
info_outline
☕ Evidence Per Cup: Coffee and Cardiovascular Outcomes
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
☕💓 Is your daily brew helping or harming your heart? New evidence from a comprehensive European Heart Journal review suggests that moderate coffee consumption (1–4 cups/day) is linked to reduced risks of hypertension, type 2 diabetes, coronary artery disease, heart failure, stroke, and even mortality. 🧬 Benefits often persist regardless of caffeine content, and filtered coffee appears safest for lipid profiles. ⚠️ But beware: excessive intake and unfiltered brews may raise LDL. 📊 Great read for clinicians navigating patient questions on coffee and...
info_outline
Longevity’s Guardians?: The Brain and Immune System Duo
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧠🧬 New research alert! Plasma proteomics from 44,000+ UK Biobank participants reveals that the brain and immune system are powerful predictors of longevity. A youthful brain and immune system cut mortality risk nearly in half—more so than any other organ. This could reshape how we think about aging, diagnostics, and preventive medicine. 📊 Machine learning + blood proteins = next-gen aging biomarkers. 🔗 Study link: https://doi.org/10.1038/s41591-025-03798-1 #Longevity #Proteomics #BrainHealth #ImmuneSystem #Aging #Biomarkers #PrecisionMedicine #UKBiobank...
info_outline
Five to Thrive: Slash Your Cardiovascular Disease Risk ✋🛡️🧬
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
📣 New insights from a global study on cardiovascular disease! 🌍❤️ Even without traditional risk factors, your lifetime risk of CVD isn’t zero — but midlife action can add a decade or more of healthy life. 🧠💡 Key takeaway: Knowing is not enough — we must apply. 🩺📊✅ #CardiovascularHealth #PreventionMatters #GlobalHealth #PrecisionMedicine #PublicHealth 💪🌎🧬
info_outline
Fat Depot Drama: From Swell to Well 🏕️📉😊
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🔬 Just read a fascinating News & Views in Nature on how weight loss reshapes adipose tissue beyond just shedding fat! 🧬 Using single-nucleus RNA-seq and spatial profiling, researchers found that bariatric surgery reverses stress, inflammation, and senescence in fat depots—yet some immune memory lingers. 🧠🔥 A compelling case for adipose plasticity—and why cellular “memory” may be the key to sustained metabolic health. 💡💪 #ObesityResearch #AdiposeRemodeling #WeightLossScience #Senescence #PrecisionMedicine #Nature
info_outline
Sugar Switches: HFpEF’s Hidden Code 🧩🫀🧬
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧠💓 Just read a fascinating new study in Cell Metabolism (July 2025): dislocation of hexokinase 1 from mitochondria increases O-GlcNAcylation in endothelial cells — a hidden driver of HFpEF! Reversing this sugar-tagging with OGA overexpression or OGT inhibition restores heart function in mice. Precision metabolism meets cardiology. 🔬❤️🔥 #HFpEF #OGlcNAcylation #EndothelialDysfunction #CardioResearch #MetabolicTherapeutics #CellMetabolism
info_outline
Cats, Dogs, and Clarity 🐕🐈💡: The Cognitive Perks of Pet Ownership
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🐾 New Research Alert! 🧠 Owning a dog or cat may do more than warm your heart — it could help preserve your mind! 🐶🐱 A large 18-year study across Europe found that pet owners experienced slower cognitive decline, especially in memory and verbal fluency. 🧪 No boost seen with fish or birds 🐠🐦, but fur friends = brain gains! 🔗 Let’s rethink aging — with tails, not pills. #HealthyAging #PetScience #CognitiveHealth #Longevity #BrainHealth 🧓💡
info_outline
🧪🛡️ Stroke Shield: How Tirofiban Tips the Scales
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧠✨ New Stroke Breakthrough! The ASSET-IT trial shows that early infusion of tirofiban after thrombolysis significantly boosts recovery in noncardioembolic stroke patients — with 65.9% achieving excellent outcomes at 90 days vs 54.9% with placebo 📈💉 ✅ Improved function ⚠️ Slightly higher bleeding risk 🌏 Study conducted across 38 centers in China 📚 Read the trial in NEJM (July 2025) #Stroke #Tirofiban #Neurology #RCT #PrecisionMedicine #Thrombolysis #CardiovascularResearch
info_outline
🧠 Trinity & Truth: The Theological Legacy of Boethius 📜
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
📚✨ Just explored Boethius: The Consolation of Philosophy — a timeless journey from despair to divine reason. Written in prison, this masterpiece blends Roman philosophy with Nicene Christian theology, standing firm against Arianism. 🕊️⚖️ 🎧 Listen now: #Boethius #Theology #FaithAndReason #Podcast 💡🎙️📜
info_outline
Exercise Without Exercise? Betaine’s Magic Revealed! 🧘✨🧬”
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
💡 New Study Alert! 🏃♂️🧪 Kidney-derived betaine mimics long-term exercise—blocking TBK1, reducing inflammation, and reversing aging markers. This multi-omics human + mouse study uncovers betaine as a precision geroprotector for those who can’t hit the gym. 📈 A leap toward exercise mimetics in aging science! #Geroprotection #PrecisionMedicine #ExerciseScience #Betaine 🧬🧓🔥
info_outline🚨 New trial alert! In youth with type 1 diabetes, adding #SGLT2i 💊 (dapagliflozin) to insulin:
✅ Reduced glomerular hyperfiltration
✅ Lowered HbA1c 📉
✅ Boosted time-in-range ⏱️
😌 Safe with DKA precautions in place
📄 #ATTEMPTTrial | @NatureMedicine
🔗 https://doi.org/10.1038/s41591-025-03723-6