Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🔬 New Review Alert! 🫀 South Asians face one of the highest global burdens of premature heart disease — and Lp(a) may be the silent culprit. 📈 In a comprehensive JAHA 2025 review, researchers reveal how 25% of South Asians have dangerously elevated Lp(a) levels, doubling their risk of myocardial infarction. 🧬💥 Key takeaways: ✅ Lp(a) is genetically driven & unaffected by lifestyle ✅ Risk is underestimated by standard calculators ✅ Novel therapies (PCSK9i, siRNA, ASOs) are on the horizon ✅ One-time testing is now strongly recommended in all South Asians...
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📢 New insights on education & brain aging! 🧠📉 A mega-analysis across 33 countries (170K+ participants, 15K+ MRIs) shows 📚 higher education boosts baseline memory—but doesn’t slow brain aging or cognitive decline over time. ❌🧓 ✅ Early-life traits (like childhood cognition & environment) drive the advantage. 🔗 Education matters—but not in the way we thought. Full story: “Reevaluating the role of education on cognitive decline and brain aging” in Nature Medicine 🧬🌍 #CognitiveHealth #BrainAging #LifelongLearning...
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🧬 Just dropped: our latest podcast episode 🎙️ dives into Lipoprotein(a) and its powerful role in predicting vascular disease beyond the heart 🫀—including PAD 🦵 and stroke 🧠. 📊 Based on a massive UK Biobank study (n=460K+), high Lp(a) levels (≥150 nmol/L) were linked to: • 18% ↑ risk of PAD • 17% ↑ risk of carotid stenosis • 60% ↑ risk of major limb events ⚠️ Lp(a) is more than a lab value—it’s a Vascular Crystal Ball. #LipoproteinA #PAD #Stroke #VascularMedicine #PrecisionCardiology #CardioPodcast #Biomarkers #Atherosclerosis...
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🧠✨ Dive into the mind of Avicenna (Ibn Sina) — the Persian polymath who shaped medicine, metaphysics, and logic for centuries. From the Canon of Medicine to the Book of Healing, his legacy lives on in modern science and thought. 🎓📚 #Philosophy #Medicine #Avicenna
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📢 New Data Drop! 🫀💥 South Asian adults in the U.S. have an earlier and sharper rise in coronary artery calcium (CAC) — a silent marker of heart disease risk! 🇮🇳📊 In a first-of-its-kind study combining MASALA & DILWALE cohorts (n=2,743), 65% of South Asian men and 30% of women had CAC >0 by age 55 — and women catch up fast after menopause. 🚹➡️🚺 📌 Sex-specific CAC percentiles = smarter screening, better prevention. 💡 Time to rethink traditional risk calculators for this high-risk group. 🎙️ Podcast title: “Men First, Women...
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🚨 New Insights from Nature Medicine 🧠🍕 Can cookies and chips hijack your brain like cocaine? A compelling new article argues that ultra-processed food addiction mirrors classic substance use disorders — down to the cravings, compulsive use, and reward circuit disruption. With GLP-1 drugs bridging obesity and addiction treatment, is it time the DSM-5 recognized food addiction? 🧬 Science says yes. ⚖️ Policy is lagging. 📢 Let’s start the conversation. #FoodAddiction #UltraProcessedFoods #DSM5 #GLP1 #PublicHealth #Neuroscience #Obesity #HealthPolicy...
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🚨 New Hypertension Guidance Alert! 🩺💡 The British & Irish Hypertension Society now recommends treating all adults with sustained BP ≥135/85 mmHg—regardless of CVD risk—and targeting <130/80 mmHg within 6 months. No more waiting for risk scores to rise 📉⏳. This bold, evidence-backed move aligns with global trends 🌍 and aims to end therapeutic inertia for good. Let’s make treatment simpler, safer, and sooner! 💊✅ #Hypertension #Guidelines #PrimaryCare #Cardiology #PublicHealth
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🧠🏃♂️ Can running rewire the Alzheimer’s brain? New study in Nature Neuroscience shows how exercise transforms cell-specific gene expression in the dentate gyrus of AD mice! Using single-nucleus RNA-seq, researchers found that voluntary running reversed transcriptional dysregulation in key cell types—especially immature neurons, astrocytes, and microglia. 💡Highlights: ✅ Neurogenesis boosted ✅ Disease-associated microglia reprogrammed ✅ Novel astrocyte subpopulation rescued This could pave the way for targeted therapeutics rooted in the biology of...
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🚨 Statins & Diabetes: Dose Matters, But So Does Perspective 💊📉 A 2024 CTT Collaboration meta-analysis of 154,664 participants confirms: ✅ Statins modestly increase risk of diabetes (10% with moderate, 36% with high-intensity) 📈 Small upticks in HbA1c and glucose 🧪 But most new cases were already teetering near the threshold 🩺 Bottom line? Cardiovascular benefits far outweigh the diabetes risk. 💡 It’s a reminder: precision prevention is about balancing risk, not eliminating it. 📚 Ref: Lancet Diabetes Endocrinol 2024 | DOI: #Statins #Diabetes...
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🧬 Just explored a groundbreaking 50-year proteomic atlas that charts how our proteins evolve with age across 13 human tissues! 🧠 Key insights? Aging inflection around 50, transcriptome-proteome decoupling, amyloid buildup, and senoproteins like GAS6 & GPNMB driving vascular & systemic aging. 📊 Proteomic clocks, plasma biomarkers, and tissue-specific aging maps may redefine how we measure and manage aging. 🔗 Dive into the protein-powered future of aging science! #Proteomics #AgingResearch #Biomarkers #Senescence #PrecisionMedicine
info_outline🚨 Game-changing breakthroughs in chimaera research! 🧬💓
From beating human hearts grown in pig embryos to human organoids integrating into mouse intestines and brains via amniotic injection—two bold advances are reshaping the future of organ transplantation and regenerative medicine.
But with scientific promise comes ethical complexity. How far should we go in creating human–animal hybrids? What safeguards are needed?
👇 Join the conversation:
Are we building miracles—or crossing lines?
#StemCells #RegenerativeMedicine #Bioethics #ChimaeraResearch #Transplantation #FutureOfMedicine