Beyond Cholesterol 🌪️: 🇮🇳🩺: Lp(a)’s Reach in the South Asian Diaspora
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🔬 New Review Alert! 🫀 South Asians face one of the highest global burdens of premature heart disease — and Lp(a) may be the silent culprit. 📈 In a comprehensive JAHA 2025 review, researchers reveal how 25% of South Asians have dangerously elevated Lp(a) levels, doubling their risk of myocardial infarction. 🧬💥 Key takeaways: ✅ Lp(a) is genetically driven & unaffected by lifestyle ✅ Risk is underestimated by standard calculators ✅ Novel therapies (PCSK9i, siRNA, ASOs) are on the horizon ✅ One-time testing is now strongly recommended in all South Asians...
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🏫 Early Edge, Not Late Armor — Why Brain Aging Ignores Your Diploma
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
📢 New insights on education & brain aging! 🧠📉 A mega-analysis across 33 countries (170K+ participants, 15K+ MRIs) shows 📚 higher education boosts baseline memory—but doesn’t slow brain aging or cognitive decline over time. ❌🧓 ✅ Early-life traits (like childhood cognition & environment) drive the advantage. 🔗 Education matters—but not in the way we thought. Full story: “Reevaluating the role of education on cognitive decline and brain aging” in Nature Medicine 🧬🌍 #CognitiveHealth #BrainAging #LifelongLearning...
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📉 “Lp(a) is a Vascular Crystal Ball” 🚷🦿🛣️
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧬 Just dropped: our latest podcast episode 🎙️ dives into Lipoprotein(a) and its powerful role in predicting vascular disease beyond the heart 🫀—including PAD 🦵 and stroke 🧠. 📊 Based on a massive UK Biobank study (n=460K+), high Lp(a) levels (≥150 nmol/L) were linked to: • 18% ↑ risk of PAD • 17% ↑ risk of carotid stenosis • 60% ↑ risk of major limb events ⚠️ Lp(a) is more than a lab value—it’s a Vascular Crystal Ball. #LipoproteinA #PAD #Stroke #VascularMedicine #PrecisionCardiology #CardioPodcast #Biomarkers #Atherosclerosis...
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Dr. RR Baliga’s Philosophical Discourses: Avicenna (Ibn Sina) (Islamic World, 980–1037 CE) – The Book of Healing
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧠✨ Dive into the mind of Avicenna (Ibn Sina) — the Persian polymath who shaped medicine, metaphysics, and logic for centuries. From the Canon of Medicine to the Book of Healing, his legacy lives on in modern science and thought. 🎓📚 #Philosophy #Medicine #Avicenna
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Scan. Score. Prevent. 📊🧠💊: A New Era in South Asian Heart Health?
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
📢 New Data Drop! 🫀💥 South Asian adults in the U.S. have an earlier and sharper rise in coronary artery calcium (CAC) — a silent marker of heart disease risk! 🇮🇳📊 In a first-of-its-kind study combining MASALA & DILWALE cohorts (n=2,743), 65% of South Asian men and 30% of women had CAC >0 by age 55 — and women catch up fast after menopause. 🚹➡️🚺 📌 Sex-specific CAC percentiles = smarter screening, better prevention. 💡 Time to rethink traditional risk calculators for this high-risk group. 🎙️ Podcast title: “Men First, Women...
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🍕 Engineered, Addictive, Unregulated — Why Ultra-Processed Foods Deserve a DSM Diagnosis
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚨 New Insights from Nature Medicine 🧠🍕 Can cookies and chips hijack your brain like cocaine? A compelling new article argues that ultra-processed food addiction mirrors classic substance use disorders — down to the cravings, compulsive use, and reward circuit disruption. With GLP-1 drugs bridging obesity and addiction treatment, is it time the DSM-5 recognized food addiction? 🧬 Science says yes. ⚖️ Policy is lagging. 📢 Let’s start the conversation. #FoodAddiction #UltraProcessedFoods #DSM5 #GLP1 #PublicHealth #Neuroscience #Obesity #HealthPolicy...
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Hypertension: Treat Early, Treat All, Save More 💊🌍❤️
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚨 New Hypertension Guidance Alert! 🩺💡 The British & Irish Hypertension Society now recommends treating all adults with sustained BP ≥135/85 mmHg—regardless of CVD risk—and targeting <130/80 mmHg within 6 months. No more waiting for risk scores to rise 📉⏳. This bold, evidence-backed move aligns with global trends 🌍 and aims to end therapeutic inertia for good. Let’s make treatment simpler, safer, and sooner! 💊✅ #Hypertension #Guidelines #PrimaryCare #Cardiology #PublicHealth
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Neurons in Motion: Run, Repair, Rewire 🏃♂️🧠🔧” Exercise-induced neuroplasticity in Alzheimer’s disease
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧠🏃♂️ Can running rewire the Alzheimer’s brain? New study in Nature Neuroscience shows how exercise transforms cell-specific gene expression in the dentate gyrus of AD mice! Using single-nucleus RNA-seq, researchers found that voluntary running reversed transcriptional dysregulation in key cell types—especially immature neurons, astrocytes, and microglia. 💡Highlights: ✅ Neurogenesis boosted ✅ Disease-associated microglia reprogrammed ✅ Novel astrocyte subpopulation rescued This could pave the way for targeted therapeutics rooted in the biology of...
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💊 Dose, Diabetes & Destiny: The Statin Tradeoff
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚨 Statins & Diabetes: Dose Matters, But So Does Perspective 💊📉 A 2024 CTT Collaboration meta-analysis of 154,664 participants confirms: ✅ Statins modestly increase risk of diabetes (10% with moderate, 36% with high-intensity) 📈 Small upticks in HbA1c and glucose 🧪 But most new cases were already teetering near the threshold 🩺 Bottom line? Cardiovascular benefits far outweigh the diabetes risk. 💡 It’s a reminder: precision prevention is about balancing risk, not eliminating it. 📚 Ref: Lancet Diabetes Endocrinol 2024 | DOI: #Statins #Diabetes...
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🧓🏼 The Aorta Whispers First at age 50: Signals of Systemic Senescence
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧬 Just explored a groundbreaking 50-year proteomic atlas that charts how our proteins evolve with age across 13 human tissues! 🧠 Key insights? Aging inflection around 50, transcriptome-proteome decoupling, amyloid buildup, and senoproteins like GAS6 & GPNMB driving vascular & systemic aging. 📊 Proteomic clocks, plasma biomarkers, and tissue-specific aging maps may redefine how we measure and manage aging. 🔗 Dive into the protein-powered future of aging science! #Proteomics #AgingResearch #Biomarkers #Senescence #PrecisionMedicine
info_outline🫀 The Heart Ages—But Can We Intervene?
New insights from Nature Reviews Cardiology highlight how endothelial dysfunction, inflammageing, CHIP, and senescence-associated secretory phenotypes (SASP) drive cardiovascular ageing. Promising interventions—from gerotherapeutic diets and exercise to NAD+ boosters, senolytics, and ACBP neutralization—may help delay decline and promote resilience.
💡 Can we target the biology of ageing to extend cardiovascular healthspan, not just lifespan?
👇 Join the conversation: Which intervention holds the most promise—and what are the biggest challenges in translating this to clinical practice?
#Cardiology #Longevity #Geroscience #HeartHealth #Innovation #PrecisionMedicine #HealthyAgeing