Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐ก New Study Alert! ๐โโ๏ธ๐งช Kidney-derived betaine mimics long-term exerciseโblocking TBK1, reducing inflammation, and reversing aging markers. This multi-omics human + mouse study uncovers betaine as a precision geroprotector for those who canโt hit the gym. ๐ A leap toward exercise mimetics in aging science! #Geroprotection #PrecisionMedicine #ExerciseScience #Betaine ๐งฌ๐ง๐ฅ
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๐งฌ Rewinding Cellular Time with Chemistry! ๐งช A groundbreaking study just showed that a two-chemical cocktail (2c) โ Tranylcypromine + Repsox โ can reverse aging markers in human cells and extend C. elegans lifespan by 42%! ๐๐ฅ Unlike gene-based reprogramming, this method is safer, scalable, and preserves cell identity. Think of it as โYamanaka liteโ โ with big implications for aging and longevity science. ๐ง ๐ #Longevity #Epigenetics #Rejuvenation #Biotech #AgingResearch #Lifespan
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๐ถโโ๏ธ๐ Just recorded a podcast on Peripheral Artery Disease (PAD) โ a silent threat affecting 200M+ people worldwide. We unpack the latest 2024 ACC/AHA guidelines: โ When to screen ๐ What therapies work ๐ฆฟ How to save limbs & lives Tune in to walk away smarter. ๐ฃ๐๏ธ #PAD #Cardiology #Guidelines #Prevention #LimbSalvage
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
Just finished reviewing the latest JAMA 2025 article on osteoporosis by Morin et al. โ a must-read for anyone managing bone health in aging adults! ๐ Despite advances, 70% of fractures occur in those without DXA-defined osteoporosis. ๐ Treatment isnโt just about T-scores โ itโs about fracture risk, fall prevention, and smart sequencing of antiresorptive and anabolic therapies. ๐๏ธโโ๏ธ Plus, lifestyle matters: resistance training, calcium, vitamin D, and proactive screening save lives. ๐ Fracture Liaison Services (FLS) boost treatment initiation from 17%...
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๐จ New breakthrough in hypertension care! ๐ The Launch-HTN trial shows lorundrostat โ a selective aldosterone synthase inhibitor โ significantly lowers systolic BP in patients with uncontrolled or treatment-resistant hypertension. ๐ โ16.9 mmHg vs โ7.9 mmHg with placebo (P < .001) ๐งช Safe, well-tolerated, and effective across subgroups. A potential game-changer in aldosterone-targeted therapy! ๐๐ฅ #Hypertension #Cardiology #ClinicalTrials #PrecisionMedicine
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Our latest podcast episode unpacks the 2025 JAMA Review on Type 2 Diabetes ๐ฌ๐ We explore: โ New diagnostic strategies โ Why GLP-1s & SGLT2is are game-changers โ How lifestyle change can lead to remission โ Individualizing A1C goals in real-world care ๐๏ธ Episode Title: โDiagnose, Personalize, Optimize: The 2025 Diabetes Blueprintโ ๐ Essential listening for clinicians, educators, and innovators in endocrine & cardiometabolic care. ๐ Tune in now and share with your network! #Type2Diabetes #CardiometabolicCare #GLP1 #SGLT2...
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How we sleep tonight shapes how we move tomorrow! ๐๐โโ๏ธ In a large-scale wearable study (๐ฑWHOOP & Fitbit data from >25,000 adults), researchers found: โ Sleeping earlier than usual boosts next-day physical activity โ Longer or later sleep = less movement ๐ฅ Max gains came from consistent sleep duration + early bedtime Letโs rethink our ๐ค to power our ๐ฅ! ๐ฃ Public health campaigns should promote sleep and exercise togetherโnot in competition. ๐ PNAS, June 2025 | doi: #SleepHealth #PhysicalActivity #WearableTech #Chronobiology...
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๐งฌ Curious why we age? ๐ฐ๏ธ From DNA damage to developmental programs gone rogue, this new podcast episode dives deep into 17 theories of ageing โ some classic, some controversial. ๐ We explore wear-and-tear, free radicals, telomeres, mitochondria, stem cell exhaustion, and the rising stars of epigenetic drift and hyperfunction theory. ๐๏ธ Whether youโre a scientist, clinician, or just fascinated by the biology of time, tune in to uncover what really drives the ageing processโand what might one day slow it down. ๐ง Listen now: โWrinkle, Rust, and...
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Refractory Angina: Time to Rethink the Diagnosis ๐ซ๐ฅ Chest pain that defies stents and statins? It may not be your typical obstructive CAD. This podcast unpacks the redefinition of refractory angina โ spotlighting INOCA, CMD, vasospasm, and myocardial bridging ๐ฌโ๏ธ We explore PET, CMR, CFVR, and wire-based diagnostics ๐ โ and why a multidisciplinary Angina Heart Team is key to transforming care ๐ฉโโ๏ธ๐จโโ๏ธ๐ง ๐ง Listen in as we chart a course from frustration to precision โ because even stubborn angina has a story and a solution. ...
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๐ฌ๐ New insights from Nature Aging: Inflammaging isnโt universal! A fascinating cross-cultural study comparing Italy ๐ฎ๐น, Singapore ๐ธ๐ฌ, Bolivia ๐ง๐ด, and Malaysia ๐ฒ๐พ shows that age-related inflammationโlong considered a hallmark of agingโmay actually be a product of industrialized environments. Populations like the Tsimane (Bolivia) and Orang Asli (Malaysian), despite high infection loads, show minimal correlation between cytokines and age-related disease. ๐ Conclusion: Inflammaging is not destinyโitโs context. ๐งช Read the...
info_outline๐งฌ Rewinding Cellular Time with Chemistry! ๐งช
A groundbreaking study just showed that a two-chemical cocktail (2c) โ Tranylcypromine + Repsox โ can reverse aging markers in human cells and extend C. elegans lifespan by 42%! ๐๐ฅ
Unlike gene-based reprogramming, this method is safer, scalable, and preserves cell identity. Think of it as โYamanaka liteโ โ with big implications for aging and longevity science. ๐ง ๐
#Longevity #Epigenetics #Rejuvenation #Biotech #AgingResearch #Lifespan