213: Micro Minutes: When Bacteria Break the Rules
Let's Talk Micro
In this Micro Minutes episode, Luis breaks down classic microbiology traits that usually hold true, but not always. From indole-negative E. coli to non-swarming Proteus and oxidase-negative Pseudomonas, this quick episode highlights real-world exceptions that can catch techs and students off guard. Learn how to spot: Indole-negative E. coli (98% rule + inactive biotypes) Lactose-fermenting look-alikes like Citrobacter freundii Proteus species that don’t swarm Pseudomonas species that test oxidase negative A fast, practical reminder that no single biochemical test should...
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212: Micro Minutes: Sometimes MacConkey Lies
Let's Talk Micro
Welcome to the very first Micro Minutes, a new quick-hit series from Let’s Talk Micro designed for students, techs, and anyone who wants fast, practical microbiology insights in under 10 minutes. In this episode, we tackle a common misconception that microbiologists can make at the bench when interpreting a single plate: MacConkey agar. Many assume: “If it doesn’t grow on MacConkey, it’s not a gram-negative rod.” “If it does grow on MacConkey, it must be a gram-negative rod.” Both are wrong — and today we break down why. Stay connected with Let’s Talk Micro: Website:...
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211: At the Speed of AST: Diagnosing Resistance Faster
Let's Talk Micro
In the third installment of our special series in partnership with bioMérieux, Luis welcomes back Dr. Sonali Kalathiya, infectious diseases pharmacist and medical advisor at bioMérieux, to explore how innovation is accelerating antimicrobial susceptibility testing (AST). Together they dive into FAST AST—a phenotypic susceptibility test that delivers actionable results directly from positive blood cultures in hours instead of days. They discuss how this technology works, how it complements molecular testing, and how it’s transforming patient care, antimicrobial stewardship, and...
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210: IDWeek 2025 Highlights: From Bench to Bedside
Let's Talk Micro
Just back from IDWeek 2025 in Atlanta, Luis shares the sessions and posters that defined this year’s meeting — from next-generation sequencing and diagnostic stewardship to AI in the microbiology lab and new antimicrobials on the horizon. Tune in for insights on: NGS test utilization and stewardship New β-lactamase inhibitors like nacubactam AI’s growing role in clinical microbiology Tedizolid and the importance of optimizing existing agents 🎧 Whether you were in Atlanta or following from afar, this episode captures the energy and innovation of IDWeek — and what it...
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209: CLSI y resistencia antimicrobiana (In Spanish)
Let's Talk Micro
En este episodio en español de Let 's Talk Micro, el Dr. Germán Esparza Sánchez , microbiólogo clínico, miembro del CLSI y consultor de la OPS/OMS, comparte las actualizaciones más recientes del documento M100 y cómo impactan la práctica microbiológica. Desde la eliminación de puntos de corte para Burkholderia cepacia hasta los nuevos antibióticos como aztreonam-avibactam, durlobactam-sulbactam y cefiderocol, analizamos los retos de aplicar las guías del CLSI en los laboratorios latinoamericanos, las diferencias epidemiológicas regionales y la importancia de la educación continua...
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208: The Microbiome Center of Puerto Rico
Let's Talk Micro
Puerto Rico is entering a new era in microbiome research. In this episode, Luis speaks with Dr. Filipa Godoy-Vitorino about the newly established Microbiome Center of Puerto Rico — a hub designed to strengthen research, collaboration, and training across the Caribbean. Dr. Godoy-Vitorino shares how the center is helping scientists access expertise in bioinformatics and data analysis, offering bilingual workshops, and expanding representation of Caribbean populations in global microbiome studies. She also discusses the center’s vision to connect with international partners, support...
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207: Micro Lab and Stewardship: Collaboration in Action (Pt.2)
Let's Talk Micro
In this second half of our discussion with Dr. Erin McCreary and Dr. Hannah Creager, we dive deeper into how microbiology and antimicrobial stewardship teams collaborate to improve patient outcomes. They unpack how to prioritize breakpoint updates, the pros and cons of cascade reporting, and what nudges can do to guide better prescribing. Then we explore a powerful example of collaboration—the transition from MRSA agar to PCR across hospitals—and what it taught both teams about communication, resource sharing, and patient safety. Finally, Erin and Hannah reflect on lessons learned, first...
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206: Micro Lab and Stewardship: Collaboration in Action (Pt.1)
Let's Talk Micro
Good communication isn’t optional—it’s essential for patient care. In Part 1 of this two-part series, Dr. Erin McCreary and Dr. Hannah Creager join Luis to talk about how microbiology labs and antimicrobial stewardship teams can collaborate more effectively. They share real-world examples from their system-wide work—aligning AST panels and breakpoints across multiple platforms, navigating reporting challenges like the clindamycin D-test and rifampin comments, and building consistent communication through monthly micro–stewardship meetings. It’s a behind-the-scenes look at how...
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205: Complicated UTIs: The New IDSA Guidelines
Let's Talk Micro
The Infectious Diseases Society of America (IDSA) has released new guidelines for the treatment of complicated urinary tract infections. In this episode, we break down the key updates: Changes to the definition of complicated UTIs The role of newer antibiotic agents How and when to use antibiograms A four-step framework for guiding therapy When carbapenems are necessary—and when other options may be just as effective Shorter durations of therapy Join Dr. Barbara Trautner, Dr. Nicolas Cortés-Penfield, and Dr. Kalpana Gupta as they discuss what these guidelines mean for...
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204: In the Bloodstream: Diagnosing Infections Faster
Let's Talk Micro
Bloodstream infections can progress rapidly to sepsis—bringing high costs, high mortality, and lasting effects. In the second episode of this series in collaboration with bioMérieux, Luis speaks with Dr. Jeff Cies, Senior Medical Advisor at bioMérieux, about how molecular diagnostics are reshaping bloodstream infection diagnosis. They discuss: Limitations of traditional blood cultures How rapid molecular tests deliver results faster than ever The impact on outcomes, costs, and antimicrobial resistance The role of stewardship programs in maximizing results What the future...
info_outlineBloodstream infections can progress rapidly to sepsis—bringing high costs, high mortality, and lasting effects. In the second episode of this series in collaboration with bioMérieux, Luis speaks with Dr. Jeff Cies, Senior Medical Advisor at bioMérieux, about how molecular diagnostics are reshaping bloodstream infection diagnosis.
They discuss:
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Limitations of traditional blood cultures
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How rapid molecular tests deliver results faster than ever
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The impact on outcomes, costs, and antimicrobial resistance
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The role of stewardship programs in maximizing results
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What the future holds: direct-from-blood testing, nanotechnology, and AI
A powerful look at how innovation in microbiology is changing the fight against sepsis and saving lives.
This episode is sponsored by bioMérieux, a global innovator in infectious disease diagnostics.
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Website: letstalkmicro.com
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Questions or feedback? Email me at letstalkmicro@outlook.com
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