Dr. Baliga's 'Podkasts for Curious Docs'

Dr. Baliga's 'Podkasts for Curious Docs'

🚀 VESALIUS-CV delivers powerful evidence: in high-risk patients without prior MI or stroke, evolocumab significantly reduced 3-point MACE by 25% and 4-point MACE by 19%, with LDL-C lowered to a median of 45 mg/dL.   💡 These results expand the horizon of prevention, showing that deep LDL reduction is both safe and effective in averting first cardiovascular events.   🫀 Strong science. Clear signal. A new chapter in preventive cardiology.   #Cardiology #LDL #Prevention #VESALIUSCV

Dr. Baliga's 'Podkasts for Curious Docs'

🫀 Septic Shock, Refined at the Fingertips ⏱️   A powerful new JAMA (2025) trial brings us one step closer to truly personalized resuscitation. The ANDROMEDA-SHOCK-2 study shows that targeting capillary refill time (CRT) — a simple bedside sign — can shorten time on organ support vs usual care, without increasing mortality.   Key insight: Sometimes the most elegant solutions are low-tech, high-touch, and right at the bedside.   🧠 Precision 🤚 Physiology 💡 Pragmatism   #Sepsis #CriticalCare #PersonalizedMedicine #JAMA #Hemodynamics #ICU #Shock

Dr. Baliga's 'Podkasts for Curious Docs'

🚨 SOFA-2 arrives — a thoughtful evolution in critical care scoring 🧠🫁🫀   After nearly 30 years, the SOFA score has been modernized using data from >3.3 million ICU patients across 9 countries. The updated SOFA-2 incorporates contemporary respiratory and cardiovascular supports (HFNC, NIPPV, vasopressors, ECMO) and refines thresholds while preserving simplicity and bedside usability.   A meaningful step forward in describing organ dysfunction — with room for future biologically grounded refinement.   📖 Published in JAMA

Dr. Baliga's 'Podkasts for Curious Docs'

SOFA-2 is here — a major advance in assessing organ dysfunction in critical illness 🧠🫁❤️   Three decades after the original SOFA score, this updated framework reflects modern ICU practice — integrating contemporary organ support (ventilation, vasopressors, RRT), delirium recognition, and global feasibility across resource settings 🌍📊   Validated in 3.3M+ ICU patients across 9 countries — a remarkable effort in global critical care science 🏥📈   A powerful step forward in our shared language of severity and recovery.   🔗 JAMA Network Open, 2025

Dr. Baliga's 'Podkasts for Curious Docs'

💔 Peripartum Cardiomyopathy: When a Mother’s Heart Fights for Two   Peripartum cardiomyopathy is a leading yet often missed cause of maternal morbidity and mortality—striking late in pregnancy or months postpartum. Early suspicion, timely echo, and guideline-directed therapy save lives. 🩺   🧠 Bromocriptine, careful anticoagulation, and multidisciplinary care are reshaping outcomes, but global disparities persist. 🌍   Let’s amplify awareness, strengthen systems, and protect mothers everywhere. 🤝❤️   #HeartFailure #MaternalHealth #Cardiology...

Dr. Baliga's 'Podkasts for Curious Docs'

Rethinking “default lines” in the ICU 🧠🚑   A landmark NEJM trial shows that in patients with shock, deferring arterial catheterization and using automated cuff monitoring was noninferior for 28-day mortality — and reduced catheter-related complications.   A gentle reminder: not every sick patient needs a needle to be well cared for.   Precision isn’t only invasive — sometimes it’s thoughtful, measured, humane. 🌿💡   #CriticalCare #ICU #NEJM #Shock #Hemodynamics #PatientSafety

Dr. Baliga's 'Podkasts for Curious Docs'

🌙 Bright Nights, Higher Heart Risk ❤️‍🩹   New findings in JAMA Network Open highlight that greater exposure to artificial light at night is associated with significantly increased risks of coronary artery disease, myocardial infarction, heart failure, atrial fibrillation, and stroke — independent of sleep duration, lifestyle factors, and genetics.   💡 Clinical takeaway: Protecting circadian rhythms is cardiovascular prevention. Darker nights = healthier hearts.   🛌 Simple steps: blackout curtains, limit screens before bed, use warm/dim evening lighting....

Dr. Baliga's 'Podkasts for Curious Docs'

The immune clock starts earlier than we think ⏳🧬   A landmark Nature study shows that immune aging begins quietly in midlife — decades before clinical frailty.   Using >16M single-cell profiles and longitudinal vaccine responses, researchers found: • Stable, early transcriptional drift in naïve & memory T cells • A subtle TH2 shift that may weaken antiviral antibody quality • Reduced IgG class-switching to repeat flu antigens (e.g., B/Phuket) • No acceleration from CMV infection despite compositional shifts   The message? Immune aging is gradual, not...

Dr. Baliga's 'Podkasts for Curious Docs'

🫀 TAVR or SAVR? The 7-Year Truth   New 7-year results from the PARTNER-3 trial (NEJM) show that in low-risk patients with severe symptomatic aortic stenosis, TAVR holds pace with surgery — delivering comparable survival, stroke rates, rehospitalization, valve durability, and quality-of-life outcomes.   🔎 Highlights • Composite events: 34.6% (TAVR) vs 37.2% (SAVR) • Mortality: 19.5% vs 16.8% • Valve failure: 6.9% vs 7.3% • Aortic gradients remain low in both groups   💡 Clinical rhythm: less AF with TAVR; more pacemakers and paravalvular leak.   This study...

Dr. Baliga's 'Podkasts for Curious Docs'

🌿 Spinoza: Reason, Nature, Freedom   Today’s deck explores Baruch Spinoza — the quietly revolutionary Dutch philosopher who shaped rationalism, modern biblical criticism, and secular democracy.   He saw God = Nature, championed intellectual freedom, and argued that understanding our emotions transforms them — not far from cognitive-behavioral ideas we use in modern medicine.   His reminder feels timely: human flourishing grows where inquiry is free, passions are understood, and systems support dignity + reason.   🧠🔍💬 Clarity is liberation.