Quick Hits: The Women's Hormone Masterclass: A Deep Dive Into Testosterone, Dutasteride, SHBG, & Menopause Weight Gain with Dr. Kyle Gillett
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Release Date: 03/10/2026
The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Discover innovative therapies like low-dose naltrexone and light therapy that are reshaping the way we think about detoxification and healing. What are the unexpected benefits of these treatments, and how do they interact with our immune and endocrine systems? Get ready to explore cutting-edge insights that could transform your approach to wellness!...
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What happens when three menopause podcasters sit down together with zero intention of staying surface level? You get a smart, honest, hilarious, and deeply validating conversation about some of the biggest midlife topics women are trying to figure out right now. In this roundtable episode, we get into bone health, hormone testing, HRT mistakes, libido, trauma, desire, and the much bigger cultural story around what menopause is actually meant to be. We talk openly about why so many midlife women feel disconnected from sex, why female arousal is so misunderstood, and how much emotional baggage,...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full episode: Known as the “Menopause Educator and Researcher” to her 340,000+ TikTok followers, Andrea Donsky is a nutritionist on a mission to change the conversation around perimenopause and menopause. Her new book "Nourishing Menopause: Powerful Nutrition and Lifestyle Strategies to Feel Your Best" comes out May 5th! Our...
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In this episode, I sit down with Cynthia Thurlow, nurse practitioner, TEDx speaker, and author of The Menopause Gut, to unpack what is really happening inside the body during this transition. We get into why so many women suddenly feel bloated, constipated, reactive to foods, inflamed, and resistant to weight loss, even when they are eating well and doing all the “right” things. Cynthia breaks down the gut-hormone connection in a way that is smart, practical, and incredibly eye-opening. We also go deeper into leaky gut, digestive enzymes, bile, hydrochloric acid, short-chain fatty acids,...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Join our FREE upcoming masterclass: Why Midlife Weight Gain Won’t Budge A smarter way to use GLP-1s in midlife without wrecking muscle or metabolism When: April 30th 11 am PST Register here: Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Listen to the full episode here: Itunes: Christopher Shade, PhD, founder and CEO of Quicksilver Scientific, continues to be the driving force of...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Three years ago, GLP-1 peptides were barely being talked about in the midlife women’s health space. Since then, Jessica and I have personally used them, experimented with different approaches, and helped over a thousand women inside our peptide program navigate what works, what backfires, and what women in perimenopause and menopause need to know before jumping in. In this episode, we’re pulling back the curtain on our own GLP-1 journeys, including my rough start with Ozempic, why Tirzepatide worked better for me, Jessica’s experience with Semaglutide and fatigue, and why Retatrutide is...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Join our FREE upcoming masterclass: Why Midlife Weight Gain Won’t Budge A smarter way to use GLP-1s in midlife without wrecking muscle or metabolism When: April 30th 11 am PST Register here: There comes a point for so many women in their late 30s and 40s when they look in the mirror, or down at their belly, and think, what is happening to my body? You’re still eating well. You’re still exercising. You’re still trying to do all the “right” things. And yet your body suddenly feels like it is playing by a completely different set of rules. In this episode, I sit down with Dr....
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
In this second of two parts, I sit down with Victoria Felkar again to unpack the complicated, often glamorized world of androgens, testosterone therapy, and anabolic steroids for women. Are these hormones empowering tools—or ticking time bombs? How do you know the difference? We dive into what’s really happening beneath the surface when women start layering in testosterone or other androgens, especially without a solid hormonal foundation in place. Have you ever wondered why some women feel amazing on testosterone, while others spiral into acne, hair loss, mood swings, or worse? What role...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes. Today’s clip comes from one of our most replayed conversations. If you want the full episode, check the link in the description below. Have you ever wondered what your DNA says about your diet and hormones? Well in today's episode we are going to explore the connection between genetics and popular diets like keto, vegan, and low carb. Additionally, we'll explore how DNA reports can help us better understand our hormones and their impact on our health. Kashif Khan the Chief...
info_outlineThe Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health
In this episode, I’m joined by the brilliant Victoria Felkar, and we go where most conversations in women’s health simply don’t: anabolic steroids. Why has this topic been so misunderstood—and even feared—by women, especially in midlife? Are we lumping very different hormones into one “scary” category without truly understanding them? Victoria shares her own jaw-dropping health story—one that led to sky-high androgens, medical confusion, and even accusations of steroid use. How did a teenage experience with birth control, stress, and recovery from an eating disorder spiral...
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In this quick hits I sit down with Dr. Gillett, to exam the complex world of women's hormones today. We'll be focusing on androgens like testosterone, DHEA, and dihydrotestosterone, and their profound impact on female health. Dr. Gillett provides insights on the role of binding globulins, hormone replacement therapy, and the interplay between insulin and androgens. We also discuss the challenges of menopausal weight gain, the benefits of GLP-1 medications for weight loss, and practical strategies anyone can use for maintaining lean body mass.
In this episode we discuss:
- How androgens such as testosterone, DHEA, and dihydrotestosterone affect women's well-being.
- Why sex hormone binding globulin (SHBG) is critical for hormone dynamics and stability.
- Understanding the impact of thyroid binding globulin and cortisol binding globulin on hormone balance.
- How hormone replacement therapy (HRT) influences women's bodies, especially regarding androgens.
- Managing testosterone replacement therapy to avoid virilization symptoms like facial hair and voice changes.
- The role of DHT blockers in managing androgen-related conditions.
- How SHBG can be harnessed for overall hormone stability and health benefits.
- Challenges of menopausal weight gain and how hormonal changes affect body composition.
- Why integrating proper lifestyle habits is essential alongside GLP-1 medications for effective weight loss.
- How to maintain lean body mass through hormone therapy and lifestyle changes.
- How oral contraceptives and other synthetic hormones impact SHBG levels and overall hormone balance.
- The significance of SHBG levels for individuals on hormone replacement therapy or contraceptives.
- Exploring different forms of testosterone administration, including subcutaneous and intramuscular injections.
- How estrogen and progesterone influence testosterone levels through negative feedback inhibition.
- How poor sleep quality and hormonal changes contribute to menopausal weight gain.
- The paradoxical effects of hormone replacement therapy on body composition and fat gain.
- Why high SHBG must be paired with adequate hormone levels to avoid feeling unwell.
- Discussing the challenges faced when SHBG levels are artificially high due to medication.
Kyle Gillett https://gilletthealth.com/
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Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert