Neurology® at 75: The Evolution of the Neurology Journal
Neurology Minute
To celebrate 75 years of Neurology®, Dr. Chris Boes and Dr. José Merino discuss the journal’s history, its evolution, and what lies ahead for the future of Neurology®. Read more about the first .
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Navigating the Transition From Pediatric to Adult Epilepsy Care - Part 1
Neurology Minute
In part one of this series, Dr. Dara Albert and Dr. Scott Perry discuss what every neurology resident should know about caring for young adults with epilepsy as they transition from pediatric to adult neurology. Show citation: Perry MS, Nascimento FA, Pina-Garza JE, et al. Addressing Barriers to Transitioning Pediatric Patients With Epilepsy to Adult Health Care in the United States: A Narrative Review. Neurol Clin Pract. 2026;16(3):e200616. doi:
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June 22, 2026 Capitol Hill Report: Huge Milestone for Prior Authorization Bill
Neurology Minute
In this episode, Dr. Jonathan Crowe reviews the Capitol Hill Report from June 22nd, discussing milestones related to the Improving Seniors' Timely Access to Care Act. Stay updated with what’s happening on the hill by visiting . Learn how you can get involved with .
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Epilepsy Fundamentals Refresher Series - Part 3
Neurology Minute
In the third part of this series, Dr. Halley Alexander explores emerging trends and recent advances in epilepsy. Show citation: Tolchin B, Goldstein LH, Reuber M, et al. Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee. Neurology. 2026;106(1):e214466. doi: Hingray C, Popkirov S, Kozlowska K, et al. Functional/dissociative seizures: Proposal for a new diagnostic label and definition by the ILAE task force. Epilepsia. 2025;66(11):4162-4182. doi: Krauss GL, Elizebath R, Wheless SSJW, et al. Phase III...
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Epilepsy Fundamentals Refresher Series - Part 3
Neurology Minute
In the third part of this series, Dr. Halley Alexander explores emerging trends and recent advances in epilepsy. Show citation: Tolchin B, Goldstein LH, Reuber M, et al. Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee. Neurology. 2026;106(1):e214466. doi: Hingray C, Popkirov S, Kozlowska K, et al. Functional/dissociative seizures: Proposal for a new diagnostic label and definition by the ILAE task force. Epilepsia. 2025;66(11):4162-4182. doi: Krauss GL, Elizebath R, Wheless SSJW, et al. Phase III...
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Epilepsy Fundamentals Refresher Series - Part 2
Neurology Minute
In part two of this series, Dr. Halley Alexander discusses seizure types, epilepsy types, and the etiology of epilepsy. Show citations: Beniczky S, Trinka E, Wirrell E, et al. Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy. Epilepsia. 2025;66(6):1804-1823. doi: Beniczky S, Trinka E, Wirrell E, et al. A practical guide to the updated seizure classification 2025. Epileptic Disord. 2025;27(6):1087-1104. doi:
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Communication About Uncertainty During PD Diagnostic Consultations
Neurology Minute
Dr. Greg Cooper and Dr. Elisabeth Kurpershoek discuss how clinicians communicate uncertainty during Parkinson's disease diagnosis and how this impacts patient trust and understanding. Show citation: Hillen MA, Kurpershoek E, Huisman MHB, et al. Clinician Communication About Uncertainty During Parkinson Disease Diagnostic Consultations. Neurol Clin Pract. 2026;16(3):e200613. doi:
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Comparing Sensitivity of Nerve Biopsy, Skin Biopsy, and Fat Aspirate in ATTRv-PN
Neurology Minute
Dr. Katie Krulisky and Dr. Marcus Pinto discuss the diagnosis and management of hereditary ATTR amyloidosis. Show citation: Panrudkevich AH, Jones FJS, Shouman K, et al. Sensitivity of Nerve and Skin Biopsy and Fat Aspirate for Amyloid in Symptomatic Hereditary ATTR Amyloidosis With Peripheral Neuropathy. Neurology. 2026;106(11):e218033. doi:
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Epilepsy Fundamentals Refresher Series - Part 1
Neurology Minute
In part one of this series, Dr. Halley Alexander explores epilepsy diagnosis. Previously posted Neurology Minute episodes related to . Show citation: Fisher RS, Acevedo C, Arzimanoglou A, et al. ILAE official report: a practical clinical definition of epilepsy. Epilepsia. 2014;55(4):475-482. doi:
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Low Prevalence and Inconsistency of LRP4-IgG Detection in Suspected MG
Neurology Minute
Dr. Aaron Zelikovich discusses the frequency of LRP4-IgG in patients with suspected MG using different cell-based assay protocols. Show citation: Vacchiano V, Milano DC, Ricciardiello F, et al. Low Prevalence and Inconsistency of LRP4-IgG Detection in Suspected Myasthenia Gravis: A Multicenter CBA Comparison Neurology: Neuroimmunology & Neuroinflammation. 2026;13(3). doi:
info_outlineDr. Gregg Day and Drs. Sonia Vallabh and Eric Minikel discuss scientific insights and the future of prion disease treatment, highlighting the importance of early diagnosis, personalized medicine, and hope for affected families.
Learn about the clinical trial.
Learn more about the Prion Alliance.
Show transcript:
Dr. Gregg Day:
This is Gregg Day with Neurology Minute. I've just been speaking with Eric Minikel and Sonia Vallabh, a husband and wife team at the heart of the PRiSM trial, a first-in-human study of a prion protein-lowering, divalent, small-interfering RNA for patients with symptomatic prion disease. Eric and Sonia, could you provide us with a brief overview of the PRiSM trial and what this first-in-human study seeks to accomplish?
Dr. Eric Minikel:
The PRiSM trial is testing a short interfering RNA designed to bind the RNA that encodes the prion protein. That is the protein that causes Prion disease. We are at the heart of what causes this disease. Through doing this, we hope to make prion disease a treatable and preventable condition. We both want to stabilize symptomatic patients and prevent the disease in people who are at genetic risk. This is a personal mission for us. Sonia is a carrier of a prion disease mutation that she inherited from her mother who died of prion disease, and we, along the way, aspire to be a different kind of sponsor. We want to create our own clinical data that are shareable learnings for the entire field.
Dr. Gregg Day:
This is Gregg Day with Neurology Minute. Thanks for listening.