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Sir Bruce Keogh on the NHS at 70, TopMedTalk Classics

TopMedTalk

Release Date: 06/01/2026

EBPOM 2026: Research oral abstract finalists show art EBPOM 2026: Research oral abstract finalists

TopMedTalk

Joff Lacey and Imogen Fecher-Jones interview six oral abstract finalists at this years' EBPOM. Nora Cruz Rodriguez; Association Between Participation in Remote Prehabilitation and High-Dependency Unit Length of Stay After Oesophagectomy and Radical Cystectomy: A Retrospective Cohort. Alexios Dosis; Remote wearable monitoring as a preoperative risk assessment tool. Ned Douglas; The Fluids, Atomoxetine or Midodrine (FAME) pilot trial. Tom Scoellaro; The new normal: CPET findings in patients aged 80 years and older. Gerry O'Callaghan; Preventing and Reducing Re-Presentations and Admissions...

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TopMedTalk

This month’s TopMedTalk Classic is particularly topical: first broadcast back in 2018 but relevant once again after the recent news of an Ebola outbreak in the Democratic Republic of the Congo. Originally recorded at the Intensive Care Society State of the Art Meeting in London, Desiree Chappell and Monty Mythen speak with Dan Martin, OBE, now Professor at the University of Plymouth and Consultant in Intensive Care Medicine at University Hospitals Plymouth NHS Trust, about the critical care management of Ebola and other viral haemorrhagic fevers. Dan Martin describes the Royal Free...

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TopMedTalk

This piece is essential listening for anyone interested in modern academic publishing. Recorded at the Collaborative Clinical Trials Meeting in Prato, Italy, TopMedTalk hosts Kate Leslie and Mike Grocott speak with Eric Rubin (Editor-in-Chief, New England Journal of Medicine) and Jocalyn Clark (International Editor, BMJ) about medical publishing. The conversation covers, engaging with clinical researchers and seeing impactful work. How AI can help authors—especially non-native English speakers—while raising concerns about confidentiality, inaccurate or fabricated content, reviewer misuse,...

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Perioperative Profile: Bruce Biccard show art Perioperative Profile: Bruce Biccard

TopMedTalk

Live from the World Congress of Anesthesiologists in Marrakesh, Kate Leslie speaks with Bruce Biccard, Nuffield Professor of Anaesthetic Science at the University of Oxford, Director of the African Perioperative Research Group, and board member of IARS and Safe Surgery South Africa. Bruce reflects on growing up in apartheid-era Cape Town, training in anaesthesia amid high-acuity care including trauma and HIV, and developing an interest in research through perioperative beta-blocker studies and mentorship in Oxford. He describes building South African and pan-African research collaborations...

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TopMedTalk

At Euroanaesthesia in Rotterdam, TopMedTalk hosts Andy Cumpstey and Kate Leslie speak with Joana Berger-Estilita, ESAIC chair of education and training, about ESAIC’s new leadership program. Developed over two years with a multidisciplinary team including ESAIC leadership and headquarters staff, the pilot addresses a gap for seasoned anaesthesiologists seeking further career progression. The retreat-style, experiential course includes two extended weekends (December and March), selects 25 ESAIC members with at least five years post-training leadership experience, and pairs participants with...

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TopMedTalk

At the World Congress of Anaesthesiologists (WCA) in Marrakech, Morocco, TopMedTalk co-editors In chief, Kate Leslie and Mike Grocott speak with Sydney anaesthesiologist Alwin Chuan, a member of the joint ESRA-ASRA working group on AI, about strengths and limitations of AI for regional anaesthesia and medicine. Chuan explains how generative AI is trained on vast datasets using transformer architectures, why outputs are probabilistic, and how context affects meaning. They discuss privacy and the possibility of personal or creative work being used as a commodity in training, internet...

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Euroanaesthesia 2026: Breaking Trials about Perioperative Blood Pressure Targets show art Euroanaesthesia 2026: Breaking Trials about Perioperative Blood Pressure Targets

TopMedTalk

At Euroanaesthesia in Rotterdam, TopMedTalk hosts Andy Cumpsty and Kate Leslie speak with Denise Veelo Professor of Anesthesiology at the Amsterdam University Medical Center and Bernd Saugel Professor of Anesthesiology and Vice Chair of the Department of Anesthesiology in the Center of Anesthesiology and Intensive Care Medicine at the University Medical Center Hamburg-Eppendorf, about two JAMA blood-pressure trials published on the same day. Veelo describes a 3,500-patient, two-center randomized trial comparing usual care (MAP 65) with more intensive, risk-stratified higher MAP thresholds...

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TopMedTalk

At this year’s Euroanaesthesia meeting in Rotterdam, TopMedTalk host Andy Cumpsty interviews Wolfgang Buhre, Professor of Anesthesia and Perioperative Medicine at Utrecht University Medical Center and past president of the European Society of Anaesthesiology and Intensive Care (ESAIC). The discussion starts with a focus upon the annual ESAIC congress and its international reach, with next year’s meeting planned for Copenhagen. Buhre explains ESAIC’s White Paper, developed over two years using interviews and desk research with clinicians, stakeholders, and patient perspectives, to clarify...

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TopMedTalk

Andy Cumpstey and Mike Grocott interview Kate Leslie about the SNaPP study (Sugammadex, Neostigmine, and Postoperative Pulmonary Complications). SNaPP is a pragmatic randomized study run from the University of Melbourne with the ANZCA Clinical Trials Network across 45 sites in Australia, New Zealand, and Hong Kong. Patients aged 40+ having major abdominal or thoracic surgery (≥2 hours, overnight stay) were randomized after induction to reversal with sugammadex or neostigmine, with anesthetists unblinded and encouraged to use quantitative neuromuscular monitoring. In this podcast Andy, Mike...

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ANZCA meeting convenor and cultural advisor show art ANZCA meeting convenor and cultural advisor

TopMedTalk

At the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists (ANZCA) and Faculty of Pain Medicine (FPM) held in Auckland, New Zealand, Kate Leslie and Andy Cumpstey interview the annual scientific meeting convenor Kerry Benson-Cooper and conference cultural advisor Tui Blair about planning the meeting and how Māori traditions and culture have informed not only the conference but also patient care and education in New Zealand. Dr Kerry Benson-Cooper is a specialist anaesthetist and intensive care physician at Te Toka Tumai Auckland Hospital, New Zealand. Tui...

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TopMedTalk introduces our new “TopMedTalk Classics” series with a classic TopMedTalk episode from 2018 that is still prescient today. This lecture, given by Sir Bruce Keogh marked the NHS’s 70th birthday, a time framed by political volatility, financial constraint, rising demand, and shifting public expectations.

Keogh argues healthcare systems must adapt, highlighting the UK’s strengths in medical science, innovation, life sciences, and the scale and complexity of the NHS. He describes quality improvement efforts since 2008, including defining quality as effectiveness, safety, and patient experience, developing outcomes measures, and using aligned clinical and managerial leadership to drive change.

Examples include major reductions in MRSA, rapid increases in VTE assessment, improved survival from major trauma networks, better hip-fracture care, strong heart-attack and sepsis performance, stroke centralization benefits, and increased dementia diagnosis for support. He emphasizes future pressures from ageing, prevention, the health–social care split, Brexit workforce and drug costs, and emerging forces like mobile tech, AI, genomics, and gene therapy, arguing the NHS’s pooled, universal model is well suited to a genomics-enabled future.

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Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London.

Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood.

Register here -

https://ebpom.org/product/ebpom-world-congress-2026/

00:00 TopMed Talk Intro
00:18 Classics Episode Setup
01:31 Introducing Sir Bruce
02:23 Politics And Adaptation
04:41 Global Pressures On Healthcare
05:48 Hard Times Build NHS
07:35 UK Innovation Advantage
10:33 NHS Scale And Complexity
12:27 Darzi Review Quality Drive
16:10 Outcomes Framework Explained
17:20 Safety And High Level Metrics
18:09 MRSA Turnaround Lesson
20:11 Mandating VTE Prevention
22:58 Trauma Networks Results
24:08 Hip Fracture Best Practice
25:21 Heart Attack Care Wins
26:17 Sepsis And Early Warning
28:01 Stroke Centralization Success
28:45 Dementia Targets Debate
30:31 Leadership And Brexit Risks
32:35 Health And Social Care Split
36:01 Tech Disruption Ahead
36:49 Genomics And NHS Values
38:00 Closing And Congress Promo