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The DRAIN Trial

Neurology Minute

Release Date: 07/15/2026

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Dr. Justin Abbatemarco and Sukhun Kang discuss seeding trials and other hidden marketing tactics in clinical trials, and their implications for clinical practice and patient care.  Show citation:  Kang S, Lin I, Ekblom M, and Chang S. Clinical trials that are actually marketing ploys targeting doctors – how seeding trials put profit over patients. The Conversation. 2026;6(5). doi:

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Dr. Margarita Fedorova discusses the DRAIN trial and the efficacy of acetazolamide in idiopathic normal pressure hydrocephalus.  Show citation:  Virhammar J, Fasth O, Ekblom M, et al. Safety, tolerability, and efficacy of acetazolamide in idiopathic normal pressure hydrocephalus (DRAIN) in Sweden: a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Neurol. 2026;25(6):550-559. doi: 

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To celebrate 75 years of Neurology®, Dr. Chris Boes and Dr. José Merino discuss the journal’s history, its evolution, and what lies ahead for the future of Neurology®.   Read more about the first .   

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Navigating the Transition From Pediatric to Adult Epilepsy Care - Part 1 show art Navigating the Transition From Pediatric to Adult Epilepsy Care - Part 1

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In part one of this series, Dr. Dara Albert and Dr. Scott Perry discuss what every neurology resident should know about caring for young adults with epilepsy as they transition from pediatric to adult neurology. Show citation:  Perry MS, Nascimento FA, Pina-Garza JE, et al. Addressing Barriers to Transitioning Pediatric Patients With Epilepsy to Adult Health Care in the United States: A Narrative Review. Neurol Clin Pract. 2026;16(3):e200616. doi: 

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In the third part of this series, Dr. Halley Alexander explores emerging trends and recent advances in epilepsy.  Show citation:  Tolchin B, Goldstein LH, Reuber M, et al. Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee. Neurology. 2026;106(1):e214466. doi:  Hingray C, Popkirov S, Kozlowska K, et al. Functional/dissociative seizures: Proposal for a new diagnostic label and definition by the ILAE task force. Epilepsia. 2025;66(11):4162-4182. doi: Krauss GL, Elizebath R, Wheless SSJW, et al. Phase III...

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Dr. Margarita Fedorova discusses the DRAIN trial and the efficacy of acetazolamide in idiopathic normal pressure hydrocephalus. 

Show citation: 

Virhammar J, Fasth O, Ekblom M, et al. Safety, tolerability, and efficacy of acetazolamide in idiopathic normal pressure hydrocephalus (DRAIN) in Sweden: a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Neurol. 2026;25(6):550-559. doi:10.1016/S1474-4422(26)00126-2