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77. Professor Tim Spector: Your Gut Bacteria Control Your Health More Than Your DNA

Extend Podcast with Darshan Shah, MD

Release Date: 07/15/2025

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77. Professor Tim Spector: Your Gut Bacteria Control Your Health More Than Your DNA show art 77. Professor Tim Spector: Your Gut Bacteria Control Your Health More Than Your DNA

Extend Podcast with Darshan Shah, MD

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More Episodes

Your doctor says your health problems are genetic, so you're destined for the same fate. But what if that's completely wrong?

In this episode of Extend, I'm joined by Professor Tim Spector, one of the world's leading microbiome researchers, to reveal the truth: your gut bacteria have more control over your health than your genes do.

We explore Tim's 30-year twin study that turned modern medicine upside down, the devastating effects of antibiotics on your internal ecosystem, and why ultra-processed foods are as dangerous as cigarettes. We also dive into why 95% of Americans are dangerously fiber-deficient, and how fermented foods can reduce inflammation like natural steroids.

 

Professor Tim Spector is a genetic epidemiologist at King's College London, co-founder of Zoe, and author of multiple bestselling books on the microbiome. His research on 16,000 twins has revolutionized our understanding of how gut health trumps genetics in determining health outcomes.

 

We Also Discuss:

(02:18) 30 Years of Twin Research: The Study That Changed Everything 

(08:35) The Antibiotic Crisis: Why Your Childhood Meds Are Still Hurting You 

(11:31) C. Diff and the First Clue About Good vs. Bad Bacteria 

(22:40) Why Your Gut Microbiome Matters More Than Your Genetics 

(30:30) The Hidden Connection Between Gut Health and Autoimmune Disease 

(35:39) Ultra-Processed Foods: The Modern Cigarette Industry 

(43:51) Why 95% of Americans Are Fiber-Deficient (And Obsessed with Protein) 

(58:58) The 30 Plants Challenge: Diversity Over Restriction 

(01:05:22) Sourdough Secrets: Real vs. Fake (Most Is Fake) 

(01:13:46) Inside the Zoe Kit: Personalized Nutrition Based on Your Biology 

(01:19:53) GLP-1 Drugs: The Perfect Window for Gut Health Reset 

(01:27:36) Prebiotics vs. Probiotics vs. Postbiotics: What Actually Works 

(01:41:29) The Food for Life Cookbook: 100 Recipes for Your Microbiome

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Learn more about Dr. Shah:


Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram: https://www.instagram.com/darshanshahmd/



Learn more about Professor Tim Spector:

Instagram: @tim.spector

Website: https://zoe.com/en-us 

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