loader from loading.io

#179 The Truth About TRT and Estrogen

Hart2Heart with Dr. Mike Hart

Release Date: 06/12/2025

#205 Stop Nighttime Peeing show art #205 Stop Nighttime Peeing

Hart2Heart with Dr. Mike Hart

In this solo episode, Dr. Mike discusses the common issue of nocturia, where individuals frequently wake up at night to urinate, which disrupts sleep. The episode covers the root causes including sleep apnea, enlarged prostate, and overactive bladder, and dives into the roles of antidiuretic hormone (ADH) and atrial natriuretic peptide (ANP). It provides a comprehensive guide on addressing nocturia through behavioral modifications such as fluid restriction and sleep hygiene, supplements like pumpkin seed extract and beta-sitosterol, and pharmaceuticals including Desmopressin and...

info_outline
#204 Resetting Dopamine for Monogamy show art #204 Resetting Dopamine for Monogamy

Hart2Heart with Dr. Mike Hart

In this solo episode, Dr. Mike delves into the complex relationship between dopamine, romantic relationships, and the Coolidge Effect. The discussion highlights why men often feel the need for a new partner due to a desensitization of dopamine and how our overstimulated lifestyles contribute to this issue. The host explores the impact of modern habits on dopamine levels, the importance of boredom for resetting dopamine sensitivity, and the role of anticipation in maintaining desire. Practical solutions like dopamine resets, engaging in effort-based activities, and ensuring personal growth and...

info_outline
#203 Rethinking 10k Steps show art #203 Rethinking 10k Steps

Hart2Heart with Dr. Mike Hart

In this episode, Dr. Mike Hart delves into the origins and contemporary relevance of the 10,000 steps rule. He discusses the latest research outcomes from a massive meta-analysis comparing daily step counts from 2,000 to 12,000 steps and their associated health benefits. Listeners will learn about the significant reductions in mortality, cardiovascular disease, cancer mortality, dementia, depression, and type 2 diabetes risk achieved by increasing daily steps. The episode also provides insights into the importance of breaking up sedentary periods, the physiological differences between various...

info_outline
#202 Better Alternatives To Metformin show art #202 Better Alternatives To Metformin

Hart2Heart with Dr. Mike Hart

In this solo episode, the host discusses the effects of metformin, berberine, and dihydroberberine on exercise adaptation and longevity. While metformin is known for its longevity benefits and is popular in the biohacking community, it has been shown to significantly reduce exercise adaptations and VO2 max gains. Berberine, a supplement with similar effects to metformin, is easier to obtain but still has some negative effects on exercise and significant GI side effects. The episode introduces dihydroberberine (DHB), a compound with fewer GI issues and less impact on exercise adaptation, making...

info_outline
#201 Building True Mental Toughness with Tony Ricci show art #201 Building True Mental Toughness with Tony Ricci

Hart2Heart with Dr. Mike Hart

In this episode of the Heart to Heart podcast, Dr. Mike Hart chats with Tony Ricci, an athletic performance and mental health coach for athletes. Tony shares his fascinating journey from studying exercise physiology to working with elite athletes like MMA fighter Chris Weidman. They discuss the critical impact of mental resilience on athletic performance, practical strategies for mental and physical training, and bridging the gap between nutrition, conditioning, and mental skills training. Additionally, the conversation touches on the role of technology like HRV and sleep tracking in athlete...

info_outline
#200 Rethinking LDL and Longevity with Greg Mushen show art #200 Rethinking LDL and Longevity with Greg Mushen

Hart2Heart with Dr. Mike Hart

In this episode of the Heart to Heart Podcast, Dr. Mike Hart sits down with Greg Mushen, a former tech professional turned health advocate, to discuss his incredible journey of transforming his body and lifestyle. Greg shares insights from his background growing up in a medical family and how early exposure to health experiments sparked his long-lasting interest in nutrition and fitness. He details his significant body transformation starting at age 47, the role of tracking macros and engaging in strength training, and the importance of key habits like walking 17,000 steps a day. The...

info_outline
#199 How to Train Like a Pro Fighter with Dr. Corey Peacock show art #199 How to Train Like a Pro Fighter with Dr. Corey Peacock

Hart2Heart with Dr. Mike Hart

In this episode of the Heart to Heart podcast, Dr. Mike Hart interviews Dr. Corey Peacock, an exercise physiologist and department chair at Nova Southeastern University. Dr. Peacock discusses his diverse background, from establishing the Fight Science Laboratory to working with elite MMA fighters at Kill Cliff Fight Club. The conversation covers advanced training methods, including zone-based cardio, strength and conditioning exercises, and recovery protocols. Listeners gain insights into the importance of athletic balance, the role of power versus strength in MMA, and the efficacy of various...

info_outline
#198 How to Reverse Insulin Resistance show art #198 How to Reverse Insulin Resistance

Hart2Heart with Dr. Mike Hart

In this solo podcast episode, Dr. Mike Hart delves into the intricacies of insulin resistance, a prevalent yet misunderstood condition. The episode covers the fundamental role of insulin, what happens during insulin resistance, and its linkage to various diseases like diabetes and heart disease. It includes a detailed discussion on how to measure insulin resistance using markers like triglyceride to HDL ratio, fasting insulin, fasting glucose, and hemoglobin A1c. Dr. Hart also explains the significance of advanced glycation end products (AGEs) and how they contribute to aging and diabetes....

info_outline
#197 Why Your Brain Needs Friends with Dr. Ben Rein show art #197 Why Your Brain Needs Friends with Dr. Ben Rein

Hart2Heart with Dr. Mike Hart

  In this episode, host Dr. Mike Hart welcomes neuroscientist and author Dr. Ben Rein to discuss his new book, 'Why Brains Need Friends: The Neuroscience of Social Connection.' Dr. Rein shares his journey in neuroscience, his research on autism and MDMA, and his pivot towards science communication. They delve into the devastating effects of loneliness, comparing its impact on mortality to smoking 15 cigarettes a day, and explore why human connections are critical for our brain health. Dr. Rein also discusses the benefits of having pets, the intricate balance of social interactions across...

info_outline
#196 Rethinking Protein and Recovery with Dr. Jose Antonio show art #196 Rethinking Protein and Recovery with Dr. Jose Antonio

Hart2Heart with Dr. Mike Hart

  In this episode of the Heart to Heart podcast, Dr. Mike Hart chats with Dr. Jose Antonio about the evolution and impact of sports nutrition research, particularly focusing on creatine and protein consumption. Dr. Antonio shares his journey from studying muscle physiology to pioneering research in sports nutrition, highlighting the initial skepticism in the scientific community and the eventual acceptance of supplements like creatine. They also delve into the benefits of various supplements for athletic performance, the ongoing debates in the medical field regarding supplementation, and...

info_outline
 
More Episodes

Are testosterone injections destroying your hair—or your sex drive? In this no-nonsense episode of Hart2Heart, Dr. Mike Hart welcomes back men's health coach Ali Gilbert for a deep dive into testosterone replacement therapy (TRT), estrogen panic, and what’s really driving results in men’s health. They explore the truth about DHT and Finasteride, the emotional and physical effects of HCG, the difference between injections vs. creams, and the most common mistakes men make when trying to optimize hormones. Plus: how your cardio might be more anabolic than you think. Ali also shares her personal journey through breast implant illness and recovery, offering a cautionary tale about intuition, inflammation, and medical gaslighting. Whether you're navigating hormone therapy or just trying to feel better and think clearer, this episode is packed with gold.

Ali Gilbert is a men’s health expert and founder of Silverback Coaching, specializing in concierge fitness and hormone optimization for men. With over two decades of experience, Ali has become known as the "Queen of Men's Health" for her integrative approach to training, TRT education, and lifestyle management. She’s a speaker, educator, and creator of the Silverback Summit—a conference devoted entirely to cutting-edge men’s health practices.

Follow Ali Gilbert:

Show Notes:
00:00 Welcome back + introducing Ali Gilbert
01:00 Breast Implant Illness: Ali’s personal story
07:00 Symptoms and recovery from removal
10:00 The thyroid link and post-op results
12:00 Educating partners on TRT
14:45 Estrogen, aggression, and calming effects
16:30 The DHT misunderstanding
20:00 Injectable vs cream testosterone
22:00 Frequency, compliance, and optimal protocols
26:00 The truth about HCG and testicle size
30:00 Estrogen panic and Arimidex overuse
35:00 Why high estrogen symptoms are misunderstood
38:00 Aromatase in fat tissue + insulin resistance
41:00 Androgen receptor sensitivity and testing
44:00 The hype and limits of injectable l-carnitine
47:00 Zone 2 cardio and why it’s anabolic
51:00 How to train for longevity, not ego
55:00 Weak handshakes, posture, and presence
58:00 Flat benching: the shoulder destroyer?
59:00 Final thoughts and Silverback Summit info

 

Follow Dr. Mike Hart:

 

Thank you for listening!