#190 Optimizing Health and Performance with Peptides and Hormone Replacement: Insights from Dr. Chester Sokolowski

In this episode of the Heart to Heart podcast, Dr. Mike Hart hosts Dr. Chester Sokolowski, a peptide expert and the founder of Thrive Telehealth Clinic, which specializes in hormone replacement therapy (HRT) and peptide treatments for both men and women. Dr. Sokolowski discusses his background, career, and various business ventures focused on human performance and optimization. The conversation delves deep into the benefits and applications of testosterone replacement therapy (TRT), peptides, and other health-related topics. Key points include the implications of TRT, managing estrogen levels, the benefits of combining peptides for muscle growth and recovery, and the groundbreaking potential of GLP-1 agonists like Ozempic and Retatrutide for weight loss and metabolic health. Dr. Sokolowski also touches on the benefits of glutathione, the latest research on peptides such as BPC-157 and TB-500, and the ethical considerations of using these therapies in professional sports.

Dr. Chester Sokolowski is a performance optimization expert, telehealth clinician, and leading voice in hormone and peptide therapy. He earned his doctoral training at Florida State University and has dedicated his career to human performance, healthspan, and longevity.

Known online as “Dr. Soko”, he shares cutting-edge insights on testosterone therapy, peptides, recovery, and performance through social media and educational content. His work empowers people to look, feel, and perform at their absolute best.

Follow him on Instagram: @dr.soko, LinkedIn: Dr. Chester Sokolowski and YouTube: Dr. Soko

Links:

TRT (Testosterone Replacement Therapy)

Ozempic (Semaglutide)

DIM (Diindolylmethane)

Oxidative stress & disease

 

Show Notes:

• (00:00) Introduction to the Heart to Heart Podcast

• (02:30) Dr. soko's dissertation on binge drinking and muscle growth

• (06:00) Cold therapy and hypertrophy

• (08:00) TRT and arimidex discussion

• (13:35) “Estrogen is not the enemy; it’s actually protective for your heart, your brain, your joints.”

• (14:30) HCG and fertility

• (20:00) Peptides and GLP-1 drugs

• (34:30) Minimizing side effects and dosage strategies

• (35:30) Understanding GLP-1 mechanisms

• (36:00) Red aide: the unique GLP-1

• (39:00) Visceral fat and GLP-1 effectiveness

• (41:00) GLP-1s and impulse control

• (46:30) Glutathione: the ultimate antioxidant

• (50:30) Peptides for skin and hair health

• (51:00) Growth hormone peptides: which is best?

• (55:00) BPC-157 and tb-500: healing peptides

• (01:00:30) TRT, peptides, and sports

• (01:03:00) Conclusion and contact information

 

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The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to 

cutting through the noise and uncovering the most effective strategies for optimizing health, 

longevity, and peak performance. This podcast dives deep into evidence-based approaches to 

hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise 

protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.

 

Beyond health science, we tackle the intersection of public health and politics, exposing how 

policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.

 

Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary 

(Commissioner of the Food and Drug Administration (FDA) and high-profile names such as 

Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).

 

If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.

 

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